TBC1D7-LOC100130357 - TBC1D7-LOC100130357 readthrough Gene

Homo sapiens (human)

Gene ID: 107080638 | Gene type: protein coding

About TBC1D7-LOC100130357

Summary

This locus represents naturally occurring readthrough transcription between the neighboring TBC1D7 (TBC1 domain family member 7) gene and downstream uncharacterized LOC100130357 on chromosome 6. Readthrough transcripts may encode the same protein as TBC1 domain family member 7 or may be candidates for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Jan 2016]

TBC1D7-LOC100130357 Products(1)

mRNA	Protein	Name
NR_134872.2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTPase activator activity	IDA IDA: Inferred from direct assay	17646400	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	17658474	GOA
enables small GTPase binding	IPI IPI: Inferred from physical interaction	17646400	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in activation of GTPase activity	IMP IMP: Inferred from mutant phenotype	22795129	GOA
involved in cellular response to starvation	IDA IDA: Inferred from direct assay	24529379	GOA
involved in negative regulation of TOR signaling	IDA IDA: Inferred from direct assay	22795129	GOA
involved in negative regulation of TOR signaling	IMP IMP: Inferred from mutant phenotype	22795129	GOA
involved in negative regulation of TORC1 signaling	IDA IDA: Inferred from direct assay	24529379	GOA
involved in negative regulation of cilium assembly	IMP IMP: Inferred from mutant phenotype	17646400	GOA
involved in positive regulation of GTPase activity	IDA IDA: Inferred from direct assay	17646400	GOA
involved in positive regulation of protein ubiquitination	IDA IDA: Inferred from direct assay	17658474	GOA
involved in response to growth factor	IMP IMP: Inferred from mutant phenotype	22795129	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of TSC1-TSC2 complex	IDA IDA: Inferred from direct assay	24529379	GOA
part of TSC1-TSC2 complex	IPI IPI: Inferred from physical interaction	22795129	GOA
located in ciliary basal body	IDA IDA: Inferred from direct assay	17646400	GOA
located in cytoplasmic vesicle	IDA IDA: Inferred from direct assay	17658474	GOA
located in cytosol	IDA IDA: Inferred from direct assay	24529379	GOA
is active in lysosomal membrane	IDA IDA: Inferred from direct assay	24529379	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

TBC1 domain family member 7

TBC1D7-LOC100130357 Protein-protein interaction Information

Type Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TBC1D7	Q9P0N9	TSC1	Homo sapiens	Q92574	Anti Tag CoIP	33436626
Intra	TBC1D7	Q9P0N9	TSC1	Homo sapiens	Q92574	Anti Tag CoIP	33961781
Intra	TBC1D7	Q9P0N9	TSC1	Homo sapiens	Q92574	Anti Tag CoIP	28514442
Intra	TBC1D7	Q9P0N9	TSC1	Homo sapiens	Q92574	3D-EM	33436626
Intra	TBC1D7	Q9P0N9	RPGRIP1	Homo sapiens	Q96KN7	Validated Y2H	25416956
Intra	TBC1D7	Q9P0N9	KRT35	Homo sapiens	Q92764	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	KRT35	Homo sapiens	Q92764	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	MMADHC	Homo sapiens	Q9H3L0	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	MMADHC	Homo sapiens	Q9H3L0	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	LZTS1	Homo sapiens	Q9Y250	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	LZTS1	Homo sapiens	Q9Y250	Validated Y2H	32296183
Intra	TBC1D7	Q9P0N9	LZTS1	Homo sapiens	Q9Y250	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	SSNA1	Homo sapiens	O43805	Y2H Array	25416956
Intra	TBC1D7	Q9P0N9	SSNA1	Homo sapiens	O43805	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	SSNA1	Homo sapiens	O43805	Y2H Prey Pooling	25416956
Intra	TBC1D7	Q9P0N9	SSNA1	Homo sapiens	O43805	Validated Y2H	25416956
Intra	TBC1D7	Q9P0N9	SSNA1	Homo sapiens	O43805	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	BLZF1	Homo sapiens	Q9H2G9	Validated Y2H	25416956
Intra	TBC1D7	Q9P0N9	BLZF1	Homo sapiens	Q9H2G9	Y2H Array	25416956
Intra	TBC1D7	Q9P0N9	BLZF1	Homo sapiens	Q9H2G9	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	BLZF1	Homo sapiens	Q9H2G9	Y2H Prey Pooling	25416956
Intra	TBC1D7	Q9P0N9	BLZF1	Homo sapiens	Q9H2G9	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	MIPOL1	Homo sapiens	Q8TD10	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	MIPOL1	Homo sapiens	Q8TD10	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	BAG4	Homo sapiens	O95429	BFG-2H	27107012
Intra	TBC1D7	Q9P0N9	BAG4	Homo sapiens	O95429	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	BAG4	Homo sapiens	O95429	Validated Y2H	27107012
Intra	TBC1D7	Q9P0N9	BAG4	Homo sapiens	O95429	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	XPA	Homo sapiens	P23025	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	XPA	Homo sapiens	P23025	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	TRAF4	Homo sapiens	Q9BUZ4	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	TRAF4	Homo sapiens	Q9BUZ4	Validated Y2H	27107012
Intra	TBC1D7	Q9P0N9	TRAF4	Homo sapiens	Q9BUZ4	BFG-2H	27107012
Intra	TBC1D7	Q9P0N9	TRAF4	Homo sapiens	Q9BUZ4	Y2H Array	25416956
Intra	TBC1D7	Q9P0N9	TRAF4	Homo sapiens	Q9BUZ4	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	INCA1	Homo sapiens	Q0VD86	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	INCA1	Homo sapiens	Q0VD86	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	TRIM62	Homo sapiens	Q9BVG3	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	TRIM62	Homo sapiens	Q9BVG3	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	LDOC1	Homo sapiens	O95751	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	LDOC1	Homo sapiens	O95751	Y2H Array	25416956
Intra	TBC1D7	Q9P0N9	LDOC1	Homo sapiens	O95751	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25416956
Intra	TBC1D7	Q9P0N9	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	25416956
Intra	TBC1D7	Q9P0N9	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	KRT19	Homo sapiens	P08727	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	HOOK1	Homo sapiens	Q9UJC3	Validated Y2H	32296183
Intra	TBC1D7	Q9P0N9	HOOK1	Homo sapiens	Q9UJC3	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	HOOK1	Homo sapiens	Q9UJC3	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	HOOK1	Homo sapiens	Q9UJC3	Y2H Prey Pooling	25416956
Intra	TBC1D7	Q9P0N9	SH3GLB2	Homo sapiens	Q9NR46	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	SH3GLB2	Homo sapiens	Q9NR46	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	KEAP1	Homo sapiens	Q14145	Y2H Array	32296183
Intra	TBC1D7	Q9P0N9	KEAP1	Homo sapiens	Q14145	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	TBC1D7	Q9P0N9	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

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