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Results for "

Crosslinker

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA Alkylator/Crosslinker (9) ADC Linker (19) Amino Acid Derivatives (1) Bacterial (1) Biochemical Assay Reagents (54) Casein Kinase (1) Caspase (1) DNA/RNA Synthesis (1) Drug-Linker Conjugates for ADC (2) E3 Ligase Ligand-Linker Conjugates (3) Endogenous Metabolite (1) Fluorescent Dye (1) Isotope-Labeled Compounds (5) MDM-2/p53 (1) Microtubule/Tubulin (1) Parasite (1) Peptide-Drug Conjugates (PDCs) (1) PROTAC Linkers (4) Topoisomerase (1)
By Research Areas:	Cancer (40) Cardiovascular Disease (2) Endocrinology (2) Infection (2) Inflammation/Immunology (5) Metabolic Disease (1)
Click Chemistry:	ADC Synthesis (1) DBCO (1) PROTAC Synthesis (2) Azide (6) Alkynes (1)

105

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: DNA Alkylator/Crosslinker

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W264744

3-Maleimidobenzoic acid	Biochemical Assay Reagents	Others
3-Maleimidobenzoic acid is a protein crosslinker .

HY-120937

DC4 Crosslinker	Biochemical Assay Reagents	Others
DC4 Crosslinker is a stable crosslinking reagent with improved activity and solubility. DC4 Crosslinker is labile cleavable with collision-induced dissociation (CID), that will be fragmented into four rearrange products containing mobilized protons .

HY-126349

DTSSP Crosslinker	ADC Linker	Cancer
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-144337

*DNA crosslinker* 4 dihydrochloride**	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 4 (dihydrochloride) is a potent DNA minor groove binder. DNA crosslinker 4 (dihydrochloride) has certain inhibitory activity against cancer cells NCI-H460, A2780 and MCF-7. DNA crosslinker 4 (dihydrochloride) can be used for researching anticancer .

HY-144335

*DNA crosslinker* 2 dihydrochloride**	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 2 (dihydrochloride) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.2 °C. DNA crosslinker 2 (dihydrochloride) has certain inhibitory activity against cancer cells NCI-H460, A2780 and MCF-7. DNA crosslinker 2 (dihydrochloride) can be used for researching anticancer .

HY-144336

*DNA crosslinker* 3 dihydrochloride**	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 3 (dihydrochloride) (compound 1) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.4 °C. DNA crosslinker 3 (dihydrochloride) can be used for researching anticancer .

HY-144333

*DNA crosslinker* 1 dihydrochloride**	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 1 dihydrochloride (Compound 4) is a potent DNA minor groove binder with DNA binding affinity (ΔT_m) of 1.1 °C. DNA crosslinker 1 dihydrochloride can be used for researching anticancer .

HY-168619

*DNA crosslinker* 6**	Parasite	Infection Cancer
DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC₅₀=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC₅₀ value of 0.83 µM for the inhibition of T. brucei .

HY-W096122

*DTSSP Crosslinker* disodium**	Biochemical Assay Reagents	Others
DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity .

HY-124318

SMPH Crosslinker	PROTAC Linkers	Cancer
SMPH Crosslinker is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-118759

DSP Crosslinker 1 Publications Verification	ADC Linker	Inflammation/Immunology
DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs) .

HY-118759S

*DSP Crosslinker-d8*	Isotope-Labeled Compounds	Others
DSP Crosslinker-d₈ is the deuterium labeled DSP Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-111434

*UAA crosslinker* 1**	Biochemical Assay Reagents	Cancer
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases . UAA crosslinker 1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-111434A

*UAA crosslinker* 1 hydrochloride**	Biochemical Assay Reagents	Cancer
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases . UAA crosslinker 1 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-157414

Azide-A-DSBSO crosslinker	Others	Others
Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS) .

HY-W019543

Disuccinimidyl suberate Crosslinker 5 Publications Verification	ADC Linker	Cancer
Disuccinimidyl suberate Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-124329

BS3 Crosslinker	ADC Linker	Cancer
BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W705390

*Disuccinimidyl suberate Crosslinker-d4*	Isotope-Labeled Compounds	Others
Disuccinimidyl suberate Crosslinker-d₄ is the deuterium labeled Disuccinimidyl suberate Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-114697

DSG Crosslinker 1 Publications Verification Disuccinimidyl glutarate	ADC Linker	Inflammation/Immunology
DSG Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-124329AS

*BS3 Crosslinker-d4 disodium*	Isotope-Labeled Compounds	Others
BS3 Crosslinker-d₄ (disodium) is the deuterium labeled BS3 Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-124329A

*BS3 Crosslinker* disodium**	ADC Linker	Cancer
BS3 Crosslinker disodium is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W332335

Sulfosuccinimidyl-6-(biotinamido)hexanoate sodium	Biochemical Assay Reagents	Others
Sulfosuccinimidyl-6-(biotinamido)hexanoate sodium is a protein crosslinker, and is a biotinylation reagentcan for labeling cell surface proteins .

HY-130547S

*BS2G Crosslinker-d4 disodium*	Isotope-Labeled Compounds	Others
BS2G Crosslinker-d₄ (disodium) is the deuterium labeled BS2G Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-130547

*BS2G Crosslinker* disodium**	ADC Linker	Cancer
BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-100216

SPDP 5 Publications Verification SPDP Crosslinker; Py-ds-Prp-OSu	ADC Linker	Cancer
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .

HY-W011541

SIA Crosslinker Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate	ADC Linker	Cancer
SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-114697S

*DSG Crosslinker-d4* Disuccinimidyl glutarate-d₄	Isotope-Labeled Compounds	Others
DSG Crosslinker-d₄ is the deuterium labeled DSG Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-W319374

2-(Methylsulfonyl)ethyl n-succinimidyl carbonate	Biochemical Assay Reagents	Others
2-(Methylsulfonyl)ethyl n-succinimidyl carbonate is a protein crosslinker. 2-(Methylsulfonyl)ethyl n-succinimidyl carbonate has amino protective function .

HY-140051

N-Boc-aminoxy-PEG3-propargyl t-Boc-aminooxy-PEG3-Propargyl	ADC Linker	Cancer
N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC .

HY-145485

HS-PEG-SH (MW 3400)	Biochemical Assay Reagents	Others
HS-PEG-SH (MW 3400), a linear homobifunctional PEG, is a cross-linker. HS-PEG-SH can be used for drug delivery and preparation of PEG hydrogels .

HY-142740

Rha-PEG3-SMCC	Drug-Linker Conjugates for ADC	Cancer
Rha-PEG3-SMCC (compound 13) is a agent-linker conjugate for ADC with potent antitumor activity by using SMCC (a protein crosslinker), linked via the noncleavable ADC linker Rha-PEG3.

HY-150014

AMT-NHS	Others	Others
AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .

HY-103700A

Azide-phenylalanine hydrochloride UAA Crosslinker 2	Amino Acid Derivatives	Others
Azide-phenylalanine hydrochloride is a phenylalanine derivative. Azide-phenylalanine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130458

EGNHS 2 Publications Verification EGS Crosslinker	PROTAC Linkers	Cancer
EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-135066

Triallyl pentaerythritol Pentaerythritol triallyl ether	Biochemical Assay Reagents	Others
Triallyl pentaerythritol (PEATA), a crosslinker, decreases the protein rejection compared to membranes functionalized with MBAA or without any crosslinker .

HY-130547A

BS2G Crosslinker	DNA Alkylator/Crosslinker

HY-W123009

Sulfo-KMUS sodium salt 11-Maleimidoundecanoic acid sulfo-N-succinimidyl ester sodium salt	Biochemical Assay Reagents	Others
Sulfo-KMUS (sodium salt) acts as a crosslinker .

HY-129377

Sulfo-SPP	ADC Linker	Cancer
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-129377A

Sulfo-SPP sodium	ADC Linker	Cancer
Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-136772

Pomalidomide-PEG1-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand .

HY-137383

Sulfo-SANPAH	Biochemical Assay Reagents	Cardiovascular Disease
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker .

HY-126503

trans-Sulfo-SMCC	ADC Linker	Cancer
trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.

HY-126495

Sulfo-LC-SPDP	ADC Linker	Cancer
Sulfo-LC-SPDP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-172384

Glycerol ethoxylate	Biochemical Assay Reagents	Others
Glycerol ethoxylate is a crosslinker for polyesters and polyester ethers. Glycerol ethoxylate can be used as an ignition improver .

HY-119523

Disuccinimidyl sebacate 2 Publications Verification DSSeb; Sebacic acid bis N-succinimidyl ester	Biochemical Assay Reagents	Others
Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .

HY-128925

AMAS 1 Publications Verification	ADC Linker	Cancer
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.

HY-W123005

Dimethyl pimelimidate dihydrochloride	Biochemical Assay Reagents	Others
Dimethyl pimelimidate dihydrochloride (DMP) is a protein crosslinker that can be used in chromatin immunoprecipitation experiments (ChIP) to enhance signal .

HY-W104848

4-Maleimidobenzoic acid	Biochemical Assay Reagents	Others
4-Maleimidobenzoic acid is a protein crosslinker. 4-Maleimidobenzoic acid can be used to synthesis maleimidobenzoyl spacers .

HY-42360

SMCC	ADC Linker	Cancer
SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .

HY-168937A

HS-PEG-NH2 (Mn 5000)	Biochemical Assay Reagents	Others
HS-PEG-NH2 (Mn 5000) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

Cat. No.	Product Name	Type

HY-D2396

Sulfo SMCC R-phycoerythrin Sulfo SMCC R-PE	Dyes
Sulfo SMCC R-phycoerythrin is a conjugate composed of the protein crosslinker SMCC (HY-42360) and R-PE (R-Phycoerythrin) (HY-D0988) that can be used to label proteins to make them carry red fluorescence. Among them, SMCC is able to engage antigen-coupled spleen cells to induce antigen-specific immune responses .

Cat. No.	Product Name	Type

HY-W123009

Sulfo-KMUS sodium salt 11-Maleimidoundecanoic acid sulfo-N-succinimidyl ester sodium salt	Biochemical Assay Reagents
Sulfo-KMUS (sodium salt) acts as a crosslinker .

HY-172384

Glycerol ethoxylate	3D Bioprinting
Glycerol ethoxylate is a crosslinker for polyesters and polyester ethers. Glycerol ethoxylate can be used as an ignition improver .

HY-168937A

HS-PEG-NH2 (Mn 5000)	3D Bioprinting
HS-PEG-NH2 (Mn 5000) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168937B

HS-PEG-NH2 (Mn 3500)	3D Bioprinting
HS-PEG-NH2 (Mn 3500) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168937C

HS-PEG-NH2 (Mn 7500)	3D Bioprinting
HS-PEG-NH2 (Mn 7500) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168937

HS-PEG-NH2 (Mn 2000)	3D Bioprinting
HS-PEG-NH2 (Mn 2000) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168940B

NH2-PEG-COOH (Mn 2000)	3D Bioprinting
NH2-PEG-COOH (Mn 2000) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168940A

NH2-PEG-COOH (Mn 3500)	3D Bioprinting
NH2-PEG-COOH (Mn 3500) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-130601

Thiol-PEG5-thiol Bis-PEG5-thiol	3D Bioprinting
Thiol-PEG5-thiol (Bis-PEG5-thiol) is a bifunctional thiol cross-linker agent.

HY-168940

NH2-PEG-COOH (Mn 1100)	3D Bioprinting
NH2-PEG-COOH (Mn 1100) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-168940C

NH2-PEG-COOH (Mn 10100)	3D Bioprinting
NH2-PEG-COOH (Mn 10100) is a bifunctional cross-linker that can be used to synthesize PEG hydrogels .

HY-W017588

N-(2-Hydroxyethyl)maleimide	Biochemical Assay Reagents
N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis .

HY-135963

Thiol-PEG3-thiol Bis-PEG3-thiol	3D Bioprinting
Thiol-PEG3-thiol (Bis-PEG3-thiol) is a thiol crosslinker used in the synthesis of PEG hydrogels.

HY-D0975

Sulfo-SMCC sodium 4 Publications Verification	Biochemical Assay Reagents
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

HY-168939A

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000)	3D Bioprinting
Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .

HY-168939

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000)	3D Bioprinting
Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .

HY-168939C

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000)	3D Bioprinting
Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .

HY-168939B

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400)	3D Bioprinting
Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .

HY-W068119A

N-(2-Aminoethyl)maleimide hydrochloride 2-Maleimidoethylamine hydrochloride	Biochemical Assay Reagents
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a cross-linker. N-(2-Aminoethyl)maleimide hydrochloride can be used to prepare MMP-2 sensitive nanosystem, and for cancer research .

HY-D0848

N,N'-Methylenebisacrylamide

Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide

Thickeners

N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel .

HY-125865

Casein

Native Proteins

Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α₂-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .

Cat. No.	Product Name	Target	Research Area

HY-P3159

VPM peptide	Biochemical Assay Reagents	Others
VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-P3159A

VPM peptide TFA	Biochemical Assay Reagents	Others
VPM peptide TFA is a dithiol protease-cleavable peptide cross-linker. VPM peptide TFA can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .

HY-P10765

DTS-108	Peptide-Drug Conjugates (PDCs) Topoisomerase	Cancer
DTS-108 is a prodrug of SN38 (HY-13704) (a Topoisomerase I inhibitor). DTS-108 is a conjugate generated by linking SN38 to a human oligopeptide via an esterase sensitive cross-linker. DTS-108 exhibits anti-tumor activity against colorectal, lung, and mammary cancer .

Cat. No.	Product Name	Chemical Structure

HY-118759S

*DSP Crosslinker-d8*
DSP Crosslinker-d₈ is the deuterium labeled DSP Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-W705390

*Disuccinimidyl suberate Crosslinker-d4*
Disuccinimidyl suberate Crosslinker-d₄ is the deuterium labeled Disuccinimidyl suberate Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-124329AS

*BS3 Crosslinker-d4 disodium*
BS3 Crosslinker-d₄ (disodium) is the deuterium labeled BS3 Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-130547S

*BS2G Crosslinker-d4 disodium*
BS2G Crosslinker-d₄ (disodium) is the deuterium labeled BS2G Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-114697S

*DSG Crosslinker-d4*
DSG Crosslinker-d₄ is the deuterium labeled DSG Crosslinker. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

Cat. No.	Product Name		Classification

HY-111434

*UAA crosslinker* 1**		Azide
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases . UAA crosslinker 1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-111434A

*UAA crosslinker* 1 hydrochloride**		Azide
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases . UAA crosslinker 1 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-140051

N-Boc-aminoxy-PEG3-propargyl t-Boc-aminooxy-PEG3-Propargyl		Alkynes
N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC .

HY-103700A

Azide-phenylalanine hydrochloride UAA Crosslinker 2		Azide
Azide-phenylalanine hydrochloride is a phenylalanine derivative. Azide-phenylalanine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W457953

tert-Butyl N-(4-azidobutyl)carbamate		Azide
tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-130435

DBCO-PEG4-amine		ADC Synthesis DBCO PROTAC Synthesis
DBCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker) . DBCO-PEG4-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-151792

Pomalidomid-C6-PEG3-butyl-N3		Azide PROTAC Synthesis
Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. Pomalidomid-C6-PEG3-butyl-N3 also is a crosslinker-E3 ligase ligand conjugate, which be used in click reactive protein degrader building block for PROTAC research. Pomalidomid-C6-PEG3-butyl-N3 also can be used in the template for synthesis of targeted protein degrader . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151791

(S,R,S)-AHPC-C6-PEG3-butyl-N3		Azide
(S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S,R,S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate . (S,R,S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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