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Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria .
Diethylphosphate-d10-1 is the deuterium labeled Diethyl phosphate. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin (HY-N0005) hybridize to exert neuroprotective effects .
Diethyl succinate- 13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Diethyl succinate-d4 is the deuterium labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
Diethyl phosphate (Standard) is the analytical standard of Diethyl phosphate. This product is intended for research and analytical applications. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling .
Diethyl terephthalate (Terephthalic acid) is a monomer in the synthesis of polyethylene terephthalate (PET) material. Diethyl terephthalate is usually used as a substrate for isolating PET-degrading strains .
Mefenpyr-diethyl (Standard) is the analytical standard of Mefenpyr-diethyl. This product is intended for research and analytical applications. Mefenpyr-diethyl is an herbicide safener. Mefenpyr-diethyl enhances plant tolerance to herbicides by inducing the expression of antioxidant enzymes such as GST. Mefenpyr-diethyl protects crops against herbicide injury .
Glutamic acid diethyl ester is a glutamate antagonist with potential biological activity. Glutamic acid diethyl ester is used in biochemical research to explore the mechanism of action of glutamate. Glutamic acid diethyl ester can also be used as a precursor for the synthesis of other compounds and has certain industrial application value. Glutamic acid diethyl ester shows certain application potential in compound development .
Mefenpyr-diethyl is an herbicide safener. Mefenpyr-diethyl enhances plant tolerance to herbicides by inducing the expression of antioxidant enzymes such as GST. Mefenpyr-diethyl protects crops against herbicide injury .
Diethyl D-(-)-tartrate (D-(-)-Tartaric acid diethyl ester) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate. This product is intended for research and analytical applications. Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments .
Diethyl succinate (Standard) is the analytical standard of Diethyl succinate. This product is intended for research and analytical applications. Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments .
Diethyl-Lodoxamide is a highly potent GPR35 agonist with potential to inhibit inflammatory bowel disease. Diethyl-Lodoxamide activates GPR35 in humans, mice and rats, showing similar EC50 values. Diethyl-Lodoxamide can alleviate the clinical symptoms of DSS-induced inflammatory bowel disease in mouse models, and the effect is better than the traditional drug 5-ASA. The pharmaceutical properties of Diethyl-Lodoxamide have been optimized to better meet the requirements of drug design .
Diethyl butylmalonate-d9 is the deuterium labeled Diethyl butylmalonate[1]. Diethyl butylmalonate exhibits toxicity to T. pyriformis, with a log(IGC50-1) of 0.557[2].
Diethyl 6-bromohexylphosphonate is a short linker featuring a bromide and a diethyl phosphonate. The bromide is a good leaving group which can be easily displaced by nucleophiles like alcohols, amines or thiols, while the diethyl phosphonate may be hydrolyzed to allow for esterification.
3,3'-Diethyl-9-methylthiacarbocyanine iodide is a cyanine dye, also a tau aggregation inhibitor, with an IC50 value of 0.28 μM for tau. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can cause misfunction of the microtubule cytoskeleton. 3,3'-Diethyl-9-methylthiacarbocyanine iodide can be used for researching Alzheimer’s disease .
Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Diethyl decanedioate (Standard) is the analytical standard of Diethyl decanedioate. This product is intended for research and analytical applications. Diethyl decanedioate is an organic compound commonly used as a raw material for flavors and food additives. It can be used to make fruit and mint flavors, and is widely used in some food processing and cosmetic production. In addition, this compound is also used as a reagent and intermediate in some organic synthesis reactions.
(2R,3R)-Diethyl 2,3-dihydroxysuccinate (Diethyl tartrate) is utilized in food industry as a flavoring agent and acidity regulator and for this purpose is also used in wines .
1,3-Diethyl 2-oxopropanedioate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Diethylene glycol diethyl ether is an electrolyte solvent for a non-aqueous lithium-air cell. Diethylene glycol diethyl ether can facilitate the reversible reduction and oxidation processes at the porous carbon electrode without a catalyst .
Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
Glutathione diethyl ester is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
Diethyl (cyanomethyl)phosphonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
N,N-Diethyl-p-phenylenediamine Sulfate (Standard) is the analytical standard of N,N-Diethyl-p-phenylenediamine Sulfate. This product is intended for research and analytical applications. N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
Diethyl decanedioate is an organic compound commonly used as a raw material for flavors and food additives. It can be used to make fruit and mint flavors, and is widely used in some food processing and cosmetic production. In addition, this compound is also used as a reagent and intermediate in some organic synthesis reactions.
Diethyl bipy55'DC is an inhibitor of collagen proline 4-hydroxylases (CP4Hs) with antifibrotic and anti-metastatic activities. Diethyl bipy55'DC can inhibit CP4H activity in cultured cells at concentrations that do not cause iron deficiency .
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
Diethyl acetal-PEG4-amine is a PEG reagent containing an amino (NH2) group and a terminal diethyl acetal protecting group, which can be deprotected to form the free aldehyde. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release .
iethyl pyimDC is a collagen prolyl 4-hydroxylase (CP4H1) inhibitor inhibitor with the IC50 of 2.6μM. Diethyl pyimDC can be used for study of antifibrotic and antimetastatic .
Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG3-phosphonic acid diethyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
2’-Deoxy-N2,N2-diethyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
BODIPY aminoacetaldehyde diethyl acetal is a stable precursor to BODIPY-aminoacetaldehyde and can be converted into BODIPY-aminoacetaldehyde under acidic conditions. BODIPY-aminoacetaldehyde is a fluorescent substrate for aldehyde dehydrogenase (ALDH) .
Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a ferrochelatase inhibitor that blocks heme synthesis. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate induces Mallory Denk bodies (MDB) formation. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can be used in the fields of iron metabolism, oxidative stress, and liver-related diseases .
DL-Glyceraldehyde Diethyl Acetal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
L-Mannose,6-deoxy,diethyl dithioacetal is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is a pyridine derivative that can be synthesized by the reaction of benzaldehyde, ethyl acetoacetate and NH4HCO3 .
N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM [1]sup>[2]sup>[3]sup>[4].
Glutathione oxidized- 13C4, 15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .
Cladribine- 13C5, 15N2 (2-Chloro-2′-deoxyadenosine- 13C5, 15N2) is 13C and 15N labeled Cladribine. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
Thymidine- 13C10, 15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling .
Diethyl D-(-)-tartrate (D-(-)-Tartaric acid diethyl ester) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
(2R,3R)-Diethyl 2,3-dihydroxysuccinate (Diethyl tartrate) is utilized in food industry as a flavoring agent and acidity regulator and for this purpose is also used in wines .
1,3-Diethyl 2-oxopropanedioate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Diethylene glycol diethyl ether is an electrolyte solvent for a non-aqueous lithium-air cell. Diethylene glycol diethyl ether can facilitate the reversible reduction and oxidation processes at the porous carbon electrode without a catalyst .
Diethyl (cyanomethyl)phosphonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Diethyl decanedioate (Standard) is the analytical standard of Diethyl decanedioate. This product is intended for research and analytical applications. Diethyl decanedioate is an organic compound commonly used as a raw material for flavors and food additives. It can be used to make fruit and mint flavors, and is widely used in some food processing and cosmetic production. In addition, this compound is also used as a reagent and intermediate in some organic synthesis reactions.
N,N-Diethyl-p-phenylenediamine Sulfate (Standard) is the analytical standard of N,N-Diethyl-p-phenylenediamine Sulfate. This product is intended for research and analytical applications. N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
Diethyl decanedioate is an organic compound commonly used as a raw material for flavors and food additives. It can be used to make fruit and mint flavors, and is widely used in some food processing and cosmetic production. In addition, this compound is also used as a reagent and intermediate in some organic synthesis reactions.
N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
DL-Glyceraldehyde Diethyl Acetal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
L-Mannose,6-deoxy,diethyl dithioacetal is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is a pyridine derivative that can be synthesized by the reaction of benzaldehyde, ethyl acetoacetate and NH4HCO3 .
N,N-Diethyl-N-methylethanaminium tetrafluoroborate is a quaternary ammonium compound belonging to the class of alkylammonium salts. This compound is commonly used as a phase transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. Additionally, it is used as an electrolyte in electrochemical devices and as a surfactant in detergent formulations. Its unique chemical properties make it an important ingredient in a variety of industrial applications, including pharmaceuticals, agrochemicals, and materials science.
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
Glutathione diethyl ester is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin (HY-N0005) hybridize to exert neuroprotective effects .
Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release .
Diethyl phosphate (Standard) is the analytical standard of Diethyl phosphate. This product is intended for research and analytical applications. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Diethyl succinate (Standard) is the analytical standard of Diethyl succinate. This product is intended for research and analytical applications. Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM [1]sup>[2]sup>[3]sup>[4].
SNAP25 is a key t-SNARE in neurotransmitter release, regulating synaptic function and plasma membrane recycling. It cooperates with CENPF to affect vesicle docking and membrane fusion. SNAP25 Protein, Human (His) is the recombinant human-derived SNAP25 protein, expressed by E. coli , with N-His labeled tag.
The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag.
ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.
ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1
ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.
The ABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. ABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is the recombinant bovine-derived ABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-StrepII labeled tag.
Diethylphosphate-d10-1 is the deuterium labeled Diethyl phosphate. Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
Diethyl succinate- 13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Diethyl succinate-d4 is the deuterium labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
Diethyl butylmalonate-d9 is the deuterium labeled Diethyl butylmalonate[1]. Diethyl butylmalonate exhibits toxicity to T. pyriformis, with a log(IGC50-1) of 0.557[2].
Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
Glutathione oxidized- 13C4, 15N2 is the 13C and 15N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .
Cladribine- 13C5, 15N2 (2-Chloro-2′-deoxyadenosine- 13C5, 15N2) is 13C and 15N labeled Cladribine. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
Thymidine- 13C10, 15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5
WB, ICC/IF
Human
ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.
p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243
WB
Human
P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.
ABC30 antibody;
abcC2 antibody;
ATP binding cassette sub family C (CFTR/MRP) member 2 antibody;
ATP binding cassette subfamily C member 2 antibody;
ATP-binding cassette sub-family C member 2 antibody;
Canalicular multidrug resistance protein antibody;
Canalicular multispecific organic anion transporter 1 antibody;
CMOAT antibody;
CMOAT1 antibody;
cMRP antibody;
DJS antibody;
KIAA1010 antibody;
MRP 2 antibody;
MRP2_HUMAN antibody;
Multidrug resistance associated protein 2 antibody;
Multidrug resistance-associated protein 2 antibody;
WB, ICC/IF, FC
Human
MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.
Synaptosomal-associated protein 25; SNAP-25; super protein; sup; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP
WB, ICC/IF, IP
Human, Mouse, Rat
SNAP25 Antibody (YA1412) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1412), targeting SNAP25, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). SNAP25 Antibody (YA1412) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG3-phosphonic acid diethyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
2’-Deoxy-N2,N2-diethyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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