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Results for "

Endocrine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (2) Acyltransferase (1) Akt (4) AMPK (2) Androgen Receptor (6) Apoptosis (13) Autophagy (5) Bacterial (2) Biochemical Assay Reagents (3) Btk (2) Calcium Channel (1) Caspase (2) Complement System (2) CRFR (2) DNA/RNA Synthesis (5) Endogenous Metabolite (23) Epigenetic Reader Domain (3) ERK (4) Estrogen Receptor/ERR (8) Ferroptosis (1) Fluorescent Dye (1) Fungal (6) IGF-1R (2) Isotope-Labeled Compounds (9) Keap1-Nrf2 (2) Mitochondrial Metabolism (2) mTOR (1) Neuropeptide Y Receptor (3) p38 MAPK (2) PI3K (2) Potassium Channel (1) Progesterone Receptor (1) Prostaglandin Receptor (1) PROTAC Linkers (2) Pyroptosis (2) RAR/RXR (3) Ras (1) Reactive Oxygen Species (3) RET (1) Secretin Receptor (1) Succinate Dehydrogenase (2) TGF-β Receptor (2) Topoisomerase (1) VD/VDR (7)
By Research Areas:	Cancer (24) Cardiovascular Disease (12) Endocrinology (47) Infection (12) Inflammation/Immunology (20) Metabolic Disease (26) Neurological Disease (28)
Oligonucleotides:	Antioxidants (1)

107

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-42068

(-)-Aspartic acid (R)-Aspartic acid; D-(-)-Aspartic acid	Pyroptosis	Neurological Disease
(-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .

HY-P1723

Spexin 1 Publications Verification Neuropeptide Q	Neuropeptide Y Receptor	Neurological Disease
Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin peptide contains numerous aromatic amino acids and is probably amidated .

HY-131122S

4-Nonylphenol-D5 4-n-Nonylphenol-2,3,5,6-d4,OD	Estrogen Receptor/ERR	Others
4-Nonylphenol-d₅ is the deuterium labeled 4-Nonylphenol. 4-Nonylphenol, a major degradation product of Nonylphenol ethoxylates (NPEOs), is a persistent organic pollutant with endocrine-disrupting properties and exerts estrogenic activity[1].

HY-W013935

Bisphenol B	Endogenous Metabolite	Endocrinology
Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .

HY-P1298A

Sauvagine TFA	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine TFA, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine TFA is effective at releasing ACTH from rat pituitary cells. Sauvagine TFA possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-B0316

Avobenzone	Estrogen Receptor/ERR Apoptosis	Others
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist .

HY-122399

Luprostiol	Others	Endocrinology
Luprostiol is a prostaglandin analog. Luprostiol can be used to stimulate endocrine changes in animals .

HY-P4060

Pancreatic polypeptide	Neuropeptide Y Receptor	Metabolic Disease Endocrinology
Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion .

HY-P1298

Sauvagine	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-42068R

(-)-Aspartic acid (Standard)	Pyroptosis	Neurological Disease
(-)-Aspartic acid (Standard) is the analytical standard of (-)-Aspartic acid. This product is intended for research and analytical applications. (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .

HY-W013935R

Bisphenol B (Standard)	Endogenous Metabolite	Endocrinology
Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .

HY-B0316R

Avobenzone (Standard)	Estrogen Receptor/ERR Apoptosis	Others
Avobenzone (Standard) is the analytical standard of Avobenzone. This product is intended for research and analytical applications. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist .

HY-122697

ML418	Potassium Channel	Cardiovascular Disease Neurological Disease Endocrinology
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker. ML418 inhibits Kir7.1 with an IC₅₀ value of 0.31 μM. ML418 can be used for the research of neurological, cardiovascular, endocrine and muscle disorders.

HY-160168

BTK-IN-31	Btk	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
BTK-IN-31 (Compound 2) is a selective, non-covalently reversible, and blood-brain barrier (BBB) permeable Btk inhibitor. BTK-IN-31 has research potential in immune disorders, cancer, cardiovascular disease, viral infections, inflammation, metabolic/endocrine dysfunction, and neurological disorders .

HY-118091

LY191704	5 alpha Reductase	Endocrinology
LY191704, as a benzoquinolinone, is a potent, nonsteroidal, noncompetitive and selective human type I 5α-reductase inhibitor. LY191704 is a racemic mixture of the compounds LY300502 and LY300503. LY191704 may be useful in the research of human endocrine disorders associated with overproduction of dihydrotestosterone (DHT) by 5α-reductase type 1 .

HY-160548

mTOR inhibitor-18	mTOR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
mTOR inhibitor-18 (Example 106) is a mTOR inhibitor. mTOR inhibitor-18 can be used for mTOR related research, such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders .

HY-B1866

Linuron	Androgen Receptor	Endocrinology
Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a K_i of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor .

HY-151595

Menin-MLL inhibitor-22	Epigenetic Reader Domain	Cancer
Menin-MLL inhibitor-22 (compound C20) is an orally active inhibitor of the interaction between menin and mixed lineage leukemia (MLL) (IC₅₀=7 nM). Menin-MLL inhibitor-22 binds menin protein and inhibits cancer cell growth (MV4 cells, IC₅₀=0.3 μM). Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) .

HY-B1866R

Linuron (Standard)	Androgen Receptor	Endocrinology
Linuron (Standard) is the analytical standard of Linuron. This product is intended for research and analytical applications. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a Ki of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor .

HY-107916

Thyrotropin 1 Publications Verification TSH; Pretiron	Others	Metabolic Disease Endocrinology
Thyrotropin is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .

HY-P1345

TLQP-21	Complement System	Neurological Disease Endocrinology
TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC₅₀: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca ²⁺. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions .

HY-P1345A

TLQP-21 TFA 1 Publications Verification	Complement System	Neurological Disease Endocrinology
TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC₅₀: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca ²⁺. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions .

HY-17587

4-Methylbenzylidene camphor 1 Publications Verification 4-MBC; Enzacamene	Apoptosis PI3K Akt ERK	Metabolic Disease
4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .

HY-B2058

Triticonazole	Fungal	Infection
Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .

HY-106445

Ciamexon BM 41332	Others	Inflammation/Immunology
Ciamexon is selective immunosuppressive agent. Ciamexon can be used to study endocrine ophthalmopathies and diabetes mellitus .

HY-17587R

4-Methylbenzylidene camphor (Standard)	Apoptosis PI3K Akt ERK	Metabolic Disease
4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .

HY-119384

Promegestone R-5020; Surgestone	Progesterone Receptor	Endocrinology Cancer
Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research .

HY-B2058R

Triticonazole (Standard)	Fungal	Infection
Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .

HY-N7106

Dimethyl phthalate	Biochemical Assay Reagents	Others
Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins .

HY-133620

7-Oxodehydroabietic acid	Others	Infection
7-Oxodehydroabietic acid is a diterpene resin acid isolated from the roots of the pine Pinus densiflora. 7-Oxodehydroabietic acid play a defensive role against herbivorous insects via insect endocrine-disrupting activity .

HY-137043

9-Keto Travoprost Fluprostenol Prostaglandin E2	Prostaglandin Receptor	Endocrinology
9-Keto Travoprost is a derivative of Fluprostenol (HY-108560). 9-Keto Travoprost is an EP receptor agonist. 9-Keto Travoprost can be used in endocrine-related research .

HY-P1784

Secretin, canine	Secretin Receptor	Endocrinology
Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway .

HY-156794

Enzomenib	Others	Cancer
Enzomenib is an inhibitor of the menin protein encoded by the multiple endocrine neoplasia (MEN) gene. Enzomenib can block the binding of the menin protein to mixed lineage leukemia (MLL) fusion proteins and can be used in the study of hematological malignancies .

HY-W013816

Dipentyl phthalate	AMPK Akt	Metabolic Disease
Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant .

HY-106365

Rofleponide	Others	Endocrinology
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models .

HY-137630

Sp-8-pCPT-2'-O-Me-cAMPS	Ras	Metabolic Disease
Sp-8-pCPT-2'-O-Me-cAMPS is an activator of EPAC. Sp-8-pCPT-2'-O-Me-cAMPS can be used in endocrine metabolism related research .

HY-W040270

Amino-PEG10-amine	PROTAC Linkers	Cancer
Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

HY-P2491

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-106938

Eldacimibe WAY-ACA 147	Acyltransferase	Cardiovascular Disease Metabolic Disease
Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) .

HY-N7106S1

Dimethyl phthalate-d6	Isotope-Labeled Compounds	Others
Dimethyl phthalate-d₆ is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].

HY-B1838

Asulam	Others	Others
Asulam is a herbicide with control activity against wild oats. Asulam can be used for bulb production in spinach, tulips, daffodils and lilies. Maximum residue limits (MRLs) for Asulam were evaluated in spinach. The review of Asulam took into account its endocrine disrupting properties .

HY-N7106S

Dimethyl phthalate (Ring-d4)	Isotope-Labeled Compounds	Others
Dimethyl phthalate (Ring-d₄) is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].

HY-130411

Amino-PEG11-amine	PROTAC Linkers	Cancer
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer .

HY-P3041

Chromostatin (bovine)	Calcium Channel	Endocrinology
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID₅₀ of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine .

HY-32351

Calcifediol Maximum Cited Publications 8 Publications Verification 25-hydroxy Vitamin D3	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351A

Calcifediol monohydrate Maximum Cited Publications 8 Publications Verification 25-hydroxy Vitamin D3 monohydrate	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-N7106R

Dimethyl phthalate (Standard)	Biochemical Assay Reagents	Others
Dimethyl phthalate (Standard) is the analytical standard of Dimethyl phthalate. This product is intended for research and analytical applications. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins .

HY-Y0284

Diethyl phthalate	Others	Endocrinology
Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments .

HY-32351S

Calcifediol-d3 25-hydroxy Vitamin D3-d₃	VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-19464

Org 43553	Others	Endocrinology
Org 43553 is an orally active and low molecular weight (LMW) luteinizing hormone receptor (LH-R) agonist. Org 43553 shows agonistic activity to human LH and FSH receptors with EC₅₀ values of 3.7 and 110 nM, respectively. Org 43553 can be used for the research of endocrine .

Cat. No.	Product Name

HY-L047

Endocrinology Compound Library

937 compounds

The endocrine system is a chemical messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. Hormones are chemicals that serve to communicate between organs and tissues for physiological regulation and behavioral activities. Hormones affect distant cells by binding to specific receptor proteins in the target cell, resulting in a change in cell function.

The endocrine system is concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Irregulated hormone release, inappropriate response to signaling or lack of a gland can lead to endocrine disease.

MCE offers a unique collection of 937 endocrinology related compounds targeting varieties of hormone receptors such as thyroid hormone receptor, TSH receptor, GNRH receptor, adrenergic receptor, etc. MCE Endocrinology Compound Library is a useful tool for the discovery of endocrinology drugs.

HY-L078

Gut Microbial Metabolite Library

509 compounds

Accumulating evidence has revealed that intestinal microbiota play an important role in human health and disease, including cardiovascular diseases, inflammatory bowel disease, diabetes, obesity, cancer, and depression, etc. Changes in the composition of gut microbiota associated with disease, referred to as dysbiosis, have been linked to pathologies. Indeed, the gut microbiome functions like an endocrine organ, generating bioactive metabolites which play important roles in human metabolism, health, and disease. Gut microbiome has become a novel therapeutic target for many diseases. Analysis and identification of gut microbial metabolite will contribute to the development of therapeutic methods.

In order to meet the need of gut microbiome research, MCE carefully selected a unique collection of 509 gut microbial metabolites. MCE gut microbial metabolite library is a powerful tool for gut microbiome research and gut microbiome -related drug discovery.

HY-L168

Extracellular Vesicles (EVs) Compound Library

438 compounds

Extracellular vesicles (EVs) are small membrane binding structures that are released from cells into the surrounding environment and play a crucial role in mediating and regulating intercellular communication related to physiological and pathological processes. EVs are lipid membrane vesicles composed of proteins, lipids, and nucleic acids. EVs can be divided into several types based on their source, such as extracellular vesicles, microcapsules, and apoptotic vesicles. The size range of exosomes is 30-150nm, which are endocrine in multi vesicular endosomes (MVEs); microvesicles (50-1000nm) are secreted directly through extracellular interactions, thereby releasing plasma membrane vesicles. In contrast, apoptotic bodies are usually larger, ranging in size from 1 to 5 μ m. This is generated during programmed cell death. EV plays a crucial role in transmitting information between cells and influencing the behavior and function of receptor cells.

MCE designs a unique collection of 438 small molecules related to extracellular vesicles (EVs). It is a good tool to be used for research on metabolize, cancer and other diseases.

Cat. No.	Product Name	Type

HY-W011103

Diheptyl phthalate

Biochemical Assay Reagents

Diheptyl phthalate is a class of phthalates consisting of two heptyl (C7) chains attached to a phthalic acid backbone. This compound is commonly used as a plasticizer in various polymer materials such as PVC to increase flexibility and durability. It can also be used as a lubricant, solvent or additive in various industrial applications such as coatings, adhesives and sealants. However, Diheptyl phthalate has been identified as an environmental pollutant and health hazard due to its potential for endocrine disruption and toxicity.

Cat. No.	Product Name	Target	Research Area

HY-P4058

Calcitonin gene-related peptide free acid CGRP free acid	Peptides	Neurological Disease
Calcitonin gene-related peptide (CGRP) free acid is a neuropeptide. Calcitonin gene-related peptide can be used for the research of nociception, ingestive behaviour and modulation of the endocrine systems .

HY-P1723

Spexin 1 Publications Verification Neuropeptide Q	Neuropeptide Y Receptor	Neurological Disease
Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin peptide contains numerous aromatic amino acids and is probably amidated .

HY-P1298A

Sauvagine TFA	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine TFA, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine TFA is effective at releasing ACTH from rat pituitary cells. Sauvagine TFA possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-P1345A

TLQP-21 TFA 1 Publications Verification	Complement System	Neurological Disease Endocrinology
TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC₅₀: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca ²⁺. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions .

HY-P4060

Pancreatic polypeptide	Neuropeptide Y Receptor	Metabolic Disease Endocrinology
Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion .

HY-P1298

Sauvagine	CRFR	Cardiovascular Disease Neurological Disease Endocrinology
Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is a mammalian CRF agonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, the cardiovascular system and endocrine glands .

HY-P3633

Locustatachykinin II Lom-TK II	Peptides	Neurological Disease
Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .

HY-P5806

Ergtoxin-1 ErgTx1	Peptides	Neurological Disease
Ergtoxin-1 is a potassium channel blocker. Ergtoxin-1 is isolated from the venom of the Mexican scorpion Centruroides noxius. Ergtoxin 1 can block ERG-K ⁺ channels in nerve, heart and endocrine cells .

HY-P1345

TLQP-21	Complement System	Neurological Disease Endocrinology
TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC₅₀: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca ²⁺. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions .

HY-P1784

Secretin, canine	Secretin Receptor	Endocrinology
Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway .

HY-P2491

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P3826

Chromogranin A (324-337), human	Peptides	Neurological Disease
Chromogranin A (324-337), human is a peptide fragment of chromogranin A, it can be isolated from human ileal carcinoid tumor. Chromogranin A is a soluble glycoprotein stored with hormones and neuropeptides in secretory granules of most (neuro)endocrine cells and neurons, and it is also a plasma marker of neuroendocrine tumors .

HY-P3041

Chromostatin (bovine)	Calcium Channel	Endocrinology
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID₅₀ of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine .

HY-P2595

SKF 103784	Peptides	Cardiovascular Disease
SKF 103784 is an vasopressin antagonist with activity against vasopressin. SKF 103784 inhibits the physiological response caused by antidiuretic and is therefore used to study biological processes related to water and salt balance. SKF 103784 can also be used to explore pathological mechanisms related to cardiovascular diseases and endocrine dysfunction .

HY-P4750

Acetyl-(D-Arg2)-GRF (1-29) amide (human)	Peptides	Endocrinology
Acetyl-(D-Arg2)-GRF (1-29) amide (human) is an antagonist of growth hormone releasing factor (GRF). Acetyl-(D-Arg2)-GRF (1-29) amide (human) inhibits the release of growth hormone (GH) and can be used for endocrine research .

HY-P2703

Peptide YY (pig)	Neuropeptide Y Receptor	Metabolic Disease Endocrinology
Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of the Y2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system .

HY-P1803

Protein Kinase C Peptide Substrate PKCε; PRKCE ; Peptide Epsilon	Peptides	Neurological Disease Inflammation/Immunology Endocrinology
Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .

HY-P1777

IGF-I (24-41) Insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-P1777A

IGF-I (24-41) (TFA) Insulin-like Growth Factor I (24-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

HY-P10413

SHBG(141–161)	Androgen Receptor	Metabolic Disease Endocrinology
SHBG 141-161 is a GPRC6A receptor agonist. SHBG 141-161 mimics the action of GPRC6A endogenous agonist uncarboxylated osteocalcin by binding to GPRC6A and promoting downstream signaling to increase testosterone and insulin secretion. SHBG 141-161 also reduces the affinity of GPRC6A to GDP protein by binding to the outer cell domain of GPRC6A thus affecting the dynamics of signal transduction. SHBG 141-161 can be used to study GPRC6A in energy metabolism and endocrine regulation .

HY-P10446

TAT-PiET-PROTAC	Epigenetic Reader Domain	Cancer
TAT-PiET-PROTAC is a proteolysis-targeting chimera (PROTAC)-modified TAT-PiET (HY-P10445). TAT-PiET is a cell-penetrating peptide targeting the extra-terminal (ET) domain of BRD4. TAT-PiET-PROTAC can disrupt the interaction between the breast cancer oncogene BRD4/JMJD6 and inhibit the growth of breast cancer cells. TAT-PiET-PROTAC also resists the endocrine resistance of ERα-positive breast cancer cells and is a potential inhibitor of breast cancer .

HY-P3206

Serum thymic factor Thymulin; Thymic factor	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

HY-P10445

TAT-PiET	Epigenetic Reader Domain	Cancer
TAT-PiET is a cell-penetrating peptide targeting the extra-terminal (ET) domain of BRD4 that disrupts the BRD4/JMJD6 interaction. BRD4/JMJD6 is a protein complex that is critical for oncogene expression and breast cancer, and TAT-PiET inhibits BRD4/JMJD6 target gene expression and breast cancer cell growth. TAT-PiET also resists endocrine resistance in ERα-positive breast cancer cells and is a potential inhibitor of breast cancer .

HY-P10336

Serpinin	Peptides	Neurological Disease Endocrinology
Serpinin is an agonist of the protease inhibitor Nexin-1 (PN-1). Serpinin upregulates the expression of PN-1 through the cAMP-PKA-Sp1 signaling pathway, promoting granule biogenesis in endocrine cells. Serpinin is used in research related to the regulation of secretory function . Serpinin is a selective agonist for β-adrenergic receptors. Serpinin interacts with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, which regulates myocardial systolic and diastolic function. pGlu-serpinin upregulates Bcl2 mRNA transcription and exerts neuroprotective effects .

HY-P3206A

Serum thymic factor acetate Thymulin acetate; Thymic factor acetate	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-42068

(-)-Aspartic acid (R)-Aspartic acid; D-(-)-Aspartic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Pyroptosis
(-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .

HY-W013935

Bisphenol B	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .

HY-N7106

Dimethyl phthalate	Structural Classification Natural Products Microorganisms other families Animals Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Biochemical Assay Reagents
Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins .

HY-32351

Calcifediol Maximum Cited Publications 8 Publications Verification 25-hydroxy Vitamin D3	Structural Classification Natural Products Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351A

Calcifediol monohydrate Maximum Cited Publications 8 Publications Verification 25-hydroxy Vitamin D3 monohydrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-18260

Bisphenol A 5+ Cited Publications	Structural Classification Classification of Application Fields Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .

HY-42068R

(-)-Aspartic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Pyroptosis
(-)-Aspartic acid (Standard) is the analytical standard of (-)-Aspartic acid. This product is intended for research and analytical applications. (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system .

HY-W013935R

Bisphenol B (Standard)	Structural Classification Source classification Phenols Polyphenols Endogenous metabolite	Endogenous Metabolite
Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .

HY-N7106R

Dimethyl phthalate (Standard)	Structural Classification Natural Products Microorganisms other families Animals Source classification Plants	Biochemical Assay Reagents
Dimethyl phthalate (Standard) is the analytical standard of Dimethyl phthalate. This product is intended for research and analytical applications. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins .

HY-32351AR

Calcifediol monohydrate (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	VD/VDR Endogenous Metabolite
Calcifediol monohydrate (Standard) is the analytical standard of Calcifediol (monohydrate). This product is intended for research and analytical applications. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351R

Calcifediol (Standard)	Structural Classification Natural Products Microorganisms Other disease Source classification Disease markers Endogenous metabolite	VD/VDR Endogenous Metabolite
Calcifediol (Standard) is the analytical standard of Calcifediol. This product is intended for research and analytical applications. Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-18260R

Bisphenol A (Standard) 5+ Cited Publications	Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite
Bisphenol A (Standard) is the analytical standard of Bisphenol A. This product is intended for research and analytical applications. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .

HY-N6714

Alternariol	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	Topoisomerase Androgen Receptor Estrogen Receptor/ERR Apoptosis
Alternariol is an orally ingested mycotoxin produced by Alternaria, capable of inhibiting the activity of topoisomerase I and II (topoisomerase I, topoisomerase II). Alternariol has weak estrogenic (Estrogen Receptor/ERR) and androgen/antiandrogen (Androgen Receptor) effects. Alternariol can induce apoptosis, trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects .

HY-N0568

Madecassoside Asiaticoside A	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Tagetes lucida Cav. Umbelliferae Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase
Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB ^[5][6], exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity . Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.

HY-N0568R

Madecassoside (Standard)	Triterpenes Structural Classification Terpenoids Source classification Tagetes lucida Cav. Umbelliferae Plants Endogenous metabolite	Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase
Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.

HY-B1941

4-tert-Octylphenol	Monophenols Neurological Disease Classification of Application Fields Source classification Phenols Endogenous metabolite Disease Research Fields Endocrinology	Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

HY-B1941R

4-tert-Octylphenol (Standard)	Monophenols Source classification Phenols Endogenous metabolite	Endogenous Metabolite Apoptosis DNA/RNA Synthesis
4-tert-Octylphenol (Standard) is the analytical standard of 4-tert-Octylphenol. This product is intended for research and analytical applications. 4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .

Cat. No.	Compare	Product Name	Species	Source

HY-P702542

	RET Protein, Mouse (HEK293, His) CDHF12MTC1; CDHR16; EC 2.7.10; Hirschsprung disease 1; Hirschsprung disease); MEN2A; MEN2B; multiple Endocrine neoplasia and medullary thyroid carcinoma 1; ret proto-oncogene; RET transforming sequence; Ret	Mouse	HEK293
	RET protein is an important receptor tyrosine protein kinase that drives a variety of cellular processes such as proliferation, migration, and differentiation when bound to GDNF ligand. It coordinates organogenesis, shapes the enteric nervous system and promotes kidney development. RET Protein, Mouse (HEK293, His) is the recombinant mouse-derived RET protein, expressed by HEK293 , with C-6*His labeled tag and F174S mutation. The total length of RET Protein, Mouse (HEK293, His) is 609 a.a.

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Cat. No.	Product Name	Chemical Structure

HY-131122S

4-Nonylphenol-D5
4-Nonylphenol-d₅ is the deuterium labeled 4-Nonylphenol. 4-Nonylphenol, a major degradation product of Nonylphenol ethoxylates (NPEOs), is a persistent organic pollutant with endocrine-disrupting properties and exerts estrogenic activity[1].

HY-N7106S

Dimethyl phthalate (Ring-d4)
Dimethyl phthalate (Ring-d₄) is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].

HY-32351S

Calcifediol-d3
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-18260S1

Bisphenol A-d6

Bisphenol A-d₆ is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].

HY-B1805S

Triclocarban-d4

Triclocarban-d₄ is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes[1][2][3].

HY-N7106S1

Dimethyl phthalate-d6
Dimethyl phthalate-d₆ is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].

HY-B0316S

Avobenzone-13C,d3
Avobenzone- ¹³C,d₃ is the ¹³C- and deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2].

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351AS1

Calcifediol-13C5 monohydrate
Calcifediol- ¹³C₅ monohydrate is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-W654077

Bisphenol AF-d4
Bisphenol AF-d₄ is the isotope labelled analog of Bisphenol AF (HY-W013782). Bisphenol AF is a full agonist for the estrogen receptor. Bisphenol AF acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor Era. Bisphenol AF-d₄ can be used for the research of endocrinology and cancer .

HY-107372S4

Uridine triphosphate-15N2 dilithium

Uridine triphosphate- ¹⁵N₂ (UTP- ¹⁵N₂ dilithium; Uridine 5'-triphosphate- ¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-107372S3

Uridine triphosphate-d13 dilithium

Uridine triphosphate-d₁₃ (UTP-d₁₃ dilithium; Uridine 5'-triphosphate-d₁₃) dilithium is deuterium labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-18260S

Bisphenol A-d16

Bisphenol A-d₁₆ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S4

Bisphenol A-d4

Bisphenol A-d₄ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-18260S6

Bisphenol A-d14

Bisphenol A-d₁₄ is a deuterium labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .

HY-107372S2

Uridine triphosphate-13C9 dilithium

Uridine triphosphate- ¹³C₉ (UTP- ¹³C₉ dilithium; Uridine 5'-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-18260S3

Bisphenol A-d8

Bisphenol A-d₈ is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].

HY-18260S5

Bisphenol A-d4-1

Bisphenol A-d₄-1 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].

HY-A0067S

Oxybenzone-d5

Oxybenzone-d₅ is the deuterium labeled Oxybenzone[1]. Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[2][3][4].

Cat. No.	Product Name		Classification

HY-B1066

Butylhydroxyanisole 5 Publications Verification Butylated hydroxyanisole; BHA; E320		Antioxidants
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .

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