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Results for "

Influenza virus-IN-1

" in MedChemExpress (MCE) Product Catalog:

36

Inhibitors & Agonists

2

Peptides

1

Inhibitory Antibodies

7

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131179
    Influenza A virus-IN-1

    		Influenza Virus Infection
    Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA .
    Influenza A virus-IN-1
  • HY-N2216
    Polygalasaponin XXXI

    OnjisaponIN F

    		 Influenza Virus Infection
    Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection .
    Polygalasaponin XXXI
  • HY-145586
    Onradivir

    ZSP1273

    		 Influenza Virus Infection
    Onradivir is a potent anti-influenza virus agent .
    Onradivir
  • HY-P99699
    Lesofavumab

    MHAB5553A; RG70026

    		 Influenza Virus Infection
    Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .
    Lesofavumab
  • HY-126136
    ML303

    		Influenza Virus Infection
    ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1 .
    ML303
  • HY-143492
    Influenza virus-IN-1

    		Influenza Virus Inflammation/Immunology
    Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities .
    Influenza virus-IN-1
  • HY-145586A
    Onradivir monohydrate

    ZSP1273 monohydrate

    		 Influenza Virus Infection
    Onradivir monohydrate is a potent anti-influenza virus agent .
    Onradivir monohydrate
  • HY-156288
    Anti-Influenza agent 5

    		Influenza Virus Infection
    Anti-Influenza agent 5 (Compound IIB-2), chalcone-like derivative, is an influenza nuclear export inhibitor. Anti-Influenza agent 5 has inhibitory effects on oseltamivir-resistant strains. Anti-Influenza agent 5 can impede virus proliferation by blocking the export of influenza virus nucleoprotein .
    Anti-Influenza agent 5
  • HY-143493
    Influenza virus-IN-2

    		Influenza Virus Inflammation/Immunology
    Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities .
    Influenza virus-IN-2
  • HY-155110
    Antiviral agent 34

    		Influenza Virus Infection
    Antiviral agent 34 is a potent and orally active antiviral agent against influenza A and B subtypes with an EC50 value of 0.8 nM for H1N1 proliferation. Antiviral agent 34 derivatives inhibited influenza virus proliferation by targeting influenza virus RNA-dependent RNA polymerase. Antiviral agent 34 can be used for influenza virus research .
    Antiviral agent 34
  • HY-P0289
    CEF3

    		Influenza Virus Infection
    CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.
    CEF3
  • HY-122261
    Spiroamantadine

    DU-34569 maleate

    		 Others Infection
    Spiroamantadine (DU-34569 maleate) is a compound related to Amantadine (HY-B0402) with anti-influenza virus activity .
    Spiroamantadine
  • HY-137660
    pppApG

    		Others Infection
    pppApG is a starting product of both vRNA (viral RNA) and cRNA (complementary RNA) synthesis. pppApG can be used for influenza virus research .
    pppApG
  • HY-13318S
    Oseltamivir acid-d3
    Maximum Cited Publications
    56 Publications Verification

    GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3

    		 Influenza Virus Infection
    Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].
    Oseltamivir acid-d3
  • HY-147654
    PROTAC Hemagglutinin Degrader-1

    		PROTACs Influenza Virus Infection
    PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity .
    PROTAC Hemagglutinin Degrader-1
  • HY-P0313
    CEF6

    		Influenza Virus Infection
    CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.
    CEF6
  • HY-W013794
    Salcomine

    N,N′-Bis(salicylidene)ethylenediamINocobalt(II)

    		 Others Infection
    Salcomine (N,N’-Bis(salicylidene)ethylenediaminocobalt II) is a carrier of O2 and oxidation catalysts. Salcomine has anti-influenza virus activity .
    Salcomine
  • HY-128965
    N-Glycolylneuraminic acid

    NeuGc; GcNeu

    		 Influenza Virus Endogenous Metabolite Inflammation/Immunology
    N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs) .
    N-Glycolylneuraminic acid
  • HY-156048
    Trifluoromethyl-tubercidin

    TFMT

    		 Influenza Virus Infection
    Trifluoromethyl-tubercidin (TFMT) is a 2'-O-ribose methyltransferase 1 (MTr1) inhibitor through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication .
    Trifluoromethyl-tubercidin
  • HY-161983
    Neuraminidase-IN-22

    		Influenza Virus Infection
    Neuraminidase-IN-22 (compound 3e) is a potent, selective and orally active neuraminidase inhibitor with an IC50 value of 0.03 µM. Neuraminidase shows cytotoxicity and anti-influenza A virus activity .
    Neuraminidase-IN-22
  • HY-131069A
    MBX2329

    		Influenza Virus Infection
    MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains .
    MBX2329
  • HY-134608
    Cobalt protoporphyrin IX

    Co-PPIX

    		 Reactive Oxygen Species Influenza Virus Infection
    Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .
    Cobalt protoporphyrin IX
  • HY-N0224A
    Goitrin

    (S)-GoitrIN; L-5-VINyl-2-thiooxazolidone

    		 Influenza Virus Metabolic Disease
    Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
    Goitrin
  • HY-128965R
    N-Glycolylneuraminic acid (Standard)

    NeuGc (Standard); GcNeu (Standard)

    		 Influenza Virus Endogenous Metabolite Inflammation/Immunology
    N-Glycolylneuraminic acid (Standard) is the analytical standard of N-Glycolylneuraminic acid. This product is intended for research and analytical applications. N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs) .
    N-Glycolylneuraminic acid (Standard)
  • HY-N2264
    Wulignan A1

    		Influenza Virus Infection
    Wulignan A1 is isolated from the stems of Schisandra henryi. Wulignan A1 exhibits anti-influenza virus H1N1 and H1N1-TR (a Tamiflu agent resistant virus strain) activities .
    Wulignan A1
  • HY-10964
    Vadimezan
    40+ Cited Publications

    DMXAA; ASA-404

    		 STING IFNAR Influenza Virus Infection Cancer
    Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines. Vadimezan has anti-influenza virus H1N1-PR8 activities.
    Vadimezan
  • HY-161902
    MI-1904

    		Ser/Thr Protease Influenza Virus SARS-CoV Infection
    MI-1904 is the inhibitor for matriptase/TMPRSS2, that exhibits antiviral activity against influenza virus H1N1 and H9N2. MI-1904 blocks the cleavage of glycoproteins on the viral surface, prevents the virus from binding to host cell receptors, and thus inhibits the entry and replication of the virus .
    MI-1904
  • HY-107201
    β-Cyclodextrin
    5+ Cited Publications

    Betadex

    		 Influenza Virus Infection
    β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of agents. β-Cyclodextrin has anti-influenza virus H1N1 activities.
    β-Cyclodextrin
  • HY-107801
    Inosine pranobex
    1 Publications Verification

    Imunovir; Delimmun; GroprINosIN

    		 Interleukin Related HSV HIV HPV Infection Inflammation/Immunology
    Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .
    Inosine pranobex
  • HY-B0532
    Trifluoperazine

    		Dopamine Receptor Adrenergic Receptor P-glycoprotein CaMK Influenza Virus Autophagy Neurological Disease
    Trifluoperazine, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine is a potent α1-adrenergic receptor antagonist. Trifluoperazine is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine can be used for the research of schizophrenia. Trifluoperazine acts as a reversible inhibitor of influenza virus morphogenesis .
    Trifluoperazine
  • HY-B0532A
    Trifluoperazine dihydrochloride
    5+ Cited Publications

    		 Dopamine Receptor Adrenergic Receptor CaMK P-glycoprotein Influenza Virus Autophagy Neurological Disease Cancer
    Trifluoperazine dihydrochloride, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dihydrochloride is a potent α1-adrenergic receptor antagonist. Trifluoperazine dihydrochloride is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dihydrochloride is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dihydrochloride can be used for the research of schizophrenia. Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis .
    Trifluoperazine dihydrochloride
  • HY-162701
    Antiviral agent 58

    		SARS-CoV Influenza Virus RSV HSV Infection
    Antiviral agent 58 (Compound J1) is an orally active antiviral agent with broad-spectrum antiviral activity against enveloped viruses, including influenza A virus (IAV), respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), human coronavirus OC43 (HCoV-OC43), herpes simplex virus type 1 (HSV-1), and HSV-2 .
    Antiviral agent 58
  • HY-107801R
    Inosine pranobex (Standard)

    		Interleukin Related HSV HIV HPV Infection Inflammation/Immunology
    Inosine pranobex (Standard) is the analytical standard of Inosine pranobex. This product is intended for research and analytical applications. Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus .
    Inosine pranobex (Standard)
  • HY-B0532B
    Trifluoperazine dimaleate

    		Dopamine Receptor Adrenergic Receptor P-glycoprotein CaMK Influenza Virus Autophagy Infection Neurological Disease Cancer
    Trifluoperazine dimaleate, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dimaleate is a potent α1-adrenergic receptor antagonist. Trifluoperazine dimaleate is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dimaleate is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dimaleate can be used for the research of schizophrenia. Trifluoperazine dimaleate acts as a reversible inhibitor of influenza virus morphogenesis .
    Trifluoperazine dimaleate
  • HY-125798
    2,3-Dehydro-2-deoxy-N-acetylneuraminic acid
    2 Publications Verification

    Neu5Ac2en; DANA

    		 Influenza Virus Infection
    N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
    2,3-Dehydro-2-deoxy-N-acetylneuraminic acid
  • HY-163670
    TLR7 agonist 21

    		Toll-like Receptor (TLR) Infection
    TLR7 agonist 21 (Compound 27B) is a selective agonist for Toll-like receptor 7(TLR7), with an EC50 of 17.53 nM (for human TLR7) and 41.7 nM (for mouse TLR7). TLR7 agonist 21 stimulates the secretion of pro-inflammatory cytokines, such as IL-6, TNF-α, IFN-α1, and IL-4. TLR7 agonist 21 acts as a vaccine adjuvant, increases levels of IgG and IgA, and protects the mouse from influenza virus infections .
    TLR7 agonist 21

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