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Results for "

Elongation

" in MedChemExpress (MCE) Product Catalog:

76

Inhibitors & Agonists

3

Peptides

24

Natural
Products

6

Recombinant Proteins

8

Isotope-Labeled Compounds

10

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1350
    Fusidic acid
    2 Publications Verification

    Fusidate; SQ-16603

    Bacterial Antibiotic Infection Cancer
    Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome .
    Fusidic acid
  • HY-145880

    Bacterial Infection
    Elongation factor P-IN-1 is a potent inhibitor elongation factor P (EFP). Elongation factor P-IN-1 is a β-lysine derivative compound. Elongation factor P-IN-1 affects the proliferation rates of E. coli .
    Elongation factor P-IN-1
  • HY-145881

    Bacterial Infection
    Elongation factor P-IN-2 is a potent inhibitor elongation factor P (EFP). Elongation factor P-IN-2 is a β-lysine derivative compound. Elongation factor P-IN-2 affects the proliferation rates of E. coli .
    Elongation factor P-IN-2
  • HY-N10290

    Others Others
    Cytochalasin K (Compounds 7) is a cytochalasin that inhibits wheat root elongation with an IC50 of 22.58 μM .
    Cytochalasin K
  • HY-137868

    Decanoyl-coa

    Endogenous Metabolite Endocrinology
    Decanoyl coenzyme A (Decanoyl CoA) is a primer for the fatty acid elongation system in Mycobacterium smegmat .
    Decanoyl coenzyme A
  • HY-N10291

    Others Others
    10-Phenyl-[12]-cytochalasins Z16 (Compounds 5) is a cytochalasin that inhibits wheat root elongation with an IC50 of 17.35 μM .
    10-Phenyl-[12]-cytochalasins Z16
  • HY-N10230

    Phanerosporic Acid

    Bacterial Infection
    MC 304 is a β-resorcylate isolated from cultures of Phanerochaete chrysosporium. MC 304 has antibacterial activity. MC 304 shows a stimulatory effect on root elongation of Lepidium satiuum .
    MC 304
  • HY-119435

    Others Others
    Triallate is a selective preemergence herbicide for the control of wild oats in barley, spring wheat, Durum wheat, winter wheat, and sugar beets. Triallate inhibits fatty acid elongation and surface lipid (wax) biosynthesis .
    Triallate
  • HY-B1350R

    Fusidate (Standard); SQ-16603 (Standard)

    Antibiotic Bacterial Cancer
    Fusidic acid (Standard) is the analytical standard of Fusidic acid. This product is intended for research and analytical applications. Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome .
    Fusidic acid (Standard)
  • HY-B1350AR

    Bacterial Antibiotic Infection Cancer
    Fusidic acid (sodium salt) (Standard) is the analytical standard of Fusidic acid (sodium salt). This product is intended for research and analytical applications. Fusidic acid sodium salt (Sodium fusidate), a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid sodium salt has no corticosteroid effects. Fusidic acid sodium salt inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome .
    Fusidic acid sodium salt (Standard)
  • HY-119435R

    Others Others
    Triallate (Standard) is the analytical standard of Triallate. This product is intended for research and analytical applications. Triallate is a selective preemergence herbicide for the control of wild oats in barley, spring wheat, Durum wheat, winter wheat, and sugar beets. Triallate inhibits fatty acid elongation and surface lipid (wax) biosynthesis .
    Triallate (Standard)
  • HY-B1350A
    Fusidic acid sodium salt
    2 Publications Verification

    Sodium fusidate; SQ-16360

    Bacterial Antibiotic Interleukin Related Infection Inflammation/Immunology
    Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice .
    Fusidic acid sodium salt
  • HY-P3103

    DNA/RNA Synthesis Cancer
    PINT-87aa, an 87-amino acid (aa) peptide, is encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT). PINT-87aa directly interacts with polymerase associated factor complex (PAF1c) and inhibits the transcriptional elongation of multiple oncogenes. PINT-87aa suppresses glioblastoma cell proliferation in vitro and in vivo .
    PINT-87aa
  • HY-P3103A

    DNA/RNA Synthesis Cancer
    PINT-87aa TFA, an 87-amino acid (aa) peptide, is encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT). PINT-87aa TFA directly interacts with polymerase associated factor complex (PAF1c) and inhibits the transcriptional elongation of multiple oncogenes. PINT-87aa TFA suppresses glioblastoma cell proliferation in vitro and in vivo .
    PINT-87aa TFA
  • HY-B0862S

    Isotope-Labeled Compounds Others
    Pendimethalin-d5 is the deuterium labeled Pendimethalin[1]. Pendimethalin is an herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin inhibits cell division and cell elongation[2].
    Pendimethalin-d5
  • HY-N0273

    Brassin lactone

    Apoptosis Cancer
    Brassinolide is a predominant plant growth modulator that regulate plant cell elongation.
    Brassinolide
  • HY-121231

    Others Others
    trans-Caffeic acid is a growth stimulator that enhances the elongation growth of coleoptile sections .
    trans-Caffeic acid
  • HY-137868A

    Decanoyl-COA triammonium; 10:0 Coenzyme A

    Endogenous Metabolite Endocrinology
    Decanoyl coenzyme A (Decanoyl CoA) triammonium is a primer for the fatty acid elongation system in Mycobacterium smegmat .
    Decanoyl coenzyme A triammonium
  • HY-14944
    Homoharringtonine
    Maximum Cited Publications
    24 Publications Verification

    Omacetaxine mepesuccinate; HHT

    STAT Cancer
    Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
    Homoharringtonine
  • HY-116690

    Others Others
    Daimuron is a herbicide safener. Daimuron has a protective effect against the inhibition of seed root elongation by chloroacetanilide herbicides .
    Daimuron
  • HY-N9128

    Others Others
    Medicarpin 3-O-glucoside a phytoalexin, shows inhibition against the germination of G. intraradices spores and hyphal elongation .
    Medicarpin 3-O-glucoside
  • HY-138165

    Others Others
    Ac-Phe-NH2 is a non-competitive inhibitor of polyubiquitin chain elongation at Ki value of 8 mM by destabilizing the active trimer .
    Ac-Phe-NH2
  • HY-117730

    Antibiotic 1063Z

    Others Infection
    Pulvomycin (Antibiotic 1063Z) is an antibiotic with protein biosynthesis inhibitory activity. Pulvomycin is able to block protein biosynthesis in Bacillus brevis grown in cells. Pulvomycin is highly sensitive to poly(Phe) synthesis in cell-free systems. Pulvomycin does not affect the transfer of phenylalanine to tRNA. Studies have shown that the target of Pulvomycin is the elongation of the polypeptide chain. Pulvomycin can also prevent the formation of a ternary complex between the elongation factor Tu, GTP and aminoacyl-tRNA .
    Pulvomycin
  • HY-134665

    Flavivirus Dengue virus DNA/RNA Synthesis Infection
    NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly .
    NITD-2
  • HY-125572

    GA7

    Others Others
    Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells .
    Gibberellin A7
  • HY-121231R

    Others Others
    trans-Caffeic acid (Standard) is the analytical standard of trans-Caffeic acid. This product is intended for research and analytical applications. trans-Caffeic acid is a growth stimulator that enhances the elongation growth of coleoptile sections .
    trans-Caffeic acid (Standard)
  • HY-10240
    Mericitabine
    5+ Cited Publications

    RG 7128; R-7128; PSI 6130 diisobutyrate

    HCV Infection
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
    Mericitabine
  • HY-122386

    Mocimycin; Delvomycin

    Bacterial Antibiotic Infection
    Kirromycin (Mocimycin) is an antibiotic produced by Streptomyces collinus Tu 365. Kirromycin is a bacterial protein synthesis inhibitor that immobilizes elongation factor Tu (EF-Tu) on the elongating ribosome .
    Kirromycin
  • HY-N3938

    Others Neurological Disease
    Gelsemiol is the main active ingredient in Verbena littoralis H. B. K.. Gelsemiol enhanced nerve growth factor (NGF) -induced axonal elongation in PC12D cells .
    Gelsemiol
  • HY-14944R

    STAT Cancer
    Homoharringtonine (Standard) is the analytical standard of Homoharringtonine. This product is intended for research and analytical applications. Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
    Homoharringtonine (Standard)
  • HY-A0155

    Antibiotic Bacterial Cancer
    Viomycin is a potent antibiotic against Mycobacteria. Viomycin rapidly inhibits polypeptide chain elongation when added to purified endogenous Escherichia coli polysomes actively engaged in polypeptide synthesis .
    Viomycin
  • HY-B0862R

    Others Others
    Pendimethalin (Standard) is the analytical standard of Pendimethalin. This product is intended for research and analytical applications. Pendimethalin is an herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin inhibits cell division and cell elongation .
    Pendimethalin (Standard)
  • HY-123972
    SEC inhibitor KL-2
    1 Publications Verification

    KL-2

    Others Cancer
    SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM .
    SEC inhibitor KL-2
  • HY-X0009

    CDK Others Cancer
    JSH-009 is a novel, highly selective CDK9 inhibitor critical for regulating transcription elongation. JSH-009 demonstrated significant in vitro and in vivo efficacy against acute myeloid leukemia (AML) .
    JSH-009
  • HY-134575

    Apoptosis GSK-3 Others
    C24:1-Ceramide is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain .
    C24:1-Ceramide
  • HY-N6772

    Autophagy Cancer
    Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation .
    Cytochalasin E
  • HY-122464S2

    Isotope-Labeled Compounds Others
    (±)-Jasmonic acid-d5 is the deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
    (±)-Jasmonic acid-d5
  • HY-122464S1

    Isotope-Labeled Compounds Others
    Jasmonic acid-d5 is deuterium labeled (±)-Jasmonic acid. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
    Jasmonic acid-d5
  • HY-P10396

    Bacterial Infection Inflammation/Immunology
    Elf18 is the bacterial N-terminal fragment of Elongation Factor Thermus (EF-Tu). Elf18 is recognized by pattern recognition receptors (PRRs) as a pathogen-associated molecular pattern (PAMP), and thus induces immune response in Arabidopsis .
    Elf18
  • HY-122464B

    2-iso Jasmonic acid; 7-iso Jasmonic acid

    Others Others
    7-epi Jasmonic acid is the isomer of (±)-Jasmonic acid (HY-122464). (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
    7-epi Jasmonic acid
  • HY-100576
    NH125
    1 Publications Verification

    CaMK Autophagy Bacterial Fungal Virus Protease Cancer
    NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII), also can induce eEF2 phosphorylation, with an IC50 of 60 nM for eEF-2K .
    NH125
  • HY-17422B

    HSV Antibiotic Infection Cancer
    Acyclovir monophosphate is a potent anti-herpes simplex virus (HSV) agent. Acyclovir monophosphate blocks DNA synthesis through the inhibition of the viral DNA polymerase and terminates the chain elongation of the viral DNA. Acyclovir monophosphate shows antitumor activity .
    Acyclovir monophosphate
  • HY-122464R

    Others Others
    (±)-Jasmonic acid (Standard) is the analytical standard of (±)-Jasmonic acid. This product is intended for research and analytical applications. (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.
    (±)-Jasmonic acid (Standard)
  • HY-122228

    Others Others
    Cestrin is a cellulose Synthase 1 (CESA1) inhibitor. Cestrin inhibits cell elongation and reduces cellulose content and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CSI1 .
    Cestrin
  • HY-114489A

    Apoptosis Influenza Virus Parasite Infection Neurological Disease Cancer
    Haemanthamine is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities .
    Haemanthamine
  • HY-114489B

    Apoptosis Influenza Virus Parasite Infection Neurological Disease Cancer
    Haemanthamine hydrochloride is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine hydrochloride targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine hydrochloride has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities .
    Haemanthamine hydrochloride
  • HY-145272

    ELOVL Neurological Disease
    ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD) [1].
    ELOVL1-IN-3
  • HY-161771

    RSV Infection
    JNJ-7184 is a non-nucleoside inhibitor of the RSV-Large (L) polymerase, with the pEC50 and pCC50 of 7.86 and 4.29 in Hela cells, respectively. JNJ-7184 prevents RSV replication and transcription by inhibiting initiation or early elongation .
    JNJ-7184
  • HY-114751

    16,16-dimethyl-PGE1

    Others Cardiovascular Disease
    16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation .
    16,16-Dimethylprostaglandin E1
  • HY-125572R

    Others Others
    Gibberellin A7 (Standard) is the analytical standard of Gibberellin A7. This product is intended for research and analytical applications. Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells .
    Gibberellin A7 (Standard)

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