2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation Anti-infection Metabolic Enzyme/Protease
  3. Histamine Receptor Bacterial Cytochrome P450
  4. Ranitidine

Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine is a weak inhibitor of CYP2C19 and CYP2C9.

For research use only. We do not sell to patients.

Ranitidine Chemical Structure

Ranitidine Chemical Structure

CAS No. : 66357-35-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Ranitidine:

Ranitidine Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Ranitidine

View All Histamine Receptor Isoform Specific Products:

View All Isoforms
H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine is a weak inhibitor of CYP2C19 and CYP2C9[1][2].

IC50 & Target[1][2]

H2 Receptor

3.3 μM (IC50)

CYP2C19

 

CYP2C9

 

Clinical Trial
Molecular Weight

314.40

Formula

C13H22N4O3S
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=[N+](/C=C(NC)/NCCSCC1=CC=C(CN(C)C)O1)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: ≥97.0%

COA (244 KB)

Handling Instructions (2659 KB)
References
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Ranitidine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ranitidine66357-35-5Histamine ReceptorBacterialCytochrome P450CYPsGastricsecretionH2-receptororallyCYP2C19CYP2C9Inhibitorinhibitorinhibit

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