2. Gene
  3. CCDC88B - coiled-coil domain containing 88B Gene

CCDC88B - coiled-coil domain containing 88B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BRLZ; HKRP3; gipie; CCDC88

Gene ID: 283234 | Gene type: protein coding

About CCDC88B

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,340,204-64,357,534 (from NCBI)

This gene has 10 transcripts (splice variants), 181 orthologues and 5 paralogues. Biased expression in bone marrow (RPKM 19.8), spleen (RPKM 16.5) and 13 other tissues.

Summary

This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]

CCDC88B Products(1)

mRNA Protein Name
NM_032251.6 NP_115627.6 coiled-coil domain-containing protein 88B precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC88B Protein Structure

HOOK

HOOK: HOOK protein (56 - 423)

  • 0
  • 300
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  • 1200
  • 1476 a.a.
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 88B

78 kDa glucose-regulated protein [GRP78]-interacting protein induced by ER stress

Related Diseases

Diseases Alias
Leprosy 3

Leprosy

Leprosy, Susceptibility To, 3

Hansen'S Disease

Leprosy, Susceptibility To

Hansen Disease

Infection Due To Mycobacterium Leprae

LPRS3

Leprosy, Type 3

Anaesthesia Leprosy

Anaesthetic Leprosy

Maculoanaesthetic Leprosy

Macular Leprosy

Leprosy Unspecified
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02062 CCDC88B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CCDC88B VGNC VGNC:38868
Rattus norvegicus CCDC88B RGD RGD:1311475
Macaca mulatta CCDC88B VGNC VGNC:100902
Felis catus CCDC88B VGNC VGNC:60523
Bos taurus CCDC88B VGNC VGNC:26928
Mus musculus CCDC88B MGD MGI:1925567