Search Result
Results for "
Xanthones
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N0126R
-
|
|
Monoamine Oxidase
Calcium Channel
|
Cardiovascular Disease
Neurological Disease
|
|
Xanthone (Standard) is the analytical standard of Xanthone (HY-N0126). This product is intended for research and analytical applications. Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM. Xanthon inhibits Norepinephrine (HY-13715) and high-K +-induced vasoconstriction with IC50 values of 60.26 μM and 82.9 μM, respectively. Xanthon increases intracellular cyclic adenosine 3′,5′-monophosphate (cAMP) content and blocks of Ca 2+ channels. Xanthone is the scaffold of several pharmacologically active compounds .
|
-
-
- HY-N3347
-
|
Maclurin
|
Others
|
Others
|
|
Macurin is a xanthone that can be isolated from Garcinia lancilimba .
|
-
-
- HY-W031510
-
|
|
Others
|
Cancer
|
|
3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research .
|
-
-
- HY-N8557
-
|
|
Others
|
Others
|
|
1,5-Dihydroxyxanthone (Compound 5) is a xanthone that can be isolated from the root of Garcinia cowa .
|
-
-
- HY-N1651
-
|
|
Others
|
Others
|
|
2,3',4,6-Tetrahydroxybenzophenone, a kind of benzophenone, is the immediate precursor of xanthones in higher plants .
|
-
-
- HY-N12801
-
|
|
Others
|
Others
|
|
3-Hydroxy-1,2-dimethoxyxanthone is a xanthone derivative and can be isolated from Polygala nitida .
|
-
-
- HY-N8345
-
|
|
Others
|
Others
|
|
Isocudraniaxanthone B (compound 10) is a kind of xanthone. Isocudraniaxanthone B can be isolated from Calophyllum caledonicum. Isocudraniaxanthone B has antimalarial activity with an IC50 value of 3.2 μg/mL .
|
-
-
- HY-N15136
-
|
|
Apoptosis
|
Cancer
|
|
Isomorellinol is a xanthone with an anticancer potency. Isomorellinol induces apoptosis in cholangiocarcinoma cells. Isomorellinol increases the Bax/Bcl-2 protein expression ratio and decreases survivin protein expression in cholangiocarcinoma cells .
|
-
-
- HY-N8455
-
|
Assiguxanthone A
|
Parasite
|
Infection
|
|
Isocudraniaxanthone A is a xanthone that can be isolated from Garcinia vieillardii. Isocudraniaxanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 2.3 μg/mL .
|
-
-
- HY-N8338
-
|
|
Parasite
|
Infection
|
|
Pancixanthone A is a xanthone that can be isolated from Garcinia vieillardii. Pancixanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 1.6 μg/mL .
|
-
-
- HY-N8424
-
|
|
Others
|
Cancer
|
|
1,5,6-Trihydroxy-3-methoxyxanthone is a xanthone that can be found in Hypericum perforatum L.. 1,5,6-Trihydroxy-3-methoxyxanthone shows antioxidant activity and cytotoxicity .
|
-
-
- HY-N2050
-
|
Desmethylbellidifolin
|
Others
|
Neurological Disease
Inflammation/Immunology
|
|
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity .
|
-
-
- HY-N0723
-
|
|
Others
|
Metabolic Disease
|
|
Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
|
-
-
- HY-N3883
-
|
|
Autophagy
|
Neurological Disease
Cancer
|
|
Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities .
|
-
-
- HY-123901
-
|
|
Apoptosis
|
Cancer
|
|
Garcinone E is a natural xanthone found in the rind of the mangosteen fruit. Garcinone E induces apoptosis and inhibits cancer cell migration. Garcinone E has anticancer effects on different human cancer cell lines, including colorectal, breast, and hepatocellular carcinomas .
|
-
-
- HY-N9113
-
|
|
Others
|
Cardiovascular Disease
|
|
1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats .
|
-
-
- HY-N0723R
-
|
|
Others
|
Metabolic Disease
|
|
Neomangiferin (Standard) is the analytical standard of Neomangiferin. This product is intended for research and analytical applications. Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats .
|
-
-
- HY-N0983
-
|
|
Bacterial
|
Inflammation/Immunology
|
|
1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum) .
|
-
-
- HY-N10677
-
|
|
Others
|
Cancer
|
|
S-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. S-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 4.49 and 3.61 μM for K562/R and K562/S, respectively. S-30-Hydroxygambogic acid can be used for the research of cancer .
|
-
-
- HY-N10678
-
|
|
Others
|
Cancer
|
|
R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer .
|
-
-
- HY-N2964
-
|
|
Others
|
Others
|
|
BR-xanthone A is a xanthone that can be extracted from the dried husk of mangosteen.
|
-
-
- HY-N10985
-
-
-
- HY-N10836
-
|
|
Others
|
Others
|
|
Montixanthone is a xanthone that can be found in Cudrania fruticosa .
|
-
-
- HY-N2171
-
|
|
Others
|
Others
|
|
Sibiricaxanthone B is a xanthone isolated from Polygala tenuifolia .
|
-
-
- HY-N8727
-
|
|
Others
|
Cancer
|
|
Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research .
|
-
-
- HY-N9045
-
|
|
Others
|
Others
|
|
7-Prenyljacareubin is a natural xanthone found in Garcinia gardneriana .
|
-
-
- HY-N4304
-
|
|
Others
|
Cancer
|
|
Gambogellic acid is an xanthone isolated from the processed gamboge, with antitumor activity .
|
-
-
- HY-N2795
-
|
Xanthone I
|
Parasite
Bacterial
|
Infection
|
|
9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM) .
|
-
-
- HY-N3465
-
|
|
Others
|
Others
|
|
Isonormangostin is a Xanthones product that can be isolated from the fruits of Garcinia mangostana .
|
-
-
- HY-N7499
-
|
|
Others
|
Others
|
|
Sibiricaxanthone A, a xanthone C-glycoside, is isolated from the roots of Polygala sibirica .
|
-
-
- HY-N6247
-
|
|
Others
|
Others
|
|
Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca .
|
-
-
- HY-N8897
-
|
|
Others
|
Others
|
|
Ugaxanthone is a Xanthones product that can be isolated from the herbs of Symphonia globulifera L. .
|
-
-
- HY-N3784
-
|
|
Others
|
Others
|
|
Drimiopsin C is a Xanthones product that can be isolated from the herbs of Scilla scilloides .
|
-
-
- HY-N3647
-
|
|
Others
|
Others
|
|
Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata .
|
-
-
- HY-N3189
-
|
|
Others
|
Others
|
|
Nigrolineaxanthone V is a Xanthones product that can be isolated from the fruits of Garcinia mangostana L. .
|
-
-
- HY-N9041
-
|
|
Others
|
Others
|
|
Pyranojacareubin is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .
|
-
-
- HY-N8895
-
|
|
Others
|
Others
|
|
Onjixanthone II is a Xanthones product that can be isolated from the roots of Polygala tenuifolia. .
|
-
-
- HY-N9152
-
|
|
Others
|
Others
|
|
Parvifolixanthone B is a Xanthones product that can be isolated from the twigs of Garcinia parvifolia. .
|
-
-
- HY-N2873
-
|
|
Others
|
Others
|
|
Angustin B is a Xanthones product that can be isolated from the aerial parts of Swertia angustifolia. .
|
-
-
- HY-N4293
-
|
|
Others
|
Others
|
|
1,2,3,7-Tetramethoxyxanthone is a xanthone isolated from Polygala tenuifolia .
|
-
-
- HY-N9138
-
|
|
Others
|
Others
|
|
Tovopyrifolin C is a Xanthones product that can be isolated from the stem barks of Calophyllum venulosum. .
|
-
-
- HY-N12794
-
|
|
Others
|
Others
|
|
1,2,3-Trimethoxyxanthone is a xanthone and can be isolated from Psorospermum adamauense .
|
-
-
- HY-N8252
-
|
|
Antibiotic
|
Infection
|
|
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .
|
-
-
- HY-N9001
-
|
|
Others
|
Others
|
|
Cadensin D is a Xanthones product that can be isolated from the stems and leaves of Hypericum japonicum. .
|
-
-
- HY-N3295
-
|
|
Others
|
Inflammation/Immunology
|
|
Mesuaxanthone A is a xanthone with anti-inflammatory activities. Mesuaxanthone A shows typical CNS depressant effects .
|
-
-
- HY-N0986
-
|
|
Others
|
Cancer
|
|
1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone is a nature product that could be isolated from the stem barks of Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone has antiproliferative active. 1,4,5,6-Tetrahydroxy-7-(3-methylbut-2-enyl)xanthone can be used in research of cancer .
|
-
-
- HY-N1197
-
|
1,4,5-Trihydroxyxanthone
|
Others
|
Others
|
|
Subelliptenone G is a simple oxygenated xanthone that can be isolated from the root bark of Garcinia subelliptica .
|
-
-
- HY-N9370
-
|
|
Fungal
|
Infection
|
|
Isobellidifolin, a xanthone, is a free radical scavenger and antioxidant compound. Isobellidifolin has potent antifungal effect .
|
-
-
- HY-168063
-
|
|
Bacterial
|
Infection
|
|
Antibiofilm agent-11 (compound C12) is a xanthone derivative with anti-biofilm activity .
|
-
-
- HY-N1297
-
|
NSC380470
|
Others
|
Others
|
|
Sesartemin (NSC380470) is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .
|
-
- HY-115480
-
|
|
Others
|
Others
|
|
1,3,5-Trihydroxyxanthone is a Xanthones product that can be isolated from the herbs of Calophyllum inophyllum L. .
|
-
- HY-N8891
-
|
|
Others
|
Others
|
|
1,2,5-Trihydroxyxanthone is a Xanthones product that can be isolated from the barks of Garcinia tetralata. .
|
-
- HY-N9219
-
|
|
Others
|
Others
|
|
2,5-Dihydroxyxanthone is a Xanthones product that can be isolated from the stem barks of Garcinia tetrandra .
|
-
- HY-N9269
-
|
|
Others
|
Others
|
|
1,7-Dihydroxy-2,3-dimethoxyxanthone is a xanthone that can be found in Polygala cyparissias .
|
-
- HY-N6248
-
|
|
Bacterial
|
Infection
|
|
Cowaxanthone B is a xanthone isolated from the fruits of Garcinia cowa. Cowaxanthone B has weak antibacterial activity .
|
-
- HY-N12786
-
|
|
Others
|
Others
|
|
1,3-Dihydroxy-2-methoxyxanthone is a xanthone and can be isolated from Polygala caudata .
|
-
- HY-N6803
-
|
|
Others
|
Neurological Disease
|
|
Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent .
|
-
- HY-124365
-
|
|
Others
|
Infection
Cancer
|
|
Rhamnetin tetraacetate (compound 4) is a xanthone compound with antiplatelet activity. Rhamnetin tetraacetate inhibited platelet aggregation induced by arachidonic acid .
|
-
- HY-N8665
-
|
|
Others
|
Others
|
|
1,7-Dihydroxy-4-methoxyxanthone is a Xanthones product that can be isolated from the woods of Cratoxylum maingayi. .
|
-
- HY-N8702
-
|
|
Others
|
Others
|
|
2,5-Dihydroxy-1-methoxyxanthone is a Xanthones product that can be isolated from the twigs of Mammea siamensis. .
|
-
- HY-N8732
-
|
|
Others
|
Others
|
|
1,7-Dimethoxy-2,3-methylenedioxyxanthone is a Xanthones product that can be isolated from the roots of Polygala tenuifolia .
|
-
- HY-N1843
-
|
|
Bacterial
|
Infection
|
|
3-Isomangostin hydrate (Compound 17) is an xanthone that can be isolated from Cratoxylum formosum ssp. pruniflorum and exhibits antibacterial activity .
|
-
- HY-N10157
-
|
|
Others
|
Others
|
|
1,3,7-Trihydroxy-2-methoxyxanthone is a Xanthones product that can be isolated from the roots of Polygala fallax. .
|
-
- HY-N1868
-
|
|
Others
|
Others
|
|
3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
|
-
- HY-N0126
-
|
|
Monoamine Oxidase
Calcium Channel
|
Cardiovascular Disease
Neurological Disease
|
|
Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM. Xanthon inhibits Norepinephrine (HY-13715) and high-K +-induced vasoconstriction with IC50 values of 60.26 μM and 82.9 μM, respectively. Xanthon increases intracellular cyclic adenosine 3′,5′-monophosphate (cAMP) content and blocks of Ca 2+ channels. Xanthone is the scaffold of several pharmacologically active compounds .
|
-
- HY-N8863
-
|
|
Others
|
Others
|
|
6-Hydroxy-1,2,3,7-tetramethoxyxanthone is a Xanthones product that can be isolated from the roots of Polygala sibirica L. .
|
-
- HY-N2192
-
-
- HY-N1623
-
-
- HY-N3324
-
|
(+)-Mangostanol
|
Phosphodiesterase (PDE)
|
Others
|
|
Mangostanol ((+)-Mangostanol) is a polyoxygenated xanthone mangostanol, which can be isolated from the shell of Garcinia mangostana, and has inhibitory effect on cAMP phosphodiesterase (PDE) .
|
-
- HY-N2872
-
|
|
Others
|
Others
|
|
Angustin A (1,8-Dihydroxy-4,6,7-trimethoxyxanthone) is a xanthones that can be isolated from the aerial parts of Swertia angustifolia .
|
-
- HY-N9341
-
|
|
Autophagy
|
Cancer
|
|
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy .
|
-
- HY-N1000
-
|
|
Others
|
Others
|
|
1,7-Dihydroxy-3-methoxy-2-prenylxanthone is a Xanthones product that can be isolated from the fruits of Garcinia mangostana .
|
-
- HY-N8857
-
|
|
Reactive Oxygen Species
|
Others
|
|
Parvifolixanthone A is a xanthone compound that can be isolated from Garcinia parvifolia. Parvifolixanthone A exhibits antioxidant activity with IC50 of submicromolar level (0.18–0.38 μM) .
|
-
- HY-N2702
-
|
|
Others
|
Others
|
|
6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
|
-
- HY-N2768
-
|
|
Others
|
Others
|
|
8-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane is a Xanthones product that can be isolated from the herbs of Garcinia cowa .
|
-
- HY-N9156
-
|
|
Others
|
Others
|
|
Methyl 1,6-dihydroxy-3-methylxanthone-8-carboxylate is a Xanthones product that can be isolated from the roots of Polygala tenuifolia Willd .
|
-
- HY-N9261
-
|
|
Others
|
Others
|
|
3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa. .
|
-
- HY-N6038
-
|
|
Autophagy
Fungal
|
Cancer
|
|
Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells .
|
-
- HY-N14911
-
|
|
Antibiotic
Bacterial
Fungal
DNA/RNA Synthesis
|
Infection
Cancer
|
|
Actinoplanone A is a polycyclic xanthone antibiotic. Actinoplanone A has strong antimicrobial activities against bacteria and the rice blast fungus. Actinoplanone A is cytotoxic to various tumor cells and has an inhibitory effect on DNA synthesis .
|
-
- HY-162252
-
|
|
Sirtuin
|
Others
|
|
SIRT2-IN-12 (Compound 3) is a SIRT2 inhibitor with a IC50 value of 50 μM .
|
-
- HY-N12785
-
|
|
Others
|
Cardiovascular Disease
|
|
Methoxy-2,3-methylenedioxyxanthone (Compound 5) is a xanthone that can be isolated from the roots of Polygala caudata. Methoxy-2,3-methylenedioxyxanthone has antioxidant and vasodilatory effects .
|
-
- HY-114716
-
|
|
Bacterial
Reactive Oxygen Species
|
Cancer
|
|
Jacareubin is a xanthone compound that can be isolated from Calophyllum brasiliense. Jacareubin has antibacterial, antioxidant, gastroprotective properties, and also has certain cancer cell toxicity, which can be used in cancer research .
|
-
- HY-149373
-
|
|
Angiotensin-converting Enzyme (ACE)
SARS-CoV
|
Infection
|
|
Garcinone B, a xanthone derivative, is a nature product that could be isolated from the pericarp of Mangosteen. Garcinone B is a potent ACE2 and Mpro inhibitor. Garcinone B can be used in research of COVID-19 .
|
-
- HY-N2000
-
|
|
HIV
|
Infection
Inflammation/Immunology
Cancer
|
|
Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities . Bellidifolin also acts as a viral protein R (Vpr) inhibitor .
|
-
- HY-N2192R
-
|
|
Cholinesterase (ChE)
HBV
Bacterial
|
Infection
Inflammation/Immunology
|
|
Swertianolin (Standard) is the analytical standard of Swertianolin. This product is intended for research and analytical applications. Swertianolin, a xanthone isolated from Gentianella Acuta, inhibits acetylcholinesterase (AChE). Swertianolin also exhibits anti-HBV and anti-bacterial activity .
|
-
- HY-N3928
-
|
|
Others
|
Neurological Disease
|
|
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .
|
-
- HY-N15370
-
|
|
Bacterial
|
Infection
|
|
Morellin is a caged-tetraprenylated xanthone compound found in the fruits of Garcinia hanburyi, exhibiting antibacterial activity with a minimum inhibitory concentration (MIC) of 200 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA), and can be utilized in anti-infective research .
|
-
- HY-N8362
-
|
|
Lipase
|
Metabolic Disease
|
|
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity .
|
-
- HY-N6038R
-
|
|
Autophagy
Fungal
|
Cancer
|
|
Gartanin (Standard) is the analytical standard of Gartanin. This product is intended for research and analytical applications. Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells .
|
-
- HY-N2707
-
|
|
Reactive Oxygen Species
|
Neurological Disease
Cancer
|
|
6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS) .
|
-
- HY-N0328
-
|
α-Mangostin
|
Reactive Oxygen Species
Apoptosis
Bacterial
Fungal
Virus Protease
|
Cancer
|
|
alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
|
-
- HY-W013557
-
|
3-Hydroxy-xanthen-9-one
|
Integrin
|
Inflammation/Immunology
|
|
3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs). 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression .
|
-
- HY-N6009
-
|
|
Parasite
NF-κB
|
Infection
|
|
8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE) . 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum . 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM .
|
-
- HY-W665338
-
|
|
Apoptosis
|
Cancer
|
|
3,6-Dimethoxy-9H-xanthen-9-one is a Xanthone (HY-N0126) derivative. 3,6-Dimethoxy-9H-xanthen-9-one can be used to synthesize compounds with apoptosis-inducing activity in cancer cells .
|
-
- HY-N11457
-
|
|
Others
|
Others
|
|
Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch .
|
-
- HY-N0328R
-
|
α-Mangostin (Standard)
|
Fungal
Reactive Oxygen Species
Bacterial
Apoptosis
Virus Protease
|
Cancer
|
|
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
|
-
- HY-N0985
-
|
|
Others
|
Cancer
|
|
1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone is a xanthone that can be isolated from Garcinia xanthochymus. 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone shows moderate cytotoxicities against MDA-MB-435S and A549 cell lines with IC50s of 1.3 and 3.86 μg/ml, respectively .
|
-
- HY-N6953
-
|
|
STAT
Keap1-Nrf2
Reactive Oxygen Species
|
Neurological Disease
|
|
Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners .
|
-
- HY-126640
-
|
|
Parasite
|
Infection
Cancer
|
|
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
|
-
- HY-N0941
-
|
β-Mangostin
|
Bacterial
Parasite
Apoptosis
|
Infection
Cancer
|
|
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
|
-
- HY-N14035
-
|
|
ATP Citrate Lyase
|
Cardiovascular Disease
Metabolic Disease
|
|
Garcinia cambogia extract contains several active compounds, including hydroxycitric acid (HCA) (an ECC inhibitor), xanthones, benzophenones, hydroxycitric acid (an ATP-citrate lyase inhibitor). Garcinia cambogia extract lowers the body weight gain, visceral fat accumulation, blood and hepatic lipid concentrations, and plasma insulin and leptin levels in a high-fat diet (HFD)-induced obesity mouse model. Garcinia cambogia extract is promising for research of fatty liver, dyslipidemia, hyperinsulinemia and hyperleptinemia rendered by HFD .
|
-
- HY-N12166
-
|
|
Src
|
Cardiovascular Disease
|
|
2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56 lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease .
|
-
- HY-N6953R
-
|
|
STAT
Keap1-Nrf2
Reactive Oxygen Species
|
Neurological Disease
|
|
Garcinone D (Standard) is the analytical standard of Garcinone D. This product is intended for research and analytical applications. Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration-and time-dependent manners .
|
-
- HY-N6954
-
|
|
ATM/ATR
STAT
CDK
Hedgehog
|
Inflammation/Immunology
Cancer
|
|
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
|
-
- HY-N0941R
-
|
|
Bacterial
Parasite
Apoptosis
|
Infection
Cancer
|
|
beta-Mangostin (Standard) is the analytical standard of beta-Mangostin. This product is intended for research and analytical applications. beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
|
-
- HY-N6954R
-
|
|
ATM/ATR
STAT
CDK
Hedgehog
|
Cancer
|
|
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
|
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N9269
-
-
- HY-N6248
-
-
- HY-N12786
-
-
- HY-N6803
-
-
- HY-N8665
-
-
- HY-N8702
-
-
- HY-N8732
-
-
- HY-N1843
-
-
- HY-N10157
-
-
- HY-N1868
-
-
- HY-N0126
-
-
- HY-N8863
-
-
- HY-N2192
-
-
- HY-N1623
-
-
- HY-N3324
-
-
- HY-N2872
-
-
- HY-N9341
-
-
- HY-N1000
-
-
- HY-N8857
-
-
- HY-N2702
-
-
- HY-N2768
-
-
- HY-N9156
-
-
- HY-N9261
-
-
- HY-N6038
-
-
- HY-N14911
-
-
- HY-N12785
-
-
- HY-114716
-
-
- HY-149373
-
-
- HY-N2000
-
-
- HY-N2192R
-
-
- HY-N3928
-
-
- HY-N15370
-
-
- HY-N8362
-
-
- HY-N6038R
-
-
- HY-N2707
-
-
- HY-N0328
-
-
- HY-N6009
-
-
- HY-N11457
-
-
- HY-N0328R
-
-
- HY-N0985
-
-
- HY-N6953
-
-
- HY-126640
-
|
|
Quinones
Structural Classification
Microorganisms
Anthraquinones
Source classification
|
Parasite
|
|
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
|
-
- HY-N0941
-
-
- HY-N14035
-
|
|
Structural Classification
Natural Products
Guttiferae
Source classification
Garcinia cambogia Desr.
Plants
|
ATP Citrate Lyase
|
|
Garcinia cambogia extract contains several active compounds, including hydroxycitric acid (HCA) (an ECC inhibitor), xanthones, benzophenones, hydroxycitric acid (an ATP-citrate lyase inhibitor). Garcinia cambogia extract lowers the body weight gain, visceral fat accumulation, blood and hepatic lipid concentrations, and plasma insulin and leptin levels in a high-fat diet (HFD)-induced obesity mouse model. Garcinia cambogia extract is promising for research of fatty liver, dyslipidemia, hyperinsulinemia and hyperleptinemia rendered by HFD .
|
-
- HY-N12166
-
|
|
Cardiovascular Disease
Structural Classification
Flavonoids
Microorganisms
Classification of Application Fields
Marine natural products
Source classification
Other Flavonoids
Marine microorganism
Disease Research Fields
|
Src
|
|
2,3,4,6,8-Pentahydroxy-1-methylxanthone is a xanthone derivative of Wardomyces anomalus. 2,3,4,6,8-Pentahydroxy-1-methylxanthone shows significant antioxidant activities. 2,3,4,6,8-Pentahydroxy-1-methylxanthone is inhibitors of p56 lck tyrosine kinase. 2,3,4,6,8-Pentahydroxy-1-methylxanthone can be used to treat cardiovascular disease .
|
-
- HY-N6953R
-
-
- HY-N6954
-
-
- HY-N0941R
-
|
|
Structural Classification
Xanthones
Guttiferae
Source classification
Phenols
Polyphenols
Garcinia mangostana Linn.
Plants
|
Bacterial
Parasite
Apoptosis
|
|
beta-Mangostin (Standard) is the analytical standard of beta-Mangostin. This product is intended for research and analytical applications. beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .
|
-
- HY-N6954R
-
|
|
Structural Classification
other families
Xanthones
Garcinia oblongifolia Champ. ex Benth.
Guttiferae
Source classification
Phenols
Polyphenols
Plants
|
ATM/ATR
STAT
CDK
Hedgehog
|
|
Garcinone C (Standard) is the analytical standard of Garcinone C. This product is intended for research and analytical applications. Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
|
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
