2. Gene
  3. GEM - GTP binding protein overexpressed in skeletal muscle Gene

GEM - GTP binding protein overexpressed in skeletal muscle Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as KIR

Gene ID: 2669 | Gene type: protein coding

About GEM

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:94,249,253-94,262,319 (from NCBI)

This gene has 5 transcripts (splice variants), 201 orthologues and 35 paralogues. Broad expression in gall bladder (RPKM 114.4), urinary bladder (RPKM 36.5) and 15 other tissues.

Summary

The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

GEM Products(2)

mRNA Protein Name
NM_005261.4 NP_005252.1 GTP-binding protein GEM
NM_181702.3 NP_859053.1 GTP-binding protein GEM
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GDP binding IDA
IDA: Inferred from direct assay
17052716 GOA
enables GTP binding IDA
IDA: Inferred from direct assay
17107948 GOA
enables GTPase activity IDA
IDA: Inferred from direct assay
17107948 GOA
enables magnesium ion binding IDA
IDA: Inferred from direct assay
17107948 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12093360 GOA
Biological Process GO Annotation Evidence Reference Source
involved in chromosome organization IMP
IMP: Inferred from mutant phenotype
22964304 GOA
involved in metaphase chromosome alignment IMP
IMP: Inferred from mutant phenotype
22964304 GOA
involved in mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22964304 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
7912851 GOA
located in midbody IDA
IDA: Inferred from direct assay
22964304 GOA
located in mitotic spindle IDA
IDA: Inferred from direct assay
22964304 GOA
located in spindle midzone IDA
IDA: Inferred from direct assay
22964304 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GEM Protein Structure

Ras

Ras: Ras family (77 - 239)

  • 0
  • 100
  • 200
  • 296 a.a.
Protein Preferred Names Protein Names

GTP-binding protein GEM

GTP-binding mitogen-induced T-cell protein

GEM Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
GEM P55040 CCDC102B Homo sapiens Q68D86
Y2H Prey Pooling
25416956
Intra
GEM P55040 CCDC102B Homo sapiens Q68D86
Validated Y2H
25416956
Intra
GEM P55040 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
GEM P55040 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
GEM P55040 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
GEM P55040 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
Intra
GEM P55040 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
GEM P55040 KRTAP10-7 Homo sapiens P60409
Validated Y2H
32296183
Intra
GEM P55040 KRTAP10-7 Homo sapiens P60409
Y2H Array
32296183
Intra
GEM P55040 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
GEM P55040 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
GEM P55040 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
32296183
Intra
GEM P55040 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
GEM P55040 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
GEM P55040 MID2 Homo sapiens Q9UJV3-2
Y2H Array
30886144
Intra
GEM P55040 KRT83 Homo sapiens P78385
Y2H Prey Pooling
32296183
Intra
GEM P55040 KRT83 Homo sapiens P78385
Validated Y2H
32296183
Intra
GEM P55040 KRT83 Homo sapiens P78385
Y2H Array
32296183
Intra
GEM P55040 ZNF774 Homo sapiens Q6NX45
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZNF774 Homo sapiens Q6NX45
Validated Y2H
32296183
Intra
GEM P55040 ZNF774 Homo sapiens Q6NX45
Y2H Array
32296183
Intra
GEM P55040 ISCA2 Homo sapiens Q86U28
Validated Y2H
32296183
Intra
GEM P55040 ISCA2 Homo sapiens Q86U28
Y2H Array
32296183
Intra
GEM P55040 ISCA2 Homo sapiens Q86U28
Y2H Prey Pooling
32296183
Intra
GEM P55040 PBX4 Homo sapiens Q9BYU1
Validated Y2H
32296183
Intra
GEM P55040 PBX4 Homo sapiens Q9BYU1
Y2H Prey Pooling
32296183
Intra
GEM P55040 PBX4 Homo sapiens Q9BYU1
Y2H Array
32296183
Intra
GEM P55040 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
GEM P55040 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
GEM P55040 GAS8 Homo sapiens O95995
Y2H Array
32296183
Intra
GEM P55040 GAS8 Homo sapiens O95995
Y2H Prey Pooling
32296183
Intra
GEM P55040 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 HOOK2 Homo sapiens Q96ED9-2
Validated Y2H
32296183
Intra
GEM P55040 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
GEM P55040 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
GEM P55040 GOPC Homo sapiens Q9HD26-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 GOPC Homo sapiens Q9HD26-2
Validated Y2H
32296183
Intra
GEM P55040 GOPC Homo sapiens Q9HD26-2
Y2H Array
32296183
Intra
GEM P55040 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra
GEM P55040 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra
GEM P55040 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra
GEM P55040 GPRASP3 Homo sapiens Q6PI77
Validated Y2H
32296183
Intra
GEM P55040 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra
GEM P55040 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra
GEM P55040 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
GEM P55040 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra
GEM P55040 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
30886144
Intra
GEM P55040 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
GEM P55040 TRIM69 Homo sapiens Q86WT6-2
Validated Y2H
32296183
Intra
GEM P55040 TRIM69 Homo sapiens Q86WT6-2
Y2H Array
32296183
Intra
GEM P55040 TRIM69 Homo sapiens Q86WT6-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 CARD9 Homo sapiens Q9H257-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 CARD9 Homo sapiens Q9H257-2
Y2H Array
32296183
Intra
GEM P55040 CARD9 Homo sapiens Q9H257-2
Validated Y2H
32296183
Intra
GEM P55040 MSS51 Homo sapiens Q4VC12
Y2H Prey Pooling
32296183
Intra
GEM P55040 MSS51 Homo sapiens Q4VC12
Validated Y2H
32296183
Intra
GEM P55040 MSS51 Homo sapiens Q4VC12
Y2H Array
32296183
Intra
GEM P55040 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra
GEM P55040 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
GEM P55040 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 CDR2 Homo sapiens Q01850
Validated Y2H
32296183
Intra
GEM P55040 CDR2 Homo sapiens Q01850
Y2H Array
32296183
Intra
GEM P55040 CDR2 Homo sapiens Q01850
Y2H Prey Pooling
32296183
Intra
GEM P55040 CACNB3 Homo sapiens P54284
MAPPIT
32296183
Intra
GEM P55040 CACNB3 Homo sapiens P54284
Y2H Array
32296183
Intra
GEM P55040 CACNB3 Homo sapiens P54284
Y2H Prey Pooling
32296183
Intra
GEM P55040 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra
GEM P55040 TP53BP2 Homo sapiens Q05BL1
Validated Y2H
32296183
Intra
GEM P55040 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra
GEM P55040 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra
GEM P55040 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 CCDC125 Homo sapiens Q86Z20
Validated Y2H
32296183
Intra
GEM P55040 CCDC125 Homo sapiens Q86Z20
Y2H Prey Pooling
32296183
Intra
GEM P55040 CCDC125 Homo sapiens Q86Z20
Y2H Array
32296183
Intra
GEM P55040 TRIM10 Homo sapiens Q9UDY6-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 TRIM10 Homo sapiens Q9UDY6-2
Validated Y2H
32296183
Intra
GEM P55040 TRIM10 Homo sapiens Q9UDY6-2
Y2H Array
32296183
Intra
GEM P55040 POF1B Homo sapiens Q8WVV4-1
Y2H Prey Pooling
32296183
Intra
GEM P55040 POF1B Homo sapiens Q8WVV4-1
Validated Y2H
32296183
Intra
GEM P55040 POF1B Homo sapiens Q8WVV4-1
Y2H Array
32296183
Intra
GEM P55040 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
GEM P55040 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
GEM P55040 TGM7 Homo sapiens Q96PF1
Validated Y2H
32296183
Intra
GEM P55040 TGM7 Homo sapiens Q96PF1
Y2H Array
32296183
Intra
GEM P55040 TGM7 Homo sapiens Q96PF1
Y2H Prey Pooling
32296183
Intra
GEM P55040 WWOX Homo sapiens Q9NZC7-5
Y2H Array
32296183
Intra
GEM P55040 WWOX Homo sapiens Q9NZC7-5
Y2H Prey Pooling
32296183
Intra
GEM P55040 WWOX Homo sapiens Q9NZC7-5
Validated Y2H
32296183
Intra
GEM P55040 INSC Homo sapiens Q1MX18
Y2H Prey Pooling
32296183
Intra
GEM P55040 INSC Homo sapiens Q1MX18
Y2H Array
32296183
Intra
GEM P55040 INSC Homo sapiens Q1MX18
Validated Y2H
32296183
Intra
GEM P55040 VPS28 Homo sapiens Q9UK41-2
Validated Y2H
32296183
Intra
GEM P55040 VPS28 Homo sapiens Q9UK41-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 VPS28 Homo sapiens Q9UK41-2
Y2H Array
32296183
Intra
GEM P55040 ANKRD36B Homo sapiens Q8N2N9-4
Validated Y2H
32296183
Intra
GEM P55040 ANKRD36B Homo sapiens Q8N2N9-4
Y2H Array
32296183
Intra
GEM P55040 ANKRD36B Homo sapiens Q8N2N9-4
Y2H Prey Pooling
32296183
Intra
GEM P55040 DBF4B Homo sapiens Q8NFT6-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 DBF4B Homo sapiens Q8NFT6-2
Validated Y2H
32296183
Intra
GEM P55040 DBF4B Homo sapiens Q8NFT6-2
Y2H Array
32296183
Intra
GEM P55040 ZBTB42 Homo sapiens B2RXF5
Y2H Array
32296183
Intra
GEM P55040 ZBTB42 Homo sapiens B2RXF5
Y2H Prey Pooling
32296183
Intra
GEM P55040 NDUFB7 Homo sapiens P17568
Y2H Prey Pooling
32296183
Intra
GEM P55040 NDUFB7 Homo sapiens P17568
Y2H Array
32296183
Intra
GEM P55040 ASB15 Homo sapiens Q8WXK1
Y2H Prey Pooling
32296183
Intra
GEM P55040 ASB15 Homo sapiens Q8WXK1
Y2H Array
32296183
Intra
GEM P55040 ASB15 Homo sapiens Q8WXK1
Validated Y2H
32296183
Intra
GEM P55040 SNAP91 Homo sapiens O60641-3
Y2H Prey Pooling
32296183
Intra
GEM P55040 SNAP91 Homo sapiens O60641-3
Y2H Array
32296183
Intra
GEM P55040 LIMS1 Homo sapiens P48059-3
Y2H Prey Pooling
32296183
Intra
GEM P55040 LIMS1 Homo sapiens P48059-3
Y2H Array
32296183
Intra
GEM P55040 MGLL Homo sapiens A0A0C4DFN3
Y2H Array
32296183
Intra
GEM P55040 MGLL Homo sapiens A0A0C4DFN3
Y2H Prey Pooling
32296183
Intra
GEM P55040 TBC1D3G Homo sapiens Q6DHY5
Y2H Prey Pooling
32296183
Intra
GEM P55040 TBC1D3G Homo sapiens Q6DHY5
Y2H Array
32296183
Intra
GEM P55040 TBC1D3G Homo sapiens Q6DHY5
Validated Y2H
32296183
Intra
GEM P55040 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
GEM P55040 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
GEM P55040 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
GEM P55040 C1orf131 Homo sapiens Q8NDD1-6
Validated Y2H
32296183
Intra
GEM P55040 C1orf131 Homo sapiens Q8NDD1-6
Y2H Array
32296183
Intra
GEM P55040 C1orf131 Homo sapiens Q8NDD1-6
Y2H Prey Pooling
32296183
Intra
GEM P55040 SPATA6 Homo sapiens Q9NWH7-2
Validated Y2H
32296183
Intra
GEM P55040 SPATA6 Homo sapiens Q9NWH7-2
Y2H Array
32296183
Intra
GEM P55040 SPATA6 Homo sapiens Q9NWH7-2
Y2H Prey Pooling
32296183
Intra
GEM P55040 LRP2BP Homo sapiens Q9P2M1
Y2H Array
32296183
Intra
GEM P55040 LRP2BP Homo sapiens Q9P2M1
Validated Y2H
32296183
Intra
GEM P55040 LRP2BP Homo sapiens Q9P2M1
Y2H Prey Pooling
32296183
Intra
GEM P55040 SSX2IP Homo sapiens Q9Y2D8
Y2H Array
25416956
Intra
GEM P55040 SSX2IP Homo sapiens Q9Y2D8
Validated Y2H
25416956
Intra
GEM P55040 MKRN3 Homo sapiens Q13064
Y2H Prey Pooling
32296183
Intra
GEM P55040 MKRN3 Homo sapiens Q13064
Y2H Array
32296183
Intra
GEM P55040 MKRN3 Homo sapiens Q13064
Validated Y2H
32296183
Intra
GEM P55040 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra
GEM P55040 EFHC2 Homo sapiens Q5JST6
Validated Y2H
32296183
Intra
GEM P55040 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra
GEM P55040 AHCYL1 Homo sapiens O43865
Y2H Prey Pooling
32296183
Intra
GEM P55040 AHCYL1 Homo sapiens O43865
Y2H Array
32296183
Intra
GEM P55040 AHCYL1 Homo sapiens O43865
Y2H Prey Pooling
25416956
Intra
GEM P55040 AHCYL1 Homo sapiens O43865
Validated Y2H
25416956
Intra
GEM P55040 TFAP4 Homo sapiens Q01664
Anti Bait CoIP
16924111
Intra
GEM P55040 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
32296183
Intra
GEM P55040 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
GEM P55040 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
25416956
Intra
GEM P55040 BLZF1 Homo sapiens Q9H2G9
Y2H Array
25416956
Intra
GEM P55040 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
GEM P55040 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
32296183
Intra
GEM P55040 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra
GEM P55040 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZNF552 Homo sapiens Q9H707
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZNF552 Homo sapiens Q9H707
Validated Y2H
32296183
Intra
GEM P55040 ZNF552 Homo sapiens Q9H707
Y2H Array
32296183
Intra
GEM P55040 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra
GEM P55040 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
GEM P55040 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
GEM P55040 PLAGL2 Homo sapiens Q9UPG8
Y2H Array
32296183
Intra
GEM P55040 PLAGL2 Homo sapiens Q9UPG8
Y2H Prey Pooling
32296183
Intra
GEM P55040 PLAGL2 Homo sapiens Q9UPG8
Validated Y2H
32296183
Intra
GEM P55040 PNMA1 Homo sapiens Q8ND90
Validated Y2H
25416956
Intra
GEM P55040 PNMA1 Homo sapiens Q8ND90
Y2H Array
25416956
Intra
GEM P55040 CCDC88B Homo sapiens A6NC98
Y2H Array
32296183
Intra
GEM P55040 CCDC88B Homo sapiens A6NC98
Y2H Prey Pooling
32296183
Intra
GEM P55040 MCRS1 Homo sapiens Q96EZ8
Y2H Prey Pooling
32296183
Intra
GEM P55040 MCRS1 Homo sapiens Q96EZ8
Validated Y2H
32296183
Intra
GEM P55040 MCRS1 Homo sapiens Q96EZ8
Y2H Array
32296183
Intra
GEM P55040 PDLIM7 Homo sapiens Q9NR12
Y2H Pooling
16189514
Intra
GEM P55040 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
Intra
GEM P55040 PDLIM7 Homo sapiens Q9NR12
Validated Y2H
32296183
Intra
GEM P55040 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
Intra
GEM P55040 VIM Homo sapiens P08670
Y2H Prey Pooling
32296183
Intra
GEM P55040 VIM Homo sapiens P08670
Y2H Array
32296183
Intra
GEM P55040 TRAF2 Homo sapiens Q12933
Validated Y2H
32296183
Intra
GEM P55040 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
GEM P55040 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
GEM P55040 PIH1D1 Homo sapiens Q9NWS0
Y2H Prey Pooling
32296183
Intra
GEM P55040 PIH1D1 Homo sapiens Q9NWS0
Validated Y2H
32296183
Intra
GEM P55040 PIH1D1 Homo sapiens Q9NWS0
Y2H Array
32296183
Intra
GEM P55040 TRAF1 Homo sapiens Q13077
Validated Y2H
25416956
Intra
GEM P55040 TRAF1 Homo sapiens Q13077
Validated Y2H
32296183
Intra
GEM P55040 TRAF1 Homo sapiens Q13077
Y2H Array
25416956
Intra
GEM P55040 TRAF1 Homo sapiens Q13077
Y2H Array
32296183
Intra
GEM P55040 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
32296183
Intra
GEM P55040 YWHAB Homo sapiens P31946
CoIP
14701738
Intra
GEM P55040 YWHAB Homo sapiens P31946
Pull Down
30833792
Intra
GEM P55040 EXOSC8 Homo sapiens Q96B26
Validated Y2H
32296183
Intra
GEM P55040 EXOSC8 Homo sapiens Q96B26
Y2H Array
32296183
Intra
GEM P55040 EXOSC8 Homo sapiens Q96B26
Y2H Prey Pooling
32296183
Intra
GEM P55040 GADD45GIP1 Homo sapiens Q8TAE8
Y2H Array
32296183
Intra
GEM P55040 GADD45GIP1 Homo sapiens Q8TAE8
Y2H Prey Pooling
32296183
Intra
GEM P55040 GADD45GIP1 Homo sapiens Q8TAE8
Validated Y2H
32296183
Intra
GEM P55040 COG6 Homo sapiens Q9Y2V7
Y2H Array
32296183
Intra
GEM P55040 COG6 Homo sapiens Q9Y2V7
Validated Y2H
32296183
Intra
GEM P55040 COG6 Homo sapiens Q9Y2V7
Y2H Prey Pooling
32296183
Intra
GEM P55040 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
GEM P55040 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
GEM P55040 MYOG Homo sapiens P15173
Y2H Array
32296183
Intra
GEM P55040 MYOG Homo sapiens P15173
Y2H Prey Pooling
32296183
Intra
GEM P55040 PRDM14 Homo sapiens Q9GZV8
Validated Y2H
32296183
Intra
GEM P55040 PRDM14 Homo sapiens Q9GZV8
Y2H Prey Pooling
32296183
Intra
GEM P55040 PRDM14 Homo sapiens Q9GZV8
Y2H Array
32296183
Intra
GEM P55040 SPAG5 Homo sapiens Q96R06
Validated Y2H
32296183
Intra
GEM P55040 SPAG5 Homo sapiens Q96R06
Y2H Prey Pooling
32296183
Intra
GEM P55040 SPAG5 Homo sapiens Q96R06
Y2H Array
32296183
Intra
GEM P55040 ZNF688 Homo sapiens P0C7X2
Y2H Array
32296183
Intra
GEM P55040 ZNF688 Homo sapiens P0C7X2
Y2H Prey Pooling
32296183
Intra
GEM P55040 KCTD9 Homo sapiens Q7L273
Y2H Prey Pooling
32296183
Intra
GEM P55040 KCTD9 Homo sapiens Q7L273
Validated Y2H
32296183
Intra
GEM P55040 KCTD9 Homo sapiens Q7L273
Y2H Array
25416956
Intra
GEM P55040 KCTD9 Homo sapiens Q7L273
Y2H Array
32296183
Intra
GEM P55040 BLOC1S2 Homo sapiens Q6QNY1
Y2H Prey Pooling
32296183
Intra
GEM P55040 BLOC1S2 Homo sapiens Q6QNY1
Y2H Array
32296183
Intra
GEM P55040 BLOC1S2 Homo sapiens Q6QNY1
Validated Y2H
32296183
Intra
GEM P55040 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
GEM P55040 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
GEM P55040 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra
GEM P55040 TCF4 Homo sapiens P15884
Y2H Array
25416956
Intra
GEM P55040 TCF4 Homo sapiens P15884
Y2H Prey Pooling
25416956
Intra
GEM P55040 OIP5 Homo sapiens O43482
Y2H Prey Pooling
32296183
Intra
GEM P55040 OIP5 Homo sapiens O43482
Y2H Array
32296183
Intra
GEM P55040 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
GEM P55040 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
GEM P55040 MESD Homo sapiens Q14696
Y2H Prey Pooling
32296183
Intra
GEM P55040 MESD Homo sapiens Q14696
Validated Y2H
32296183
Intra
GEM P55040 MESD Homo sapiens Q14696
Y2H Array
32296183
Intra
GEM P55040 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra
GEM P55040 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
Intra
GEM P55040 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra
GEM P55040 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
GEM P55040 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
GEM P55040 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
Intra
GEM P55040 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
GEM P55040 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
GEM P55040 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
GEM P55040 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
Intra
GEM P55040 KRT6A Homo sapiens P02538
Y2H Prey Pooling
32296183
Intra
GEM P55040 KRT6A Homo sapiens P02538
Y2H Array
32296183
Intra
GEM P55040 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
GEM P55040 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
GEM P55040 ECSIT Homo sapiens Q9BQ95
Y2H Prey Pooling
32296183
Intra
GEM P55040 ECSIT Homo sapiens Q9BQ95
Validated Y2H
32296183
Intra
GEM P55040 ECSIT Homo sapiens Q9BQ95
Y2H Array
32296183
Intra
GEM P55040 KATNBL1 Homo sapiens Q9H079
Y2H Prey Pooling
32296183
Intra
GEM P55040 KATNBL1 Homo sapiens Q9H079
Validated Y2H
32296183
Intra
GEM P55040 KATNBL1 Homo sapiens Q9H079
Y2H Array
32296183
Intra
GEM P55040 ZNF20 Homo sapiens P17024
Y2H Array
32296183
Intra
GEM P55040 ZNF20 Homo sapiens P17024
Y2H Prey Pooling
32296183
Intra
GEM P55040 TRIM27 Homo sapiens P14373
Y2H Array
25416956
Intra
GEM P55040 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra
GEM P55040 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
25416956
Intra
GEM P55040 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra
GEM P55040 COG8 Homo sapiens Q96MW5
Y2H Prey Pooling
25416956
Intra
GEM P55040 COG8 Homo sapiens Q96MW5
Validated Y2H
25416956
Intra
GEM P55040 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
GEM P55040 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
GEM P55040 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
GEM P55040 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
GEM P55040 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra
GEM P55040 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra
GEM P55040 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
32296183
Intra
GEM P55040 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
GEM P55040 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
GEM P55040 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
GEM P55040 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
32296183
Intra
GEM P55040 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra
GEM P55040 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra
GEM P55040 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
32296183
Intra
GEM P55040 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra
GEM P55040 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra
GEM P55040 BEGAIN Homo sapiens Q9BUH8
Y2H Prey Pooling
32296183
Intra
GEM P55040 BEGAIN Homo sapiens Q9BUH8
Validated Y2H
32296183
Intra
GEM P55040 BEGAIN Homo sapiens Q9BUH8
Y2H Array
32296183
Intra
GEM P55040 TRIM32 Homo sapiens Q13049
Y2H Prey Pooling
32296183
Intra
GEM P55040 TRIM32 Homo sapiens Q13049
Validated Y2H
32296183
Intra
GEM P55040 TRIM32 Homo sapiens Q13049
Y2H Array
32296183
Intra
GEM P55040 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra
GEM P55040 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
GEM P55040 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
GEM P55040 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
25416956
Intra
GEM P55040 RUNDC3A Homo sapiens Q59EK9
Y2H Prey Pooling
25416956
Intra
GEM P55040 ZC4H2 Homo sapiens Q9NQZ6
Validated Y2H
32296183
Intra
GEM P55040 ZC4H2 Homo sapiens Q9NQZ6
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZC4H2 Homo sapiens Q9NQZ6
Y2H Array
32296183
Intra
GEM P55040 DEUP1 Homo sapiens Q05D60
Y2H Array
25416956
Intra
GEM P55040 DEUP1 Homo sapiens Q05D60
Y2H Prey Pooling
25416956
Intra
GEM P55040 ZSCAN9 Homo sapiens O15535
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZSCAN9 Homo sapiens O15535
Y2H Array
32296183
Intra
GEM P55040 INO80E Homo sapiens Q8NBZ0
Y2H Array
32296183
Intra
GEM P55040 INO80E Homo sapiens Q8NBZ0
Y2H Prey Pooling
25416956
Intra
GEM P55040 INO80E Homo sapiens Q8NBZ0
Y2H Prey Pooling
32296183
Intra
GEM P55040 INO80E Homo sapiens Q8NBZ0
Validated Y2H
25416956
Intra
GEM P55040 INO80E Homo sapiens Q8NBZ0
Validated Y2H
32296183
Intra
GEM P55040 ZMAT5 Homo sapiens Q9UDW3
Y2H Array
32296183
Intra
GEM P55040 ZMAT5 Homo sapiens Q9UDW3
Y2H Prey Pooling
32296183
Intra
GEM P55040 ZMAT5 Homo sapiens Q9UDW3
Validated Y2H
32296183
Intra
GEM P55040 USH1G Homo sapiens Q495M9
Validated Y2H
32296183
Intra
GEM P55040 USH1G Homo sapiens Q495M9
Y2H Array
32296183
Intra
GEM P55040 USH1G Homo sapiens Q495M9
Y2H Prey Pooling
32296183
Intra
GEM P55040 IHO1 Homo sapiens Q8IYA8
Validated Y2H
32296183
Intra
GEM P55040 IHO1 Homo sapiens Q8IYA8
Y2H Prey Pooling
32296183
Intra
GEM P55040 IHO1 Homo sapiens Q8IYA8
Y2H Array
32296183
Intra
GEM P55040 NOTCH2NLA Homo sapiens Q7Z3S9
Y2H Array
25416956
Intra
GEM P55040 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
Intra
GEM P55040 CACNB1 Homo sapiens Q02641
Anti Tag CoIP
17052716
Intra
GEM P55040 CACNB1 Homo sapiens Q02641
Anti Tag CoIP
35122502
Intra
GEM P55040 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
GEM P55040 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
GEM P55040 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
GEM P55040 MORN3 Homo sapiens Q6PF18
Validated Y2H
32296183
Intra
GEM P55040 MORN3 Homo sapiens Q6PF18
Y2H Array
32296183
Intra
GEM P55040 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
32296183
Cross
GEM P55040 CACNA1A Oryctolagus cuniculus P27884
Anti Tag CoIP
20679232
Cross
GEM P55040 Cacnb3 Rattus norvegicus P54287
Anti Tag CoIP
20679232
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149906 Trecovirsen Inhibitor / Unkown
HY-149906C Trecovirsen sodium Inhibitor 98.83% Unkown
HY-143411 GEM144 / Unkown
HY-145314 TC113 / Unkown
HY-145441 GEM–IB / Unkown
HY-146540 GEM-5 / Unkown
HY-148827 GEM-231 Inhibitor / Unkown
HY-148827A GEM-231 sodium Inhibitor / Unkown
HY-149906A FITC-Trecovirsen sodium Inhibitor / Unkown
HY-154842 S-Gem / Unkown
HY-154843 C-Gem / Unkown
HY-RS05366 GEM Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GEM MGD MGI:99844
Bos taurus GEM VGNC VGNC:29315
Rattus norvegicus GEM RGD RGD:1307386
Canis familiaris GEM VGNC VGNC:41172
Felis catus GEM VGNC VGNC:62512
Susscrofa domestica GEM NCBI
Macaca mulatta GEM NCBI NCBI:699130
Others GEM NCBI