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5-Hydroxy saxagliptin-<sup>13</sup>C,d<sub>2</sub>-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Apoptosis (2) Autophagy (1) Bacterial (2) Cannabinoid Receptor (1) COX (3) Dipeptidyl Peptidase (6) Drug Metabolite (14) Endogenous Metabolite (9) FLT3 (1) Fungal (3) Glucocorticoid Receptor (1) Histone Demethylase (1) Isotope-Labeled Compounds (57) Parasite (1) Small Interfering RNA (siRNA) (1) Thrombopoietin Receptor (1) Topoisomerase (1) TRP Channel (1) VD/VDR (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Endocrinology (1) Infection (3) Inflammation/Immunology (5) Metabolic Disease (13) Neurological Disease (5)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

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Screening Libraries

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Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-144199S

*5-Hydroxy* Saxagliptin-13C,d2 hydrochloride**	Isotope-Labeled Compounds	Others
5-Hydroxy Saxagliptin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled 5-Hydroxy Saxagliptin[1].

HY-166882S

*5-Hydroxy* saxagliptin-13C,d2-1 hydrochloride**	Isotope-Labeled Compounds	Others
5-Hydroxy saxagliptin- ¹³C,d₂-1 (hydrochloride) is ¹³C and deuterium labeled 5-Hydroxy saxagliptin (hydrochloride) .

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride BMS-477118-<sup>13sup>C,d<sub>2sub> hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-10285S1

*(rel)-Saxagliptin-13C,d2 TFA* (rel)-BMS-477118-<sup>13sup>C,d<sub>2sub> TFA	Dipeptidyl Peptidase Isotope-Labeled Compounds	Metabolic Disease
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-10285R

Saxagliptin (Standard)	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (Standard) is the analytical standard of Saxagliptin. This product is intended for research and analytical applications. Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-144198S

Saxagliptin-13C,d2 hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled Saxagliptin[1].

HY-16448R

Saxagliptin (hydrochloride) (Standard)	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (hydrochloride) (Standard) is the analytical standard of Saxagliptin (hydrochloride). This product is intended for research and analytical applications. Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-143785S

*rel-Saxagliptin-15N,d2 hydrochloride*	Isotope-Labeled Compounds	Others
rel-Saxagliptin- ¹⁵N,d₂ hydrochloride is the deuterium and ¹⁵N labeled Saxagliptin[1].

HY-W008216S

HMMNI-d3 Hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Infection
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-154754S

Saxagliptin Metabolite-15N,d2 hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin Metabolite- ¹⁵N,d₂ hydrochloride is ¹⁵N and deuterated labeled Saxagliptin Metabolite.

HY-166881S

Saxagliptin-13C,d2-2 hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin- ¹³C,d₂-2 (hydrochloride) is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-10285

*Saxagliptin* 5 Publications Verification BMS-477118	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin (BMS-477118) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin has the peotential for type 2 diabetes mellitus research .

HY-10285A

Saxagliptin hydrate 5 Publications Verification BMS-477118 hydrate	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research .

HY-16448

Saxagliptin hydrochloride 5 Publications Verification BMS-477118 hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Saxagliptin hydrochloride (BMS-477118 hydrochloride) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (K_i = 0.6-1.3 nM) inhibitor. Saxagliptin hydrochloride has the peotential for type 2 diabetes mellitus research .

HY-W008216

HMMNI Hydroxy Dimetridazole	Drug Metabolite	Others
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .

HY-W653916

*8-Hydroxy-2'-deoxyguanosine-13C,15N2* 8-Oxo-2-Deoxyguanosine-<sup>13sup>C,<sup>15sup>N<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
8-Hydroxy-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-32351AS1

Calcifediol-13C5 monohydrate 25-Hydroxy Vitamin D3-<sup>13sup>C<sub>5sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol- ¹³C₅ monohydrate is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-Hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; Hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-Hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-113294S

3-Hydroxykynurenine-13C3,15N 3-Hydroxy-DL-kynurenine-<sup>13sup>C<sub>3sub>,<sup>15sup>N	Isotope-Labeled Compounds	Others
3-Hydroxykynurenine- ¹³C₃, ¹⁵N (3-Hydroxy-DL-kynurenine- ¹³C₃, ¹⁵N)is the ¹³C and ¹⁵N labeled3-Hydroxykynurenine(HY-113294) . 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6** RU 42698-d<sub>6sub>	Isotope-Labeled Compounds	Others
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111975S1

*7'-Hydroxy* ABA-d2** 7'-OH ABA-d<sub>2sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7** 7'-OH ABA-d<sub>7sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8** 8'-OH-ABA-d<sub>8sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2** 8'-OH-ABA-d<sub>2sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5** CGP52421-d<sub>5sub>	Isotope-Labeled Compounds FLT3	Cancer
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C<sub>4sub>	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-169892S

*4-Hydroxy* Nonenal Glutathione-d3** 4-HNE-GSH-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Nonenal Glutathione-d₃ (4-HNE-GSH-d₃) is deuterium labeled 4-Hydroxy Nonenal Glutathione .

HY-W128657S

3-Chloro-2-hydroxypropanoic acid-13C3 2-Hydroxy-3-chloropropionic Acid-<sup>13sup>C<sup>3sup>	Isotope-Labeled Compounds	Others
3-Chloro-2-hydroxypropanoic acid- ¹³C₃ (2-Hydroxy-3-chloropropionic Acid- ¹³C₃) is ¹³C labeled 3-Chloro-2-hydroxypropanoic acid .

HY-115354S

*4-Hydroxy* Alprazolam-d5** 4-Hydroxyalprazolam-d<sub>5sub>; RS-4-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride** GPV-129 D5 Hydrochloride; Lu 40-545 d<sub>5sub>	Isotope-Labeled Compounds	Cardiovascular Disease
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3* N-Vanillyloctadecanamide-d<sub>3sub>	Isotope-Labeled Compounds	Others
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-121385S

Hydroxy Bosentan-d6 Ro 48-5033-d<sub>6sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-121385S1

Hydroxy Bosentan-d4 Ro 48-5033-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-124352S

*2-Nonyl-3-hydroxy-4-quinolone-d4* C9-PQS-d<sub>4sub>	Isotope-Labeled Compounds Bacterial	Others
2-Nonyl-3-hydroxy-4-quinolone-d₄ (C9-PQS-d₄) is deuterium labeled 2-Nonyl-3-hydroxy-4-quinolone. 2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .

HY-130319

9(S)-HEPE	Others	Metabolic Disease
9(S)-HEPE, a hydroxy fatty acid, is a metabolite of Eicosapentaenoic acid .

HY-W015604S

2,3-Diethyl-5-methylpyrazine-13C2 Pyrazine, 2,3-diethyl-5-methyl-<sup>13sup>C<sub>2sub>	Isotope-Labeled Compounds	Others
2,3-Diethyl-5-methylpyrazine- ¹³C₂ is ¹³C labeled 4-Hydroxy-5-methylfuran-3(2H)-one.

HY-118714S

*α-Hydroxy* alprazolam-d5** U 40125-d<sub>5sub>; alpha-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

HY-165678S

*(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5* 10-Hydoxy-cis-12-Octadeceoic Acid-d<sub>5sub>	Isotope-Labeled Compounds	Others
(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d₅ (10-Hydoxy-cis-12-Octadeceoic Acid-d₅) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid .

HY-113038AS

α-Hydroxyglutaric acid-13C5 disodium 2-Hydroxyglutarate-<sup>13sup>C<sub>5sub> disodium; 2-Hydroxyglutaric acid-<sup>13sup>C<sub>5sub> sodium; 2-Hydroxypentanedioic acid-<sup>13sup>C<sub>5sub> disodium	Histone Demethylase Endogenous Metabolite	Cancer
α-Hydroxyglutaric acid- ¹³C₅ (sodium) is the ¹³C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-152040S

Tenuazonic acid-(acetyl-13C2) (mixture of diastereomers) in methanol 3-(Acetyl-<sup>13sup>C<sub>2sub>)-5-((S)-sec-butyl)-4-Hydroxy-1,5-dihydro-2H-pyrrol-2-one	Isotope-Labeled Compounds	Others
Tenuazonic acid-(acetyl- ¹³C₂) (mixture of diastereomers) in methanol (3-(Acetyl- ¹³C₂)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is ¹³C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .

HY-32351AS

Calcifediol-d6 monohydrate 25-Hydroxy Vitamin D3-d<sub>6sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-17461S3

Cortisone-d2 17-Hydroxy-11-dehydrocorticosterone-d<sub>2sub>; Kendall's compound E-d<sub>2sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Endocrinology
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-110189S

Pregnenolone monosulfate sodium-13C2,d2 3β-Hydroxy-5-pregnen-20-one monosulfate (sodium)-<sup>13sup>C<sub>2sub>,d<sub>2sub>	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone monosulfate (sodium)- ¹³C₂,d₂ is the ¹³C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3* Chicory furaneol-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-145461

Hydroxy lenalidomide 5-Hydroxy lenalidomide	Others	Others
Hydroxy lenalidomide (5-Hydroxy lenalidomide) is a metabolite of lenalidomide that is present as a minor component in plasma and excreta, accounting for less than 5% of the total radioactivity, following oral administration of lenalidomide in healthy male subjects.

Cat. No.	Product Name

HY-L913

Tyrosine Focused Covalent Fragment Library

124 compounds

Recently, significant advancements in tyrosine-targeting electrophiles have primarily occurred in the field of protein-protein interactions (PPIs), where cysteine residues are often underrepresented and novel chemistries are needed to address these interfaces. In this context, tyrosines are frequently more accessible compared to more buried binding sites. Moreover, they are commonly found at "hot spots," which are functional epitopes of PPIs, with 12.3% of the residues consisting of tyrosines. This prevalence is likely due to the hydrophobic nature of tyrosine, its ability to participate in aromatic π-interactions, and its capacity for hydrogen bonding. Beyond PPIs, some progress has also been made in covalent tyrosine targeting in other areas where more commonly addressed side chains are lacking. Even though tyrosine has a slightly lower pKa value compared to the protonated lysine side chain (approximately 10 vs. 10.5 for the unprotected amino acid side chains), significantly less progress has been made in the development of tyrosine-targeted covalent ligands compared to lysine. This is likely due to the reduced flexibility of the tyrosine side chain and the greater steric hindrance of its hydroxy group, which makes it more challenging to adopt suitable reaction geometries.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 124 fragment molecules which can target tyrosine residue and can be used for fragment-based covalent drug discovery.

Cat. No.	Product Name	Target	Research Area

HY-P4755

*N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide*	Peptides	Others
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-158104

LPPM-8	Peptides	Others
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N9241

*3-Hydroxy-7-methoxyflavone*	Structural Classification Flavonols Flavonoids Labiatae Source classification Gymnaster koraiensis Plants	Others
3-Hydroxy-7-methoxyflavone (compound 1) is a flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect .

HY-116688

*2-Hydroxy-4-(methylthio)butyric acid*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

HY-N9224

*5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran*	Structural Classification Monophenols Source classification Artemisia dracunculus L. Phenols Plants Compositae	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-N2674

*5-Hydroxy-1-methoxyxanthone* 5-Hydroxy-1-methoxyxanthen-9-one	Structural Classification Flavonoids Hypericum brasiliense Choisy Source classification Hypericaceae Plants Other Flavonoids	Others
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .

HY-135212R

Hydroxy ipronidazole (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-126121R

*2-Hydroxy* Ibuprofen (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	COX
2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

Species:	Human (17) Bovine (2)
Tag:	GFP (3) His (16) Tag Free (1) Strep (5) Myc (1) GST (1) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli Cell-free (1) Sf9 insect cells (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P72228

	HMGCR Protein, Human (His) 3 Hydroxy 3 methylglutaryl CoA reductase; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase; 3 Hydroxymethylglutaryl CoA reductase; 3-Hydroxy-3-methylglutaryl CoA reductase NADPH; ; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase; 3H3M; HMDH_HUMAN; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; Hmgcr; Hydroxymethylglutaryl CoA reductase; LDLCQ3; MGC103269; Red	Human	E. coli
	As a key enzyme in cholesterol biosynthesis, HMGCR protein plays a central role in regulating cellular cholesterol levels. It catalyzes the conversion of HMG-CoA to mevalonate, a key step in the synthesis of cholesterol and other isoprenoids. HMGCR Protein, Human (His) is the recombinant human-derived HMGCR protein, expressed by E. coli , with N-6*His labeled tag.

HY-P73634

	SNAP25 Protein, Human (His) Synaptosomal-associated protein 25; SNAP-25; sup; SNAP	Human	E. coli
	SNAP25 is a key t-SNARE in neurotransmitter release, regulating synaptic function and plasma membrane recycling. It cooperates with CENPF to affect vesicle docking and membrane fusion. SNAP25 Protein, Human (His) is the recombinant human-derived SNAP25 protein, expressed by E. coli , with N-His labeled tag. The total length of SNAP25 Protein, Human (His) is 206 a.a., with molecular weight of ~28 kDa.

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P703566

	ETF1 Protein, Human ERF1; RF1; sup45L1	Human	E. coli
	ETF1 Protein, Human is the recombinant human-derived ETF1, expressed by E. coli , with tag Free labeled tag. The total length of ETF1 Protein, Human is 135 a.a.,

HY-P702942

	ERF1 protein, Human (sf9, GST) ERF1; RF1; sup45L1	Human	Sf9 insect cells
	ERF1 protein, Human (sf9, GST) is the recombinant human-derived ERF1, expressed by Sf9 insect cells , with GST labeled tag. The total length of ERF1 protein, Human (sf9, GST) is 436 a.a.,

HY-P702207

	ADTRP Protein, Human (Cell-Free, His, Myc) Androgen-dependent TFPI-regulating protein; Fatty acid esters of Hydroxy fatty acids hydrolase ADTRP; FAHFA hydrolase ADTRP; C6orf105	Human	E. coli Cell-free
	ADTRP protein exhibits specialized enzymatic activity, specifically hydrolyzing bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), with a notable preference for branched FAHFAs. This unique function distinguishes ADTRP, as it does not hydrolyze other major lipid classes. Moreover, ADTRP regulates endothelial cells, influencing TFPI expression and cell-associated anticoagulant activity, observed in in vitro settings. ADTRP Protein, Human (Cell-Free, His, Myc) is the recombinant human-derived ADTRP protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of ADTRP Protein, Human (Cell-Free, His, Myc) is 230 a.a., with molecular weight of 31.8 kDa.

HY-P71203

	PHS Protein, Human (His) Pterin-4-Alpha-Carbinolamine Dehydratase; PHS; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha; DCoH; Dimerization Cofactor of HNF1; Phenylalanine Hydroxylase-Stimulating Protein; Pterin Carbinolamine Dehy	Human	E. coli
	PHS protein is crucial in tetrahydrobiopterin biosynthesis and has the dual function of hindering the formation of 7-pterin and promoting quinone-BH2. It also acts as a coactivator of HNF1A-dependent transcription, affecting HNF1A dimerization and enhancing its activity. PHS Protein, Human (His) is the recombinant human-derived PHS protein, expressed by E. coli , with N-6*His labeled tag.

HY-P703334

	ABCF3 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human	Human	HEK293
	ABCF3 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCF3, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCF3 Protein, Human (HEK293, His, Strep, Flag) is 708 a.a.,

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P703309

	ABCA6 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family A member 6; ABCA6; Homo sapiens; Human; Translocase	Human	HEK293
	ABCA6 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCA6, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCA6 Protein, Human (HEK293, His, Strep, Flag) is 1616 a.a.,

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Bovine	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Bovine	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q mutation. The total length of bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P703304

	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703305

	ABCB10 Protein, Human (HEK293, Flag, His, N229A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703306

	ABCB10 Protein, Human (HEK293, Flag, His, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703307

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703308

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-144199S

*5-Hydroxy* Saxagliptin-13C,d2 hydrochloride**
5-Hydroxy Saxagliptin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled 5-Hydroxy Saxagliptin[1].

HY-166882S

*5-Hydroxy* saxagliptin-13C,d2-1 hydrochloride**
5-Hydroxy saxagliptin- ¹³C,d₂-1 (hydrochloride) is ¹³C and deuterium labeled 5-Hydroxy saxagliptin (hydrochloride) .

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-10285S1

*(rel)-Saxagliptin-13C,d2 TFA*
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-144198S

Saxagliptin-13C,d2 hydrochloride
Saxagliptin- ¹³C,d₂ (hydrochloride) is the ¹³C- and deuterium labeled Saxagliptin[1].

HY-143785S

*rel-Saxagliptin-15N,d2 hydrochloride*
rel-Saxagliptin- ¹⁵N,d₂ hydrochloride is the deuterium and ¹⁵N labeled Saxagliptin[1].

HY-W008216S

HMMNI-d3
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-154754S

Saxagliptin Metabolite-15N,d2 hydrochloride
Saxagliptin Metabolite- ¹⁵N,d₂ hydrochloride is ¹⁵N and deuterated labeled Saxagliptin Metabolite.

HY-166881S

Saxagliptin-13C,d2-2 hydrochloride
Saxagliptin- ¹³C,d₂-2 (hydrochloride) is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-W653916

*8-Hydroxy-2'-deoxyguanosine-13C,15N2*
8-Hydroxy-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .

HY-32351AS1

Calcifediol-13C5 monohydrate
Calcifediol- ¹³C₅ monohydrate is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-113294S

3-Hydroxykynurenine-13C3,15N
3-Hydroxykynurenine- ¹³C₃, ¹⁵N (3-Hydroxy-DL-kynurenine- ¹³C₃, ¹⁵N)is the ¹³C and ¹⁵N labeled3-Hydroxykynurenine(HY-113294) . 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6**
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-169892S

*4-Hydroxy* Nonenal Glutathione-d3**
4-Hydroxy Nonenal Glutathione-d₃ (4-HNE-GSH-d₃) is deuterium labeled 4-Hydroxy Nonenal Glutathione .

HY-W128657S

3-Chloro-2-hydroxypropanoic acid-13C3
3-Chloro-2-hydroxypropanoic acid- ¹³C₃ (2-Hydroxy-3-chloropropionic Acid- ¹³C₃) is ¹³C labeled 3-Chloro-2-hydroxypropanoic acid .

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-124352S

*2-Nonyl-3-hydroxy-4-quinolone-d4*
2-Nonyl-3-hydroxy-4-quinolone-d₄ (C9-PQS-d₄) is deuterium labeled 2-Nonyl-3-hydroxy-4-quinolone. 2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .

HY-W015604S

2,3-Diethyl-5-methylpyrazine-13C2
2,3-Diethyl-5-methylpyrazine- ¹³C₂ is ¹³C labeled 4-Hydroxy-5-methylfuran-3(2H)-one.

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-165678S

*(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5*
(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d₅ (10-Hydoxy-cis-12-Octadeceoic Acid-d₅) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid .

HY-113038AS

α-Hydroxyglutaric acid-13C5 disodium

α-Hydroxyglutaric acid- ¹³C₅ (sodium) is the ¹³C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-152040S

Tenuazonic acid-(acetyl-13C2) (mixture of diastereomers) in methanol
Tenuazonic acid-(acetyl- ¹³C₂) (mixture of diastereomers) in methanol (3-(Acetyl- ¹³C₂)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is ¹³C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-110189S

Pregnenolone monosulfate sodium-13C2,d2

Pregnenolone monosulfate (sodium)- ¹³C₂,d₂ is the ¹³C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-W021008S

*3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d2*
3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d₂ is deuterated labeled 4-Ethyl-2-methoxyphenol.

HY-136883S

Benzophenone-9-d6
Benzophenone-9-d₆ (Disodium 3,3'-carbonylbis[4-hydroxy-6-methoxybenzenesulphonate]-d₆) is deuterium labeled Benzophenone-9 .

HY-12772S1

*(2R,4S)-Hydroxy* Itraconazole-d8**
(2R,4S)-Hydroxy Itraconazole-d₈ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole[1].

HY-12772S2

*(2R,4S)-Hydroxy* Itraconazole-d5**
(2R,4S)-Hydroxy Itraconazole-d₅ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole[1].

HY-124245S2

*3-Hydroxy* desloratadine-d6**
3-Hydroxy desloratadine-d₆ is deuterated labeled 3-Hydroxy desloratadine (HY-124245). 3-Hydroxy desloratidine is a metabolite of Desloratidine .

HY-135335S

*3'-Hydroxy* Repaglinide-d5**
3'-Hydroxy Repaglinide-d₅ is the deuterium labeled 3'-Hydroxy Repaglinide. 3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide[1].

HY-143976S

*3-Hydroxy* imiquimod-d4**
3-Hydroxy imiquimod-d₄ is the deuterium labeled 3-Hydroxy imiquimod.

HY-143367S

*27-Hydroxy* cholesterol-d6**
27-Hydroxy cholesterol-d₆ is deuterium labeled 27-Hydroxy cholesterol.

HY-144950S

*3-Hydroxy* benzopyrene-d11**
3-Hydroxy benzopyrene-d₁₁is the deuterium labeled3-Hydroxy benzopyrene(HY-144950) . 3-Hydroxy benzopyrene is a metabolite of Benzopyrene (HY-107377) .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81208

	4 Hydroxynonenal Antibody 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; HNE; 4HNE; 4-HNE; (E)-4-Hydroxy-2-nonenal; 2-Nonenal, 4-Hydroxy-, (2E)-; (2E)-4-Hydroxy-2-nonenal; 4-Hydroxy-2(E)-nonenal	WB, ELISA, IHC-P, ICC/IF	Species independent
	4 Hydroxynonenal Antibody is an unconjugated, approximately 0.156 kDa, rabbit-derived, anti-4 Hydroxynonenal polyclonal antibody. 4 Hydroxynonenal Antibody can be used for: WB, ELISA, IHC-P, IF expriments in background without labeling.

HY-P80527

	ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
	ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P81140

	8-OHdG (DNA/RNA Damage) Antibody 8-Hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7,8-Dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG; 2'-Deoxy-8-Hydroxyguanosine;	ELISA, IHC-P, IHC-F, ICC/IF	Species independent
	8-OHdG (DNA/RNA Damage) Antibody is an unconjugated, approximately 0.283 kDa, rabbit-derived, anti-8-OHdG (DNA/RNA Damage) polyclonal antibody. 8-OHdG (DNA/RNA Damage) Antibody can be used for: ELISA, IHC-P, IHC-F, IF expriments in human, background without labeling.

HY-P81196

	HSD3B1 Antibody 3BHS1_HUMAN; 3 beta-Hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-Hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-Hydroxy-5-ene steroid dehydrogenase 1; 3-beta-Hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-Hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A	WB, ICC/IF	Human
	HSD3B1 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-HSD3B1 monoclonal antibody. HSD3B1 Antibody can be used for: WB,ICC/IF expriments in human background without labeling.

HY-P80772

	P Glycoprotein Antibody p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

	MRP2 Antibody ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; Canalicular multidrug resistance protein antibody; Canalicular multispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_HUMAN antibody; Multidrug resistance associated protein 2 antibody; Multidrug resistance-associated protein 2 antibody;	WB, ICC/IF, FC	Human
	MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.

HY-P81197

	HMGCR Antibody 3 Hydroxy 3 methylglutaryl CoA reductase antibody; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 Hydroxymethylglutaryl CoA reductase antibody; 3-Hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody	WB, IP	Human, Mouse
	HMGCR Antibody is an unconjugated, approximately 97 kDa, rabbit-derived, anti-HMGCR monoclonal antibody. HMGCR Antibody can be used for: WB,IP expriments in human, mouse background without labeling.

HY-P81667

	SNAP25 Antibody (YA1412) Synaptosomal-associated protein 25; SNAP-25; super protein; sup; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP	WB, ICC/IF, IP	Human, Mouse, Rat
	SNAP25 Antibody (YA1412) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1412), targeting SNAP25, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). SNAP25 Antibody (YA1412) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

HY-P83598

	ERAB Antibody (YA3343) HSD17B10; ERAB; HADH2; MRPP2; SCHAD; XH98G2; 3-Hydroxyacyl-CoA dehydrogenase type-2; 17-beta-Hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-Hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-Hydroxyacyl-CoA dehydrogenase type II; Endoplasmic	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	ERAB Antibody (YA3343) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3343), targeting ERAB, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). ERAB Antibody (YA3343) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.