TMEM51 - transmembrane protein 51 Gene

Homo sapiens

Also known as C1orf72

Gene ID: 55092 | Gene type: protein coding

About TMEM51

This gene has 6 transcripts (splice variants) and 269 orthologues. Ubiquitous expression in urinary bladder (RPKM 10.5), gall bladder (RPKM 9.1) and 24 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM51 Products(5)

mRNA	Protein	Name
NM_001136216.2	NP_001129688.1	transmembrane protein 51 isoform 1
NM_001136217.2	NP_001129689.1	transmembrane protein 51 isoform 1
NM_001136218.2	NP_001129690.1	transmembrane protein 51 isoform 1
NM_001319665.2	NP_001306594.1	transmembrane protein 51 isoform 2
NM_018022.3	NP_060492.1	transmembrane protein 51 isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM51 Protein Structure

TMEM51

0
100
200
253 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 51

TMEM51 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TMEM51	Q9NW97	TMEM242	Homo sapiens	Q9NWH2	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	TMEM242	Homo sapiens	Q9NWH2	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	TMEM242	Homo sapiens	Q9NWH2	Y2H Array	32296183
Intra	TMEM51	Q9NW97	NINJ2	Homo sapiens	Q9NZG7	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	PTPN5	Homo sapiens	P54829	Validated Y2H	25416956
Intra	TMEM51	Q9NW97	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	TMEM51	Q9NW97	ITCH	Homo sapiens	Q96J02	Anti Tag CoIP	28514442
Intra	TMEM51	Q9NW97	ITCH	Homo sapiens	Q96J02	Anti Tag CoIP	33961781
Intra	TMEM51	Q9NW97	GET3	Homo sapiens	O43681	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	TMEM14A	Homo sapiens	Q9Y6G1	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	EMP3	Homo sapiens	P54852	PLA	30614533
Intra	TMEM51	Q9NW97	EMP3	Homo sapiens	P54852	BiFC	30614533
Intra	TMEM51	Q9NW97	EBP	Homo sapiens	Q15125	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	EBP	Homo sapiens	Q15125	Y2H Array	32296183
Intra	TMEM51	Q9NW97	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	VTI1B	Homo sapiens	Q9UEU0	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	NEDD4	Homo sapiens	P46934	Anti Tag CoIP	33961781
Intra	TMEM51	Q9NW97	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
Intra	TMEM51	Q9NW97	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
Intra	TMEM51	Q9NW97	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	TMEM51	Q9NW97	CCDC167	Homo sapiens	Q9P0B6	Validated Y2H	32296183
Intra	TMEM51	Q9NW97	UBE2J1	Homo sapiens	Q9Y385	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14730	TMEM51 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TMEM51	VGNC	VGNC:47586
Bos taurus	TMEM51	VGNC	VGNC:36094
Rattus norvegicus	TMEM51	RGD	RGD:1565452
Mus musculus	TMEM51	MGD	MGI:2384874
Felis catus	TMEM51	VGNC	VGNC:107680
Macaca mulatta	TMEM51	VGNC	VGNC:79501

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