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SC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) ADC Antibody (1) ADC Cytotoxin (2) ADC Linker (2) Akt (2) Aldose Reductase (1) Aminopeptidase (2) Androgen Receptor (7) Angiotensin Receptor (1) Antibiotic (7) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (16) Arenavirus (2) Autophagy (5) Bacterial (11) Biochemical Assay Reagents (6) Calcium Channel (2) Caspase (1) Complement System (1) COX (24) Dengue virus (1) Dihydroorotate Dehydrogenase (2) Drug Metabolite (2) Drug-Linker Conjugates for ADC (3) EBV (1) EGFR (1) Elastase (1) Endogenous Metabolite (12) Endonuclease (1) Epigenetic Reader Domain (1) ERK (1) Factor Xa (2) FLT3 (1) Fluorescent Dye (1) Fungal (3) FXR (2) HDAC (4) HIV (1) HPPD (2) IKK (1) Influenza Virus (1) Interleukin Related (5) Isotope-Labeled Compounds (14) JAK (1) Leukotriene Receptor (2) Liposome (2) MDM-2/p53 (2) Microtubule/Tubulin (1) Mineralocorticoid Receptor (11) MMP (1) Na+/K+ ATPase (1) NF-κB (1) Opioid Receptor (2) p38 MAPK (1) Parasite (2) Phosphatase (1) Phosphodiesterase (PDE) (2) Pim (1) PKC (2) Polo-like Kinase (PLK) (1) Potassium Channel (3) PPAR (1) Prostaglandin Receptor (7) PROTAC Linkers (4) Renin (1) Ribosomal S6 Kinase (RSK) (1) SARS-CoV (1) Small Interfering RNA (siRNA) (3) Sodium Channel (3) STAT (2) TGF-β Receptor (1) TRP Channel (1) VEGFR (1) Virus Protease (1) α-synuclein (1)
By Research Areas:	Cancer (65) Cardiovascular Disease (21) Endocrinology (7) Infection (24) Inflammation/Immunology (40) Metabolic Disease (10) Neurological Disease (18)
Click Chemistry:	DBCO (1) Alkynes (1)
Oligonucleotides:	Pre-designed siRNA Sets (2) Cationic Lipids (2) Polymers (6) Sweetening Agents (1) siRNAs (4)

171

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136657

SC-43 4 Publications Verification	Phosphatase STAT Apoptosis	Cancer
SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects .

HY-W013164

SC-58125	COX	Inflammation/Immunology Cancer
SC-58125 is a potent and selective inhibitor of cyclooxygenase 2 (COX-2), with an IC₅₀ of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo. SC-58125 also can inhibit edema at the inflammatory site and has analgesic effect .

HY-102065

SC-19220	Prostaglandin Receptor	Others
SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis .

HY-108562

SC-51322	Prostaglandin Receptor	Neurological Disease
SC-51322 is a potent and selective antagonist of prostaglandin E2 (PGE₂) receptor (EP ₁), with a pA₂ of 8.1. SC-51322 has the pain-relieving effect .

HY-100931

SC-10	PKC	Cancer
SC-10 is a direct activator of PKC .

HY-123354

SC 44914	Bacterial	Infection
SC 44914 is a quinoxaline compound with antibacterial effects. SC-44914 has activity against Campylobacter jejuni, C. coli, and Clostridium difficile .

HY-117896

SC-50605	Leukotriene Receptor	Inflammation/Immunology
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases. .

HY-112739

SC-41930	Leukotriene Receptor	Inflammation/Immunology
SC-41930 is a orally active eukotriene-B4 receptor antagonist. SC-41930 alleviates inflammation in guinea pig acetic acid-induced colonic inflammation model .

HY-118795

SC-22716	Aminopeptidase	Inflammation/Immunology
SC-22716 is a potent, competitive, reversible inhibitor of human LTA₄ hydrolase, with an IC₅₀ of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis .

HY-123156

SC-23110	Bacterial	Infection
SC-23110 is a potent anti-acne agent. SC-23110 inhibits the growth of P. acnes, one of the organisms associated with acne, and most frequently mentioned as the organism involved in the pathogenesis of inflammatory pustules/lesions .

HY-129982

SC-435	Apical Sodium-Dependent Bile Acid Transporter	Metabolic Disease
SC-435 is an orally effective apical sodium codependent bile acid transporter (ASBT) inhibitor. SC-435 effectively removes neurotoxic bile acids and ammonia from the blood by inhibiting intestinal ASBT, thereby alleviating liver and brain damage caused by liver failure. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations .

HY-W010983

SC-236 1 Publications Verification	COX PPAR Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
SC-236 is an orally active COX-2 specific inhibitor (IC₅₀ = 10 nM) and a PPARγ agonist. SC-236 suppresses activator protein-1 (AP-1) through c-Jun NH2-terminal kinase. SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model .

HY-19500

SC-75416	Others	Others
SC-75416 is a selective cyclooxygenase-2 inhibitor. Its pharmacokinetic/pharmacodynamic (PK/PD) model was used for development and clinical trial simulation to design a study protocol to verify its analgesic effect in a post-oral surgery pain model. The simulation results showed that 360 mg of SC-75416 may provide better pain relief than 400 mg of ibuprofen. The actual clinical trial results confirmed this hypothesis, and 360 mg of SC-75416 was indeed superior to 400 mg of ibuprofen in pain relief. The PK/PD model of SC-75416 showed good predictive performance and successfully predicted its clinical effect. These research results show that SC-75416, as a new selective COX-2 inhibitor, has potential clinical application value in the management of post-oral surgery pain.

HY-122134

SC-58272	Fungal	Infection
SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC₅₀ of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme .

HY-120776

SC-51316	Angiotensin Receptor	Cardiovascular Disease
SC-51316 is an oral active angiotensin II receptor antagonist with the IC₅₀ values of 3.6 and 5.1 nM in rat adrenal cortical and rat uterine membrane, respectively. SC-51316 shows antihypertensive activity in vivo and in vitro .

HY-P99506

Tamrintamab SC-003 mAb; SC-Mab003; SC34.28ss1	ADC Antibody	Cancer
Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 (DPEP3 or MBD3). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research .

HY-59105

SC-560 2 Publications Verification	COX	Cancer
SC-560 is a potent and selective COX-1 inhibitor with an IC₅₀ of 9 nM.

HY-120586

SC-46944	Renin	Cardiovascular Disease
SC-46944 is an orally active renin inhibitor and can be used for study of hypertension .

HY-105052

SC 34301 Enisoprost	Prostaglandin Receptor	Endocrinology
SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice .

HY-123747

SC-53116	5-HT Receptor	Neurological Disease
SC-53116 is a selective 5-HT4 receptor agonist with EC₅₀ at 23 nM .

HY-123747A

SC-53116 hydrochloride	5-HT Receptor	Neurological Disease
SC-53116 hydrochloride is a selective 5-HT4 receptor agonist with EC₅₀ at 23 nM .

HY-122288

SC 28538	Bacterial	Infection
SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms .

HY-112333

SC-68376	p38 MAPK	Inflammation/Immunology
SC-68376 is a potent, reversible, ATP-competitive, and selective inhibitor of p38 MAP kinase inhibitor .

HY-161409

SC912	Androgen Receptor Apoptosis	Cancer
SC912 is an AR-V7 inhibitor (IC₅₀ = 0.36 μM). SC912 possesses safety, potency and selectivity. SC912 binds directly to AR-FL and AR-V7 proteins, inhibites nuclear localization and chromatin binding capabilities. SC912 exerts anticancer activity through inhibition of proliferation, induction of cell cycle arrest and apoptosis .

HY-10496

SC75741 10+ Cited Publications	NF-κB Influenza Virus	Infection Cancer
SC75741 is a broad and efficient NF-κB inhibitor with an IC₅₀ of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .

HY-164373

SC428	Androgen Receptor Apoptosis	Cancer
SC428 is an androgen receptor (AR) inhibitor that targets the N-terminal domain. SC428 potently decrease the transactivation of (AR)-V7, (AR)v567es, as well as full-length ( AR ) (AR-FL) and its LBD mutants, substantially. SC428 inhibits androgen-stimulated (AR)-FL nuclear translocation, chromatin binding, and (AR) -regulated gene transcription. SC428 inhibits the proliferation of tumor cells in vitro. SC428 inhibits tumor cell growth by inducing apoptosis in mice transplanted with 22RV1 .

HY-123229

Ropizine SC 13504	Others	Neurological Disease
Ropizine (SC 13504) is a benzhydryl piperazine with anticonvulsant properties .

HY-148194

SC239	Drug-Linker Conjugates for ADC	Cancer
SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC . SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-108563

SC 51089	Prostaglandin Receptor	Neurological Disease
SC 51089 is a selective antagonist of prostaglandin E₂ EP1 receptor, with K_is of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 exhibits neuroprotective activity .

HY-15614

SC144 5+ Cited Publications	Interleukin Related Apoptosis	Cancer
SC144 is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 shows potent inhibition of gp130 ligand-triggered signaling. SC144 induces apoptosis in human ovarian cancer cells .

HY-15614A

SC144 hydrochloride 5+ Cited Publications	Interleukin Related Apoptosis	Cancer
SC144 hydrochloride is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 hydrochloride shows potent inhibition of gp130 ligand-triggered signaling. SC144 hydrochloride induces apoptosis in human ovarian cancer cells .

HY-124858

SC99	STAT JAK Apoptosis	Cardiovascular Disease Cancer
SC99 is an orally active, selective STAT3 inhibitor targeting JAK2-STAT3 pathway. SC99 docks into the ATP-binding pocket of JAK2. SC99 inhibits phosphorylation of JAK2 and STAT3 with no effects on the other kinases associated with STAT3 signaling. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities .

HY-125494

Droxinavir hydrochloride SC-55389A	HIV	Infection
Droxinavir (SC-55389A) hydrochloride is an antiviral compound that functions as an HIV protease inhibitor.

HY-400056

SC209 intermediate-2	ADC Cytotoxin	Cancer
SC209 intermediate-2 (Compound A9) is an intermediate of the ADC cytotoxin SC209 (HY-144880). SC209 intermediate-2 is an ADC Linker .

HY-18749

SC79 Maximum Cited Publications 187 Publications Verification	Akt	Neurological Disease Inflammation/Immunology Cancer
SC79, a unique specific and BBB permeable Akt activator, activates Akt in the cytosol and inhibits Akt membrane translocation. SC79 specifically binds to the PH domain of Akt .

HY-144880

SC209	ADC Cytotoxin EGFR Drug Metabolite	Cancer
SC209, an ADC cytotoxin extracted from patent WO2021247798, is used in synthesis of anti-EGFR antibody-drug conjugate ADC. SC209 is the payload of STRO-002 .

HY-121598

Actisomide SC-36602	Apoptosis	Cardiovascular Disease
Actisomide (SC-36602) is an antiarrhythmic agent. Absorption of actisomide in rats and its in vitro uptake in CaCo-2 cells are pH-dependent .

HY-107410

SC-26196 2 Publications Verification	Others	Inflammation/Immunology
SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC₅₀=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties .

HY-U00129

SC57666	COX	Inflammation/Immunology
SC57666 is a selective COX2 inhibitor with an IC₅₀ of 26 nM.

HY-U00239

SC58451	COX	Inflammation/Immunology
SC58451 is a potent and selective Cox-2 inhibitor.

HY-125337

SC4453	Na+/K+ ATPase	Cardiovascular Disease
SC4453 is a digoxin analogue in which the lactone ring at C17β is replaced by a pyrazine ring. SC4453 is slightly inferior to digoxin in inhibiting (Na+ + K+)-ATPase, but shows similar sensitivity to potassium ions. The differences in the sensitivity of SC4453 to heart and brain tissue from different species are mainly due to differences in its dissociation rate from the receptor. These observations confirm the high sensitivity of the human heart to cardiac glycosides.

HY-100934

SC-9 NCM 119	PKC	Endocrinology Cancer
SC-9 is a PKC activator in the presence of Ca ²⁺ .

HY-14908A

Vidofludimus hemicalcium 4SC-101 hemicalcium; SC12267 hemicalcium	Dihydroorotate Dehydrogenase Interleukin Related FXR	Infection Inflammation/Immunology
Vidofludimus (4sc-101; SC12267) hemicalcium is an orally active inhibitor for dihydroorotate dehydrogenase (DHODH) and also is a novel modulator for farnesoid X receptor (FXR). Vidofludimus hemicalcium, as an immunomodulatory agent, can be used for the research of autoimmune disorders such as inflammatory bowel disease (IBD). Vidofludimus hemicalcium also can be used for the research of fatty liver by targeting FXR .

HY-108563A

SC 51089 free base 1 Publications Verification	Prostaglandin Receptor	Neurological Disease
SC 51089 free base is a selective antagonist of prostaglandin E₂ EP1 receptor, with K_is of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 free base exhibits neuroprotective activity .

HY-47968

SC209 intermediate-1	ADC Linker	Cancer
SC209 intermediate-1 (Compound A7a) is an ADC linker. SC209 intermediate-1 can be used for synthesis of ADCs .

HY-120113

SC-2001	Others	Others
SC-2001 is a compound structurally related to obatoclax that has better antitumor effects than obatoclax in liver cancer cell lines, downregulating Mcl-1 protein levels, inhibiting STAT3 phosphorylation, inducing apoptosis, and enhancing SHP1 expression and activity.

HY-U00232

Bidisomide SC40230	Others	Cardiovascular Disease
Bidisomide (SC40230) is a class I antiarrhythmic agent.

HY-103226

SC-57461A 1 Publications Verification	Aminopeptidase	Inflammation/Immunology
SC-57461A is a potent, orally active, nonpeptide, and selective inhibitor of Leukotriene A4 (LTA4) hydrolase with IC₅₀s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .

HY-126681

SC-VC-PAB-MMAE 2 Publications Verification	Drug-Linker Conjugates for ADC	Cancer
SC-VC-PAB-MMAE is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB .

HY-139678

SC13	Opioid Receptor	Others
SC13 is a novel mitragynine analog with low-efficacy Mu opioid receptor agonism that displays antinociception with attenuated adverse effects.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15762

Valdecoxib 3 Publications Verification SC 65872	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	COX Endogenous Metabolite
Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC₅₀s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain.

HY-B1341

Norethynodrel Enidrel; SC 4642; NSC 15432	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
Norethynodrel (Enidre) is a 19-nortestosterone derivative to be used as a progestagen. Norethynodrel can be used for researching inhibition of ovulation . Norethynodrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1438

Canrenone 1 Publications Verification Aldadiene; SC9376	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Mineralocorticoid Receptor Endogenous Metabolite
Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

HY-B1438R

Canrenone (Standard) 1 Publications Verification Aldadiene(Standard); SC9376 (Standard)	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids	Mineralocorticoid Receptor Endogenous Metabolite
Canrenone (Standard) is the analytical standard of Canrenone. This product is intended for research and analytical applications. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

HY-Y0079

D-Phenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014 .

HY-N9319

Fulvotomentoside A Decaisoside E	Triterpenes Classification of Application Fields Terpenoids Lardizabalaceae Source classification Other Diseases Plants Decaisnea insignis (Griffith) J. D. Hooker et Thomson Disease Research Fields	Others
Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .

HY-W004297

1-Nonadecanol	Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO₂) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata .

HY-125337

SC4453	Triterpenes Structural Classification Animals Terpenoids Source classification	Na+/K+ ATPase
SC4453 is a digoxin analogue in which the lactone ring at C17β is replaced by a pyrazine ring. SC4453 is slightly inferior to digoxin in inhibiting (Na+ + K+)-ATPase, but shows similar sensitivity to potassium ions. The differences in the sensitivity of SC4453 to heart and brain tissue from different species are mainly due to differences in its dissociation rate from the receptor. These observations confirm the high sensitivity of the human heart to cardiac glycosides.

HY-N12871

Floramanoside D	Malvaceae Structural Classification Flavonoids Flavones Source classification Abelmoschus manihot (Linn.) Medicus Plants	Aldose Reductase
Floramanoside D is a flavonol glycoside. Floramanoside D inhibits aldose reductase (IC₅₀ is 2.2 μM), scavenges the 2,2-diphenyl-1-picrylhydrazyl (DPPH) (SC₅₀ is 12.5 μM) .

HY-Y0079R

D-Phenylalanine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
D-Phenylalanine (Standard) is the analytical standard of D-Phenylalanine. This product is intended for research and analytical applications. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014 .

HY-N12164

Linearmycin B	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Fungal
Linearmycin B is an antibacterial and antifungal agent. Linearmycin B shows activity against Bacillus subtilis (Bs), Staphylococcus aureus (Sa). Candida albicans (Ca), and Saccharomyces cerevisiae (Sc), with MIC values of 0.097, 1.5, 0.0008, and 0.0002 μg/mL, respectively .

HY-W004297R

1-Nonadecanol (Standard)	Structural Classification Natural Products other families Source classification Plants	Others
1-Nonadecanol (Standard) is the analytical standard of 1-Nonadecanol. This product is intended for research and analytical applications. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata .

Cat. No.	Product Name	Chemical Structure

HY-B0561S1

Spironolactone-d3
Spironolactone-d₃ is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].

HY-B0561S

Spironolactone-d7
Spironolactone-d₇ is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].

HY-14398S1

Celecoxib-d3
Celecoxib-d₃ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM[1][2].

HY-14398S

Celecoxib-d7
Celecoxib-d₇ is the deuterium labeled Celecoxib. Celecoxib,a selective non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC50 of 40 nM[1][2].

HY-B0361S

Aspartame-d3
Aspartame-d₃ is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%)[1][2].

HY-B0561S2

Spironolactone-d3-1
Spironolactone-d₃-1 is deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].

HY-17474S

Parecoxib-d3

Parecoxib-d3 is the deuterium labeled Parecoxib. Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.

HY-17474AS

Parecoxib-d5 sodium

Parecoxib-d5 (sodium) is the deuterium labeled Parecoxib sodium. Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo[1][2].

HY-17509S

Deracoxib-d3
Deracoxib-d₃ is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

HY-15762S

Valdecoxib-d3
Valdecoxib-d₃ is the deuterium labeled Valdecoxib. Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain[1][2].

HY-B0318AS

Metronidazole-d4 hydrochloride
Metronidazole-d₄ (hydrochloride) is the deuterium labeled Metronidazole hydrochloride[1].

HY-B1438S

Canrenone-d6
Canrenone-d₆ is the deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

HY-B1438S1

Canrenone-d4
Canrenone-d₄ is deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

HY-Y0079S

D-Phenylalanine-d5
D-Phenylalanine-d₅ is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].

HY-Y0079S1

D-Phenylalanine-d8
D-Phenylalanine-d₈ is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].

HY-B0361S1

Aspartame-d5
Aspartame-d₅ is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%)[1][2].

HY-B0455S

Lomefloxacin-d5 hydrochloride
Lomefloxacin-d₅ (hydrochloride) is the deuterium labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc.[1][2].

HY-118827S

Vedaprofen-d3
Vedaprofen-d₃ is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition [1]. Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM[2].

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