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hair

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77

Inhibitors & Agonists

1

Fluorescent Dye

16

Biochemical Assay Reagents

13

Peptides

12

Natural
Products

1

Recombinant Proteins

4

Isotope-Labeled Compounds

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18673

    Biochemical Assay Reagents Others
    PROTO-1 is a hair cell protector and can be used in studies of ototoxicity-induced hair cell death .
    PROTO-1
  • HY-10561

    PSK-3841; HMR-3841

    Androgen Receptor Endocrinology
    RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth .
    RU 58841
  • HY-139783

    Apoptosis Others
    3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS) .
    3-Campholenyl-2-butanol
  • HY-B1445

    Potassium Channel Metabolic Disease
    Minoxidil sulfate, a potent and ATP-sensitive K + channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo .
    Minoxidil sulfate
  • HY-50856S

    CTP-543; Ruxolitinib d8; Deuterated Ruxolitinib

    JAK Inflammation/Immunology
    Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), is an orally active JAK1 and JAK2 inhibitor. Deuruxolitinib demonstrates significant hair regrowth effects. Deuruxolitinib can be used for the research of alopecia areata .
    Deuruxolitinib
  • HY-167655

    Androgen Receptor Others
    KF-19418 is an anti-androgen antisense oligonucleotide (ASO) and a hair follicle stimulator. KF-19418 directly stimulated hair follicle in vitro and has hair growth promoting activities in vivo .
    KF-19418
  • HY-160692

    Androgen Receptor Others
    AR antagonist 7 (86) is an androgen receptor (AR) antagonist that can be used in the research of hair loss .
    AR antagonist 7
  • HY-P5258

    EGFR Metabolic Disease
    Oligopeptide-41 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
    Oligopeptide-41
  • HY-129677

    TRP Channel Others
    ORC-13661 hydrochloride is a hair cell protector. ORC-13661 hydrochloride protects sensory hair cells from aminoglycoside and Cisplatin (HY-17394) ototoxicity. ORC-13661 hydrochloride is a reversibly mechanoelectrical transducer (MET) channel permeant blocker .
    ORC-13661 hydrochloride
  • HY-W108953

    TGF-beta/Smad Metabolic Disease
    Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes .
    Myristoyl tetrapeptide-12
  • HY-163506

    Apoptosis Ferroptosis Others
    Ebselen derivative 1 (Compound 19) is a glutathione peroxidase (GPx) mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin (HY-17394)-induced hearing loss .
    Ebselen derivative 1
  • HY-W009001

    Biochemical Assay Reagents Drug Derivative Others
    Cholesteryl chloride is an organochloride derivative of Cholesterol (HY-N0322). Cholesteryl chloride can be used in some hair colors, make-ups, and some other cosmetic preparations .
    Cholesteryl chloride
  • HY-N0322A
    Cholesterol (Water Soluble)
    Maximum Cited Publications
    41 Publications Verification

    Liposome Others
    Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .
    Cholesterol (Water Soluble)
  • HY-149296

    JAK Inflammation/Immunology
    JAK1-IN-12 is a selective inhibitor of JAK1, with IC50 of 0.0246 μM. And IC50s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2, JAK3 and TYK2. JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases .
    JAK1-IN-12
  • HY-116198

    15-PGDH Metabolic Disease
    15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC50 value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .
    15-PGDH-IN-2
  • HY-N0036
    Costunolide
    5+ Cited Publications

    (+)-Costunolide; Costus lactone

    Apoptosis Endogenous Metabolite Cancer
    Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells .
    Costunolide
  • HY-N0036R

    Apoptosis Endogenous Metabolite Cancer
    Costunolide (Standard) is the analytical standard of Costunolide. This product is intended for research and analytical applications. Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells .
    Costunolide (Standard)
  • HY-109102

    TS-133

    FKBP Others
    Setafrastat (Compound 40) is a hair growth stimulator .
    Setafrastat
  • HY-162831

    Mitochondrial Metabolism Others
    MPC-IN-1 (compound 4i) is a cyanocinnamate-based, mitochondrial pyruvate transporter (MPC) inhibitor, and is a derivative of UK-5099 (HY-15475). MPC inhibitors promote the development of hair follicle stem cells without affecting normal cells. MPC-IN-1 promotes cellular lactate production and promotes significant hair growth in mice, and has the potential to be used to inhibit hair loss .
    MPC-IN-1
  • HY-W009081

    Endogenous Metabolite Metabolic Disease
    Tricosanoic acid is a long-chain fatty acid and shown to be a hair growth stimulant.
    Tricosanoic acid
  • HY-P5247

    PTP20

    Melanocortin Receptor Metabolic Disease Inflammation/Immunology
    Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide that is an agonist for α-MSH. Palmitoyl tetrapeptide-20 can protect follicular melanocytes and activate melanogenesis by enhancing catalase expression .
    Palmitoyl tetrapeptide-20
  • HY-W012081

    Biochemical Assay Reagents Others
    2,4-Diaminophenoxyethanol dihydrochloride is an oxidation colorant used in hair dyes .
    2,4-Diaminophenoxyethanol dihydrochloride
  • HY-P5253

    Reactive Oxygen Species Metabolic Disease
    Octapeptide-2 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .
    Octapeptide-2
  • HY-B0744
    Eflornithine
    10+ Cited Publications

    DFMO; MDL71782; RMI71782; α-difluoromethylornithine

    Parasite Infection Cancer
    Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine
  • HY-B0744A
    Eflornithine hydrochloride
    10+ Cited Publications

    DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride

    Parasite Infection Cancer
    Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
    Eflornithine hydrochloride
  • HY-B0744B

    DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate

    Parasite Cancer
    Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
    Eflornithine hydrochloride hydrate
  • HY-W108953A

    TGF-beta/Smad Others
    Myristoyl tetrapeptide-12 dihydrochloride is a peptide containing lysine and alanin. Myristoyl tetrapeptide-12 dihydrochloride is utilized as hair cair preparations agent in cosmetics industry .
    Myristoyl tetrapeptide-12 dihydrochloride
  • HY-N7229

    DNA/RNA Synthesis Cancer
    Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings .
    Rabdosin B
  • HY-B1024

    DL-Pantothenol; DL-Pantothenyl alcohol

    Biochemical Assay Reagents Others
    DL-Panthenol (DL-Pantothenol) is an alcohol derivative of pantothenyl acid. DL-Panthenol exerts eyelash protection effect. DL-Panthenol is widely used in the Skin and hair conditioner research .
    DL-Panthenol
  • HY-B0612B

    Calcium Channel Sodium Channel Neurological Disease
    (S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism .
    (S)-Lercanidipine
  • HY-137680

    Diguanoside tetraphosphate

    Endogenous Metabolite Others
    GP4G (Diguanoside tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator .
    GP4G
  • HY-B0704S

    Nonanedioic acid-d14

    Endogenous Metabolite Others
    Azelaic acid-d14 is the deuterium labeled Azelaic acid[1]. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners[2][3].
    Azelaic acid-d14
  • HY-N12938

    Others Endocrinology
    (Z)-7-Hexadecenyl acetate is a pheromone used for capturing male tobacco budworm moths (Heliothis virescens), which can be isolated from the brush glands or hair pencils on the abdomen or hind wings of insects .
    (Z)-7-Hexadecenyl acetate
  • HY-170448

    PROTACs Androgen Receptor Endocrinology
    PROTAC AR Degrader-9 (Compound c6) is a PROTAC degrader for androgen receptor, that degrades AR in human hair follicle papilla cells (HDPCs) with a DC50 of 262.38 nM. PROTAC AR Degrader-9 promotes the expressions of paracrine factors, such as TGF-β1 and β-catenin, exhibits hair regenerating efficacy in mouse models . (Pink: ligand for target protein AR ligand-38 (HY-170450); Black: linker; Blue: ligand for E3 ligase Cereblon (HY-170449))
    PROTAC AR Degrader-9
  • HY-W129441

    N-Ac-4-S-CAP

    DNA/RNA Synthesis Tyrosinase Thymidylate Synthase Others
    N-Acetyl-4-S-mercaptoaminophenol (N-Ac-4-S-CAP) is a compound that is selectively cytotoxic to melanocytes of black mouse hair follicles. It can cause 98% depigmentation of black mouse hair follicles. N-Ac-4-S-CAP can produce visible changes in hair follicle melanocytes 4 hours after intraperitoneal injection, including aggregation of melanin granules and nuclear condensation. Electron microscopy observations showed that it caused progressive destruction of melanocytes, including swelling of membranous organelles, nuclear condensation, and cytoplasmic vacuolation, ultimately leading to complete cell necrosis. N-Ac-4-S-CAP has a specific cytotoxic effect on melanocytes that actively produce eumelanin, but may not affect precursor or dormant melanocytes. These properties suggest that N-Ac-4-S-CAP may have potential application value in the treatment of melanoma or skin whitening.
    N-Acetyl-4-S-cysteaminylphenol
  • HY-B0744BR

    Parasite Cancer
    Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
    Eflornithine (hydrochloride hydrate) (Standard)
  • HY-10445

    Azoline; R126638

    Fungal Infection
    Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
    Pramiconazole
  • HY-W127565

    Biochemical Assay Reagents Others
    HexatetracontaneIt is an organic compound belonging to hydrocarbons. It has a high melting point. HexatetracontaneIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and humectant in skin and hair care products. In addition, it is used as a lubricant and coating agent in industrial environments.
    Hexatetracontane
  • HY-B0112
    Minoxidil
    5+ Cited Publications

    U10858

    Potassium Channel Endogenous Metabolite Cardiovascular Disease Cancer
    Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .
    Minoxidil
  • HY-W127549

    cis-6-Octadecenoic acid

    Biochemical Assay Reagents Others
    Petroselinic acid sodium is an organic compound belonging to the class of carboxylic acids. Petroselinic acid sodium has several applications in the cosmetic and personal care industries, especially as an emulsifier and conditioning agent in skin and hair care products. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.
    Petroselinic acid sodium
  • HY-158012

    γ-secretase Others
    LY3056480 is a gamma-secretase inhibitor (GSI) that inhibits Notch signaling. LY3056480 improves mild to moderate sensorineural hearing loss and is safe and tolerable. Intratympanic administration of LY3056480 induces hair cell regeneration and partial hearing recovery in mammals .
    LY3056480
  • HY-135057

    Lauramidopropyl betaine

    Biochemical Assay Reagents Others
    Lauroylamide propylbetaine (35% in water) (Lauramidopropyl betaine) is an ampholytic surfactant for cosmetic and hair compositions to enhance viscosity and has good biodegradability. Lauroylamide propylbetaine (35% in water) promotes CH4 hydrate formation by reducing the induction time and increasing the CH4 consumption rate for hydrate growth .
    Lauroylamide propylbetaine (35% in water)
  • HY-W127338

    Biochemical Assay Reagents Others
    Butyl Palmitate is an ester compound commonly used as a conditioning, emollient or fragrance in a variety of cosmetic and personal care products. In addition, it can be used as a solvent or lubricant in various industrial applications. Its unique chemical properties make it an important ingredient in a variety of commercial products, including perfumes, lotions and hair care products.
    Butyl Palmitate
  • HY-W127540

    Hexadecyl acetate

    Biochemical Assay Reagents Others
    Palmityl acetate is an ester compound with a waxy odor commonly used as a lubricant or emollient in various cosmetic and personal care products. In addition, it can be used as a plasticizer or stabilizer in the production of plastics and resins. Its unique chemical properties make it an important ingredient in a variety of commercial products, including perfumes, lotions and hair care products.
    Palmityl acetate
  • HY-W127534

    Trihexanoin

    Biochemical Assay Reagents Others
    TricaproinIt is an organic compound belonging to the class of triacylglycerols. It consists of three molecules of caproic acid esterified to the glycerin backbone, with a mild fatty smell. TricaproinIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and conditioning agent in skin and hair care products. Additionally, it is used as a lubricant and surfactant in industrial settings.
    Tricaproin
  • HY-W127377

    Biochemical Assay Reagents Others
    Butyl oleateIt is an organic compound belonging to esters. It is formed from the reaction of butanol and oleic acid and has a mild fruity smell. Butyl oleateIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and conditioning agent in skin and hair care products. Additionally, it is used as a lubricant and solvent in industrial settings.
    Butyl oleate
  • HY-W127506

    Biochemical Assay Reagents Others
    TrielaidinIt is an organic compound belonging to the class of triacylglycerols. It consists of three molecules of elaidic acid esterified to the glycerin backbone, with a mild fatty smell. TrieladinIt has a variety of applications in the cosmetic and personal care industries, especially as an emollient and conditioning agent in skin and hair care products. Additionally, it is used as a lubricant and surfactant in industrial settings.
    Trielaidin
  • HY-W250580

    Biochemical Assay Reagents Others
    Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products .
    Dimethicone
  • HY-N2086S

    Ethyl hexadecanoate-d31

    Isotope-Labeled Compounds Others
    Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
    Ethyl palmitate-d31
  • HY-18237

    Src Others
    KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL) .
    KX1-004

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