1. Gene
  2. COX5B - cytochrome c oxidase subunit 5B Gene

COX5B - cytochrome c oxidase subunit 5B Gene

Homo sapiens

Also known as COXVB

Gene ID: 1329 | Gene type: protein coding

About COX5B

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:97,646,062-97,648,383 (from NCBI)

This gene has 4 transcripts (splice variants) and 284 orthologues. Broad expression in colon (RPKM 200.2), kidney (RPKM 188.7) and 24 other tissues.

Summary

Cytochrome C oxidase (COX) is the terminal Enzyme of the mitochondrial respiratory chain. It is a multi-subunit Enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain Enzyme. [provided by RefSeq, Jul 2008]

COX5B Products(1)

mRNA Protein Name
NM_001862.3 NP_001853.2 cytochrome c oxidase subunit 5B, mitochondrial precursor

COX5B Protein Structure

COX5B

COX5B: Cytochrome c oxidase subunit Vb (3 - 124)

  • 0
  • 100
  • 129 a.a.
Protein Preferred Names Protein Names

cytochrome c oxidase subunit 5B, mitochondrial

cytochrome c oxidase polypeptide VB, mitochondrial

Recombinant COX5B Proteins

Cat. No. Product Name Accession Purity
HY-P75686 COX5B Protein, Human (His) P10606 (A32-H129) ≥95%

Orthologs Information

Species Symbol Source ID
Canis familiaris COX5B VGNC VGNC:39540
Rattus norvegicus COX5B RGD RGD:620608
Mus musculus COX5B MGD MGI:88475
Felis catus COX5B VGNC VGNC:103730
Others COX5B NCBI