2. Gene
  3. Igf1 - insulin-like growth factor 1 Gene

Igf1 - insulin-like growth factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IGF

Gene ID: 24482 | Gene type: protein coding

About Igf1

Summary

Enables protein serine/threonine kinase activator activity; signaling receptor binding activity; and steroid binding activity. Involved in several processes, including cellular response to hormone stimulus; negative regulation of cell death; and positive regulation of cell differentiation. Located in several cellular components, including interstitial matrix; neuronal cell body; and platelet alpha granule. Used to study brain ischemia; diabetic neuropathy; and hypertension. Biomarker of several diseases, including alcoholic neuropathy; artery disease (multiple); congenital diaphragmatic hernia; folic acid deficiency anemia; and hypothyroidism (multiple). Human ortholog(s) of this gene implicated in several diseases, including acne; brain ischemia; diabetes mellitus (multiple); myopia; and neurodegenerative disease (multiple). Orthologous to human IGF1 (Insulin like growth factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Igf1 Products(4)

mRNA Protein Name
NM_001082477.2 NP_001075946.2 insulin-like growth factor I isoform a preproprotein
NM_001082478.1 NP_001075947.1 insulin-like growth factor I isoform c preproprotein
NM_001082479.1 NP_001075948.1 insulin-like growth factor I isoform d preproprotein
NM_178866.4 NP_849197.3 insulin-like growth factor I isoform b preproprotein
Protein Preferred Names Protein Names

insulin-like growth factor I

IGF-I

somatomedin

Recombinant Igf1 Proteins

Cat. No. Product Name Accession Purity
HY-P7203 IGF-I/IGF-1 Protein, Rat P08025 (G49-A118) ≥95%

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15656 Ceritinib Inhibitor 99.98% Yes
HY-15656A Ceritinib dihydrochloride Inhibitor 99.57% Yes
HY-B0025 Voglibose Inhibitor ≥98.0% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99165 Teprotumumab Inhibitor 99.46% Unkown
Clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-10191 Linsitinib Inhibitor 99.84% Phase 3
HY-109155 Paltusotine Agonist 99.52% Phase 3
HY-15494 Picropodophyllin 99.85% Phase 2
HY-10200 BMS-754807 Inhibitor 99.41% Phase 2
HY-153485 Cimdelirsen Inhibitor / Phase 2
HY-153485A Cimdelirsen sodium Inhibitor / Phase 2
HY-15749 XL228 Inhibitor 99.64% Phase 1
HY-B0794B AZ7550 Mesylate Inhibitor 99.24% Phase 1
HY-13326 ASP3026 99.88% Phase 1
HY-B0794A AZ7550 hydrochloride Inhibitor 98.66% Phase 1
HY-135749 BN201 / Phase 1
Inhibitory Antibodies (8)
Cat. No. Product Name Effect
Purity Phase
HY-P99294 Ganitumab Inhibitor 96.00% Phase 3
HY-P99197 Figitumumab Inhibitor 96.89% Phase 3
HY-P99274 Xentuzumab Antagonist 95.00% Phase 2
HY-P99284 Dalotuzumab 97.43% Phase 2
HY-P99712 Lonigutamab Inhibitor 95.00% Phase 2
HY-P99218 Robatumumab Inhibitor / Phase 2
HY-P99867 Dusigitumab / Phase 2
HY-P99672 Istiratumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (38)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108477 TMPyP4 tosylate Inhibitor ≥98.0% Unkown
HY-116624 MAZ51 99.96% Unkown
HY-50866 NVP-AEW541 99.92% Unkown
HY-10262 BMS-536924 99.83% Unkown
HY-15609 AZD-3463 99.58% Unkown
HY-10252 NVP-ADW742 99.54% Unkown
HY-10524 GSK1904529A 99.66% Unkown
HY-N0908 Ginsenoside Rg5 99.87% Unkown
HY-13203 NVP-TAE 226 99.77% Unkown
HY-10253 AG1024 99.82% Unkown
HY-18785 Indirubin Derivative E804 Inhibitor 98.54% Unkown
HY-100349 SU4312 Inhibitor 99.76% Unkown
HY-135680 I-OMe-Tyrphostin AG 538 Inhibitor 98.03% Unkown
HY-145110 IGF-1R inhibitor-2 Inhibitor 98.36% Unkown
HY-P2090A Angiopeptin TFA 99.71% Unkown
HY-RS06614 IGF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-135436 AG 538 Inhibitor 99.80% Unkown
HY-B0794 AZ7550 Inhibitor / Unkown
HY-139783 3-Campholenyl-2-butanol Inhibitor ≥98.0% Unkown
HY-125102 AZ12253801 Inhibitor / Unkown
HY-50866B NVP-AEW541 dihydrochloride / Unkown
HY-108230 ALK-IN-12 Inhibitor / Unkown
HY-15494S1 Picropodophyllin-d6 / Unkown
HY-156914 IGF-1R/SRC-IN-1 Inhibitor 99.86% Unkown
HY-162506 IGF-1R inhibitor-3 Inhibitor / Unkown
HY-402309 IGF-1R modulator 1 Modulator / Unkown
HY-B0794S AZ7550-d5 Inhibitor / Unkown
HY-P2090 Angiopeptin / Unkown
HY-RS06615 IGF1R Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06616 Igf1r Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06617 Igf1r Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-100349A cis-SU4312 Inhibitor / Unkown
HY-117885 PF-5177624 Inhibitor / Unkown
HY-119112A LY 379196 Inhibitor / Unkown
HY-138257A (R)-Indeloxazine benzenesulfonate Inhibitor / Unkown
HY-14357 BMS 695735 Inhibitor / Unkown
HY-21291 SU-4313 Modulator / Unkown
HY-N6611 Chimaphilin Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990084 Veligrotug Inhibitor 99.25% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igf1 NCBI NCBI:3479
Macaca fascicularis Igf1 NCBI NCBI:102128018
Mus musculus Igf1 NCBI NCBI:16000