2. Gene
  3. TSPO2 - translocator protein 2 Gene

TSPO2 - translocator protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BZRPL1

Gene ID: 222642 | Gene type: protein coding

About TSPO2

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,041,386-41,044,337 (from NCBI)

This gene has 3 transcripts (splice variants), 165 orthologues and 1 paralogue. Biased expression in bone marrow (RPKM 6.9) and testis (RPKM 0.2).

Summary

Predicted to enable Cholesterol binding activity. Involved in amino acid import across plasma membrane. Located in organelle membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TSPO2 Products(2)

mRNA Protein Name
NM_001010873.3 NP_001010873.1 translocator protein 2
NM_001159726.1 NP_001153198.1 translocator protein 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 5-aminolevulinic acid transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
31989647 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in 5-aminolevulinic acid import across plasma membrane IMP
IMP: Inferred from mutant phenotype
31989647 GOA
involved in import across plasma membrane IDA
IDA: Inferred from direct assay
27641616 GOA
Cellular Component GO Annotation Evidence Reference Source
located in organelle membrane IDA
IDA: Inferred from direct assay
27641616 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
27641616 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPO2 Protein Structure

TspO_MBR

TspO_MBR: TspO/MBR family (7 - 154)

  • 0
  • 100
  • 170 a.a.
Protein Preferred Names Protein Names

translocator protein 2

benzodiazapine receptor (peripheral)-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15178 TSPO2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TSPO2 RGD RGD:1594018
Bos taurus TSPO2 VGNC VGNC:55923
Felis catus TSPO2 VGNC VGNC:102542
Canis familiaris TSPO2 VGNC VGNC:49105
Mus musculus TSPO2 MGD MGI:1917276
Macaca mulatta TSPO2 VGNC VGNC:83960