1. Peptides
  2. Peptide and Derivatives
  3. Inhibitors and Substrates
  4. [Val4] Angiotensin III

[Val4] Angiotensin III is an angiotension III peptide. [Val4] Angiotensin III is a potent full agonist of q and βarr2 response, with pEC50 values of 8.31 and 8.44, respectively.

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[Val4] Angiotensin III Chemical Structure

[Val4] Angiotensin III Chemical Structure

CAS No. : 100900-28-5

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Based on 1 publication(s) in Google Scholar

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Description

[Val4] Angiotensin III is an angiotension III peptide. [Val4] Angiotensin III is a potent full agonist of q and βarr2 response, with pEC50 values of 8.31 and 8.44, respectively[1].

IC50 & Target

q (G protein), βarr2 (β-arrestin)[1]

Molecular Weight

977.12

Formula

C47H68N12O11

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Arg-Val-Tyr-Val-His-Pro-Phe

Sequence Shortening

RVYVHPF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (51.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0234 mL 5.1171 mL 10.2342 mL
5 mM 0.2047 mL 1.0234 mL 2.0468 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0234 mL 5.1171 mL 10.2342 mL 25.5854 mL
5 mM 0.2047 mL 1.0234 mL 2.0468 mL 5.1171 mL
10 mM 0.1023 mL 0.5117 mL 1.0234 mL 2.5585 mL
15 mM 0.0682 mL 0.3411 mL 0.6823 mL 1.7057 mL
20 mM 0.0512 mL 0.2559 mL 0.5117 mL 1.2793 mL
25 mM 0.0409 mL 0.2047 mL 0.4094 mL 1.0234 mL
30 mM 0.0341 mL 0.1706 mL 0.3411 mL 0.8528 mL
40 mM 0.0256 mL 0.1279 mL 0.2559 mL 0.6396 mL
50 mM 0.0205 mL 0.1023 mL 0.2047 mL 0.5117 mL
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[Val4] Angiotensin III Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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[Val4] Angiotensin III
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HY-P3910
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