2. Epigenetics
  3. Epigenetic Reader Domain
  4. trans-BAY-850

trans-BAY-850 is the trans isomer of BAY-850 (HY-119254). BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.

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trans-BAY-850 Chemical Structure

trans-BAY-850 Chemical Structure

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10 mg USD 160 In-stock
25 mg USD 335 In-stock
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100 mg USD 860 In-stock
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trans-BAY-850 Related Antibodies

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Description

trans-BAY-850 is the trans isomer of BAY-850 (HY-119254). BAY-850 is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM.

Molecular Weight

654.24

Formula

C38H44ClN5O3
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N[C@H](CC1=CC=C(C#N)C=C1)CN[C@@H]2CC[C@@H](N)CC2)C3=CC(C4=CC=C(CN[C@@H](C5=CC=C(C)C=C5)C)O4)=C(OC)C=C3Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (152.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5285 mL 7.6425 mL 15.2849 mL
5 mM 0.3057 mL 1.5285 mL 3.0570 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5285 mL 7.6425 mL 15.2849 mL 38.2123 mL
5 mM 0.3057 mL 1.5285 mL 3.0570 mL 7.6425 mL
10 mM 0.1528 mL 0.7642 mL 1.5285 mL 3.8212 mL
15 mM 0.1019 mL 0.5095 mL 1.0190 mL 2.5475 mL
20 mM 0.0764 mL 0.3821 mL 0.7642 mL 1.9106 mL
25 mM 0.0611 mL 0.3057 mL 0.6114 mL 1.5285 mL
30 mM 0.0509 mL 0.2547 mL 0.5095 mL 1.2737 mL
40 mM 0.0382 mL 0.1911 mL 0.3821 mL 0.9553 mL
50 mM 0.0306 mL 0.1528 mL 0.3057 mL 0.7642 mL
60 mM 0.0255 mL 0.1274 mL 0.2547 mL 0.6369 mL
80 mM 0.0191 mL 0.0955 mL 0.1911 mL 0.4777 mL
100 mM 0.0153 mL 0.0764 mL 0.1528 mL 0.3821 mL
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trans-BAY-850 Related Classifications

Keywords:

trans-BAY-850Epigenetic Reader Domaintrans isomer of BAY-850ATAD2Inhibitorinhibitorinhibit

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HY-119254A
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