2. GPCR/G Protein
  3. CaSR
  4. CaSR antagonist-1

CaSR antagonist-1 is a calcium sensing receptor (CaSR) antagonist with an IC50 value of 50 nM. CaSR antagonist-1 can be used for the research of disorders associated with abnormal bone or mineral homeostasis such as osteoporosis.

For research use only. We do not sell to patients.

CaSR antagonist-1 Chemical Structure

CaSR antagonist-1 Chemical Structure

CAS No. : 1219811-83-2

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CaSR antagonist-1 Related Antibodies

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Description

CaSR antagonist-1 is a calcium sensing receptor (CaSR) antagonist with an IC50 value of 50 nM. CaSR antagonist-1 can be used for the research of disorders associated with abnormal bone or mineral homeostasis such as osteoporosis[1].

IC50 & Target

IC50:50 nM (CaSR)[1].EC50:＞50 μM (hPXR Gene reporter assay)[1].
Molecular Weight

497.58

Formula

C29H24FN3O2S
CAS No.
SMILES

O=C1C(C2=CC(C3=CC=CC=N3)=C(C)S2)=C(C)N=C(N1CCC4=CC=CC=C4)C5=C(O)C(F)=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CaSR antagonist-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CaSR antagonist-11219811-83-2CaSR antagonist1CaSR antagonist 1CaSRCalcium-sensing receptorcalcium sensing receptor (CaSR)osteoporosispregnane X receptor (PXR)Inhibitorinhibitorinhibit

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CaSR antagonist-1
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HY-153258
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