2. Gene
  3. TSG101 - tumor susceptibility 101 Gene

TSG101 - tumor susceptibility 101 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TSG10; VPS23

Gene ID: 7251 | Gene type: protein coding

About TSG101

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:18,480,311-18,526,942 (from NCBI)

This gene has 12 transcripts (splice variants), 227 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 34.7), adrenal (RPKM 31.6) and 25 other tissues.

Summary

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating Enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast Cancer and suggest that defects occur during breast Cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

TSG101 Products(1)

mRNA Protein Name
NM_006292.4 NP_006283.1 tumor susceptibility gene 101 protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium-dependent protein binding IPI
IPI: Inferred from physical interaction
19520058 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12802020 GOA
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
14519844 GOA
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
16973552 GOA
enables ubiquitin binding IDA
IDA: Inferred from direct assay
11595185 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
17229889 GOA
enables virion binding IDA
IDA: Inferred from direct assay
11595185 GOA
Biological Process GO Annotation Evidence Reference Source
involved in extracellular transport IMP
IMP: Inferred from mutant phenotype
22315426 GOA
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16554368 GOA
involved in negative regulation of epidermal growth factor-activated receptor activity IMP
IMP: Inferred from mutant phenotype
16973552 GOA
involved in positive regulation of exosomal secretion IMP
IMP: Inferred from mutant phenotype
22660413 GOA
involved in positive regulation of viral budding via host ESCRT complex IMP
IMP: Inferred from mutant phenotype
11595185 GOA
involved in regulation of MAP kinase activity IMP
IMP: Inferred from mutant phenotype
17714434 GOA
involved in regulation of extracellular exosome assembly IMP
IMP: Inferred from mutant phenotype
24105262 GOA
involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IDA
IDA: Inferred from direct assay
15611048 GOA
involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IMP
IMP: Inferred from mutant phenotype
21757351 GOA
involved in viral budding IMP
IMP: Inferred from mutant phenotype
15126635 GOA
involved in viral release from host cell IMP
IMP: Inferred from mutant phenotype
11595185 GOA
Cellular Component GO Annotation Evidence Reference Source
part of ESCRT I complex IDA
IDA: Inferred from direct assay
18005716 GOA
part of ESCRT I complex IPI
IPI: Inferred from physical interaction
18005716 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
18077552 GOA
located in early endosome IDA
IDA: Inferred from direct assay
11916981 GOA
located in endosome IDA
IDA: Inferred from direct assay
17940959 GOA
located in extracellular exosome IDA
IDA: Inferred from direct assay
15326289 GOA
located in late endosome IMP
IMP: Inferred from mutant phenotype
15126635 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
17940959 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSG101 Protein Structure

UEV

UEV: UEV domain (22 - 141)

Vps23_core

Vps23_core: Vps23 core domain (315 - 379)

  • 0
  • 100
  • 200
  • 300
  • 390 a.a.
Protein Preferred Names Protein Names

tumor susceptibility gene 101 protein

ESCRT-I complex subunit TSG101

TSG101 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
TSG101 Q99816 ZWINT Homo sapiens O95229
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 ZWINT Homo sapiens O95229
Y2H Array
32296183
Intra
TSG101 Q99816 KRT13 Homo sapiens A1A4E9
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 KRT13 Homo sapiens A1A4E9
Y2H Array
25416956
Intra
TSG101 Q99816 FAM9B Homo sapiens Q8IZU0
Validated Y2H
25416956
Intra
TSG101 Q99816 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 VPS37A Homo sapiens Q8NEZ2-2
Y2H Array
25416956
Intra
TSG101 Q99816 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
TSG101 Q99816 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
TSG101 Q99816 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 GLI2 Homo sapiens P10070
Phage Display
35044719
Intra
TSG101 Q99816 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra
TSG101 Q99816 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
TSG101 Q99816 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
TSG101 Q99816 TRIML2 Homo sapiens Q8N7C3
Y2H Array
32296183
Intra
TSG101 Q99816 TRIML2 Homo sapiens Q8N7C3
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 CEP63 Homo sapiens Q96MT8-3
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 CEP63 Homo sapiens Q96MT8-3
Y2H Array
32296183
Intra
TSG101 Q99816 CAGE1 Homo sapiens Q8TC20-4
Y2H Array
32296183
Intra
TSG101 Q99816 CAGE1 Homo sapiens Q8TC20-4
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 LCN2 Homo sapiens P80188
Y2H Array
32296183
Intra
TSG101 Q99816 LCN2 Homo sapiens P80188
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41-2
Validated Y2H
32296183
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41-2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41-2
Y2H Array
32296183
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41-2
Y2H Array
31515488
Intra
TSG101 Q99816 SCARA5 Homo sapiens Q6ZMJ2-2
Y2H Array
32296183
Intra
TSG101 Q99816 SCARA5 Homo sapiens Q6ZMJ2-2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 FAM110A Homo sapiens Q9BQ89
Validated Y2H
32296183
Intra
TSG101 Q99816 MGRN1 Homo sapiens O60291
Phage Display
37219487
Intra
TSG101 Q99816 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
TSG101 Q99816 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
TSG101 Q99816 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 BRPF3 Homo sapiens Q9ULD4-2
Y2H Array
32296183
Intra
TSG101 Q99816 BRPF3 Homo sapiens Q9ULD4-2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 BRPF3 Homo sapiens Q9ULD4-2
Validated Y2H
32296183
Intra
TSG101 Q99816 HAUS1 Homo sapiens Q96CS2
Validated Y2H
25416956
Intra
TSG101 Q99816 HAUS1 Homo sapiens Q96CS2
Y2H Array
32296183
Intra
TSG101 Q99816 HAUS1 Homo sapiens Q96CS2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37C Homo sapiens A5D8V6
Validated Y2H
25416956
Intra
TSG101 Q99816 VPS37C Homo sapiens A5D8V6
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37C Homo sapiens A5D8V6
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 VPS37C Homo sapiens A5D8V6
Anti Tag CoIP
35271311
Intra
TSG101 Q99816 VPS37C Homo sapiens A5D8V6
Y2H Array
32296183
Intra
TSG101 Q99816 PRRC1 Homo sapiens Q96M27
Phage Display
35044719
Intra
TSG101 Q99816 PKNOX2 Homo sapiens Q96KN3
Y2H Array
32296183
Intra
TSG101 Q99816 PKNOX2 Homo sapiens Q96KN3
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37A Homo sapiens Q8NEZ2
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 VPS37A Homo sapiens Q8NEZ2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37A Homo sapiens Q8NEZ2
Anti Tag CoIP
35271311
Intra
TSG101 Q99816 VPS37A Homo sapiens Q8NEZ2
Y2H Array
32296183
Intra
TSG101 Q99816 BAG4 Homo sapiens O95429
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 BAG4 Homo sapiens O95429
Y2H Array
32296183
Intra
TSG101 Q99816 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra
TSG101 Q99816 SNAPIN Homo sapiens O95295
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 SNAPIN Homo sapiens O95295
Y2H Array
32296183
Intra
TSG101 Q99816 IQGAP1 Homo sapiens P46940
Y2H
17853893
Intra
TSG101 Q99816 KRT18 Homo sapiens P05783
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KRT18 Homo sapiens P05783
Y2H
19549727
Intra
TSG101 Q99816 KRT18 Homo sapiens P05783
Y2H Array
32296183
Intra
TSG101 Q99816 CD2AP Homo sapiens Q9Y5K6
Anti Tag CoIP
17853893
Intra
TSG101 Q99816 PDCD6IP Homo sapiens Q8WUM4
Phage Display
37219487
Intra
TSG101 Q99816 PDCD6IP Homo sapiens Q8WUM4
SPR
17350572
Intra
TSG101 Q99816 KIAA1328 Homo sapiens Q86T90
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KIAA1328 Homo sapiens Q86T90
Y2H Array
32296183
Intra
TSG101 Q99816 CCDC88B Homo sapiens A6NC98
Y2H Array
32296183
Intra
TSG101 Q99816 CCDC88B Homo sapiens A6NC98
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
Intra
TSG101 Q99816 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 PDLIM7 Homo sapiens Q9NR12
Validated Y2H
25416956
Intra
TSG101 Q99816 PDLIM7 Homo sapiens Q9NR12
Validated Y2H
32296183
Intra
TSG101 Q99816 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra
TSG101 Q99816 TNIP1 Homo sapiens Q15025
Y2H Array
32296183
Intra
TSG101 Q99816 TNIP1 Homo sapiens Q15025
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 HSH2D Homo sapiens Q96JZ2
Y2H Array
32296183
Intra
TSG101 Q99816 HSH2D Homo sapiens Q96JZ2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37B Homo sapiens Q9H9H4
Anti Tag CoIP
35271311
Intra
TSG101 Q99816 VPS37B Homo sapiens Q9H9H4
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 VPS37B Homo sapiens Q9H9H4
Validated Y2H
32296183
Intra
TSG101 Q99816 VPS37B Homo sapiens Q9H9H4
Y2H Array
32296183
Intra
TSG101 Q99816 TAX1BP1 Homo sapiens Q86VP1
Validated Y2H
25416956
Intra
TSG101 Q99816 TAX1BP1 Homo sapiens Q86VP1
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 TAX1BP1 Homo sapiens Q86VP1
Y2H Array
25416956
Intra
TSG101 Q99816 TAX1BP1 Homo sapiens Q86VP1
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 TAX1BP1 Homo sapiens Q86VP1
Y2H Array
32296183
Intra
TSG101 Q99816 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
TSG101 Q99816 SYCE1 Homo sapiens Q8N0S2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 SYCE1 Homo sapiens Q8N0S2
Y2H Array
32296183
Intra
TSG101 Q99816 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra
TSG101 Q99816 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 TOM1L1 Homo sapiens O75674
Y2H
15611048
Intra
TSG101 Q99816 TOM1L1 Homo sapiens O75674
Phage Display
37219487
Intra
TSG101 Q99816 LRSAM1 Homo sapiens Q6UWE0
Y2H Pooling
16189514
Intra
TSG101 Q99816 LRSAM1 Homo sapiens Q6UWE0
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 LRSAM1 Homo sapiens Q6UWE0
Validated Y2H
25416956
Intra
TSG101 Q99816 LRSAM1 Homo sapiens Q6UWE0
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 LRSAM1 Homo sapiens Q6UWE0
Y2H Array
32296183
Intra
TSG101 Q99816 MZB1 Homo sapiens Q8WU39
Y2H Array
32296183
Intra
TSG101 Q99816 MZB1 Homo sapiens Q8WU39
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 ITPRID2 Homo sapiens P28290
Phage Display
35044719
Intra
TSG101 Q99816 ITPRID2 Homo sapiens P28290
Phage Display
37219487
Intra
TSG101 Q99816 PTPN23 Homo sapiens Q9H3S7
Anti Tag CoIP
17174262
Intra
TSG101 Q99816 PTPN23 Homo sapiens Q9H3S7
Y2H
17174262
Intra
TSG101 Q99816 LITAF Homo sapiens Q99732
Anti Bait CoIP
16118794
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41
Anti Tag CoIP
35271311
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41
Y2H Pooling
16189514
Intra
TSG101 Q99816 VPS28 Homo sapiens Q9UK41
Validated Y2H
25416956
Intra
TSG101 Q99816 LNX1 Homo sapiens Q8TBB1
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 LNX1 Homo sapiens Q8TBB1
Y2H Array
32296183
Intra
TSG101 Q99816 HGS Homo sapiens O14964
Y2H
12802020
Intra
TSG101 Q99816 HGS Homo sapiens O14964
Y2H Pooling
16189514
Intra
TSG101 Q99816 HGS Homo sapiens O14964
Anti Tag CoIP
35271311
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
SLC
27107012
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Anti Tag CoIP
17853893
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
BFG-2H
27107012
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H
19549727
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H Pooling
16189514
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H
27107012
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Affinity Chrom
17853893
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Validated Y2H
25416956
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
IF
17853893
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H Array
32296183
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H
17853893
Intra
TSG101 Q99816 CEP55 Homo sapiens Q53EZ4
Y2H Array
25416956
Intra
TSG101 Q99816 DAXX Homo sapiens Q9UER7
CoIP
15033475
Intra
TSG101 Q99816 CBY1 Homo sapiens Q9Y3M2
Validated Y2H
32296183
Intra
TSG101 Q99816 CBY1 Homo sapiens Q9Y3M2
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 CBY1 Homo sapiens Q9Y3M2
Y2H Array
32296183
Intra
TSG101 Q99816 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
TSG101 Q99816 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
TSG101 Q99816 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Intra
TSG101 Q99816 AJUBA Homo sapiens Q96IF1
Y2H Array
32296183
Intra
TSG101 Q99816 AJUBA Homo sapiens Q96IF1
Phage Display
37219487
Intra
TSG101 Q99816 AJUBA Homo sapiens Q96IF1
Y2H Prey Pooling
32296183
Cross
TSG101 Q99816 gag Human immunodeficiency virus P18095
FPS
37219487
Cross
TSG101 Q99816 gag Human immunodeficiency virus P18095
FPS
37100772
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hepatitis E
Charcot-Marie-Tooth Disease, Axonal, Type 2p

CMT2P

Charcot-Marie-Tooth Disease Axonal Type 2p

Charcot-Marie-Tooth Disease Type 2p

Charcot-Marie-Tooth Neuropathy, Type 2p

Charcot-Marie-Tooth Disease, Axonal, Type 2g, Formerly

Cmt2g, Formerly

Charcot-Marie-Tooth Neuropathy Type 2p

Charcot-Marie-Toothe Disease, Axonal, Type 2p

Charcot-Marie-Tooth Disease 2p

Charcot-Marie-Tooth Disease, Axonal Type 2g

Charcot-Marie-Tooth Neuropathy Axonal Type 2p

Cmt2g

Charcot-Marie-Tooth Disease, Type 2p

Charcot-Marie-Tooth Disease, Axonal, Type 2g
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
Charcot-Marie-Tooth Disease

Cmt

Hmsn

Hereditary Motor And Sensory Neuropathy

Pma

Cmt - Charcot-Marie-Tooth Disease

Charcot Marie Tooth Disease

Charcot-Marie-Tooth Hereditary Neuropathy

Charcot-Marie-Tooth Syndrome

Peroneal Muscular Atrophy

Hereditary Motor And Sensory Neuropathies
Charcot-Marie-Tooth Disease, Demyelinating, Type 1c

Charcot-Marie-Tooth Disease Type 1c

CMT1C

Hmsn1c

Hmsn Ic

Charcot-Marie-Tooth Disease, Type 1c

Charcot-Marie-Tooth Neuropathy Type 1c

Cmt, Slow Nerve Conduction Type C

Charcot-Marie-Tooth Neuropathy, Type 1c

Neuropathy, Hereditary Motor And Sensory, Type Ic

Cmt Slow Nerve Conduction Type C

Neuropathy Hereditary Motor And Sensory Type 1c

Charcot-Marie-Tooth Disease 1c

Charcot-Marie-Tooth Disease Demyelinating Type 1c

Hereditary Motor And Sensory Neuropathy Ic

Charcot-Marie-Tooth Disease, Type Ic
Immune Deficiency Disease

Immunodeficiency

Primary Immunodeficiency

Primary Immunodeficiency Disease

Immunologic Deficiency Syndromes

Hypoimmunity

Immune Deficiency Disorder

Immunodeficiency Syndrome

Immune Disorder

Primary Immune Deficiency Disorder

Immune System Diseases

Human Immunodeficiency Virus Infection

Hiv - [Human Immunodeficiency Virus Infection]

Hiv Positive Nos

Hiv Disease

Acquired Immune Deficiency Syndrome-Related Complex

Aids-Like Syndrome

Aids-Related Complex Nos

Arc - [Aids-Related Complex]

Immunodeficiency Due To Human Immunodeficiency Virus Infection

Unspecified Human Immunodeficiency Virus Disease

Hiv Disease Nos

Human Immunodeficiency Virus Positive Nos

Hiv Nos

Deficiency Of Complement Initial Pathway

Deficiency Of Complement Terminal Pathway

Cfdd - [Complement Factor D Deficiency]

Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

Nonfamilial Hypogammaglobulinaemia

Common Variable Immune Deficiency

Nonfamilial Agammaglobulinaemia

Common Variable Agammaglobulinaemia

Agammaglobulinaemia Nos

Agammaglobulinaemia Antibody Deficiency Syndrome

Hypogammaglobulinaemia Antibody Deficiency Syndrome

Acquired Agammaglobulinaemia Nos

Hypogammaglobulinaemia Nos

Hyper Igm
Human Immunodeficiency Virus Type 1

Aids

Hiv/Aids

Aids, Delayed/Rapid Progression To

Hiv-1, Susceptibility To

Hiv-1 Viremia, Susceptibility To

Human Immunodeficiency Virus Type 1, Susceptibility To

Hiv-1

Aids, Slow Progression To

Rapid Progression To Aids From Hiv1 Infection

Hiv1 Infection, Resistance To

Hiv1 Infection

Hiv-1 Viremia

Aids, Resistance To

Aids, Rapid Progression To

Hiv/Aids, Susceptibility To

Hiv-1, Resistance To

Hiv1, Resistance To

Hiv1

Hiv-1 Disease, Delayed Progression Of

Hiv-1 Disease, Rapid Progression Of

Hiv Infection, Resistance To

Hiv Type 1, Susceptibility To

Hiv Type 1

Hiv-1 Infection

Human Immunodeficiency Virus I Infection

Acquired Immunodeficiency Syndrome

Hiv-Infection/Aids
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17421 Tenatoprazole Inhibitor 99.75% Unkown
HY-RS15142 TSG101 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TSG101 VGNC VGNC:47898
Macaca mulatta TSG101 VGNC VGNC:78998
Felis catus TSG101 VGNC VGNC:66613
Bos taurus TSG101 VGNC VGNC:36414
Mus musculus TSG101 MGD MGI:106581
Rattus norvegicus TSG101 RGD RGD:3909