1. Anti-infection Metabolic Enzyme/Protease
  2. HIV Protease
  3. HIV-1 protease-IN-14

HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity.

For research use only. We do not sell to patients.

HIV-1 protease-IN-14 Chemical Structure

HIV-1 protease-IN-14 Chemical Structure

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Description

HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity[1].

IC50 & Target

Ki: 0.28 nM (WT HIV-1 PR); 56.9 nM (R41T HIV-1 PR)[1]

Molecular Weight

590.73

Formula

C30H42N2O8S

SMILES

O=C(N[C@H]([C@H](O)CN(S(=O)(C1=CC=C(OC(C)C)C=C1)=O)CC(C)C)CC2=CC=CC=C2)O[C@@H]3[C@H]4[C@H](OCC4)OC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HIV-1 protease-IN-14 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HIV-1 protease-IN-14
Cat. No.:
HY-169166
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