2. Gene
  3. TBC1D7-LOC100130357 - TBC1D7-LOC100130357 readthrough Gene

TBC1D7-LOC100130357 - TBC1D7-LOC100130357 readthrough Gene

  • Gene
  • Protein
Homo sapiens (human)
Gene ID: 107080638 | Gene type: protein coding

About TBC1D7-LOC100130357

Summary

This locus represents naturally occurring readthrough transcription between the neighboring TBC1D7 (TBC1 domain family member 7) gene and downstream uncharacterized LOC100130357 on chromosome 6. Readthrough transcripts may encode the same protein as TBC1 domain family member 7 or may be candidates for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Jan 2016]

TBC1D7-LOC100130357 Products(1)

mRNA Protein Name
NR_134872.2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
17646400 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
17658474 GOA
enables small GTPase binding IPI
IPI: Inferred from physical interaction
17646400 GOA
Biological Process GO Annotation Evidence Reference Source
involved in activation of GTPase activity IMP
IMP: Inferred from mutant phenotype
22795129 GOA
involved in cellular response to starvation IDA
IDA: Inferred from direct assay
24529379 GOA
involved in negative regulation of TOR signaling IDA
IDA: Inferred from direct assay
22795129 GOA
involved in negative regulation of TOR signaling IMP
IMP: Inferred from mutant phenotype
22795129 GOA
involved in negative regulation of TORC1 signaling IDA
IDA: Inferred from direct assay
24529379 GOA
involved in negative regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
17646400 GOA
involved in positive regulation of GTPase activity IDA
IDA: Inferred from direct assay
17646400 GOA
involved in positive regulation of protein ubiquitination IDA
IDA: Inferred from direct assay
17658474 GOA
involved in response to growth factor IMP
IMP: Inferred from mutant phenotype
22795129 GOA
Cellular Component GO Annotation Evidence Reference Source
part of TSC1-TSC2 complex IDA
IDA: Inferred from direct assay
24529379 GOA
part of TSC1-TSC2 complex IPI
IPI: Inferred from physical interaction
22795129 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
17646400 GOA
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
17658474 GOA
located in cytosol IDA
IDA: Inferred from direct assay
24529379 GOA
is active in lysosomal membrane IDA
IDA: Inferred from direct assay
24529379 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TBC1 domain family member 7

TBC1D7-LOC100130357 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra TBC1D7 Q9P0N9 TSC1 Homo sapiens Q92574
Anti Tag CoIP
33436626
Intra TBC1D7 Q9P0N9 TSC1 Homo sapiens Q92574
Anti Tag CoIP
33961781
Intra TBC1D7 Q9P0N9 TSC1 Homo sapiens Q92574
Anti Tag CoIP
28514442
Intra TBC1D7 Q9P0N9 TSC1 Homo sapiens Q92574
3D-EM
33436626
Intra TBC1D7 Q9P0N9 RPGRIP1 Homo sapiens Q96KN7
Validated Y2H
25416956
Intra TBC1D7 Q9P0N9 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 MMADHC Homo sapiens Q9H3L0
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 MMADHC Homo sapiens Q9H3L0
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra TBC1D7 Q9P0N9 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 SSNA1 Homo sapiens O43805
Y2H Array
25416956
Intra TBC1D7 Q9P0N9 SSNA1 Homo sapiens O43805
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
25416956
Intra TBC1D7 Q9P0N9 SSNA1 Homo sapiens O43805
Validated Y2H
25416956
Intra TBC1D7 Q9P0N9 SSNA1 Homo sapiens O43805
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
25416956
Intra TBC1D7 Q9P0N9 BLZF1 Homo sapiens Q9H2G9
Y2H Array
25416956
Intra TBC1D7 Q9P0N9 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
25416956
Intra TBC1D7 Q9P0N9 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 BAG4 Homo sapiens O95429
BFG-2H
27107012
Intra TBC1D7 Q9P0N9 BAG4 Homo sapiens O95429
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 BAG4 Homo sapiens O95429
Validated Y2H
27107012
Intra TBC1D7 Q9P0N9 BAG4 Homo sapiens O95429
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 XPA Homo sapiens P23025
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 XPA Homo sapiens P23025
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
27107012
Intra TBC1D7 Q9P0N9 TRAF4 Homo sapiens Q9BUZ4
BFG-2H
27107012
Intra TBC1D7 Q9P0N9 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
25416956
Intra TBC1D7 Q9P0N9 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 TRIM62 Homo sapiens Q9BVG3
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 TRIM62 Homo sapiens Q9BVG3
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 LDOC1 Homo sapiens O95751
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 LDOC1 Homo sapiens O95751
Y2H Array
25416956
Intra TBC1D7 Q9P0N9 LDOC1 Homo sapiens O95751
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 LZTS2 Homo sapiens Q9BRK4
Y2H Array
25416956
Intra TBC1D7 Q9P0N9 KRT19 Homo sapiens P08727
Y2H Prey Pooling
25416956
Intra TBC1D7 Q9P0N9 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 HOOK1 Homo sapiens Q9UJC3
Validated Y2H
32296183
Intra TBC1D7 Q9P0N9 HOOK1 Homo sapiens Q9UJC3
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 HOOK1 Homo sapiens Q9UJC3
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 HOOK1 Homo sapiens Q9UJC3
Y2H Prey Pooling
25416956
Intra TBC1D7 Q9P0N9 SH3GLB2 Homo sapiens Q9NR46
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 SH3GLB2 Homo sapiens Q9NR46
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 KEAP1 Homo sapiens Q14145
Y2H Array
32296183
Intra TBC1D7 Q9P0N9 KEAP1 Homo sapiens Q14145
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra TBC1D7 Q9P0N9 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction