trans-BAY-850

Cat. No.: HY-119254A: FAQs
Data Sheet Handling Instructions

Molarity Calculator

trans-BAY-850 is the trans isomer of BAY-850 (HY-119254). BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC₅₀ of 166 nM.

For research use only. We do not sell to patients.

trans-BAY-850 Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of trans-BAY-850:

BAY-850 Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

654.24

Formula

C₃₈H₄₄ClN₅O₃

SMILES

O=C(N[C@H](CC1=CC=C(C#N)C=C1)CN[C@@H]2CC[C@@H](N)CC2)C3=CC(C4=CC=C(CN[C@@H](C5=CC=C(C)C=C5)C)O4)=C(OC)C=C3Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (152.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5285 mL	7.6425 mL	15.2849 mL
5 mM	0.3057 mL	1.5285 mL	3.0570 mL
10 mM	0.1528 mL	0.7642 mL	1.5285 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Fernández-Montalván AE, et al. Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action. ACS Chem Biol. 2017 Nov 17;12(11):2730-2736. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5285 mL	7.6425 mL	15.2849 mL	38.2123 mL
	5 mM	0.3057 mL	1.5285 mL	3.0570 mL	7.6425 mL
	10 mM	0.1528 mL	0.7642 mL	1.5285 mL	3.8212 mL
	15 mM	0.1019 mL	0.5095 mL	1.0190 mL	2.5475 mL
	20 mM	0.0764 mL	0.3821 mL	0.7642 mL	1.9106 mL
	25 mM	0.0611 mL	0.3057 mL	0.6114 mL	1.5285 mL
	30 mM	0.0509 mL	0.2547 mL	0.5095 mL	1.2737 mL
	40 mM	0.0382 mL	0.1911 mL	0.3821 mL	0.9553 mL
	50 mM	0.0306 mL	0.1528 mL	0.3057 mL	0.7642 mL
	60 mM	0.0255 mL	0.1274 mL	0.2547 mL	0.6369 mL
	80 mM	0.0191 mL	0.0955 mL	0.1911 mL	0.4777 mL
	100 mM	0.0153 mL	0.0764 mL	0.1528 mL	0.3821 mL

trans-BAY-850 Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

trans-BAY-850Epigenetic Reader Domaintrans isomer of BAY-850ATAD2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks