mmu-miR-7a-5p antagomir

Cat. No.: HY-RI04133A: Data Sheet Handling Instructions Technical Support

mmu-miR-7a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

For research use only. We do not sell to patients.

RNA, (ACAACAAAAUCACUAGUCUUC) (2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification)

mmu-miR-7a-5p antagomir Chemical Structure

Size	Price	Stock	Quantity
5 nmol	USD 225	Get quote 1-2 weeks 1-2 weeks 1-2 weeks	1-2 weeks
20 nmol	USD 450	Get quote 1-2 weeks 1-2 weeks 1-2 weeks	1-2 weeks

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Based on 1 publication(s) in Google Scholar

Other Forms of mmu-miR-7a-5p antagomir:

mmu-miR-7a-5p inhibitor Get quote

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Description	mmu-miR-7a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Molecular Weight	7621.99
miRBase Accession Number	MI0000641
Mature miRNA Sequence	UGGAAGACUAGUGAUUUUGUUGU
Stem-loop ID	mmu-mir-7a-1
Stem-loop Sequence	UUGGAUGUUGGCCUAGUUCUGUGUGGAAGACUAGUGAUUUUGUUGUUUUUAGAUAACUAAAACGACAACAAAUCACAGUCUGCCAUAUGGCACAGGCCACCUCUACAG
Species	Mouse, Rat, Drosophila melanogaster, Aedes aegypti, Alligator mississippiensis, Anolis carolinensis, Anopheles gambiae, Apis mellifera, Astatotilapia burtoni, Bombyx mori, Branchiostoma belcheri, Branchiostoma floridae, Ciona savignyi, Cricetulus griseus, Culex quinquefasciatus, Daphnia pulex, Dog, Drosophila ananassae, Drosophila erecta, Drosophila grimshawi, Drosophila mojavensis, Drosophila persimilis, Drosophila pseudoobscura, Drosophila sechellia, Drosophila simulans, Drosophila willistoni, Drosophila yakuba, Gadus morhua, Horse, Ictalurus punctatus, Ixodes scapularis, Lytechinus variegatus, Metriaclima zebra, Nasonia longicornis, Nasonia vitripennis, Neolamprologus brichardi, Oreochromis niloticus, Ornithorhynchus anatinus, Pan troglodytes, Patiria miniata, Petromyzon marinus, Pundamilia nyererei, Rhesus monkey, Saccoglossus kowalevskii, Salmo salar, Strongylocentrotus purpuratus, Taeniopygia guttata, Tetraodon nigroviridis, Zebrafish
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (229 KB) Handling Instructions (2659 KB)