2. Gene
  3. Ido1 - indoleamine 2,3-dioxygenase 1 Gene

Ido1 - indoleamine 2,3-dioxygenase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ido; Indo

Gene ID: 15930 | Gene type: protein coding

About Ido1

Chromosome 8: 25,074,152-25,087,025 reverse strand.GRCm39:CM001001.3

This gene has 2 transcripts (splice variants), 98 orthologues and is associated with 34 phenotypes. Biased expression in genital fat pad adult (RPKM 37.1), mammary gland adult (RPKM 7.7) and 2 other tissues.

Summary

Enables tryptophan 2,3-dioxygenase activity. Acts upstream of or within several processes, including carboxylic acid metabolic process; regulation of apoptotic process; and regulation of cytokine production. Located in smooth muscle contractile fiber and stereocilium bundle. Is expressed in cerebral cortex; corpus striatum; embryo; extraembryonic component; and hippocampus. Used to study pre-eclampsia. Orthologous to human IDO1 (indoleamine 2,3-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ido1 Products(2)

mRNA Protein Name
NM_008324.3 NP_032350.1 indoleamine 2,3-dioxygenase 1 isoform 1
NM_001293690.2 NP_001280619.1 indoleamine 2,3-dioxygenase 1 isoform 2

Ido1 Protein Structure

IDO

IDO: pfam01231 (15 - 401)

  • 0
  • 100
  • 200
  • 300
  • 407 a.a.
Protein Preferred Names Protein Names

indoleamine 2,3-dioxygenase 1

IDO-1

indole 2,3-dioxygenase

indoleamine-pyrrole 2,3 dioxygenase

Recombinant Ido1 Proteins

Cat. No. Product Name Accession Purity
HY-P72616 IDO Protein, Mouse (His) P28776 (M1-P407) ≥95%

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0110 Palmatine chloride Inhibitor 99.81% Unkown
HY-N0110A Palmatine Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-15689 Epacadostat Inhibitor 99.66% Phase 3
HY-101560 Linrodostat Inhibitor 99.81% Phase 3
HY-101111 PF-06840003 Inhibitor 99.87% Phase 1
Pre-clinical Phase
Bioactive Molecules (30)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13983 IDO-IN-7 Inhibitor 99.98% Unkown
HY-148383 DP00477 Inhibitor 99.03% Unkown
HY-N0110B Palmatine hydroxide Inhibitor 99.64% Unkown
HY-111540 LY-3381916 Inhibitor 99.54% Unkown
HY-151108 IDO1/TDO-IN-4 Inhibitor 99.23% Unkown
HY-151093 IDO2-IN-1 Inhibitor 98.86% Unkown
HY-131911 PROTAC IDO1 Degrader-1 Inhibitor 98.17% Unkown
HY-18769 BMS-978587 Inhibitor 99.92% Unkown
HY-139204 BMS-986242 Inhibitor 99.42% Unkown
HY-112147 IDO1 and HDAC1 Inhibitor Inhibitor / Unkown
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% Unkown
HY-120742 MMG-0358 Inhibitor / Unkown
HY-144652 IDO1-IN-19 Inhibitor 98.52% Unkown
HY-147772 ZC0101 Inhibitor / Unkown
HY-144274 IDO1-IN-14 Inhibitor / Unkown
HY-144468 IDO1-IN-17 Inhibitor / Unkown
HY-161348 AT-0174 Inhibitor / Unkown
HY-144465 IDO1-IN-15 Inhibitor / Unkown
HY-151886 NU223612 Inhibitor / Unkown
HY-144778 IDO1/TDO-IN-1 Inhibitor / Unkown
HY-144466 IDO1-IN-16 Inhibitor / Unkown
HY-158334 NDs-IN-1 Inhibitor / Unkown
HY-144273 IDO1-IN-13 Inhibitor / Unkown
HY-130607 IDO1-IN-2 Inhibitor / Unkown
HY-149227 IDO1-IN-21 Inhibitor / Unkown
HY-148572 NAMPT/IDO1-IN-1 Inhibitor / Unkown
HY-D0033 Roxyl-9 Inhibitor 99.22% Unkown
HY-154387 1-Isopropyltryptophan Inhibitor / Unkown
HY-101560A Linrodostat mesylate Inhibitor / Unkown
HY-78699 2-Hydrazinobenzothiazole Inhibitor 99.95% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ido1 NCBI NCBI:3620