Search Result
Results for "
carbamate
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
18
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Y1401S
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- HY-133776
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3-Nitrophenyl ethyl(methyl)carbamate
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Cholinesterase (ChE)
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Neurological Disease
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Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM, 4.15 μM, respectively .
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- HY-145735
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- HY-W098764
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ADC Linker
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Others
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Allyl (2-aminoethyl)carbamate hydrochloride is a cleavable linker.
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- HY-Y1401R
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Biochemical Assay Reagents
Reference Standards
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Others
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Methyl carbamate (Standard) is the analytical standard of Methyl carbamate. This product is intended for research and analytical applications. Methyl carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W171071
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Biochemical Assay Reagents
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Neurological Disease
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Phenylethynylcarbinol carbamate is a agent used for neurology disease . Phenylethynylcarbinol carbamate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151877S
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- HY-101831
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- HY-170057
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- HY-170736
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- HY-W142194
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DNA/RNA Synthesis
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Cancer
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Benzyl (5-hydroxypentyl)carbamate is a linker capable of repairing damaged DNA by binding to the 5'-hydroxyl group on the sugar backbone. Benzyl (5-hydroxypentyl)carbamate can also bind to DNA ligands and can inhibit cell proliferation in resistant cell lines. However, Benzyl (5-hydroxypentyl)carbamate is toxic to cells and can also cause DNA damage and strand breakage.
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- HY-Y1401
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Biochemical Assay Reagents
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Others
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Methyl carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W722986
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- HY-W097114
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- HY-130482
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- HY-129711
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- HY-138885
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TpGc
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Tyrosinase
DNA/RNA Synthesis
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Neurological Disease
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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine antinociception while preventing the development of tolerance .
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- HY-107944R
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Maolate (Standard); U 19646 (Standard)
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iGluR
Reference Standards
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Neurological Disease
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Chlorphenesin carbamate (Standard) is the analytical standard of Chlorphenesin carbamate. This product is intended for research and analytical applications. Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .
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- HY-107944
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Maolate; U 19646
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Others
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Neurological Disease
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Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .
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- HY-139265
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- HY-B0830
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- HY-W127396
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Biochemical Assay Reagents
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Others
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Cholesteryl N-(trimethylammonioethyl)carbamate chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W819785
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Biochemical Assay Reagents
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Others
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Benzyl (8-hydroxyoctyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W016730S
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- HY-W457953
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Biochemical Assay Reagents
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Others
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tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-40172
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Biochemical Assay Reagents
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Others
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tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B0830S
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- HY-147053
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Others
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Others
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2-(Diethylamino)ethyl (3-(octyloxy)phenyl)carbamate hydrochloride is a small molecule compound.
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- HY-172729
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Biochemical Assay Reagents
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Others
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Phenylmethyl N-(10-bromodecyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-172305
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Biochemical Assay Reagents
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Others
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Phenylmethyl N-(8-bromooctyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-B0830R
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Reference Standards
Cholinesterase (ChE)
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Neurological Disease
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Isoprocarb (Standard) is the analytical standard of Isoprocarb. This product is intended for research and analytical applications. Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor .
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- HY-34346
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[[[Hydrazino]carbonyl]methyl]carbamic acid tert-butyl ester; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate
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Amino Acid Derivatives
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Others
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tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine (HY-Y0966) derivative .
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- HY-22391
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tert-Butyl 2,8-diaminooctanoate
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PROTAC Linkers
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Cancer
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tert-Butyl (7-aminoheptyl)carbamate (tert-Butyl 2,8-diaminooctanoate) is a PROTAC linker. tert-Butyl (7-aminoheptyl)carbamate can be used to synthesis CPD-10 (HY-168660) .
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- HY-121558
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- HY-W591969
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Biochemical Assay Reagents
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Others
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Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
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- HY-W015987
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Fmoc-NH2
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Biochemical Assay Reagents
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Others
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9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes .
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- HY-B1207
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Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-W052066
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Biochemical Assay Reagents
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Others
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tert-Butyl (3-chloropropyl)carbamate is a compound with a t-butyl and a terminal choloride. The cholorine (Cl) is a good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-149037
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N4-Spermine cholesteryl carbamate
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Liposome
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Others
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-153117
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Others
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Others
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Cyclohexyl [3,5-bis(methylthio)-4-isothiazolyl]carbamate is a compound that can be used for altering the lifespan of eukaryotic organisms .
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![Cyclohexyl [3,5-bis(methylthio)-4-isothiazolyl]carbamate](//file.medchemexpress.eu/product_pic/hy-153117.gif)
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- HY-W248726
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Biochemical Assay Reagents
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Others
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tert-Butyl (6-iodohexyl)carbamate is a six carbon linker containing an iodine group and a t-butyl ester. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The t-butyl ester groups can be deprotected under acidic conditions.
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- HY-W598191
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Biochemical Assay Reagents
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Others
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tert-Butyl (3-azidopropyl)carbamate is a reagent containing an azide group and Boc-protected amino group. It is reactive with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W751750
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Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane
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Isotope-Labeled Compounds
Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane- 13C, 15N (Ethyl carbamate- 13C, 15N) is the 13C- and 15N-labeled Urethane (HY-B1207). Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-W092078
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Biochemical Assay Reagents
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Others
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tert-Butyl (4-iodobutyl)carbamate is a four carbon linker containing a Boc-protected amino group and an iodine group. The Boc group can be deprotected under mild acidic conditions to form the free amine. Iodine (I) is a very good leaving group for nucleophilic substitution reactions.
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- HY-117695
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AQC
3 Publications Verification
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
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Fluorescent Dye
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Others
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AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
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- HY-149037A
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N4-Spermine cholesteryl carbamate pentahydrochloride
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Liposome
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Others
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GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-42773
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1-Boc-1,8-diaminooctane
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PROTAC Linkers
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Cancer
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tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W088456
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PROTAC Linkers
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Cancer
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tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate is a linker that can be used for synthesis of PROTAC degrader TrimTAC1 (HY-169355) .
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![tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate](//file.medchemexpress.eu/product_pic/hy-w088456.gif)
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- HY-W101722
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PROTAC Linkers
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Cancer
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tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W047688
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1-Boc-1,10-diaminodecane
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PROTAC Linkers
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Cancer
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tert-Butyl (10-aminodecyl)carbamate (1-Boc-1,10-diaminodecane) can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. tert-Butyl (10-aminodecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-156513
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7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)
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ADC Cytotoxin
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Cancer
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ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin (HY-16560) analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRα-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research .
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- HY-119419
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Cholinesterase (ChE)
Parasite
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Neurological Disease
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Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
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- HY-119360
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Insecticide
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Others
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Lilly 18947 (free base) is a selective drug-potentiating agent that synergizes carbamate insecticides. Lilly 18947 (free base) inhibits a variety of detoxication mechanisms in mammals .
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- HY-30120
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Biochemical Assay Reagents
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Others
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tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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![tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate](//file.medchemexpress.eu/product_pic/hy-30120.gif)
- HY-20240
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PROTAC Linkers
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Cancer
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tert-Butyl (6-aminospiro[3.3]heptan-2-yl)carbamate is a linker that can be used for synthesis of PROTAC degrader CPD-39 (HY-168664) .
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![tert-Butyl (6-aminospiro[3.3]heptan-2-yl)carbamate](//file.medchemexpress.eu/product_pic/hy-20240.gif)
- HY-122832
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Wnt
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Cancer
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ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM .
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- HY-W751753
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N-Cyanoacetylurethane-13C3,15N
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Isotope-Labeled Compounds
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Others
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Ethyl (2-cyanoacetyl)carbamate- 13C3, 15N (N-Cyanoacetylurethane- 13C3, 15N) is the 13C- and 15N-labeled Ethyl (2-cyanoacetyl)carbamate (HY-W001933).
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- HY-W578278
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-(pyridin-2-yldisulfanyl)ethyl)carbamate consists of a tert-butyl group, where the protected amine can be deprotected under mild acidic conditions, and the other part of the molecule may act as a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins.
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- HY-B1207R
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Ethyl carbamate (Standard); Carbamic acid ethyl ester (Standard); Ethylurethane (Standard)
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Reference Standards
Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-W460133
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is a PEG linker containing a Boc protected amine and an iodine group. The protected amine can be deprotected under mild acidic conditions. Iodine (I) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-119419R
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Reference Standards
Cholinesterase (ChE)
Parasite
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Neurological Disease
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Pirimicarb (Standard) is the analytical standard of Pirimicarb. This product is intended for research and analytical applications. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
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- HY-W190911
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Biochemical Assay Reagents
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Others
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Cyclooct-4-en-1-yl(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate is commonly used in Click Chemistry reactions. The hydroxyl group allows for additional reactions to take place to further derivatize the compound.
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- HY-W800833
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Biochemical Assay Reagents
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Others
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Benzyl N-[2-(prop-2-enamido)ethyl]carbamate is a short aliphatic linker featuring a Cbz-protected amine and an acrylamide. Acrylamide is a Michael acceptor which is a good Michael acceptor which can be used in thiol-based bioconjugation or polymerization. Meanwhile, the Cbz protecting group can be removed using Pd-C hydrogenation to reveal a free amine that can participate in a wide variety of reactions such as couplings or reductive amination.
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![Benzyl N-[2-(prop-2-enamido)ethyl]carbamate](//file.medchemexpress.eu/product_pic/hy-w800833.gif)
- HY-173381
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Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate
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Biochemical Assay Reagents
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Others
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Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid product. Cholesteryl-PEG2000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG2000-Biotin can be used for drug circulation time studies .
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- HY-143419
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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ATX inhibitor 14 (compound 4), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 0.41 nM. ATX inhibitor 14 has the potential for fibrosis relevant diseases research .
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- HY-B0835S
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Isotope-Labeled Compounds
Apoptosis
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Neurological Disease
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Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis .
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- HY-B1207S
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Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
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Bacterial
Parasite
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Infection
Neurological Disease
Cancer
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Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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- HY-143420
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Phosphodiesterase (PDE)
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Inflammation/Immunology
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ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model .
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- HY-401269
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-(4-(2-(5-(3,5-dimethylisoxazol-4-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)phenoxy)ethyl)carbamate is a biological molecule.
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![tert-Butyl (2-(4-(2-(5-(3,5-dimethylisoxazol-4-yl)-1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)ethyl)phenoxy)ethyl)carbamate](//file.medchemexpress.eu/product_pic/hy-401269.gif)
- HY-D1258
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VDP-green
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Fluorescent Dye
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Others
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AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
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- HY-B2032
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- HY-153804
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NCD
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Molecular Glues
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Others
Cancer
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Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functional DNA to modulate function .
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- HY-117870
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- HY-W059342S
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- HY-18080
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- HY-E70572
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- HY-121267S1
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- HY-B2032R
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Herbicide
Reference Standards
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Others
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Phenmedipham (Standard) is the analytical standard of Phenmedipham. This product is intended for research and analytical applications. Phenmedipham is a carbamate herbicide .
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- HY-B2032S
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- HY-N3162
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Others
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Others
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Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .
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- HY-W800763
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- HY-111202
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- HY-17530
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- HY-N9349
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- HY-139143
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FAAH
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Others
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WWL154, an analog of JZL184 that maintains the SH-reactive p-nitrophenyl carbamate group, is a FAAH-4 inhibitor .
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- HY-W014240
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Herbicide
Mitosis
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Others
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Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
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- HY-42780
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Ligands for E3 Ligase
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Cancer
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Thalidomide-O-amido-C8-NHBoc contains a Thalidomide group, an amide, an alkylC8 chain, and a carbamate protecting group.
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- HY-40174A
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Biochemical Assay Reagents
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Others
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tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W131541
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PROTAC Linkers
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Cancer
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tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W714025S
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- HY-W037331
-
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Bis(4-fluorophenyl)methanol
|
mAChR
|
Others
|
|
4,4-Difluorobenzhydrol is a precursor of a mAChR antagonist, and its derivative 4,4-Difluorobenzhydrol Carbamate can selectively target the M1 subtype .
|
-
- HY-W013767
-
|
|
Insecticide
|
Infection
|
|
Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile .
|
-
- HY-173381A
-
|
Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate
|
Biochemical Assay Reagents
|
Others
|
|
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .
|
-
- HY-W800830
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-Nitrophenyl Carbonate is a short reagent featuring a DMG lipid headgroup and a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions.
|
-
- HY-116482
-
|
|
Herbicide
|
Others
|
|
Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction .
|
-
- HY-23020
-
|
|
Proteasome
|
Cancer
|
|
Boc3Arg is the tert-butyl carbamate-protected arginine. Boc3Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome .
|
-
- HY-W321016S
-
-
- HY-W021597
-
|
|
Drug Intermediate
|
Others
|
|
N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination .
|
-
- HY-W002421
-
|
|
Biochemical Assay Reagents
|
Others
|
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-110178
-
|
|
MAGL
|
Inflammation/Immunology
|
|
WWL123, a carbamate-based compound, is a potent and selective ABHD6 inhibitor. WWL123 can be used for research of inflammation, metabolic disorders (obesity and type II diabetes mellitus) and epilepsy .
|
-
- HY-W014240S1
-
|
|
Isotope-Labeled Compounds
Mitosis
|
Others
|
|
Chlorpropham-d7 is the deuterium labeled Chlorpropham . Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
|
-
- HY-B0835
-
|
|
Apoptosis
|
Cardiovascular Disease
Neurological Disease
|
|
Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals .
|
-
- HY-W014240R
-
|
|
Herbicide
Mitosis
Reference Standards
|
Others
|
|
Chlorpropham (Standard) is the analytical standard of Chlorpropham. This product is intended for research and analytical applications. Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
|
-
- HY-P2331
-
|
Antibiotic A 3802-IV-3; Gardimycin
|
Antibiotic
|
Infection
|
|
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
|
-
- HY-17530R
-
|
|
Reference Standards
Cholinesterase (ChE)
Parasite
Drug Metabolite
|
Infection
|
|
Aldicarb sulfone (Standard) is the analytical standard of Aldicarb sulfone (HY-17530). This product is intended for research and analytical applications. Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase.
|
-
- HY-119419S
-
|
|
Cholinesterase (ChE)
Parasite
Isotope-Labeled Compounds
|
Others
|
|
Pirimicarb-d6 is the deuterium labeled Pirimicarb (HY-119419). Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
|
-
- HY-W013767R
-
|
|
Insecticide
Reference Standards
|
Infection
|
|
Thiodicarb (Standard) is the analytical standard of Thiodicarb. This product is intended for research and analytical applications. Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile .
|
-
- HY-172511
-
|
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG9-4-nitrophenyl carbonate serves as a PEG linker containing a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions. The PEG9 chain bolsters the water solublity of the compound.
|
-
- HY-116482R
-
|
|
Insecticide
Herbicide
Reference Standards
|
Others
|
|
Desmedipham (Standard) is the analytical standard of Desmedipham. This product is intended for research and analytical applications. Desmedipham is a selective systemic phenyl-carbamate herbicide. Desmedipham acts by disrupting CO2 fixation and the production of intermediary energy components-ATP and NADPH2 and inhibition of Hill reaction .
|
-
- HY-103522
-
|
|
GABA Receptor
|
Neurological Disease
|
|
AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases .
|
-
- HY-17530S
-
-
- HY-B0835R
-
|
|
Reference Standards
Apoptosis
|
Cardiovascular Disease
Neurological Disease
|
|
Fenobucarb (Standard) is the analytical standard of Fenobucarb. This product is intended for research and analytical applications. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals .
|
-
- HY-P2831
-
|
CESs
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
|
-
- HY-79513
-
|
tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
|
Amino Acid Derivatives
|
Others
|
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
|
-
- HY-P1726
-
-
- HY-P1726A
-
|
|
Melanocortin Receptor
|
Cancer
|
|
MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
|
-
- HY-W728451
-
|
|
FAAH
|
Cardiovascular Disease
Neurological Disease
|
|
URB694 is a carbamate FAAH inhibitor that irreversibly carbamoylate the nucleophile catalytic serine in FAAH active site. URB694 exhibits antidepressant-like activity and cardioprotective effects. URB694 can be used to prepare 11C-Carbonyl-URB694 for in vivo positron emission tomography (PET) imaging studies of the brain FAAH .
|
-
- HY-144689
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
BChE-IN-3 (compound 45a) is a potent, selective, time-dependent and pseudoirreversible BChE inhibitor, with an IC50 of 56.9 nM. BChE-IN-3 also shows marginal and reversible (not time-dependent) inhibition of AChE .
|
-
- HY-128035
-
|
|
Phospholipase
MAGL
|
Cardiovascular Disease
|
|
ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases .
|
-
- HY-B2041
-
|
|
Insecticide
|
Infection
|
|
Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development .
|
-
- HY-W099331R
-
|
MEGX hydrochloride (Standard); Norlidocaine hydrochloride (Standard)
|
Reference Standards
Drug Metabolite
|
Metabolic Disease
Inflammation/Immunology
|
|
Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development .
|
-
- HY-B2041R
-
|
|
Parasite
Reference Standards
|
Infection
|
|
Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development .
|
-
- HY-146436
-
|
|
Angiotensin Receptor
|
Others
|
|
AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. AT1R antagonist 2 exhibits a fair AT1R affinity, with a Ki of 26 nM .
|
-
- HY-146431
-
|
|
Angiotensin Receptor
|
Others
|
|
AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand. AT1R antagonist 1 exhibits a fair AT1R affinity, with a Ki of 8.5 nM .
|
-
- HY-P0041A
-
-
- HY-P0041
-
-
- HY-169355
-
|
|
PROTACs
|
Cancer
|
|
TrimTAC1 is a PROTAC degrader that selectively targets the degradation of the multimeric protein Nucleoporin . TrimTAC1 is composed of PROTAC target protein ligand (red part) (+)-JQ-1 (HY-13030), E3 ligase ligand (blue part) Acepromazine-OTs (HY-169356) and PROTAC linker (black part) tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate (HY-W088456). Among them, its E3 ligase ligand + linker can form Acepromazine-1-Piperazinepropanamine (HY-169357).
|
-
- HY-146314
-
|
|
Monoamine Oxidase
Amyloid-β
|
Neurological Disease
|
|
MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-B0916
-
|
|
Insecticide
Cholinesterase (ChE)
MMP
Reactive Oxygen Species (ROS)
ERK
Keap1-Nrf2
|
Infection
Neurological Disease
Cancer
|
|
Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests .
|
-
- HY-146313
-
|
|
Cholinesterase (ChE)
|
Neurological Disease
|
|
BChE-IN-7 (compound 13) is a potent, selective, BBB-penetrated and reversible AChE and BChE inhibitor, with an IC50 of 0.06 μM (BChE). BChE-IN-7 can protect neuronal-like cells from toxic Aβ-species .
|
-
- HY-146427
-
|
|
Fungal
|
Infection
|
|
Antifungal agent 29 (compound 9d) is a potent, selective and non-toxic antifungal agent. Antifungal agent 29 shows antifungal activity towards Cryptococcus neoformans (MIC ≤ 0.23 μM) .
|
-
- HY-B0916S
-
|
|
Isotope-Labeled Compounds
Insecticide
Cholinesterase (ChE)
MMP
Reactive Oxygen Species (ROS)
ERK
Keap1-Nrf2
|
Infection
Neurological Disease
Cancer
|
|
Propoxur-d3 is the deuterated form of Propoxur (HY-B0916). Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests .
|
-
- HY-B0916R
-
|
|
Reference Standards
MMP
Insecticide
Cholinesterase (ChE)
Reactive Oxygen Species (ROS)
ERK
Keap1-Nrf2
|
Infection
Neurological Disease
Cancer
|
|
Propoxue (Standard) is the analytical standard of Propoxue (HY-B0916). This product is intended for research and analytical applications. Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-117695
-
AQC
3 Publications Verification
6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
|
Fluorescent Dyes/Probes
|
|
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels .
|
-
- HY-D1258
-
|
VDP-green
|
Fluorescent Dyes/Probes
|
AC-green (VDP-green) is a β-allyl carbamate fluorescent probe for specifically imaging vicinal dithiol proteins (VDPs) in living systems (λex/λem=400/475 nm). AC-green can detect the reduced bovine serum albumin (rBSA) with high sensitivity. AC-green displays low toxicity and features high sensitivity, and is suitable for sensing VDPs in living cells and zebrafishes .
|
| Cat. No. |
Product Name |
Type |
-
- HY-Y1401
-
|
|
Biochemical Assay Reagents
|
|
Methyl carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-40172
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-149037A
-
|
N4-Spermine cholesteryl carbamate pentahydrochloride
|
Drug Delivery
|
|
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-30120
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl N-[(1S,2S)-2-aminocyclohexyl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-40174A
-
|
|
Biochemical Assay Reagents
|
|
tert-Butyl (2-aminoethyl)(methyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y1401R
-
|
|
Biochemical Assay Reagents
|
|
Methyl carbamate (Standard) is the analytical standard of Methyl carbamate. This product is intended for research and analytical applications. Methyl carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W097114
-
|
|
Carbohydrates
|
|
Benzyl (6-bromohexyl)carbamate can be used in glycobiology research.
|
-
- HY-W127396
-
|
|
Biochemical Assay Reagents
|
|
Cholesteryl N-(trimethylammonioethyl)carbamate chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-149037
-
|
N4-Spermine cholesteryl carbamate
|
Drug Delivery
|
|
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-173381
-
|
Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate
|
Drug Delivery
|
|
Cholesteryl-PEG2000-Biotin (Cholesteryl biotinyl(polyethyleneglycol)-2000 carbamate) is a lipid product. Cholesteryl-PEG2000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG2000-Biotin can be used for drug circulation time studies .
|
-
- HY-173381A
-
|
Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate
|
Drug Delivery
|
|
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .
|
-
- HY-W002421
-
|
|
Biochemical Assay Reagents
|
|
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-34346
-
|
[[[Hydrazino]carbonyl]methyl]carbamic acid tert-butyl ester; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate
|
Amino Acid Derivatives
|
Others
|
|
tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine (HY-Y0966) derivative .
|
-
- HY-W015987
-
|
Fmoc-NH2
|
Biochemical Assay Reagents
|
Others
|
|
9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes .
|
-
- HY-79513
-
|
tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
|
Amino Acid Derivatives
|
Others
|
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
|
-
- HY-P0041A
-
-
- HY-P2331
-
|
Antibiotic A 3802-IV-3; Gardimycin
|
Antibiotic
|
Infection
|
|
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
|
-
- HY-P10014
-
-
- HY-P1726A
-
|
|
Melanocortin Receptor
|
Cancer
|
|
MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 TFA also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 TFA exhibits binding affinity for A375 melanoma cells in vitro. MSG606 TFA reverses the induced hyperalgesia in female mice, with no effect in male mice.
|
-
- HY-P0041
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-Y1401S
-
|
|
|
Methyl carbamate-d3 is the deuterium labeled Methyl carbamate .
|
-
-
- HY-B1207S
-
|
|
|
Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
|
-
-
- HY-W059342S
-
|
|
|
Etoxazole-d5 is the deuterium labeled Phenmedipham. Phenmedipham is a carbamate herbicide .
|
-
-
- HY-151877S
-
|
|
|
Ethyl N-n-Butyl-d9-carbamate is the deuterium labeled Ethyl N-n-Butyl-carbamate .
|
-
-
- HY-W722986
-
|
|
|
tert-Butyl ethyl(isopropyl)carbamate-d5 is the deuterium labeled tert-Butyl ethyl(isopropyl)carbamate.
|
-
-
- HY-W016730S
-
|
|
|
tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6 is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate .
|
-
-
- HY-B0830S
-
|
|
|
Isoprocarb-d3 is deuterium labeled Isoprocarb. Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor .
|
-
-
- HY-W751750
-
|
|
|
Urethane- 13C, 15N (Ethyl carbamate- 13C, 15N) is the 13C- and 15N-labeled Urethane (HY-B1207). Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
|
-
-
- HY-W751753
-
|
|
|
Ethyl (2-cyanoacetyl)carbamate- 13C3, 15N (N-Cyanoacetylurethane- 13C3, 15N) is the 13C- and 15N-labeled Ethyl (2-cyanoacetyl)carbamate (HY-W001933).
|
-
-
- HY-B0835S
-
|
|
|
Fenobucarb-d3 is the deuterium labeled Fenobucarb. Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis .
|
-
-
- HY-121267S1
-
|
|
|
Dicamba-d3 is the deuterium labeled Methyl (3,4-dichlorophenyl)carbamate .
|
-
-
- HY-B2032S
-
|
|
|
Phenmedipham-d3 is the deuterium labeled Phenmedipham (HY-B2032). Phenmedipham is a carbamate herbicide .
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-
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- HY-W714025S
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4-Hydroxychlorpropham-d7 is the deuterium labeled Isopropyl (3-chloro-4-hydroxyphenyl)carbamate (HY-W714025).
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- HY-W321016S
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SWEP-d3 is the deuterium labeled Fmoc-Tyr(tBu)-OH .
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- HY-W014240S1
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Chlorpropham-d7 is the deuterium labeled Chlorpropham . Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules .
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- HY-119419S
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Pirimicarb-d6 is the deuterium labeled Pirimicarb (HY-119419). Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide .
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- HY-17530S
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Aldicarb sulfone- 13C2,d3 is the deuterium and 13C labeled Aldicarb sulfone (HY-17530). Aldicarb sulfone is one of the metabolites of the carbamate pesticide Aldicarb and has insecticidal activity. Aldicarb sulfone is also an inhibitor of cholinesterase .
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- HY-B0916S
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Propoxur-d3 is the deuterated form of Propoxur (HY-B0916). Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests .
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- HY-W457953
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Azide
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tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-146314
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Alkynes
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MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W171071
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Alkynes
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Phenylethynylcarbinol carbamate is a agent used for neurology disease . Phenylethynylcarbinol carbamate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-149037A
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N4-Spermine cholesteryl carbamate pentahydrochloride
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Cationic Lipids
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GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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- HY-149037
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N4-Spermine cholesteryl carbamate
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Cationic Lipids
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
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