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Results for "

PAD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (4) Antibiotic (2) Apoptosis (6) Biochemical Assay Reagents (6) Endogenous Metabolite (1) Fluorescent Dye (1) HDAC (3) Isotope-Labeled Compounds (1) MicroRNA (3) p97 (1) Phosphodiesterase (PDE) (3) Protein Arginine Deiminase (34)
By Research Areas:	Cancer (26) Cardiovascular Disease (7) Infection (2) Inflammation/Immunology (21) Neurological Disease (1)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Emulsifiers (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-155052A

PAD4-IN-2 TFA	Protein Arginine Deiminase	Cancer
PAD4-IN-2 (compound 5i) TFA is a *PAD4* inhibitor (IC₅₀=1.94 μM). PAD4-IN-2 TFA inhibits tumor growth in mice by specifically inhibiting the *PAD4-H3cit-NETs* pathway in neutrophils .

HY-135304

PAD-IN-2	Protein Arginine Deiminase	Inflammation/Immunology Cancer
PAD-IN-2 is a potent *pad4* inhibitor (IC₅₀: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis .

HY-136557A

AFM32a hydrochloride 1 Publications Verification PAD2-IN-1 hydrochloride	Protein Arginine Deiminase	Inflammation/Immunology Cancer
AFM32a (PAD2-IN-1) hydrochloride, a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a hydrochloride shows superior selectivity for *PAD2* over PAD4 (95-fold) and PAD3 (79-fold) .

HY-139088

PAD3-IN-1	Others	Neurological Disease
PAD3-IN-1 (compound 14b) is an inhibitor of protein arginine deiminase (PAD) and is more than 10-fold more selective for PAD3 than PAD 1, 2, and 4. And PAD3 is a PAD isoform associated with neurodegenerative responses to spinal cord injury, and PAD3-IN-1 could be used to study PAD-related neurological diseases .

HY-155052

PAD4-IN-2	Protein Arginine Deiminase	Cancer
PAD4-IN-2 (compound 5i) is a *PAD4* inhibitor (IC₅₀=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inhibiting the *PAD4-H3cit-NETs* pathway in neutrophils .

HY-162494

PAD4-IN-4	Protein Arginine Deiminase	Cancer
PAD4-IN-4 (compound 28) is a potent *PAD4* inhibitor (IC₅₀=0.79±0.09 μM). PAD4-IN-4 improves the tumor immune microenvironment by reshaping neutrophil phenotype, upregulating the proportions of dendritic cells and M1 macrophages, and reducing the amount of myeloid-derived suppressor cells. PAD4-IN-4 can be used for Triple-negative breast cancer research .

HY-157157

PAD4-IN-3	Protein Arginine Deiminase	Cancer
PAD4-IN-3 (compound 4B) is a *PAD4* inhibitor with antitumor activity in vitro and in vivo. PAD4-IN-3 was covalently linked to RGD sequence peptide-modified chitosan (K-CRGDV), resulting in an enhanced oxidative stress-responsive nanoagent. K-CRGDV-PAD4-IN-3 can actively target tumors, inhibit PAD4 activity, block the formation of neutrophil extracellular traps (NETs), and improve the tumor immune microenvironment in response to the tumor microenvironment .

HY-136557

AFM32a PAD2-IN-1	Protein Arginine Deiminase	Inflammation/Immunology Cancer
AFM32a (PAD2-IN-1), a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a shows superior selectivity for *PAD2* over PAD4 (95-fold) and PAD3 (79-fold) .

HY-137124

BB-F-Yne	Protein Arginine Deiminase	Cancer
BB-F-Yne is a protein arginine deiminase (PAD) inhibitor with K_i values of PAD1-4.are 2050, 1700, 1100, 3100 M ^-1min ^-1 respectively. BB-F-Yne can be used as a click probe to label PAD .

HY-137125

BB-Cl-Yne	Protein Arginine Deiminase	Cancer
BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with K_i values of PAD1-4.are 6400, 3600, 10800, 4900 M ^-1min ^-1 respectively. BB-Cl-Yne can be used as a click probe to label PAD .

HY-121705

Propionyl-L-carnitine	Endogenous Metabolite	Inflammation/Immunology
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

HY-124586A

(rac)-Streptonigrin (rac)-Bruneomycin	Protein Arginine Deiminase Antibiotic	Infection Cancer
(rac)-Streptonigrin ((rac)-Bruneomycin) is the racemic form of Streptonigrin. Streptonigrin (HY-124586) is a natural product produced by the actinobacterium Streptomyces flocculus, exhibiting antitumor and antibacterial activities. Streptonigrin can act as a *pan-PAD* inhibitor, with IC₅₀ values of 48.3 μM, 26.1 μM, 0.43 μM, and 2.5 μM for *PAD1, PAD2, PAD3, and PAD4*, respectively .

HY-124586

Streptonigrin 1 Publications Verification Bruneomycin	Protein Arginine Deiminase Antibiotic	Infection Cancer
Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a *pan-PAD* inhibitor with IC₅₀s of 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for *PAD1, PAD2, PAD3, and PAD4*, respectively .

HY-W297348

(Rac)-Cl-amidine	Others	Others
(Rac)-Cl-amidine is an orally active peptidyl arginine deimidase (PAD) inhibitor with the property of inhibiting PAD activity. (Rac)-Cl-amidine exhibits enhanced efficacy in cells and can be used to study PAD function. (Rac)-Cl-amidine can effectively regulate gene transcription, cell differentiation and innate immune response .

HY-125099

AFM-30a	Protein Arginine Deiminase	Inflammation/Immunology Cancer
AFM-30a is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a binds to PAD2 with an EC₅₀ value of 9.5 μM. AFM-30a also inhibits H3 citrullination with an EC₅₀ value of 0.4 μM. AFM-30a can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis .

HY-125099A

AFM-30a hydrochloride	Protein Arginine Deiminase	Inflammation/Immunology Cancer
AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC₅₀ value of 9.5 μM. AFM-30a hydrochloride also inhibits H3 citrullination with an EC₅₀ value of 0.4 μM. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis .

HY-111347

BB-Cl-Amidine	Protein Arginine Deiminase	Inflammation/Immunology
BB-Cl-Amidine is a peptidylarginine deminase *(PAD)* inhibitor.

HY-100574A

Cl-amidine hydrochloride 10+ Cited Publications	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-100574

Cl-amidine	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine induces apoptosis in cancer cells. Cl-amidine induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-143678

Citrulline-specific probe-biotin	Biochemical Assay Reagents	Others
Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-111347A

BB-Cl-Amidine hydrochloride 5 Publications Verification	Protein Arginine Deiminase	Inflammation/Immunology
BB-Cl-Amidine hydrochloride is a peptidylarginine deminase *(PAD)* inhibitor .

HY-100574B

Cl-amidine TFA	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-D1377

Citrulline-specific probe-rhodamine hydrate	Fluorescent Dye	Others
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

HY-117777

GSK121	Protein Arginine Deiminase	Cardiovascular Disease Inflammation/Immunology Cancer
GSK-121 Trifluoroacetates a selective *PAD4* inhibitor .

HY-100514

GSK484 hydrochloride Maximum Cited Publications 22 Publications Verification	Protein Arginine Deiminase	Cardiovascular Disease Inflammation/Immunology Cancer
GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC₅₀s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed.

HY-120343

GSK106	Protein Arginine Deiminase	Cardiovascular Disease Inflammation/Immunology Cancer
GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199 .

HY-146896S

16:0-18:1 PA-d31 sodium	Isotope-Labeled Compounds	Others
16:0-18:1 PA-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PA (sodium).

HY-100574C

D-Cl-amidine	Protein Arginine Deiminase Apoptosis	Inflammation/Immunology Cancer
D-Cl-amidine is a potent and highly selective *PAD1* inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .

HY-100574D

D-Cl-amidine hydrochloride	Protein Arginine Deiminase Apoptosis	Cancer
D-Cl-amidine hydrochloride is a potent and highly selective *PAD1* inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .

HY-103058

GSK199	Protein Arginine Deiminase	Cardiovascular Disease Inflammation/Immunology Cancer
GSK199 is an orally active, reversible, and selective *PAD4* inhibitor with an IC₅₀ of 200 nM in the absence of calcium. GSK199 can be used for the research of rheumatoid arthritis .

HY-126560

F-Amidine	Protein Arginine Deiminase	Inflammation/Immunology
F-Amidine is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .

HY-126560A

F-Amidine TFA	Protein Arginine Deiminase	Inflammation/Immunology
F-Amidine TFA is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine TFA can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .

HY-122365R

Inositol nicotinate (Standard)	Others	Cardiovascular Disease
Inositol nicotinate (Standard) is the analytical standard of Inositol nicotinate. This product is intended for research and analytical applications. Inositol nicotinate, with vasodilatory effect, is used in the study of Peripheral arterial disease (PAD) .

HY-137655

BMS-P5	Protein Arginine Deiminase	Cancer
BMS-P5 is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model .

HY-161718

MRS8028	Adenosine Receptor	Inflammation/Immunology
MRS8028 is an agonist for A3 adenosine receptor (A3AR), which binds hA3AR with K_i of 2.44 nM. MRS8028 is potential for ameliorating ischemia and inflammatory diseases .

HY-B1505

Acefylline 1 Publications Verification Theophyllineacetic acid; Theophylline-7-acetic acid	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)	Cardiovascular Disease
Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

HY-137655A

BMS-P5 free base	Protein Arginine Deiminase	Cancer
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 free base blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model .

HY-B1505A

Acefylline piperazine	Adenosine Receptor HDAC Protein Arginine Deiminase Phosphodiesterase (PDE)	Cardiovascular Disease
Acefylline piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .

HY-115676

GSK199 analog hydrochloride	Protein Arginine Deiminase	Inflammation/Immunology
GSK199 analog hydrochloride belongs to a class of compounds that inhibit PAD4 (guanidinoarginine deiminase 4). GSK199 analog hydrochloride has potential uses in diseases including rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosus, and psoriasis .

HY-B1505R

Acefylline (Standard)	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)	Others
Acefylline (Standard) is the analytical standard of Acefylline. This product is intended for research and analytical applications. Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

HY-150307

KP-302	Protein Arginine Deiminase	Inflammation/Immunology
KP-302 (compound 23) is a selective inhibitor of protein arginine deaminase PAD2 with a Ki of 60 μM. KP-302 also reversed physical disability in the EAE mouse model of multiple sclerosis (MS) and eliminated T cell infiltration in the brain. KP-302 has the potential to be a disease-modifying agent for MS .

HY-Y0850U6

PVA (Mw 205000) Polyvinyl alcohol (Mw 205000); Poly(Ethenol) (Mw 205000)	Biochemical Assay Reagents	Others
PVA (Polyvinyl alcohol) (Mw 205000) is a polyvinyl alcohol with a molecular weight of 205000, which is used as a biological excipient. PVA (Mw 205000) has excellent optical properties, high dielectric strength and excellent charge storage, and can be used as an embedded pad and substrate for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-153450

JBI-589	Protein Arginine Deiminase	Cancer
JBI-589 is a non-covalent *PAD4* isoform-selective inhibitor with oral bioavailability. JBI-589 reduces CXCR2 expression and blocks neutrophil chemotaxis. JBI-589 reduces primary tumor and metastases, and enhances the anti-tumor effect of checkpoint inhibitors. JBI-589 can be used in cancer research .

HY-Y0850A2

Polyvinyl alcohol, MW 40000 (Excipient) PVA, MW 40000 (Excipient)	Biochemical Assay Reagents	Others
Polyvinyl alcohol, MW 40000 (Excipient) (PVA, MW 40000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 40000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-Y0850A6

Polyvinyl alcohol, MW 164000 (Excipient) PVA, MW 164000 (Excipient)	Biochemical Assay Reagents	Others
Polyvinyl alcohol, MW 164000 (Excipient) (PVA, MW 164000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 164000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-Y0850A7

Polyvinyl alcohol, MW 94000 (Excipient) PVA, MW 94000 (Excipient)	Biochemical Assay Reagents	Others
Polyvinyl alcohol, MW 94000 (Excipient) (PVA, MW 94000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 94000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-110078

Eeyarestatin I 3 Publications Verification	p97 Apoptosis	Cancer
Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects .

HY-Y0850A2R

Polyvinyl alcohol, MW 40000 (Excipient) (Standard)	Biochemical Assay Reagents	Others
Polyvinyl alcohol, MW 40000 (Excipient) (Standard) is the analytical standard of Polyvinyl alcohol, MW 40000 (Excipient). This product is intended for research and analytical applications. Polyvinyl alcohol, MW 40000 (Excipient) (PVA, MW 40000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 40000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

Cat. No.	Product Name	Type

HY-D1377

Citrulline-specific probe-rhodamine hydrate

Fluorescent Dyes/Probes

Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .

Cat. No.	Product Name	Type

HY-Y0850U6

PVA (Mw 205000) Polyvinyl alcohol (Mw 205000); Poly(Ethenol) (Mw 205000)	Drug Delivery
PVA (Polyvinyl alcohol) (Mw 205000) is a polyvinyl alcohol with a molecular weight of 205000, which is used as a biological excipient. PVA (Mw 205000) has excellent optical properties, high dielectric strength and excellent charge storage, and can be used as an embedded pad and substrate for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

Cat. No.	Product Name	Target	Research Area

HY-121705

Propionyl-L-carnitine	Endogenous Metabolite	Inflammation/Immunology
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121705

Propionyl-L-carnitine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .

HY-124586

Streptonigrin 1 Publications Verification Bruneomycin	Structural Classification Classification of Application Fields Source classification Pyridine Alkaloids Infection Quinones Alkaloids Monophenols Microorganisms Phenols Benzene Quinones Disease Research Fields Cancer	Protein Arginine Deiminase Antibiotic
Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a *pan-PAD* inhibitor with IC₅₀s of 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for *PAD1, PAD2, PAD3, and PAD4*, respectively .

HY-B1505

Acefylline 1 Publications Verification Theophyllineacetic acid; Theophylline-7-acetic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)
Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

HY-B1505R

Acefylline (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	HDAC Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)
Acefylline (Standard) is the analytical standard of Acefylline. This product is intended for research and analytical applications. Acefylline, a xanthine derivative, is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .

Species:	Human (6) Mouse (3)
Tag:	His (7) GST (2)
Source:	HEK293 (3) Sf9 insect cells (3) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P78767

	PADI2 Protein, Mouse (HEK293, His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Mouse	HEK293
	Padi2 Protein functions as an enzyme that catalyzes the deimination process, specifically targeting arginine residues within proteins. PADI2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PADI2 Protein, Mouse (HEK293, His) is 673 a.a., with molecular weight of 66-88 kDa.

HY-P78767A

	PADI2 Protein, Mouse (HEK293, N-His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Mouse	HEK293
	Padi2 Protein functions as an enzyme that catalyzes the deimination process, specifically targeting arginine residues within proteins. PADI2 Protein, Mouse (HEK293, N-His) is the recombinant mouse-derived PADI2, expressed by HEK293 , with N-10*His labeled tag. ,

HY-P70990

	PADI4 Protein, Human (His) Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5	Human	E. coli
	PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses. PADI4 Protein, Human (His) is the recombinant human-derived PADI4 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P790098

	PSMD14 Protein, Mouse (His) MAD1; Psmd14; PAD1	Mouse	E. coli
	PSMD14 Protein, Mouse (His) is the recombinant mouse-derived PSMD14, expressed by E. coli , with C-6*His labeled tag. ,

HY-P701030

	PADI4 Protein, Human (Biotinylated, His) Protein-arginine deiminase type-4; HL-60 PAD; HL60 PAD; HL-60; PAD; PAD4; PADI5; PDI5	Human	E. coli
	The PADI4 protein catalyzes the citrullination of arginine residues in proteins such as histones, contributing to the histone code and stem cell regulation. PADI4 Protein, Human (Biotinylated, His) is the recombinant human-derived PADI4 protein, expressed by E. coli , with N-His labeled tag.

HY-P703022

	PAD1 Protein, Human (Active, sf9, GST) PAD1; PDI1	Human	Sf9 insect cells
	PAD1 Protein, Human (Active, sf9, GST) is the recombinant human-derived PAD1, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P78738

	PADI2 Protein, Human (HEK293, His) PADI2; PAD-H19; KIAA0994; PAD2; PDI2	Human	HEK293
	The PADI2 protein serves as a catalyst for the deimination process, specifically targeting arginine residues within proteins and facilitating their conversion. PADI2 Protein, Human (HEK293, His) is the recombinant human-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PADI2 Protein, Human (HEK293, His) is 665 a.a., with molecular weight of 66-85 kDa.

HY-P703052

	PAD6 Protein, Human (sf9, GST) PADI6	Human	Sf9 insect cells
	PAD6 Protein, Human (sf9, GST) is the recombinant human-derived PAD6, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P77121

	PADI4 Protein, Human (sf9, His) Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; PADI5; PDI5	Human	Sf9 insect cells
	PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses. PADI4 Protein, Human (sf9, His) is the recombinant human-derived PADI4 protein, expressed by Sf9 insect cells , with N-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-146896S

16:0-18:1 PA-d31 sodium
16:0-18:1 PA-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PA (sodium).

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HY-P82505

	PSMD14 Antibody (YA2250) 26S proteasome non-ATPase regulatory subunit 14; PAD1; POH1; Psmd14; RPN11	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	PSMD14 Antibody (YA2250) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2250), targeting PSMD14, with a predicted molecular weight of 35 kDa (observed band size: 35 kDa). PSMD14 Antibody (YA2250) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-137124

BB-F-Yne		Alkynes
BB-F-Yne is a protein arginine deiminase (PAD) inhibitor with K_i values of PAD1-4.are 2050, 1700, 1100, 3100 M ^-1min ^-1 respectively. BB-F-Yne can be used as a click probe to label PAD .

HY-137125

BB-Cl-Yne		Alkynes
BB-Cl-Yne is a protein arginine deiminase (PAD) inhibitor with K_i values of PAD1-4.are 6400, 3600, 10800, 4900 M ^-1min ^-1 respectively. BB-Cl-Yne can be used as a click probe to label PAD .

Cat. No.	Product Name		Classification

HY-Y0850A2

Polyvinyl alcohol, MW 40000 (Excipient) PVA, MW 40000 (Excipient)		Emulsifiers
Polyvinyl alcohol, MW 40000 (Excipient) (PVA, MW 40000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 40000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-Y0850A6

Polyvinyl alcohol, MW 164000 (Excipient) PVA, MW 164000 (Excipient)		Emulsifiers
Polyvinyl alcohol, MW 164000 (Excipient) (PVA, MW 164000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 164000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

HY-Y0850A7

Polyvinyl alcohol, MW 94000 (Excipient) PVA, MW 94000 (Excipient)		Emulsifiers
Polyvinyl alcohol, MW 94000 (Excipient) (PVA, MW 94000 (Excipient)) is a polyvinyl alcohol (PVA) with a molecular weight of 94000, which is used as a bioexcipient. Polyvinyl alcohol has good optical properties, high dielectric strength and excellent charge storage capacity. Polyvinyl alcohol can be used as an embedding pad and matrix for metal/inorganic nanofillers for sensing, optoelectronic devices and many other applications .

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