Search Result
Results for "
Xanthone
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0126
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- HY-N0126R
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Bacterial
Influenza Virus
Fungal
Apoptosis
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Infection
Inflammation/Immunology
Cancer
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Xanthone (Standard) is the analytical standard of Xanthone. This product is intended for research and analytical applications. Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities .
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- HY-N2795
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Xanthone I
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Parasite
Bacterial
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Infection
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9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
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- HY-N3347
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Maclurin
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Others
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Others
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Macurin is a xanthone that can be isolated from Garcinia lancilimba .
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- HY-N10985
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- HY-N2964
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Others
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Others
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BR-xanthone A is a xanthone that can be extracted from the dried husk of mangosteen.
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- HY-N0986
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Others
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Cancer
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1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone is a nature product that could be isolated from the stem barks of Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone has antiproliferative active. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone can be used in research of cancer .
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- HY-N8557
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Others
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Others
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1,5-Dihydroxyxanthone (Compound 5) is a xanthone that can be isolated from the root of Garcinia cowa .
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- HY-N1651
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Others
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Others
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2,3',4,6-Tetrahydroxybenzophenone, a kind of benzophenone, is the immediate precursor of xanthones in higher plants .
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- HY-N12801
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Others
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Others
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3-Hydroxy-1,2-dimethoxyxanthone is a xanthone derivative and can be isolated from Polygala nitida .
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- HY-W031510
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Others
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Cancer
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3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research .
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- HY-N8345
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Others
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Others
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Isocudraniaxanthone B (compound 10) is a kind of xanthone. Isocudraniaxanthone B can be isolated from Calophyllum caledonicum. Isocudraniaxanthone B has antimalarial activity with an IC50 value of 3.2 μg/mL .
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- HY-N15136
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Apoptosis
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Cancer
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Isomorellinol is a xanthone with an anticancer potency. Isomorellinol induces apoptosis in cholangiocarcinoma cells. Isomorellinol increases the Bax/Bcl-2 protein expression ratio and decreases survivin protein expression in cholangiocarcinoma cells .
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- HY-N8338
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Parasite
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Infection
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Pancixanthone A is a xanthone that can be isolated from Garcinia vieillardii. Pancixanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 1.6 μg/mL .
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- HY-N8455
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AssiguXanthone A
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Parasite
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Infection
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Isocudraniaxanthone A is a xanthone that can be isolated from Garcinia vieillardii. Isocudraniaxanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 2.3 μg/mL .
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- HY-N8424
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Others
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Cancer
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1,5,6-Trihydroxy-3-methoxyxanthone is a xanthone that can be found in Hypericum perforatum L.. 1,5,6-Trihydroxy-3-methoxyxanthone shows antioxidant activity and cytotoxicity .
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- HY-N2050
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Desmethylbellidifolin
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Others
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Neurological Disease
Inflammation/Immunology
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1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .
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- HY-N0723
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Others
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Metabolic Disease
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Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
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- HY-N3883
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Autophagy
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Neurological Disease
Cancer
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Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities .
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- HY-123901
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Apoptosis
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Cancer
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Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas .
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- HY-N9113
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Others
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Cardiovascular Disease
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1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
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- HY-N0723R
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Others
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Metabolic Disease
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Neomangiferin (Standard) is the analytical standard of Neomangiferin. This product is intended for research and analytical applications. Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
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- HY-N0983
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Bacterial
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Inflammation/Immunology
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1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum) .
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- HY-N10677
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Others
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Cancer
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S-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. S-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 4.49 and 3.61 μM for K562/R and K562/S, respectively. S-30-Hydroxygambogic acid can be used for the research of cancer .
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- HY-N10678
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Others
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Cancer
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R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
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- HY-N10836
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Others
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Others
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Montixanthone is a xanthone that can be found in Cudrania fruticosa .
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- HY-N2171
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Others
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Others
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Sibiricaxanthone B is a xanthone isolated from Polygala tenuifolia .
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- HY-N8727
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Others
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Cancer
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Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research .
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- HY-N9045
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Others
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Others
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7-Prenyljacareubin is a natural xanthone found in Garcinia gardneriana .
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- HY-N4304
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Others
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Cancer
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Gambogellic acid is an xanthone isolated from the processed gamboge, with antitumor activity .
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- HY-N3465
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Others
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Others
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Isonormangostin is a Xanthones product that can be isolated from the fruits of Garcinia mangostana .
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- HY-N7499
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Others
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Others
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Sibiricaxanthone A, a xanthone C-glycoside, is isolated from the roots of Polygala sibirica .
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- HY-N6247
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Others
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Others
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Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca .
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- HY-N8897
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Others
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Others
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Ugaxanthone is a Xanthones product that can be isolated from the herbs of Symphonia globulifera L. .
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- HY-N3189
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Others
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Others
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Nigrolineaxanthone V is a Xanthones product that can be isolated from the fruits of Garcinia mangostana L. .
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- HY-N3784
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Others
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Others
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Drimiopsin C is a Xanthones product that can be isolated from the herbs of Scilla scilloides .
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- HY-N3647
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Others
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Others
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Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata .
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- HY-N9041
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Others
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Others
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Pyranojacareubin is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .
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- HY-N8895
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Others
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Others
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Onjixanthone II is a Xanthones product that can be isolated from the roots of Polygala tenuifolia. .
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- HY-N9152
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Others
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Others
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Parvifolixanthone B is a Xanthones product that can be isolated from the twigs of Garcinia parvifolia. .
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- HY-N2873
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Others
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Others
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Angustin B is a Xanthones product that can be isolated from the aerial parts of Swertia angustifolia. .
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- HY-N4293
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Others
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Others
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1,2,3,7-Tetramethoxyxanthone is a xanthone isolated from Polygala tenuifolia .
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- HY-N9138
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Others
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Others
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Tovopyrifolin C is a Xanthones product that can be isolated from the stem barks of Calophyllum venulosum. .
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- HY-N12794
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Others
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Others
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1,2,3-Trimethoxyxanthone is a xanthone and can be isolated from Psorospermum adamauense .
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- HY-N8252
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Antibiotic
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Infection
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Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .
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- HY-N9001
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Others
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Others
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Cadensin D is a Xanthones product that can be isolated from the stems and leaves of Hypericum japonicum. .
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- HY-N3295
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Others
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Inflammation/Immunology
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Mesuaxanthone A is a xanthone with anti-inflammatory activities. Mesuaxanthone A shows typical CNS depressant effects .
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- HY-168063
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Bacterial
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Infection
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Antibiofilm agent-11 (compound C12) is a xanthone derivative with anti-biofilm activity .
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- HY-N1197
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1,4,5-TrihydroxyXanthone
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Others
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Others
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Subelliptenone G is a simple oxygenated xanthone that can be isolated from the root bark of Garcinia subelliptica .
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- HY-N9370
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Fungal
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Infection
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Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect .
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- HY-N1297
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NSC380470
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Others
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Others
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Sesartemin (NSC380470) is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .
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- HY-115480
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Others
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Others
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1,3,5-Trihydroxyxanthone is a Xanthones product that can be isolated from the herbs of Calophyllum inophyllum L. .
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- HY-N8891
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Others
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Others
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1,2,5-Trihydroxyxanthone is a Xanthones product that can be isolated from the barks of Garcinia tetralata. .
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- HY-N9219
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Others
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Others
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2,5-Dihydroxyxanthone is a Xanthones product that can be isolated from the stem barks of Garcinia tetrandra .
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- HY-N12786
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Others
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Others
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1,3-Dihydroxy-2-methoxyxanthone is a xanthone and can be isolated from Polygala caudata .
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- HY-N9269
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Others
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Others
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1,7-Dihydroxy-2,3-dimethoxyxanthone is a xanthone that can be found in Polygala cyparissias .
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- HY-N6248
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Bacterial
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Infection
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Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
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- HY-N6803
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Others
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Neurological Disease
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Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent .
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- HY-124365
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Others
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Infection
Cancer
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Rhamnetin tetraacetate (compound 4) is a xanthone compound with antiplatelet activity. Rhamnetin tetraacetate inhibited platelet aggregation induced by arachidonic acid .
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- HY-N8665
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Others
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Others
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1,7-Dihydroxy-4-methoxyxanthone is a Xanthones product that can be isolated from the woods of Cratoxylum maingayi. .
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- HY-N8702
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Others
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Others
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2,5-Dihydroxy-1-methoxyxanthone is a Xanthones product that can be isolated from the twigs of Mammea siamensis. .
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- HY-N8732
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Others
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Others
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1,7-Dimethoxy-2,3-methylenedioxyxanthone is a Xanthones product that can be isolated from the roots of Polygala tenuifolia .
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- HY-N1843
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Bacterial
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Infection
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3-Isomangostin hydrate (Compound 17) is an xanthone that can be isolated from Cratoxylum formosum ssp. pruniflorum and exhibits antibacterial activity .
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- HY-N10157
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Others
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Others
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1,3,7-Trihydroxy-2-methoxyxanthone is a Xanthones product that can be isolated from the roots of Polygala fallax. .
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- HY-N1868
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Others
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Others
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3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
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- HY-N8863
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Others
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Others
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6-Hydroxy-1,2,3,7-tetramethoxyxanthone is a Xanthones product that can be isolated from the roots of Polygala sibirica L. .
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- HY-N2192
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- HY-N1623
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- HY-N3324
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(+)-Mangostanol
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Phosphodiesterase (PDE)
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Others
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Mangostanol ((+)-Mangostanol) is a polyoxygenated xanthone mangostanol, which can be isolated from the shell of Garcinia mangostana, and has inhibitory effect on cAMP phosphodiesterase (PDE) .
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- HY-N2872
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Others
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Others
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Angustin A (1,8-Dihydroxy-4,6,7-trimethoxyxanthone) is a xanthones that can be isolated from the aerial parts of Swertia angustifolia .
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- HY-N9341
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Autophagy
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Cancer
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Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy .
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- HY-N1000
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Others
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Others
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1,7-Dihydroxy-3-methoxy-2-prenylxanthone is a Xanthones product that can be isolated from the fruits of Garcinia mangostana .
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- HY-N8857
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Reactive Oxygen Species
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Others
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Parvifolixanthone A is a xanthone compound that can be isolated from Garcinia parvifolia. Parvifolixanthone A exhibits antioxidant activity with IC50 of submicromolar level (0.18–0.38 μM) .
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- HY-N2702
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Others
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Others
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6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
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- HY-N2768
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Others
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Others
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8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
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- HY-N9156
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Others
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Others
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Methyl 1,6-dihydroxy-3-methylxanthone-8-carboxylate is a Xanthones product that can be isolated from the roots of Polygala tenuifolia Willd .
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- HY-N9261
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Others
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Others
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3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa. .
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- HY-N6038
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Autophagy
Fungal
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Cancer
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Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells .
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- HY-N14911
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Antibiotic
Bacterial
Fungal
DNA/RNA Synthesis
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Infection
Cancer
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Actinoplanone A is a polycyclic xanthone antibiotic. Actinoplanone A has strong antimicrobial activities against bacteria and the rice blast fungus. Actinoplanone A is cytotoxic to various tumor cells and has an inhibitory effect on DNA synthesis .
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- HY-114716
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Bacterial
Reactive Oxygen Species
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Cancer
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Jacareubin is a xanthone compound that can be isolated from Calophyllum brasiliense. Jacareubin has antibacterial, antioxidant, gastroprotective properties, and also has certain cancer cell toxicity, which can be used in cancer research .
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- HY-N12785
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Others
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Cardiovascular Disease
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Methoxy-2,3-methylenedioxyxanthone (Compound 5) is a xanthone that can be isolated from the roots of Polygala caudata. Methoxy-2,3-methylenedioxyxanthone has antioxidant and vasodilatory effects .
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- HY-162252
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Sirtuin
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Others
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SIRT2-IN-12 (Compound 3) is a SIRT2 inhibitor with a IC50 value of 50 μM .
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- HY-149373
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Angiotensin-converting Enzyme (ACE)
SARS-CoV
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Infection
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Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19 .
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- HY-N2000
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HIV
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Infection
Inflammation/Immunology
Cancer
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Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .
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- HY-N2192R
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Cholinesterase (ChE)
HBV
Bacterial
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Infection
Inflammation/Immunology
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Swertianolin (Standard) is the analytical standard of Swertianolin. This product is intended for research and analytical applications. Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity .
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- HY-N3928
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Others
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Neurological Disease
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Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .
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- HY-N8362
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Lipase
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Metabolic Disease
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1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity .
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- HY-N6038R
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Autophagy
Fungal
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Cancer
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Gartanin (Standard) is the analytical standard of Gartanin. This product is intended for research and analytical applications. Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells .
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- HY-N2707
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Reactive Oxygen Species
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Neurological Disease
Cancer
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6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS) .
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- HY-N0328
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α-Mangostin
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Reactive Oxygen Species
Apoptosis
Bacterial
Fungal
Virus Protease
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Cancer
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alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
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- HY-W013557
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3-Hydroxy-xanthen-9-one
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Integrin
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Inflammation/Immunology
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3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs). 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression .
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- HY-N6009
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Parasite
NF-κB
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Infection
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8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE) . 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum . 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM .
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- HY-W665338
-
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Apoptosis
|
Cancer
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3,6-Dimethoxy-9H-xanthen-9-one is a Xanthone (HY-N0126) derivative. 3,6-Dimethoxy-9H-xanthen-9-one can be used to synthesize compounds with apoptosis-inducing activity in cancer cells .
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- HY-N11457
-
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Others
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Others
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Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch .
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- HY-N0328R
-
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α-Mangostin (Standard)
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Fungal
Reactive Oxygen Species
Bacterial
Apoptosis
Virus Protease
|
Cancer
|
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alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
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- HY-N0985
-
|
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Others
|
Cancer
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1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone is a xanthone that can be isolated from Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone shows moderate cytotoxicities against MDA-MB-435S and A549 cell lines with IC50s of 1.3 and 3.86 渭g/ml, respectively .
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- HY-N6953
-
|
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STAT
Keap1-Nrf2
Reactive Oxygen Species
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Neurological Disease
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Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners .
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- HY-126640
-
|
|
Parasite
|
Infection
Cancer
|
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Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
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- HY-N0941
-
|
β-Mangostin
|
Bacterial
Parasite
Apoptosis
|
Infection
Cancer
|
|
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
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- HY-N14035
-
|
|
ATP Citrate Lyase
|
Cardiovascular Disease
Metabolic Disease
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Garcinia cambogia extract contains several active compounds, including hydroxycitric acid (HCA) (an ECC inhibitor), xanthones, benzophenones, hydroxycitric acid (an ATP-citrate lyase inhibitor). Garcinia cambogia extract lowers the body weight gain, visceral fat accumulation, blood and hepatic lipid concentrations, and plasma insulin and leptin levels in a high-fat diet (HFD)-induced obesity mouse model. Garcinia cambogia extract is promising for research of fatty liver, dyslipidemia, hyperinsulinemia and hyperleptinemia rendered by HFD .
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- HY-N12166
-
|
|
Src
|
Cardiovascular Disease
|
|
2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56 lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease .
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- HY-N6953R
-
|
|
STAT
Keap1-Nrf2
Reactive Oxygen Species
|
Neurological Disease
|
|
Garcinone D (Standard) is the analytical standard of Garcinone D. This product is intended for research and analytical applications. Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration-and time-dependent manners .
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- HY-N6954
-
|
|
ATM/ATR
STAT
CDK
Hedgehog
|
Inflammation/Immunology
Cancer
|
|
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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- HY-N0941R
-
|
|
Bacterial
Parasite
Apoptosis
|
Infection
Cancer
|
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beta-Mangostin (Standard) is the analytical standard of beta-Mangostin. This product is intended for research and analytical applications. beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
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- HY-N6954R
-
|
|
ATM/ATR
STAT
CDK
Hedgehog
|
Cancer
|
|
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N9219
-
-
- HY-N12786
-
-
- HY-N9269
-
-
- HY-N6248
-
-
- HY-N6803
-
-
- HY-N8665
-
-
- HY-N8702
-
-
- HY-N8732
-
-
- HY-N1843
-
-
- HY-N10157
-
-
- HY-N1868
-
-
- HY-N8863
-
-
- HY-N2192
-
-
- HY-N1623
-
-
- HY-N3324
-
-
- HY-N2872
-
-
- HY-N9341
-
-
- HY-N1000
-
-
- HY-N8857
-
-
- HY-N2702
-
-
- HY-N2768
-
-
- HY-N9156
-
-
- HY-N9261
-
-
- HY-N6038
-
-
- HY-N14911
-
-
- HY-114716
-
-
- HY-N12785
-
-
- HY-149373
-
-
- HY-N2000
-
-
- HY-N2192R
-
-
- HY-N3928
-
-
- HY-N8362
-
-
- HY-N6038R
-
-
- HY-N2707
-
-
- HY-N0328
-
-
- HY-N6009
-
-
- HY-N11457
-
-
- HY-N0328R
-
-
- HY-N0985
-
-
- HY-N6953
-
-
- HY-126640
-
|
|
Quinones
Structural Classification
Microorganisms
Anthraquinones
Source classification
|
Parasite
|
|
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
|
-
- HY-N0941
-
-
- HY-N14035
-
|
|
Structural Classification
Natural Products
Guttiferae
Source classification
Garcinia cambogia Desr.
Plants
|
ATP Citrate Lyase
|
|
Garcinia cambogia extract contains several active compounds, including hydroxycitric acid (HCA) (an ECC inhibitor), xanthones, benzophenones, hydroxycitric acid (an ATP-citrate lyase inhibitor). Garcinia cambogia extract lowers the body weight gain, visceral fat accumulation, blood and hepatic lipid concentrations, and plasma insulin and leptin levels in a high-fat diet (HFD)-induced obesity mouse model. Garcinia cambogia extract is promising for research of fatty liver, dyslipidemia, hyperinsulinemia and hyperleptinemia rendered by HFD .
|
-
- HY-N12166
-
|
|
Cardiovascular Disease
Structural Classification
Flavonoids
Microorganisms
Classification of Application Fields
Marine natural products
Source classification
Other Flavonoids
Marine microorganism
Disease Research Fields
|
Src
|
|
2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56 lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease .
|
-
- HY-N6953R
-
-
- HY-N6954
-
-
- HY-N0941R
-
|
|
Structural Classification
Xanthones
Guttiferae
Source classification
Phenols
Polyphenols
Garcinia mangostana Linn.
Plants
|
Bacterial
Parasite
Apoptosis
|
|
beta-Mangostin (Standard) is the analytical standard of beta-Mangostin. This product is intended for research and analytical applications. beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
|
-
- HY-N6954R
-
|
|
Structural Classification
other families
Xanthones
Garcinia oblongifolia Champ. ex Benth.
Guttiferae
Source classification
Phenols
Polyphenols
Plants
|
ATM/ATR
STAT
CDK
Hedgehog
|
|
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
|
-
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