2. Immunology/Inflammation
  3. FAP
  4. 3BP-3940

3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment.

For research use only. We do not sell to patients.

3BP-3940 Chemical Structure

3BP-3940 Chemical Structure

CAS No. : 2803421-14-7

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3BP-3940 Related Antibodies

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Description

3BP-3940 is a highly potent fibroblast activation protein (FAP)-targeting peptide for theranostics. 3BP-3940 is often coupled with radionuclides for tumor diagnosis and treatment[1].

Molecular Weight

1471.76

Formula

C66H98N14O18S3
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

nBu-CAyl-{Cys(tMeBn(DOTA-AET)-Pro-Pro-Thr-GIn-Phe-Cys}-OH
Sequence Shortening

nBu-CAyl-{Cys(tMeBn(DOTA-AET)-PPTQFC}-OH
SMILES

O=C1[C@@]2([H])N(CCC2)C([C@H](CSCC3=CC(CSCCNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=CC(CSC[C@H](NC([C@@H](NC([C@@H](NC([C@](NC([C@@]5([H])N1CCC5)=O)([H])[C@H](O)C)=O)CCC(N)=O)=O)CC6=CC=CC=C6)=O)C(O)=O)=C3)NC(NCCCC)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (67.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6795 mL 3.3973 mL 6.7946 mL
5 mM 0.1359 mL 0.6795 mL 1.3589 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6795 mL 3.3973 mL 6.7946 mL 16.9865 mL
5 mM 0.1359 mL 0.6795 mL 1.3589 mL 3.3973 mL
10 mM 0.0679 mL 0.3397 mL 0.6795 mL 1.6986 mL
15 mM 0.0453 mL 0.2265 mL 0.4530 mL 1.1324 mL
20 mM 0.0340 mL 0.1699 mL 0.3397 mL 0.8493 mL
25 mM 0.0272 mL 0.1359 mL 0.2718 mL 0.6795 mL
30 mM 0.0226 mL 0.1132 mL 0.2265 mL 0.5662 mL
40 mM 0.0170 mL 0.0849 mL 0.1699 mL 0.4247 mL
50 mM 0.0136 mL 0.0679 mL 0.1359 mL 0.3397 mL
60 mM 0.0113 mL 0.0566 mL 0.1132 mL 0.2831 mL
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3BP-3940 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3BP-39402803421-14-7FAPFibroblast activation proteinInhibitorinhibitorinhibit

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