2. Gene
  3. DDX3X - DEAD-box helicase 3 X-linked Gene

DDX3X - DEAD-box helicase 3 X-linked Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DBX; DDX3; HLP2; DDX14; CAP-Rf; MRX102; MRXSSB

Gene ID: 1654 | Gene type: protein coding

About DDX3X

Cytogenetic location: Xp11.4 Genomic coordinates (GRCh38): X:41,333,308-41,364,472 (from NCBI)

This gene has 69 transcripts (splice variants), 283 orthologues, 38 paralogues and is associated with 84 phenotypes. Ubiquitous expression in bone marrow (RPKM 90.6), gall bladder (RPKM 60.1) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

DDX3X Products(4)

mRNA Protein Name
NM_001193416.3 NP_001180345.1 ATP-dependent RNA helicase DDX3X isoform 2
NM_001193417.3 NP_001180346.1 ATP-dependent RNA helicase DDX3X isoform 3
NM_001356.5 NP_001347.3 ATP-dependent RNA helicase DDX3X isoform 1
NM_001363819.1 NP_001350748.1 ATP-dependent RNA helicase DDX3X isoform 4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
10074132 GOA
enables CTPase activity IDA
IDA: Inferred from direct assay
10074132 GOA
enables DNA binding IDA
IDA: Inferred from direct assay
21589879 GOA
enables DNA helicase activity IDA
IDA: Inferred from direct assay
21589879 GOA
enables GTPase activity IDA
IDA: Inferred from direct assay
10074132 GOA
enables RNA binding IDA
IDA: Inferred from direct assay
21589879 GOA
enables RNA helicase activity IDA
IDA: Inferred from direct assay
21589879 GOA
enables RNA stem-loop binding IDA
IDA: Inferred from direct assay
22872150 GOA
enables RNA strand annealing activity IDA
IDA: Inferred from direct assay
27546789 GOA
enables eukaryotic initiation factor 4E binding IDA
IDA: Inferred from direct assay
17667941 GOA
enables gamma-tubulin binding IDA
IDA: Inferred from direct assay
28842590 GOA
enables mRNA 5'-UTR binding IDA
IDA: Inferred from direct assay
22872150 GOA
enables mRNA binding IDA
IDA: Inferred from direct assay
29062139 GOA
enables poly(A) binding IDA
IDA: Inferred from direct assay
18596238 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10074132 GOA
enables protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
23413191 GOA
enables ribonucleoside triphosphate phosphatase activity IDA
IDA: Inferred from direct assay
10074132 GOA
enables ribosomal small subunit binding IDA
IDA: Inferred from direct assay
22323517 GOA
enables signaling adaptor activity IDA
IDA: Inferred from direct assay
23478265 GOA
enables transcription factor binding IDA
IDA: Inferred from direct assay
16818630 GOA
enables translation initiation factor binding IDA
IDA: Inferred from direct assay
22323517 GOA
Biological Process GO Annotation Evidence Reference Source
involved in RNA secondary structure unwinding IDA
IDA: Inferred from direct assay
22872150 GOA
involved in Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
26235985 GOA
involved in cellular response to arsenic-containing substance IDA
IDA: Inferred from direct assay
21883093 GOA
involved in cellular response to osmotic stress IDA
IDA: Inferred from direct assay
21883093 GOA
involved in cellular response to virus IDA
IDA: Inferred from direct assay
31575075 GOA
involved in chromosome segregation IMP
IMP: Inferred from mutant phenotype
21730191 GOA
involved in cytosolic ribosome assembly IMP
IMP: Inferred from mutant phenotype
22323517 GOA
involved in extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: Inferred from mutant phenotype
18846110 GOA
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
18583960 GOA
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
18636090 GOA
involved in intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
16301996 GOA
involved in lipid homeostasis IMP
IMP: Inferred from mutant phenotype
28128295 GOA
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
18846110 GOA
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
16818630 GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
18846110 GOA
involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: Inferred from mutant phenotype
18846110 GOA
involved in negative regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21883093 GOA
involved in negative regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
27736973 GOA
involved in negative regulation of protein-containing complex assembly IDA
IDA: Inferred from direct assay
17667941 GOA
involved in negative regulation of translation IMP
IMP: Inferred from mutant phenotype
17667941 GOA
involved in positive regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
20837705 GOA
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16301996 GOA
involved in positive regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
23413191 GOA
involved in positive regulation of cell growth IMP
IMP: Inferred from mutant phenotype
18628297 GOA
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
16301996 GOA
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
10074132 GOA
involved in positive regulation of interferon-alpha production IDA
IDA: Inferred from direct assay
30341167 GOA
involved in positive regulation of interferon-beta production IDA
IDA: Inferred from direct assay
27980081 GOA
involved in positive regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
30341167 GOA
involved in positive regulation of protein K63-linked ubiquitination IDA
IDA: Inferred from direct assay
27980081 GOA
involved in positive regulation of protein acetylation IMP
IMP: Inferred from mutant phenotype
28128295 GOA
involved in positive regulation of protein autophosphorylation IDA
IDA: Inferred from direct assay
30341167 GOA
involved in positive regulation of protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
23413191 GOA
involved in positive regulation of toll-like receptor 7 signaling pathway IDA
IDA: Inferred from direct assay
30341167 GOA
involved in positive regulation of toll-like receptor 8 signaling pathway IDA
IDA: Inferred from direct assay
30341167 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16818630 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
18583960 GOA
involved in positive regulation of translation IDA
IDA: Inferred from direct assay
18596238 GOA
involved in positive regulation of translation IMP
IMP: Inferred from mutant phenotype
28842590 GOA
involved in positive regulation of translation in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
29062139 GOA
involved in positive regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
20837705 GOA
involved in positive regulation of type I interferon production IDA
IDA: Inferred from direct assay
23478265 GOA
involved in positive regulation of viral genome replication IMP
IMP: Inferred from mutant phenotype
20862261 GOA
involved in protein localization to cytoplasmic stress granule IMP
IMP: Inferred from mutant phenotype
24965446 GOA
involved in response to virus IDA
IDA: Inferred from direct assay
18636090 GOA
involved in stress granule assembly IDA
IDA: Inferred from direct assay
21883093 GOA
involved in translational initiation IMP
IMP: Inferred from mutant phenotype
26100019 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cell leading edge IDA
IDA: Inferred from direct assay
28733330 GOA
located in centrosome IDA
IDA: Inferred from direct assay
28842590 GOA
is active in cytoplasm IDA
IDA: Inferred from direct assay
18636090 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
10329544 GOA
located in cytoplasm IMP
IMP: Inferred from mutant phenotype
10074132 GOA
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
18596238 GOA
part of cytosolic small ribosomal subunit IDA
IDA: Inferred from direct assay
18596238 GOA
part of eukaryotic translation initiation factor 3 complex IDA
IDA: Inferred from direct assay
18628297 GOA
located in nucleus IDA
IDA: Inferred from direct assay
10074132 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
29899501 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX3X Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (204 - 391)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (460 - 536)

  • 0
  • 200
  • 400
  • 600
  • 662 a.a.
Protein Preferred Names Protein Names

ATP-dependent RNA helicase DDX3X

DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked

DDX3X Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
DDX3X O00571 NCAPH Homo sapiens Q15003
Anti Bait CoIP
21730191
Intra
DDX3X O00571 EIF2S1 Homo sapiens P05198
Anti Tag CoIP
18596238
Intra
DDX3X O00571 EIF2S1 Homo sapiens P05198
Anti Tag CoIP
22323517
Intra
DDX3X O00571 EIF2S1 Homo sapiens P05198
Cosedimentation
18596238
Intra
DDX3X O00571 IKBKE Homo sapiens Q14164
Anti Bait CoIP
18636090
Intra
DDX3X O00571 IKBKE Homo sapiens Q14164
Anti Tag CoIP
18636090
Intra
DDX3X O00571 EIF3C Homo sapiens Q99613
Anti Bait CoIP
22323517
Intra
DDX3X O00571 EIF3C Homo sapiens Q99613
Anti Tag CoIP
22323517
Intra
DDX3X O00571 EIF3C Homo sapiens Q99613
Anti Bait CoIP
18628297
Intra
DDX3X O00571 EIF3B Homo sapiens P55884
Anti Bait CoIP
18628297
Intra
DDX3X O00571 EIF3B Homo sapiens P55884
Anti Tag CoIP
18628297
Intra
DDX3X O00571 TARDBP Homo sapiens Q13148
Validated Y2H
32814053
Intra
DDX3X O00571 TARDBP Homo sapiens Q13148
Y2H Array
32814053
Intra
DDX3X O00571 TARDBP Homo sapiens Q13148
Y2H Pooling
32814053
Intra
DDX3X O00571 NXF1 Homo sapiens Q9UBU9
Anti Tag CoIP
18596238
Intra
DDX3X O00571 TFF2 Homo sapiens Q03403
Validated Y2H
32814053
Intra
DDX3X O00571 TFF2 Homo sapiens Q03403
Y2H Array
32814053
Intra
DDX3X O00571 TFF2 Homo sapiens Q03403
Y2H Pooling
32814053
Intra
DDX3X O00571 EIF4G1 Homo sapiens Q04637
Pull Down
22872150
Intra
DDX3X O00571 EIF4G1 Homo sapiens Q04637
IF
22872150
Intra
DDX3X O00571 EIF4G1 Homo sapiens Q04637
Anti Tag CoIP
22872150
Cross
DDX3X O00571 Trpm7 Mus musculus Q923J1
Anti Tag CoIP
24855944
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Anti Tag CoIP
18596238
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
IF
21883093
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Confocal
21883093
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Anti Bait CoIP
21883093
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Pull Down
22872150
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Pull Down
21883093
Intra
DDX3X O00571 PABPC1 Homo sapiens P11940
Confocal
18596238
Intra
DDX3X O00571 RIGI Homo sapiens O95786
Anti Tag CoIP
20127681
Intra
DDX3X O00571 MAVS Homo sapiens Q7Z434
Anti Tag CoIP
20127681
Intra
DDX3X O00571 MAVS Homo sapiens Q7Z434
Confocal
20127681
Cross
DDX3X O00571 L Lymphocytic choriomeningitis virus P14240
Anti Tag CoIP
29261807
Cross
DDX3X O00571 tat Human immunodeficiency virus P04608
IF
23840900
Cross
DDX3X O00571 tat Human immunodeficiency virus P04608
Anti Bait CoIP
23840900
Cross
DDX3X O00571 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566
Confocal
10074132
Cross
DDX3X O00571 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566
NTPase Assay
10074132
Cross
DDX3X O00571 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566
Pull Down
20862261
Cross
DDX3X O00571 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566
Y2H
10074132
Cross
DDX3X O00571 polg_hcvjf Hepatitis C virus Q99IB8
IF
22616990
Cross
DDX3X O00571 polg_hcvjf Hepatitis C virus Q99IB8
Y2H
22616990
Cross
DDX3X O00571 OPG044 Vaccinia virus P68467
Anti Bait CoIP
18636090
Cross
DDX3X O00571 OPG044 Vaccinia virus P68467
IF
18636090
Cross
DDX3X O00571 PB2 Influenza A virus P03427
SLC
23816991
Cross
DDX3X O00571 P26664-PRO_0000037517 Hepatitis C virus P26664-PRO_0000037517
Pull Down
10336476
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type

MRXSSB

Mental Retardation, X-Linked 102, Formerly

Mrx102, Formerly

Intellectual Developmental Disorder, X-Linked Syndromic, Snijders Blok Type

X-Linked Intellectual Disability-Hypotonia-Movement Disorder Syndrome

Mrx102
Corpus Callosum, Agenesis Of, With Facial Anomalies And Robin Sequence

Toriello-Carey Syndrome

Corpus Callosum Agenesis-Blepharophimosis-Robin Sequence Syndrome

Agenesis Of Corpus Callosum With Facial Anomalies And Robin Sequence

Corpus Callosum Agenesis Facial Anomalies Robin Sequence
Rare Genetic Intellectual Disability
Precursor T-Cell Acute Lymphoblastic Leukemia

T-All

Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Precursor T-Cell Acute Lymphocytic Leukemia

Precursor T-Cell Acute Lymphocytic Leukemia/Lymphoma

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Adult T-Cell Lymphoma/Leukemia
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Venezuelan Equine Encephalitis

Venezuelan Equine Fever

Venezuelan Equine Encephalomyelitis

Encephalitis Venezuelan Equine

Encephalomyelitis, Venezuelan Equine

Venezuelan Encephalitis

Disorder Due To Venezuelan Equine Encephalitis Virus

Venezuelan Equine Encephalitis Virus Infection

Venezuelan Equine Encephalomyelitis Virus Disease
Encephalitis

Mumps Encephalitis

Mumps Meningoencephalitis

Herpes Simplex Neuroinvasion

Herpetic Encephalitis

Herpetic Encephalopathy

Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis

Encephalitis Due To Herpesviridae

Encephalitis Due To Herpesvirus

Herpes Encephalitis

Herpesviral Encephalitis

Herpes Simplex Encephalitis

Hsv - [Herpes Simplex Virus] Encephalitis

Herpes Virus Encephalitis

Simian B Disease

Simian B Disorder

Encephalitis Nec

Idiopathic Encephalitis
Hepatitis C

Chronic Hepatitis C

Hepatitis C Infection

Hepatitis Nona Nonb

Nanbh

Viral Hepatitis C

Hepatitis C Chronic

Hepatitis C, Chronic

Chronic Type C Viral Hepatitis

Chronic Hcv - [Hepatitis C Virus] Infection

Hepatitis C Nos

Hepatitis C Infection Nos

Hepatitis C-Related Cirrhosis

Type C Viral Hepatitis

Hep C Nos
Hepatitis

Chronic Hepatitis

Chronic Persistent Hepatitis

Acute Hepatitis

Hepatitis, Chronic

Acute And Subacute Liver Necrosis

Acute/Subac. Necrosis Of Liver

Animal Hepatitis

Hepatitis Chronic

Hepatitis A

Hepatitis, Animal

Hepatitis Due To Toxoplasmosis

Hepatitis In Toxoplasmosis

Toxoplasmal Hepatitis

Chronic Hepatitis, Unspecified

Chronic Active Hepatitis Nec

Other Specified Chronic Hepatitis

Chronic Persistent Hepatitis Nec

Chronic Lobular Hepatitis Nec
Hepatitis C Virus

Hepatitis C Virus, Susceptibility To

Hepatitis C Virus Infection, Response To Therapy Of

Hcv

Hcv, Susceptibility To

Hepatitis C Virus, Resistance To

Hepatitis C Virus, Response To Therapy Of

Resistance To Hepatitis C Virus
Cerebellar Hypoplasia/Atrophy, Epilepsy, And Global Developmental Delay

CHEGDD
Hepatitis B

Chronic Hepatitis B

Hepatitis B Infection

Serum Hepatitis

HBV

Hepatitis B Chronic

Hbv, Susceptibility To

Hepatitis B, Chronic

Chronic Hepatitis B Without Delta Agent

Chronic Hbv - [Hepatitis B Virus] Infection

Hepatitis B Nos

Chronic Type B Viral Hepatitis

Hep B Nos
Immunodeficiency 27a

IMD27A

Autosomal Recessive Ifngr1 Deficiency

Autosomal Recessive Immunodeficiency 27a, Mycobacteriosis

Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency

Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency

Autosomal Recessive Msmd Due To Partial Ifngammar1 Deficiency

Autosomal Recessive Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency

Immunodeficiency 27a, Mycobacteriosis, Autosomal Recessive

Ifngr1 Deficiency, Autosomal Recessive

Immunodeficiency 27a, Mycobacteriosis, Ar

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Ifngammar1 Deficiency

Msmd Due To Complete Ifngammar1 Deficiency

Msmd Due To Complete Interferon Gamma Receptor 1 Deficiency

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interferon Gamma Receptor 1 Deficiency

Familial Disseminated Atypical Mycobacterial Infection

Interferon Gamma, Receptor 1, Deficiency

Immunodeficiency, Type 27a, Mycobacteriosis, Ar

Mycobacterial Disease, Mendelian Susceptibility To
Systemic Epstein-Barr Virus Positive T-Cell Lymphoma Of Childhood

Ebv-Positive T-Cell Lymphoproliferative Disorder Of Childhood

Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma Of Childhood

Systemic Ebv-Positive T-Cell Lymphoma Of Childhood

Systemic Ebv+ T-Cell Lymphoma Of Childhood
Endocervical Adenocarcinoma

Endocervical Carcinoma
Lymphocytic Choriomeningitis

Lcm

Lymphocytic Meningitis

Lymphocytic Choriomeningitis Virus Encephalomyelitis

Lymphocytic Meningoencephalitis

Non-Arthropod Borne Lymphocytic Choriomeningitis

Lcm - [Lymphocytic Choriomeningitis]

Benign Lymphocytic Meningitis

Meningitis Due To Lymphocytic Choriomeningitis Virus
Cervical Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Cervix Uteri

Squamous Cell Carcinoma Of Cervix
Aggressive Nk-Cell Leukemia

Aggressive Nk-Cell Leukaemia

Large Granular Lymphocyte Leukemia, Nk-Cell Type

Natural Killer Cell Leukaemia

Natural Killer Cell Leukemia

Aggressive Nk Cell Leukemia

Ankl

Aggressive Natural Killer Cell Leukemia

Ankcl

Aggressive Nk-Cell Lymphoma

Nk-Cell Lgl Leukemia

Nk-Cell Large Granular Lymphocyte Leukemia

Abnormality Of The Ankles

Aggressive Natural Killer-Cell Leukemia

Leukemia, Large Granular Lymphocytic

Leukemia, Natural Killer Cell Large Granular Lymphocytic
Adult Medulloblastoma

Adult Brain Medulloblastoma

Medulloblastoma, Adult
Encephalopathy, Neonatal Severe, Due To Mecp2 Mutations

Severe Congenital Encephalopathy Due To Mecp2 Mutation

Severe Neonatal-Onset Encephalopathy With Microcephaly

Encephalopathy, Neonatal Severe

Neonatal Severe Encephalopathy Due To Mecp2 Mutations

Mecp2-Related Severe Neonatal Encephalopathy

Methyl-Cytosine Phosphate Guanine Binding Protein 2 Related Severe Neonatal Encephalopathy

Severe Neonatal Encephalopathy Due To Mecp2 Mutations

ENS-MECP2

Encephalopathy, Neonatal, Severe
Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site
Childhood Medulloblastoma

Medulloblastoma, Childhood

Pediatric Medulloblastoma

Medulloblastoma Childhood
High-Grade B-Cell Lymphoma Double-Hit/Triple-Hit

Hgbl-Dh/Th

High Grade B-Cell Lymphoma With Myc And Bcl2 Or Bcl6 Rearrangements

High Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement
Basal Cell Nevus Syndrome

Nevoid Basal Cell Carcinoma Syndrome

Gorlin Syndrome

Nbccs

BCNS

Gorlin-Goltz Syndrome

Multiple Basal Cell Nevi, Odontogenic Keratocysts, And Skeletal Anomalies

Cerebral Gigantism Jaw Cysts

Cramer Niederdellmann Syndrome

Gorlin Syndrome Or Gorlin-Goltz Syndrome

Naevoid Basal Cell Carcinoma Syndrome
Infratentorial Cancer

Infratentorial Neoplasms

Brain Neoplasm, Infratentorial

Malignant Infratentorial Tumors
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03646 DDX3X Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus DDX3X RGD RGD:1564771
Canis familiaris DDX3X VGNC VGNC:54664
Mus musculus DDX3X MGD MGI:103064
Bos taurus DDX3X VGNC VGNC:56526