Search Result

Results for "

1-A-N

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) AAK1 (1) ADC Linker (1) Adrenergic Receptor (1) Amino Acid Derivatives (2) Antibiotic (1) Apoptosis (1) Biochemical Assay Reagents (15) Calcium Channel (1) Caspase (1) CD47 (1) Cytochrome P450 (1) DNA/RNA Synthesis (2) Dopamine Receptor (1) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) E1/E2/E3 Enzyme (1) Endogenous Metabolite (8) Estrogen Receptor/ERR (1) FGFR (1) Fluorescent Dye (2) Formyl Peptide Receptor (FPR) (1) Fungal (1) Galectin (1) Glucosylceramide Synthase (GCS) (1) GlyT (1) Interleukin Related (1) Isotope-Labeled Compounds (3) Ligands for Target Protein for PROTAC (1) Liposome (1) Mitochondrial Metabolism (1) Neurokinin Receptor (1) Nucleoside Antimetabolite/Analog (3) Phosphatase (1) Prostaglandin Receptor (2) PROTAC Linkers (1) PROTACs (1) Ser/Thr Protease (1) TRP Channel (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (3) Endocrinology (2) Infection (2) Inflammation/Immunology (7) Metabolic Disease (5) Neurological Disease (6)
Click Chemistry:	ADC Synthesis (1) Labeling and Fluorescence Imaging (1) PROTAC Synthesis (1) Azide (2) Alkynes (4)
Oligonucleotides:	Nucleosides and their Analogs (3) Cationic Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0222

N,N-Dimethyl-1-naphthylamine	Fluorescent Dye	Others
N,N-Dimethyl-1-naphthylamine is an aromatic amine and a dye. N,N-Dimethyl-1-naphthylamine can be used in nitrate reduction test ^[1] .

HY-150235

Galectin-8N-IN-1	Galectin	Inflammation/Immunology
Galectin-8N-IN-1 (compound 19a) is a potent and selective galectin-8N inhibitor with a K_d value of 1.8 μM. Galectin-8N-IN-1 is a galectin-8N ligand. Galectin-8N-IN-1 can be used in research of immune system ^[1].

HY-159675

*1-A-N*	Liposome	Inflammation/Immunology
1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene ^[1].

HY-E70139

*UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2* EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II	Glucosylceramide Synthase (GCS)	Others
UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2 ( EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II) is a glycosyltransferase ^[1].

HY-N9147

1-Hydroxy-N-methylacridone	Others	Neurological Disease
1-Hydroxy-N-methylacridone is an acridone alkaloid from Boronia lanceolate ^[1].

HY-N10636

*D-lactosyl-β-1,1′ N-stearoyl-D-erythro-sphingosine*	Others	Others
D-lactosyl-β-1,1′ N-stearoyl-D-erythro-sphingosine is a neutral glycolipid ^[1].

HY-169250

TMPRSS13-IN-1	Ser/Thr Protease	Cancer
TMPRSS13-IN-1 (N-0430) is a potent TMPRSS13 inhibitor with a K_i of 25 nM ^[1].

HY-Y1078

DMF-DMA N-Dimethoxymethyl-N,N-dimethylamine	Biochemical Assay Reagents	Others
1,1-Dimethoxy-N,N-dimethylmethanamine (N-Dimethoxymethyl-N,N-dimethylamine) is a biological molecule.

HY-W717623

N,N-Dimethylundecan-1-amine oxide	Biochemical Assay Reagents	Others
N,N-Dimethylundecan-1-amine oxide is an organic building block that may act as a surfactant ^[1].

HY-111845

Estrone-N-O-C1-amido ERα ligand 1	Estrogen Receptor/ERR Ligands for Target Protein for PROTAC	Cancer
Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to *cIAP1* ligand Bestatin via a linker to form SNIPER ^[1].

HY-157429

25N-N1-Nap	5-HT Receptor	Neurological Disease
25N-N1-Nap (compound 16) is a β-arrestin-biased 5-HT2A agonist. 25N-N1-Nap antagonizes phencyclidine induced hyperactivity in Male C57BL/6 J mice ^[1].

HY-E70048

*beta-1,3-N-Acetylgalactosaminyltransferase (LgtD)* Gb4 synthetase	Others	Others
beta-1,3-N-Acetylgalactosaminyltransferase (LgtD) (Gb4 synthetase) expressed by mature/activated B cells ^[1].

HY-140569

N-(PEG1-OH)-N-Boc-PEG2-propargyl	PROTAC Linkers	Cancer
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1]. N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139733

β-N-Acetyl-D-hexosaminidase-IN-1	Others	Others
β-N-Acetyl-D-hexosaminidase-IN-1 is a novel β-N-acetyl-d-hexosaminidase inhibitor with a K_i value of 3.72 μM.

HY-N12302

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine	Others	Others
N1-Dihydrocaffeoyl, N10-caffeoyl spermidine is a natural product that can be isolated from Lycium ruthenicum Murr. ^[1].

HY-W010348

Betaine monohydrate	Biochemical Assay Reagents	Others
1-Carboxy-N,N,N-trimethylmethanaminium hydroxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Y1818

Benzyltrimethylammonium chloride	Biochemical Assay Reagents	Others
N,N,N-trimethyl-1-phenylmethanaminium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-128113

AG-09/1	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense ^[1].

HY-W008630

Decyltrimethylammonium bromide	Biochemical Assay Reagents	Others
N,N,N-Trimethyldecan-1-aminium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Y0120

Tributylmethylammonium chloride Methyltributylammonium chloride	Biochemical Assay Reagents	Others
N,N-Dibutyl-N-methylbutan-1-aminium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-E70049

*beta-1,4-N-Acetylgalactosaminyltransferase (CgtA)* GM2/GD2 synthase	Others	Neurological Disease
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides ^[1].

HY-E70033

*D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)*	Endogenous Metabolite	Metabolic Disease
D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) is a member of CAZy glycoside hydrolase GH112 family, is often used in biochemical studies. D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) catalyses the phosphorolysis of lacto-n-biose and galacto-n-biose, to produce Gal-1-P and the corresponding N-acetyl-D-hexosamine ^[1].

HY-W099930

N,N,N-Trimethylpropan-1-aminium bromide Trimethylpropylammonium bromide	Biochemical Assay Reagents	Others
N,N,N-Trimethylpropan-1-aminium bromide is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor or antimicrobial. Due to its unique chemical properties, N,N,N-Trimethylpropan-1-aminium bromide has applications in various industries such as pharmaceuticals, agrochemicals, and materials science.

HY-147083

SGC-AAK1-1N	AAK1	Cancer
SGC-AAK1-1N is a potent and selective *AAK1* (AP2 associated kinase 1) inhibitor, with an IC₅₀ of 1.8 μM ^[1].

HY-W014536

N,N,N-Trimethyloctan-1-aminium chloride Trimethyl-n-octylammonium Chloride	Biochemical Assay Reagents	Others
N,N,N-Trimethyloctan-1-aminium chloride is a quaternary ammonium salt consisting of a positively charged N,N,N-trimethyloctan-1-aminium cation and a negatively charged chloride anion. The compound is commonly used as a surfactant and emulsifier in a variety of applications including detergents, fabric softeners and personal care products. It can also be used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. Additionally, it has antimicrobial properties and is used as a disinfectant or antiseptic in some products.

HY-124891

1-Phenylpyrrole N-Phenylpyrrole	Others	Others
1-Phenylpyrrole (N-Phenylpyrrole) has dual fluorescent properties. 1-Phenylpyrrole displays a single band in nonpolar solvents and a second red-shifted fluorescent band in polar solvents ^[1].

HY-139006

N-Oleoyl glutamine	TRP Channel	Neurological Disease
N-oleoyl-glutamine is a PM20D1-regulated N-acyl amino acids (NAAs). N-oleoyl-glutamine is a transient receptor potential (TRP) antagonist ^[1].

HY-N10634

*D-Glucosyl-β-1,1′-N-palmitoylsphingosine* C16 Glucosyl(β) Ceramide (d18:1/16:0)	Others	Inflammation/Immunology
D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand possessing immunostimulatory activity ^[1].

HY-150658S

*DMT-2′O-TBDMS-rA(ac)-1-15N* phosphoramidite**	Isotope-Labeled Compounds	Others
DMT-2′O-TBDMS-rA(ac)-1- ¹⁵N phosphoramidite is the ¹⁵N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite[1].

HY-100617A

(RS)-4CPG (RS)-4-Carboxyphenylglycine	Others	Others
(RS)-4CPG ((RS)-4-Carboxyphenylglycine) is a type I metabotropic glutamate receptor antagonist with activity in blocking LTP induction. In mice lacking IP3R1, (RS)-4CPG (500μM) nearly blocked long-term potentiation (LTP) induced by type I metabotropic glutamate receptor activation, with LTP of 117.6±1.7% (n = 8) in IP3R1(-/-) mice and 116.9±1.8% (n = 5) in IP3R1(+/+) mice.

HY-E70051

*alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)* EC 2.4.1.40(Pm1138)	Endogenous Metabolite	Others
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also namely the ABO system transferase with glycosyl transferase activity ^[1].

HY-W002736

N,N'-Di-Boc-1H-pyrazole-1-carboximidamide	Biochemical Assay Reagents	Others
N,N'-Di-Boc-1H-pyrazole-1-carboximidamide (Compound 1) is a biochemical reagent that can be used as a biological material or organic compound for life science related research ^[1].

HY-12726S1

Liproxstatin-1-15N	Isotope-Labeled Compounds	Cancer
Liproxstatin-1- ¹⁵N is the ¹⁵N labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC₅₀=22 nM) ^[1].

HY-115754

S-(N-PhenethylthiocarbaMoyl)-L-cysteine PEITC-Cys	DNA/RNA Synthesis Cytochrome P450	Cancer
S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells ^[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor .

HY-Y0252S4

L-Proline-13C5,15N	Endogenous Metabolite	Others
L-Proline- ¹³C₅,1- ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-110273

N106	Calcium Channel E1/E2/E3 Enzyme	Cardiovascular Disease
N106 is a first-in-class sarcoplasmic reticulum calcium ATPase (SERCA2a) SUMOylation activator. N106 directly activates the SUMO-activating enzyme, E1 ligase. N106 can be used for heart failure research ^[1].

HY-E70136

Endo-β-Galactosidase	Others	Metabolic Disease
Endo-β-Galactosidase catalyzes the hydrolysis of internal β1-4 galactose linkages in unbranched, repeating poly-N-acetyllactosamine ([GlcNAc- (1-3)Gal- (1-4)]_n) structures ^[1].

HY-149777

B3GNT2-IN-1	Others	Others
B3GNT2-IN-1 (compound 8j) is a *β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2)* inhibitor, with an IC₅₀ of 9 nM ^[1].

HY-E70140

*α-1,4-N-Acetylglucosaminyltransferase 4* EC 2.4.1; A4GNT	Antibiotic	Infection
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth ^[1].

HY-P2776

Hexokinase, microorganism	Endogenous Metabolite	Metabolic Disease
Hexokinase (ScHEX1) (EC 2.7.1.1) is a glycolytic enzyme hexokinase that is inhibited by n-acetylglucosamine. Inhibition of Hexokinase (ScHEX1) by n-acetylglucosamine leads to its separation from the mitochondrial outer membrane, resulting in activation of NLRP3 inflammasome ^[1].

HY-E70061

*alpha-1,3-N-Acetylgalactosaminyltransferase (BgtA)*	Others	Others
alpha-1,3-N-Acetylgalactosaminyltransferase (BgtA) is an acetylgalactose aminotransferase, which can be isolated from Helicobacter mustelae, and can specifically recognize Fucα1,2-Gal epitopes ^[1].

HY-100644

Trimethoprim N-oxide Trimethoprim 1-N-oxide	Drug Metabolite	Infection
Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes ^[1].

HY-E70060

beta-1,4-Galactosyltransferase (LgtE) EB4GALT1 (LgtE)	Others	Others
beta-1,4-Galactosyltransferase (LgtE) (EB4GALT1 (LgtE)) catalyzes the reaction involving UDP-galactose and N-acetylglucosamine for the production of galactose beta-1,4-N-acetylglucosamine ^[1].

HY-152325

N1-(N,N-Dimethylaminocarbonyl)-pseudouridine	Nucleoside Antimetabolite/Analog	Others
N1-(N,N-Dimethylaminocarbonyl)-pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc ^[1].

HY-B1449S10

Uridine-13C5 β-Uridine-¹³C₅	Isotope-Labeled Compounds	Cancer
Uridine- ¹³C₅ (β-Uridine- ¹³C₅) is a ¹³C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

HY-W001160

5-Hydroxyindole	Endogenous Metabolite	Others
5-Hydroxyindole, a hydroxylated indole, can be found in a vast array of pharmacologically active agents and natural products. 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells ^[1] .

HY-W014728

N-Methyldopamine hydrochloride	Dopamine Receptor	Cardiovascular Disease Neurological Disease
N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research ^[1] .

HY-W702068

7-Hydroxygranisetron hydrochloride Metabolite D hydrochloride	Biochemical Assay Reagents	Others
7-Hydroxy-1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide (Metabolite D) hydrochloride is a biological molecule.

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Fungal	Cancer
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity ^[1] .

HY-120726

BF844	Others	Others
BF844 mitigate hearing loss associated with USH3 (usher syndrome type III) mutation CLRN1 (clarin-1) ^N48K. BF844 induces CLRN1 ^N48K transportes to the plasma membrane. BF844 shows significantly preserves hearing in vivo ^[1].

Cat. No.	Product Name	Type

HY-D0222

N,N-Dimethyl-1-naphthylamine	Dyes
N,N-Dimethyl-1-naphthylamine is an aromatic amine and a dye. N,N-Dimethyl-1-naphthylamine can be used in nitrate reduction test ^[1] .

Cat. No.	Product Name	Type

HY-W008630

Decyltrimethylammonium bromide	Biochemical Assay Reagents
N,N,N-Trimethyldecan-1-aminium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W002736

N,N'-Di-Boc-1H-pyrazole-1-carboximidamide	Biochemical Assay Reagents
N,N'-Di-Boc-1H-pyrazole-1-carboximidamide (Compound 1) is a biochemical reagent that can be used as a biological material or organic compound for life science related research ^[1].

HY-E70139

*UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2* EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II	Enzyme Substrates
UDP-GalNAc:β-1,3-N-acetylgalactosaminyltransferase 2 ( EC:2.4.1.313; B3GALNT2; β-1,3-N-acetylgalactosaminyltransferase II) is a glycosyltransferase ^[1].

HY-W010348

Betaine monohydrate	Cell Assay Reagents
1-Carboxy-N,N,N-trimethylmethanaminium hydroxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Y1818

Benzyltrimethylammonium chloride	Surfactants
N,N,N-trimethyl-1-phenylmethanaminium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Y0120

Tributylmethylammonium chloride Methyltributylammonium chloride	Biochemical Assay Reagents
N,N-Dibutyl-N-methylbutan-1-aminium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W099930

N,N,N-Trimethylpropan-1-aminium bromide

Trimethylpropylammonium bromide

Biochemical Assay Reagents

N,N,N-Trimethylpropan-1-aminium bromide is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is widely used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. It can also be used as a surfactant, corrosion inhibitor or antimicrobial. Due to its unique chemical properties, N,N,N-Trimethylpropan-1-aminium bromide has applications in various industries such as pharmaceuticals, agrochemicals, and materials science.

HY-W014536

N,N,N-Trimethyloctan-1-aminium chloride

Trimethyl-n-octylammonium Chloride

Biochemical Assay Reagents

N,N,N-Trimethyloctan-1-aminium chloride is a quaternary ammonium salt consisting of a positively charged N,N,N-trimethyloctan-1-aminium cation and a negatively charged chloride anion. The compound is commonly used as a surfactant and emulsifier in a variety of applications including detergents, fabric softeners and personal care products. It can also be used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. Additionally, it has antimicrobial properties and is used as a disinfectant or antiseptic in some products.

HY-E70140

*α-1,4-N-Acetylglucosaminyltransferase 4* EC 2.4.1; A4GNT	Enzyme Substrates
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth ^[1].

HY-E70141

*β-1,3-N-Acetylglucosaminyltransferase 4* EC:2.4.1.149; B3GNT4	Enzyme Substrates
β-1,3-N-Acetylglucosaminyltransferase 4 (EC:2.4.1.149, B3GNT4) is involved in the synthesis of poly-N-acetyllactosamine and has activity for type 2 oligosaccharides ^[1].

HY-138540

1-Dodecylimidazole 1 Publications Verification N-Dodecylimidazole	Cell Assay Reagents
1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity ^[1] .

HY-E70143

Glucosaminyl (N-acetyl) Transferase 2 EC:2.4.1.15; N-Acetylglucosaminyltransferase	Enzyme Substrates
Glucosaminyl (N-acetyl) Transferase 2 (EC:2.4.1.150, GCNT2, GCNT5, NACGT1, N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, N-acetylglucosaminyltransferase, IGNT) is responsible for formation of the blood group I antigen and plays an important role in cancer ^[1].

HY-W551412

β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine

Carbohydrates

β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology ^[1].

HY-158455

FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AA labelled FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AA labelled; G1F with bisecting GlcNAc, 2-AA labelled	Carbohydrates
FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AA labelled (FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AA labelled; G1F with bisecting GlcNAc, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans ^[1].

HY-158456

FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AB labelled FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AB labelled; G1F with bisecting GlcNAc, 2-AB labelled	Carbohydrates
FA2[3]BG1 & FA2[6]BG1 glycan (G1B), 2-AB labelled (FA2[3]BG1 & FA2[6]BG1 glycan N-linked oligosaccharide, 2-AB labelled; G1F with bisecting GlcNAc, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans ^[1].

HY-W127407

Glycerophospho-N-arachidonoyl ethanolamine

Drug Delivery

Glycerophospho-N-Arachidonoyl Ethanolamine is a N-acylated ethanolamines (NAEs). Most NAEs are naturally occurring lipids with diverse biological activities. Different types of NAE can be derived from glycerophosphate-linked precursors through the activity of glycerophosphodiesterase 1 (GDE1). Glycerophosphate-N-Arachidonoyl Ethanolamine is the precursor of Anandamide (AEA), also known as Anandamide. AEA is an endocannabinoid neurotransmitter that binds to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM compared to 46 nM for δ9-THC.

Cat. No.	Product Name	Target	Research Area

HY-13541

ADH-1 5+ Cited Publications	Peptides	Cancer
ADH-1, an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion.

HY-P5349

4N1K peptide	Peptides	Others
4N1K peptide is a biological active peptide. (4N1K-peptide (KRFYVVMWKK), which is derived from thrombospondins has anti-cancer activities in several cancers)

HY-139006

N-Oleoyl glutamine	TRP Channel	Neurological Disease
N-oleoyl-glutamine is a PM20D1-regulated N-acyl amino acids (NAAs). N-oleoyl-glutamine is a transient receptor potential (TRP) antagonist ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P99777

Ontorpacept TTI-621	CD47	Cancer
Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10634

*D-Glucosyl-β-1,1′-N-palmitoylsphingosine* C16 Glucosyl(β) Ceramide (d18:1/16:0)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Others
D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand possessing immunostimulatory activity ^[1].

HY-W001160

5-Hydroxyindole	Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields Indole Alkaloids	Endogenous Metabolite
5-Hydroxyindole, a hydroxylated indole, can be found in a vast array of pharmacologically active agents and natural products. 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells ^[1] .

HY-103332

N-Arachidonylglycine 1 Publications Verification NA-Gly	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	GlyT Endogenous Metabolite
N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC₅₀ = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC₅₀ = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration ^[1] .

HY-W011978

N-Acetyl-L-tryptophan	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to *NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β* and the activation of *caspase-1*. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases ^[1] .

HY-N9147

1-Hydroxy-N-methylacridone	Alkanna cappadocica Source classification Rutaceae Plants	Others
1-Hydroxy-N-methylacridone is an acridone alkaloid from Boronia lanceolate ^[1].

HY-N12302

N1-Dihydrocaffeoyl, N10-caffeoyl spermidine	Structural Classification Source classification Phenols Polyphenols Lycium ruthenicum Murray Plants Solanaceae	Others
N1-Dihydrocaffeoyl, N10-caffeoyl spermidine is a natural product that can be isolated from Lycium ruthenicum Murr. ^[1].

HY-N11454

Lacto-N-neodifucohexaose II LNnDFH II	Structural Classification Polysaccharides Microorganisms Source classification Saccharides	Others
Lacto-N-neodifucohexaose II (Compd 9) is a derivative of key human milk tetrasaccharide ^[1]. Lacto-N-neodifucohexaose II is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Chemical Structure

HY-Y0252S4

L-Proline-13C5,15N
L-Proline- ¹³C₅,1- ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-B1449S10

Uridine-13C5
Uridine- ¹³C₅ (β-Uridine- ¹³C₅) is a ¹³C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.

HY-150658S

*DMT-2′O-TBDMS-rA(ac)-1-15N* phosphoramidite**
DMT-2′O-TBDMS-rA(ac)-1- ¹⁵N phosphoramidite is the ¹⁵N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite[1].

HY-12726S1

Liproxstatin-1-15N
Liproxstatin-1- ¹⁵N is the ¹⁵N labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC₅₀=22 nM) ^[1].

Cat. No.	Product Name		Classification

HY-128676

N-ε-propargyloxycarbonyl-L-lysine hydrochloride 1 Publications Verification H-L-Lys(Poc)-OH hydrochloride		Alkynes Labeling and Fluorescence Imaging
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals ^[1] . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139014

N-ε-propargyloxycarbonyl-L-lysine 1 Publications Verification H-L-Lys(Poc)-OH		Alkynes
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals ^[1] . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140569

N-(PEG1-OH)-N-Boc-PEG2-propargyl		Alkynes PROTAC Synthesis
N-(PEG1-OH)-N-Boc-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs ^[1]. N-(PEG1-OH)-N-Boc-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N11454

Lacto-N-neodifucohexaose II LNnDFH II		Azide
Lacto-N-neodifucohexaose II (Compd 9) is a derivative of key human milk tetrasaccharide ^[1]. Lacto-N-neodifucohexaose II is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151637

Fmoc-N-propargyl-MPBA		Alkynes
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures ^[1]. Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126525

4-N3Pfp-NHS ester		Azide ADC Synthesis
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[1]. 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-112582

N1-Methylpseudouridine 1-Methylpseudouridine; N1-methyl-pseudouridine		Nucleosides and their Analogs
N1-methyl-pseudouridine (1-Methylpseudouridine), a methylpseudouridine, outperforms 5 mC and 5 mC/N1-methyl-pseudouridine in translation. N1-methyl-pseudouridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density ^[1].

HY-159675

*1-A-N*		Cationic Lipids
1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene ^[1].

HY-152325

N1-(N,N-Dimethylaminocarbonyl)-pseudouridine		Nucleosides and their Analogs
N1-(N,N-Dimethylaminocarbonyl)-pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc ^[1].

HY-152657

N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine		Nucleosides and their Analogs
N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc ^[1].

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