1. Search Result
Search Result
Results for "

Antiparasitic Agents

" in MedChemExpress (MCE) Product Catalog:

67

Inhibitors & Agonists

4

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0413
    Fenbendazole
    5 Publications Verification

    Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic Infection Cancer
    Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
    Fenbendazole
  • HY-149960

    Parasite Infection
    Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively .
    Antiparasitic agent-17
  • HY-149078

    Parasite Infection
    Antiparasitic agent-14 is a potemt antiparasitic agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote .
    Antiparasitic agent-14
  • HY-151133

    Parasite Infection
    Antiparasitic agent-9 (compound 47) is an orally active and potent antiparasitic agent. Antiparasitic agent-9 shows antiparasitic activity against the human parasite .
    Antiparasitic agent-9
  • HY-126295

    Parasite Infection
    Anti-parasitic agent 3 is an anti-parasitic agent which active against agent resistant parasites.
    Anti-parasitic agent 3
  • HY-151433

    Parasite Infection
    Antiparasitic agent-10 (Compound 94) is an anti-parasitic agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .
    Antiparasitic agent-10
  • HY-157028

    Others Infection
    Antiparasitic agent-19 (compound 40) is a compound with broad-spectrum antiparasitic activity. Antiparasitic agent-19 has minimal toxicity against Trypanosoma brucei, Leishmania Infantum, and Trypanosoma cruzi .
    Antiparasitic agent-19
  • HY-147806

    Parasite Infection
    Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity .
    Antiparasitic agent-8
  • HY-157466

    Parasite Infection
    Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC50 of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability .
    Antiparasitic agent-21
  • HY-149722

    Parasite Infection
    Antiparasitic agent-20 (Compound 1p) is a parasite inhibitor with broad antiparasitic activity. Antiparasitic agent-20 has inhibitory effects on T. brucei and T. cruzi with EC50 values of 0.09 μM and 14.1 μM respectively .
    Antiparasitic agent-20
  • HY-B0413R

    Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic Infection
    Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
    Fenbendazole (Standard)
  • HY-146044

    Parasite Infection
    Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM) .
    Antiparasitic agent-6
  • HY-146043

    Parasite Infection
    Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM) .
    Antiparasitic agent-5
  • HY-146045

    Parasite Infection
    Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC50 = 10.61 μM) .
    Antiparasitic agent-7
  • HY-149079

    Parasite Necroptosis Infection
    Antiparasitic agent-15, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-15 has IC50s of 0.9 μM and 0.64 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-15 has IC50s of 42.2 μM and 9.58 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-15 induces parasite cell death through necrosis induction. Antiparasitic agent-15 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .
    Antiparasitic agent-15
  • HY-149080

    Parasite Necroptosis Infection
    Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC50s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC50s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .
    Antiparasitic agent-16
  • HY-101590

    L 16726

    Parasite Infection
    Symetine is an antiparasitic and antispirochete agent.
    Symetine
  • HY-B0945
    Nitromide
    1 Publications Verification

    3,5-Dinitrobenzamide

    Parasite Infection
    Nitromide is an anti-parasitic agent.
    Nitromide
  • HY-146042

    Parasite Infection
    Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM) .
    Antiparasitic agent-4
  • HY-146041

    Parasite Infection
    Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM) .
    Antiparasitic agent-2
  • HY-139587

    ML-878

    Parasite Infection
    Umifoxolaner is an anti-parasitic agent (veterinary).
    Umifoxolaner
  • HY-158379

    Parasite Infection
    Antiparasitic agent-22 (Compound 24) is a pan antiparasitic agent, that inhibits T. Brucei, L. infantum, L. tropica promastigotes (IC50 of 2.41, 5.95, 8.98 μM), L. infantum amastigotes (IC50 of 8.18 μM) and P. falciparum W2 strain (IC50 of 0.155 μM). Antiparasitic agent-22 exhibits low cytotoxicity against THP1, with CC50 of 64.16 μM .
    Antiparasitic agent-22
  • HY-18716

    Bacterial Parasite Infection
    Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.
    Dextrorotation nimorazole phosphate ester
  • HY-B1194

    (±)-Tetramisole hydrochloride; DL-Tetramisole hydrochloride; R-829

    Parasite Phosphatase Antibiotic Infection
    Tetramisole hydrochloride inhibits alkaline phosphatase and is a highly pure antiparasitic agent.
    Tetramisole hydrochloride
  • HY-164052

    Parasite Infection
    Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .
    Antiparasitic agent-23
  • HY-155281

    Parasite Infection
    Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC50=0.4 μM), T. cruzi (EC50=0.21 μM), and L. donovani (EC50=0.26 μM). Antiparasitic agent-18 has potent antiprotozoal activity .
    Antiparasitic agent-18
  • HY-109077

    BAY-1272858

    GABA Receptor Parasite Infection Neurological Disease
    Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent .
    Tigolaner
  • HY-B0263S

    2-(4-Thiazolyl)benzimidazole-d4

    Mitochondrial Metabolism Parasite Others
    Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].
    Thiabendazole-d4
  • HY-17598S

    Isotope-Labeled Compounds Parasite Infection
    Rafoxanide 13C6 is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].
    Rafoxanide-13C6
  • HY-N7227

    Glutathione S-transferase Parasite Infection Cancer
    Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .
    Anonaine
  • HY-155087

    Parasite Infection Cancer
    Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities .
    Anticancer agent 140
  • HY-109077S

    Isotope-Labeled Compounds GABA Receptor Parasite Infection Neurological Disease
    Tigolaner-d4 is deuterium labeled Tigolaner. Tigolaner is a GABA antagonist that regulates chloride channel. Tigolaner is an antiparasitic agent[1].
    Tigolaner-d4
  • HY-15308

    Abamectin B1a

    Parasite Antibiotic Infection
    Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a
  • HY-122975

    Benzoyl metronidazole

    Bacterial Parasite Infection
    Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .
    Metronidazole Benzoate
  • HY-118495

    Parasite Infection
    Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .
    Cardol diene
  • HY-117375

    Parasite Infection
    Brotianide is a potent anti-parasitic agent. Brotianide can be used to study liver fluke and gastric fluke infestations .
    Brotianide
  • HY-B1194R

    Parasite Phosphatase Antibiotic Infection
    Tetramisole (hydrochloride) (Standard) is the analytical standard of Tetramisole (hydrochloride). This product is intended for research and analytical applications. Tetramisole hydrochloride inhibits alkaline phosphatase and is a highly pure antiparasitic agent.
    Tetramisole hydrochloride (Standard)
  • HY-146747

    Fungal Parasite Infection Inflammation/Immunology
    Antifungal agent 26, a Pradimicin A derivative, shows antifungal, antiviral, and antiparasitic activities through binding to d-mannose (Man)-containing glycans of pathogenic species .
    Antifungal agent 26
  • HY-125729

    Parasite SARS-CoV Infection
    Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .
    Ivermectin B1b
  • HY-129130

    Canthin-6-one 3-oxide

    Parasite Infection
    Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active antiparasitic agent with limited activity .
    Canthin-6-one N-oxide
  • HY-122382

    NF-602

    Parasite Bacterial Infection
    Levofuraltadone (NF-602) is an antibacterial and antiparasitic agent. Levofuraltadone has anti-trypanosomiasis activity and can be used in the study of human african trypanosomiasis as well as bacterial infections .
    Levofuraltadone
  • HY-14932
    Pafuramidine
    1 Publications Verification

    DB289

    Parasite Antibiotic Infection
    Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria .
    Pafuramidine
  • HY-122975R

    Benzoyl metronidazole (Standard)

    Bacterial Parasite Infection
    Metronidazole Benzoate (Standard) is the analytical standard of Metronidazole Benzoate. This product is intended for research and analytical applications. Metronidazole Benzoate, derives from a metronidazole and a benzoic acid, has a role as an antibacterial, antimicrobial, antiparasitic, and antitrichomonal agent .
    Metronidazole Benzoate (Standard)
  • HY-15308R

    Parasite Antibiotic Infection
    Avermectin B1a (Standard) is the analytical standard of Avermectin B1a. This product is intended for research and analytical applications. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.
    Avermectin B1a (Standard)
  • HY-14932A

    DB289 maleate

    Parasite Antibiotic Infection
    Pafuramidine (maleate) (DB289 (maleate)) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine (maleate) (DB289 (maleate)) is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria .
    Pafuramidine maleate
  • HY-146487

    Bacterial Parasite Infection
    Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .
    Anti-infective agent 1
  • HY-146489

    Bacterial Parasite Infection
    Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .
    Anti-infective agent 3
  • HY-17532

    Parasite Infection
    Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium .
    Haloxon
  • HY-146488

    Parasite Bacterial Infection
    Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL .
    Anti-infective agent 2
  • HY-158776

    Parasite Infection
    SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM .
    SLU-10482

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: