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TGFB1 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Tgfb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tgfb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Tgfb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tgfb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
TGFB1I1 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFB1I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator [1].
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, significantly decreases the level of fibronectin in High-Glucose and TGF-b1 induced HK-2 cells with 27.66 % inhibition rate at 10 μM [1].
3-OH-Kynurenamine dihydroiodide is the dihydroiodide form of 3-OH-Kynurenamine (HY-156908). 3-OH-Kynurenamine dihydroiodide is an activator for aryl hydrocarbon receptor (AhR), and thus regulates the immune response. 3-OH-Kynurenamine dihydroiodide upregulates the expressions of Ido1 and Tgfb1, ameliorates the skin inflammation in psoriasis mouse model and kidney damage in nephrotoxic lupus mouse model [1].
QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 μM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research [1].
Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator [1].
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid (compound 3), a triterpenoid, significantly decreases the level of fibronectin in High-Glucose and TGF-b1 induced HK-2 cells with 27.66 % inhibition rate at 10 μM [1].
TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. TGF beta 1/TGFB1 LAP Protein, Human (HEK293) is the recombinant human-derived TGF beta 1/TGFB1 LAP protein, expressed by HEK293 , with tag free. and C33S mutation.
TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF-β-1) chain, which maintains TGF-β-1 latency in the extracellular matrix. TGFB1 binds non-covalently to TGF-β-1 and interacts with “environmental molecules” (LTBP1, LRRC32/GARP, LRRC33/NRROS) to regulate TGF-β-1 activation. TGF beta 1/TGFB1 Protein, Canine (HEK293, His) is the recombinant canine-derived TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of TGF beta 1/TGFB1 Protein, Canine (HEK293, His) is 361 a.a..
Latent TGF beta 1 (latent TGFB1) is the inactive form of TGF-B1. Latent TGF beta 1 associates with the extracellular matrix (ECM) via LTBP. LTBPs are components of the ECM, so that the proteolytic cleavage of LTBP can lead to the release of latent TGF-beta 1 from the matrix. Besides, the proteolytic cleavage and liberation of active TGFB1 is performed by BMP-1, by a variety of matrix metalloproteinases (MMPs). Latent TGF beta 1/TGFB1 Protein, Rat (HEK293, His) is the recombinant rat-derived Latent TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Latent TGF beta 1/TGFB1 Protein, Rat (HEK293, His) is 361 a.a., with molecular weight of ~55 & 38 & 16 kDa, respectively.
TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. TGF beta 1/TGFB1 LAP Protein, Human (HEK293, His) is the recombinant human-derived TGF beta 1/TGFB1 Latency-associated peptide protein, expressed by HEK293 , with C-10*His labeled tag and C33S mutation.
TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, N-Avi) is a recombinant protein (A279-S390) produced by HEK293 cells with Avi tag.
TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. Latent TGF beta 1/TGFB1 Protein, Human (HEK293, His) is the recombinant human-derived Latent TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-His labeled tag.
TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human is a recombinant protein (A279-S390) produced by CHO cells.
Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. Latent TGF beta 1/TGFB1 Protein, Cynomolgus (C33S, HEK293, His) is a recombinant protein (L30-S390, C33S) produced by HEK293 cells with His tag.
TGF beta 1 is a secreted ligand of the TGF-beta superfamily that binds to receptors and activates SMAD transcription factors. Preproprotein is proteolytically processed to produce latency-associated peptide (LAP) and mature peptide. TGF beta 1/TGFB1 LAP Protein, Human (HEK293, N-His) is the recombinant human-derived TGF beta 1/TGFB1 Latency-associated peptide protein, expressed by HEK293 , with N-6*His labeled tag and C33S mutation.
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Rat (HEK293, hFc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 103 amino acids (M21-E123).
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Canine (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag.
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 101 amino acids (M1-E123).
TGF beta-1/TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF-beta-1) chain, which maintains TGF-beta-1 latency in the extracellular matrix. It interacts with "environmental molecules" (LTBP1, LRRC32/GARP, LRRC33/NRROS) and plays a crucial regulatory role in the activation of TGF-β-1. TGF beta 1/TGFB1 Protein, Oncorhynchus mykiss (P. pastoris, His) is the recombinant TGF beta 1/TGFB1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of TGF beta 1/TGFB1 Protein, Oncorhynchus mykiss (P. pastoris, His) is 112 a.a., with molecular weight of 15 kDa.
TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF-β-1) chain, which maintains TGF-β-1 latency in the extracellular matrix. Through non-covalent binding, TGFB1 critically regulates TGF-β-1 activation by interacting with “environmental molecules” (LTBP1, LRRC32/GARP, LRRC33/NRROS) that collectively control TGF-β-1 activation. TGF beta 1/TGFB1 Protein, Xenopus laevis (P. pastoris, His) is the recombinant Xenopus laevis-derived TGF beta 1/TGFB1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of TGF beta 1/TGFB1 Protein, Xenopus laevis (P. pastoris, His) is 112 a.a., with molecular weight of 14.6 kDa.
Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Mouse (HEK293, His-hFc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag . It consists of 123 amino acids (M1-E123).
Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. Latent TGF beta 1/TGFB1 Protein, Human (C33S, HEK293, His) is a recombinant Biotinylated protein (L30-S390) produced by HEK293 cells with His tag.
Transforming growth factor beta-1 (TGF-beta-1) proprotein, comprising Latency-associated peptide (LAP) and active TGF-beta-1 chains, forms a homodimer with disulfide linkages. Upon activation, proteolytic processing releases mature TGF-beta-1, enabling its regulatory functions in cell growth, differentiation, and immune responses. The dimeric structure emphasizes LAP and TGF-beta-1's intricate interplay in orchestrating multifaceted activities within biological systems. TGF beta 1/TGFB1 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived TGF beta 1/TGFB1 protein, expressed by HEK293 , with N-His labeled tag and C33S mutation. The total length of TGF beta 1/TGFB1 Protein, Rhesus Macaque (HEK293, His) is 361 a.a., with molecular weight of 40-50/14-15 kDa.
Latent TGF beta 1 (latent TGFB1) is the inactive form of TGF-B1. Latent TGF beta 1 associates with the extracellular matrix (ECM) via LTBP. LTBPs are components of the ECM, so that the proteolytic cleavage of LTBP can lead to the release of latent TGF-beta 1 from the matrix. Besides, the proteolytic cleavage and liberation of active TGFB1 is performed by BMP-1, by a variety of matrix metalloproteinases (MMPs). Latent TGF beta 1/TGFB1 Protein, Rat (HEK293, C-His) is the recombinant rat-derived Latent TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Latent TGF beta 1/TGFB1 Protein, Rat (HEK293, C-His) is 361 a.a., with molecular weight of ~55 & 40 & 16 kDa, respectively.
TGF beta 1/TGFB1 Protein, Mouse/Rat (HEK293), is a recombinant cytokine produced in HEK293 cells, is implicated as a key regulator of the development and cyclic remodelling characteristic of reproductive tissues.
TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. GMP TGF beta 1/TGFB1 Protein, Human (HEK293) is a GMP-grade recombinant protein (A279-S390) produced by CHO cells.
TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human (HEK293) is a recombinant protein (A279-S390) produced by HEK293 cells.
Transforming growth factor beta-1 proprotein is the precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains. TGF beta 1/TGFB1 Protein, Mouse (HEK293, His) is a recombinant protein (L30-S390) produced by HEK293 cells with His tag.
TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. Mature TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, Avi) is the recombinant human-derived Mature TGF beta 1/TGFB1 protein, expressed by HEK293 , with C-Avi labeled tag. The total length of Mature TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, Avi) is 112 a.a., with molecular weight of 15-18 kDa.
The latency-associated peptide (LAP) of the transforming growth factor β-1 (TGF-β-1) proprotein is an important precursor that forms a complex with TGF-β-1. LAP maintains the latent state of TGF-β-1 during storage in the extracellular matrix, ensuring controlled activation. Interactions with “environmental molecules” such as LTBP1, LRRC32/GARP, and LRRC33/NRROS intricately regulate TGF-β-1 activation. LRRC33/NRROS influences the activation of macrophages and microglia, while LRRC32/GARP controls the activation of activated regulatory T cells. Interactions with integrins induce conformational changes in LAP, releasing active TGF-β-1. LAP orchestrates controlled TGF-β-1 activation in different physiological contexts. Recombinant human TGF beta 1/TGFB1 LAP (biotinylated, expressed in HEK293 cells, Avi-tagged) is a biotinylated, Avi-tagged LAP protein expressed in HEK293 cells.
Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. Latent TGF beta 1/TGFB1 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant Biotinylated protein (L30-S390, C33S) produced by HEK293 cells with His-Avi tag.
TGF beta 1/TGFB1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. TGF beta 1 is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, apoptosis, and can regulate the expression and activation of other growth factors, including interferon gamma and tumor necrosis factor alpha. Animal-Free TGF beta 1/TGFB1 Protein, Human (His) is the recombinant human-derived animal-FreeTGF beta 1/TGFB1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TGF beta 1/TGFB1 Protein, Human (His) is 112 a.a., with molecular weight of ~13.7 kDa.
TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Mouse (HEK293) is a recombinant protein (A279-S390) produced by HEK293 cells.
In its proprotein form, the TGF beta-1/TGFB1 protein serves as a precursor to latency-associated peptide (LAP) and active transforming growth factor beta-1 (TGF-beta-1) chains.Critical to maintaining the latent state of TGF-β-1 within the extracellular matrix, preprotein interacts with “environmental molecules” such as LTBP1, LRRC32/GARP, and LRRC33/NRROS to regulate TGF-β-1 activation.Animal-Free TGF beta 1/TGFB1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeTGF beta 1/TGFB1 protein, expressed by E.coli , with C-His labeled tag.
TGFB1 proprotein is the precursor of latency-associated peptide (LAP) and active transforming growth factor Beta-1 (TGF-β-1) chain, which maintains TGF-β-1 latency in the extracellular matrix. TGFB1 binds non-covalently to TGF-β-1 and regulates its activation through interactions with “environmental molecules” (LTBP1, LRRC32/GARP, LRRC33/NRROS). Animal-Free TGF beta 1/TGFB1 Protein, Pig (His) is the recombinant pig-derived animal-FreeTGF beta 1/TGFB1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free TGF beta 1/TGFB1 Protein, Pig (His) is 112 a.a., with molecular weight of ~13.7 kDa.
TSC22D1 Protein, a positive modulator of cell death during mammary gland involution in response to TGFB3, forms a heterodimer with TSC22D4/THG1. Its interactions with histone H1-2 and GNL3 underscore TSC22D1's versatile role in molecular processes, emphasizing its potential significance in various cellular contexts. TSC22/TSC22D1 Protein, Human (His) is the recombinant human-derived TSC22/TSC22D1 protein, expressed by E. coli , with N-His labeled tag. The total length of TSC22/TSC22D1 Protein, Human (His) is 144 a.a., with molecular weight of ~20 kDa.
TSC22D1 protein, possessing RNA polymerase II binding activity, regulates apoptotic and cell proliferation processes. It is found in the cytoplasm and nucleus and expressed in multiple structures like the alimentary system and central nervous system. With ubiquitous expression observed, TSC22D1 likely regulates diverse cellular processes across tissues. TSC22/TSC22D1 Protein, Mouse (His) is the recombinant mouse-derived TSC22/TSC22D1 protein, expressed by E. coli , with N-His labeled tag.
GARP/latent TGF-b1 complexes are potent inducers of Th17 differentiation in the presence of exogenous IL-6 and inducers of Treg in the presence of IL-2. GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His) is a biotinylated recombinant protein (GARP (I18-N628)&TGF-b1 (L30-S390)) produced by HEK293 cells with His tag.
LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 72-80 kDa.
LRRC32, a key regulator of TGF-beta activation, maintains TGFB1, TGFB2, and TGFB3 in a latent state during extracellular storage by binding to Latency-associated peptide (LAP). Competing with LTBP1 for LAP binding, LRRC32 effectively modulates integrin-dependent TGF-beta activation. Its significance spans the regulation of TGF-beta-1 (TGFB1) on activated Tregs' surface and the control of TGF-beta-3 (TGFB3) during palate development, emphasizing LRRC32's intricate role in fine-tuning TGF-beta signaling. Interactions with TGFB1, TGFB2, TGFB3, and LAPTM4B contribute to its regulatory functions. GARP&Latent TGF beta Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF beta Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. GARP&Latent TGF beta Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of (73-78) kDa (GARP) & 13 kDa & (42-45) kDa (Latent TGF beta 1), respectively.
GARP/latent TGF-b1 complexes are potent inducers of Th17 differentiation in the presence of exogenous IL-6 and inducers of Treg in the presence of IL-2. GARP&Latent TGF beta Complex Protein, Mouse (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant protein (GARP (I18-N628)&TGF-b1 (L30-S390)) produced by HEK293 cells with His-Avi tag.
LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP (Mutated) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP (Mutated) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 75-80 kDa.
LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP (Y137H) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP (Y137H) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 71-75 kDa.
LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP (S138G) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP, expressed by HEK293 , with C-His, C-Avi labeled tag. GARP (S138G) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 75-80 kDa.
LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP). LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP (G139N) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP (G139N) &Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 75-80 kDa.
LRRC32, a key regulator of TGF-beta activation, maintains TGFB1, TGFB2, and TGFB3 in a latent state during extracellular storage by binding to Latency-associated peptide (LAP). Competing with LTBP1 for LAP binding, LRRC32 effectively modulates integrin-dependent TGF-beta activation. Its significance spans the regulation of TGF-beta-1 (TGFB1) on activated Tregs' surface and the control of TGF-beta-3 (TGFB3) during palate development, emphasizing LRRC32's intricate role in fine-tuning TGF-beta signaling. Interactions with TGFB1, TGFB2, TGFB3, and LAPTM4B contribute to its regulatory functions. GARP&Latent TGF Beta-1 Complex Protein, Human (HEK293, His, Strep) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta-1 Complex protein, expressed by HEK293, with N-6*His, C-3*Strep labeled tag. GARP&Latent TGF Beta-1 Complex Protein, Human (HEK293, His, Strep), has molecular weight of 10-14 & 35-50 & 85-95 kDa, respectively.
TGFBR1/ALK-5 proteins cooperate with TGFBR2 to form dedicated receptors for TGFB1, TGFB2, and TGFB3, transmitting signals and coordinating different physiological and pathological processes. It induces cell cycle arrest, modulates mesenchymal cell dynamics, contributes to wound healing, and affects immunosuppression and carcinogenesis. TGFBR1/ALK-5 Protein, Human (HEK293, mFc-Avi) is the recombinant human-derived TGFBR1/ALK-5 protein, expressed by HEK293 , with C-Avi, C-mFc labeled tag. The total length of TGFBR1/ALK-5 Protein, Human (HEK293, mFc-Avi) is 92 a.a., with molecular weight of 50-60 kDa.
GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.
GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.
TGFB1 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Tgfb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tgfb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Tgfb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tgfb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
TGFB1I1 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFB1I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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