TRAF4 - TNF receptor associated factor 4 Gene

Homo sapiens

Also known as CART1; MLN62; RNF83

Gene ID: 9618 | Gene type: protein coding

About TRAF4

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,744,011-28,750,956 (from NCBI)

This gene has 16 transcripts (splice variants), 213 orthologues and 5 paralogues. Ubiquitous expression in duodenum (RPKM 13.1), small intestine (RPKM 10.0) and 24 other tissues.

Summary

This gene encodes a member of the TNF Receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF Receptor Superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

TRAF4 Products(1)

mRNA	Protein	Name
NM_004295.4	NP_004286.2	TNF receptor-associated factor 4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables WW domain binding	IPI IPI: Inferred from physical interaction	19937093	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	24311986	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10514511	GOA
enables thioesterase binding	IPI IPI: Inferred from physical interaction	11279055	GOA
enables tumor necrosis factor receptor binding	IPI IPI: Inferred from physical interaction	11728344	GOA
enables ubiquitin protein ligase binding	IPI IPI: Inferred from physical interaction	11279055	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of JNK cascade	IDA IDA: Inferred from direct assay	16157600	GOA
involved in positive regulation of protein kinase activity	IDA IDA: Inferred from direct assay	16157600	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16157600	GOA
located in nucleus	IDA IDA: Inferred from direct assay	18087216	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAF4 Protein Structure

zf-C3HC4

zf-TRAF

MATH

0
100
200
300
400
470 a.a.

Protein Preferred Names

Protein Names

TNF receptor-associated factor 4

MLN 62

TRAF4 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TRAF4	Q9BUZ4	KRT40	Homo sapiens	Q6A162	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	HOMEZ	Homo sapiens	Q8IX15-3	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	HOMEZ	Homo sapiens	Q8IX15-3	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	BCL6B	Homo sapiens	A8KA13	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	TP53BP2	Homo sapiens	Q13625-3	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	TP53BP2	Homo sapiens	Q13625-3	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	NPIPA7	Homo sapiens	E9PJI5	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZNF3	Homo sapiens	Q86U76	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	REXO1L1P	Homo sapiens	Q8IX06	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	REXO1L1P	Homo sapiens	Q8IX06	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	UBL4B	Homo sapiens	Q8N7F7	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	UBL4B	Homo sapiens	Q8N7F7	Y2H Array	31515488
Intra	TRAF4	Q9BUZ4	UBL4B	Homo sapiens	Q8N7F7	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	UBL4B	Homo sapiens	Q8N7F7	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	EXOC7	Homo sapiens	Q96BU6	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	EXOC7	Homo sapiens	Q96BU6	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	EXOC7	Homo sapiens	Q96BU6	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	TRAF4	Q9BUZ4	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	TRAF4	Q9BUZ4	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	TRAF4	Q9BUZ4	GOLGA6A	Homo sapiens	Q9NYA3	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	GOLGA6A	Homo sapiens	Q9NYA3	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	GOLGA6A	Homo sapiens	Q9NYA3	Validated Y2H	32296183
Cross	TRAF4	Q9BUZ4	q9e7p0_9flav	Dengue virus 2	Q9E7P0	Y2H Array	22014111
Intra	TRAF4	Q9BUZ4	NHERF2	Homo sapiens	Q15599	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	BANP	Homo sapiens	Q8N9N5-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	BANP	Homo sapiens	Q8N9N5-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	PCSK5	Homo sapiens	Q92824-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	PCSK5	Homo sapiens	Q92824-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	KRT36	Homo sapiens	O76013-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	KRT36	Homo sapiens	O76013-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ACTMAP	Homo sapiens	Q5BKX5-3	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DISC1	Homo sapiens	Q9NRI5-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DISC1	Homo sapiens	Q9NRI5-2	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	DISC1	Homo sapiens	Q9NRI5-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	PLEKHA7	Homo sapiens	Q6IQ23-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	PLEKHA7	Homo sapiens	Q6IQ23-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZNF177	Homo sapiens	Q13360-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZNF177	Homo sapiens	Q13360-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	CEP85	Homo sapiens	Q6P2H3-3	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	CEP85	Homo sapiens	Q6P2H3-3	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	EYA2	Homo sapiens	O00167-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	EYA2	Homo sapiens	O00167-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	POLR2J3	Homo sapiens	Q9H1A7	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	POLR2J3	Homo sapiens	Q9H1A7	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	POLR2J3	Homo sapiens	Q9H1A7	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	EZHIP	Homo sapiens	Q86X51	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	EZHIP	Homo sapiens	Q86X51	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	TYK2	Homo sapiens	P29597	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	TYK2	Homo sapiens	P29597	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	ZNF3	Homo sapiens	P17036	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	BACH2	Homo sapiens	Q9BYV9	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	BACH2	Homo sapiens	Q9BYV9	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	BACH2	Homo sapiens	Q9BYV9	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZNF275	Homo sapiens	Q9NSD4	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZNF275	Homo sapiens	Q9NSD4	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZNF275	Homo sapiens	Q9NSD4	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZMYM5	Homo sapiens	Q9UJ78-2	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DPEP2NB	Homo sapiens	A0A0U1RQF7	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DPEP2NB	Homo sapiens	A0A0U1RQF7	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	DTX3	Homo sapiens	Q8N9I9	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DTX3	Homo sapiens	Q8N9I9	Y2H Array	22493164
Intra	TRAF4	Q9BUZ4	DTX3	Homo sapiens	Q8N9I9	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	GORASP1	Homo sapiens	Q9BQQ3	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	GORASP1	Homo sapiens	Q9BQQ3	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	TOR1A	Homo sapiens	O14656-2	Y2H Pooling	32814053
Intra	TRAF4	Q9BUZ4	TOR1A	Homo sapiens	O14656-2	Validated Y2H	32814053
Intra	TRAF4	Q9BUZ4	TOR1A	Homo sapiens	O14656-2	Y2H Array	32814053
Intra	TRAF4	Q9BUZ4	VPS52	Homo sapiens	Q8N1B4	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	TPP1	Homo sapiens	O14773	Validated Y2H	32814053
Intra	TRAF4	Q9BUZ4	TPP1	Homo sapiens	O14773	Y2H Array	32814053
Intra	TRAF4	Q9BUZ4	TPP1	Homo sapiens	O14773	Y2H Pooling	32814053
Intra	TRAF4	Q9BUZ4	ZC3H12C	Homo sapiens	Q9C0D7	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZC3H12C	Homo sapiens	Q9C0D7	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZC3H12C	Homo sapiens	Q9C0D7	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	PLAGL2	Homo sapiens	Q9UPG8	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	PLAGL2	Homo sapiens	Q9UPG8	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	PLAGL2	Homo sapiens	Q9UPG8	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	TBC1D7	Homo sapiens	Q9P0N9	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	TBC1D7	Homo sapiens	Q9P0N9	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	TBC1D7	Homo sapiens	Q9P0N9	Y2H Array	31515488
Intra	TRAF4	Q9BUZ4	TBC1D7	Homo sapiens	Q9P0N9	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	DNM2	Homo sapiens	P50570	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	DNM2	Homo sapiens	P50570	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	QARS1	Homo sapiens	P47897	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	QARS1	Homo sapiens	P47897	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	SF3B4	Homo sapiens	Q15427	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	SF3B4	Homo sapiens	Q15427	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	UBL4A	Homo sapiens	P11441	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	UBL4A	Homo sapiens	P11441	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	UBL4A	Homo sapiens	P11441	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	UBL4A	Homo sapiens	P11441	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	UBL4A	Homo sapiens	P11441	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	BYSL	Homo sapiens	Q13895	Y2H	21516116
Intra	TRAF4	Q9BUZ4	BYSL	Homo sapiens	Q13895	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	BYSL	Homo sapiens	Q13895	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	BYSL	Homo sapiens	Q13895	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	PSMC3	Homo sapiens	P17980	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	PSMC3	Homo sapiens	P17980	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZBTB26	Homo sapiens	Q9HCK0	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZBTB26	Homo sapiens	Q9HCK0	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZBTB26	Homo sapiens	Q9HCK0	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	POLR2J	Homo sapiens	P52435	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	POLR2J	Homo sapiens	P52435	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	NCF1	Homo sapiens	P14598	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	NCF1	Homo sapiens	P14598	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZNF620	Homo sapiens	Q6ZNG0	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ZNF620	Homo sapiens	Q6ZNG0	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZRANB1	Homo sapiens	Q9UGI0	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZRANB1	Homo sapiens	Q9UGI0	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZRANB1	Homo sapiens	Q9UGI0	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	TAX1BP1	Homo sapiens	Q86VP1	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	TAX1BP1	Homo sapiens	Q86VP1	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ZNF835	Homo sapiens	Q9Y2P0	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	UBA1	Homo sapiens	P22314	Validated Y2H	32814053
Intra	TRAF4	Q9BUZ4	UBA1	Homo sapiens	P22314	Y2H Array	32814053
Intra	TRAF4	Q9BUZ4	UBA1	Homo sapiens	P22314	Y2H Pooling	32814053
Intra	TRAF4	Q9BUZ4	KDM1A	Homo sapiens	O60341	Y2H	23455924
Intra	TRAF4	Q9BUZ4	SPDL1	Homo sapiens	Q96EA4	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	SPDL1	Homo sapiens	Q96EA4	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ISYNA1	Homo sapiens	Q9NPH2	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	ISYNA1	Homo sapiens	Q9NPH2	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	MRPL28	Homo sapiens	Q13084	Y2H Array	31515488
Intra	TRAF4	Q9BUZ4	MRPL28	Homo sapiens	Q13084	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	29892012
Intra	TRAF4	Q9BUZ4	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	KANSL1	Homo sapiens	Q7Z3B3	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	HMG20A	Homo sapiens	Q9NP66	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	HMG20A	Homo sapiens	Q9NP66	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	ABI3	Homo sapiens	Q9P2A4	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ABI3	Homo sapiens	Q9P2A4	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	ABI3	Homo sapiens	Q9P2A4	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	WWP1	Homo sapiens	Q9H0M0	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	BEGAIN	Homo sapiens	Q9BUH8	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	BEGAIN	Homo sapiens	Q9BUH8	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	BAHD1	Homo sapiens	Q8TBE0	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	WWP2	Homo sapiens	O00308	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	WWP2	Homo sapiens	O00308	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	WWP2	Homo sapiens	O00308	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	FBXL18	Homo sapiens	Q96D16	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	FBXL18	Homo sapiens	Q96D16	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	FBXL18	Homo sapiens	Q96D16	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	BANP	Homo sapiens	Q8N9N5	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	ZNF581	Homo sapiens	Q9P0T4	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	ZNF581	Homo sapiens	Q9P0T4	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	ZNF581	Homo sapiens	Q9P0T4	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	CARF	Homo sapiens	Q8N187	Y2H Array	32814053
Intra	TRAF4	Q9BUZ4	CARF	Homo sapiens	Q8N187	Y2H Pooling	32814053
Intra	TRAF4	Q9BUZ4	CARF	Homo sapiens	Q8N187	Validated Y2H	32814053
Intra	TRAF4	Q9BUZ4	ATOSB	Homo sapiens	Q7L5A3	Y2H Array	29892012
Intra	TRAF4	Q9BUZ4	ATOSB	Homo sapiens	Q7L5A3	Y2H	21516116
Intra	TRAF4	Q9BUZ4	HEY2	Homo sapiens	Q9UBP5	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	NOS1AP	Homo sapiens	O75052	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	NOS1AP	Homo sapiens	O75052	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	SUMO1	Homo sapiens	P63165	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	SUMO1	Homo sapiens	P63165	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	ALKBH4	Homo sapiens	Q9NXW9	Y2H Array	31515488
Intra	TRAF4	Q9BUZ4	ALKBH4	Homo sapiens	Q9NXW9	Y2H Prey Pooling	25416956
Intra	TRAF4	Q9BUZ4	ALKBH4	Homo sapiens	Q9NXW9	Validated Y2H	25416956
Intra	TRAF4	Q9BUZ4	ALKBH4	Homo sapiens	Q9NXW9	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	KRT31	Homo sapiens	Q15323	Y2H Array	25416956
Intra	TRAF4	Q9BUZ4	RAD54L2	Homo sapiens	Q9Y4B4	Validated Y2H	32296183
Intra	TRAF4	Q9BUZ4	RAD54L2	Homo sapiens	Q9Y4B4	Y2H Array	32296183
Intra	TRAF4	Q9BUZ4	RAD54L2	Homo sapiens	Q9Y4B4	Y2H Prey Pooling	32296183
Intra	TRAF4	Q9BUZ4	SMURF1	Homo sapiens	Q9HCE7-2	Y2H	19937093
Intra	TRAF4	Q9BUZ4	SMURF1	Homo sapiens	Q9HCE7-2	Pull Down	19937093
Cross	TRAF4	Q9BUZ4	Ngfr	Rattus norvegicus	P07174	Pull Down	10514511
Cross	TRAF4	Q9BUZ4	Ngfr	Rattus norvegicus	P07174	Anti Tag CoIP	10514511

Cross: Cross-species interaction Intra: Intraspecies interaction

TRAF4 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83063	TRAF4 Antibody (YA2808)	WB, ICC/IF, FC	Human, Mouse

Related Diseases

Diseases

Alias

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Intraneural Perineurioma

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14973	TRAF4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TRAF4	VGNC	VGNC:66500
Mus musculus	TRAF4	MGD	MGI:1202880
Canis familiaris	TRAF4	VGNC	VGNC:47768
Macaca mulatta	TRAF4	VGNC	VGNC:78643
Bos taurus	TRAF4	VGNC	VGNC:36276
Rattus norvegicus	TRAF4	RGD	RGD:1306708

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