Search Result
Results for "
Fungicidal activity
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W019852
-
|
Fungal
|
Infection
|
Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
|
-
-
- HY-156251
-
|
Fungal
|
Infection
|
Antifungal agent 74 (compound 3c) is a potent antifungal agent that displays excellent fungicidal activity against C. arachidicola and R. solani. Antifungal agent 74 exerts its fungicidal activity by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes .
|
-
-
- HY-151556
-
|
Fungal
|
Infection
|
Antifungal agent 45 is with fungicidal activities. Antifungal agent 45 shows excellent characteristics superior to Kresoxim-methyl (HY-125776), in which the activity enhancement against Phytophthora capsici was the most remarkable, with an EC50 value of about 5 μM .
|
-
-
- HY-114717
-
|
Fungal
|
Infection
|
Pterophyllin 2 is a fungicide against R. stolonifer with a MFC value of 250 μg/mL. Pterophyllin 2 also has antifungal activity against B. cinerea and M. fructicola .
|
-
-
- HY-151555
-
|
Fungal
|
Infection
|
Antifungal agent 44 (compound 2A-5) is an antifungal agent, and shows excellent fungicidal activity superior to Kresoxim-methyl (HY-125776). Antifungal agent 44 shows fungicidal activity against Phytophthora capsici most remarkably, with an EC50 value of about 5 μM .
|
-
-
- HY-169069
-
|
Fungal
|
Infection
|
Antifungal agent 110 exhibits fungicidal activity toward Botrytis cinerea and Rhizoctonia solani. Antifungal agent 110 displays antifungal activity against R. solani with an EC50 value of 0.27 mg/L. Antifungal agent 110 is promising for research of plant diseases .
|
-
-
- HY-155769
-
|
Fungal
|
Infection
|
Antimicrobial agent-24 (compound E8) is a hydrazide compound with excellent and broad-spectrum fungicidal activities. Antimicrobial agent-24 affects the normal function of the plasma membrane, further generating changes in the morphology and subcellular structure of mycelia .
|
-
-
- HY-155658
-
|
Fungal
|
Infection
|
Antifungal agent 62 (Compound 3a) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum f.sp. cucumerinum. Antifungal agent 62 can be used for antiviral and fungicidal research .
|
-
-
- HY-155660
-
|
Fungal
|
Infection
|
Antifungal agent 63 (Compound 3i) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum f.sp. cucumerinum. Antifungal agent 63 can be used for antiviral and fungicidal research .
|
-
-
- HY-155669
-
|
Fungal
|
Infection
|
Antifungal agent 64 (Compound 5c) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum f.sp. cucumerinum. Antifungal agent 64 can be used for antiviral and fungicidal research .
|
-
-
- HY-155670
-
|
Fungal
|
Infection
|
Antifungal agent 65 (Compound 5d) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum f.sp. cucumerinum. Antifungal agent 65 can be used for antiviral and fungicidal research .
|
-
-
- HY-W019852R
-
|
Fungal
|
Infection
|
Flutriafol (Standard) is the analytical standard of Flutriafol. This product is intended for research and analytical applications. Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
|
-
-
- HY-149067
-
|
Fungal
|
Infection
|
Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide .
|
-
-
- HY-N10058
-
|
Fungal
|
Infection
|
Debneyol exhibits more potent fungicidal activity than validamycin.
|
-
-
- HY-123155
-
|
Fungal
|
Infection
|
Pyrimorph is a fungicide with excellent antifungal activity against oomycetes .
|
-
-
- HY-132933
-
|
Fungal
|
Infection
|
Fungicide4 shows the high activity against the P. infestans strain.
|
-
-
- HY-N3056
-
-
-
- HY-N10057
-
|
Fungal
|
Infection
|
5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.
|
-
-
- HY-B2058
-
|
Fungal
|
Infection
|
Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-118547
-
2-Benzyl-4-chlorophenol
|
Bacterial
|
Infection
|
Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide fungicide widely used in hospitals and homes as a broad-spectrum fungicide in general cleaning and disinfection disinfectant solutions and in soap formulations. Clorofene has antibacterial and carcinogenic activity .
|
-
-
- HY-163688
-
|
Antibiotic
Fungal
|
Infection
|
Quindecamine acetate is a derivative of Quinaldine. Quindecamine acetate has antifungal activity .
|
-
-
- HY-B0846
-
|
Fungal
Androgen Receptor
Parasite
|
Infection
|
Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM .
|
-
-
- HY-163634
-
|
Fungal
|
Infection
|
YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity .
|
-
-
- HY-139839
-
|
Fungal
|
Infection
|
Y12196 is a novel succinate dehydrogenase inhibitor (SDHI) which exhibits strong fungicidal activity against F. graminearum.
|
-
-
- HY-133216
-
|
Fungal
|
Infection
|
Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops .
|
-
-
- HY-17522
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2,4-DNOPC
|
Bacterial
|
Infection
|
Meptyldinocap (2,4-DNOPC) is a novel powdery mildew (Erysiphe necator) fungicide which shows protectant and post-infective activities.
|
-
-
- HY-B1133
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Dibenzthione
|
Fungal
|
Infection
|
Sulbentine (Dibenzthione) is an azole antifungal agent that has fungistatic and fungicidal activities. Sulbentine is used as a locally acting antimycotic in vivo .
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-
-
- HY-165611
-
|
Others
|
Others
|
(+)-Lupinine is an alkaloid derived from leguminous plants (such as those of the Lupinus genus) and can be used to synthesize glycyrrhetinamide salts with fungicidal activity .
|
-
-
- HY-B0364AS
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Dyclocaine-d9 hydrochloride
|
Isotope-Labeled Compounds
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
Dyclonine-d9 (hydrochloride) is deuterium labeled Dyclonine (hydrochloride). Dyclonine hydrochloride (Dyclocaine hydrochloride) is an effective component of Runhou tablets. Dyclonine hydrochloride has significant bactericidal and fungicidal activity[1][2].
|
-
-
- HY-136384
-
|
Fungal
|
Infection
|
Diethofencarb is a fungicide with strong activity against Botrytis cinerea and Benzimidazole-resistant strains of Botryis spp. Diethofencarb has a role as an antifungal agrochemical .
|
-
-
- HY-Y0055
-
-
-
- HY-155096
-
|
Bacterial
|
Infection
|
Antibacterial agent 149 (Compd 3j) is a laccase inhibitor with high fungicidal activity and can be used in the study of rice sheath blight .
|
-
-
- HY-B2056
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CELA W 524
|
Fungal
|
Infection
Inflammation/Immunology
|
Triforine (CELA W 524), a systemic fungicide, was shown to display a moderate to distinct fungitoxic activity in vitro towards several pathogenic and non-pathogenic fungi .
|
-
-
- HY-N7144A
-
|
Apoptosis
|
Infection
Cancer
|
Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .
|
-
-
- HY-B0846S
-
|
Fungal
Androgen Receptor
Parasite
|
Infection
|
Dimethomorph-d8 is the deuterium labeled Dimethomorph[1]. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM[2][3][4].
|
-
-
- HY-B0846R
-
|
Fungal
Androgen Receptor
Parasite
|
Infection
|
Dimethomorph (Standard) is the analytical standard of Dimethomorph. This product is intended for research and analytical applications. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM .
|
-
-
- HY-P10160
-
chCATH-2
|
Bacterial
|
Infection
|
Cathelicidin-2 chicken is antimicrobial peptide. Cathelicidin-2 chicken shows potent bactericidal and fungicidal activity against chicken-specific salmonella isolates .
|
-
-
- HY-114509
-
|
Bacterial
|
Infection
Metabolic Disease
|
Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
|
-
-
- HY-B0263
-
-
-
- HY-B2012
-
DPX-H6573
|
Fungal
|
Infection
|
Flusilazole (DPX-H6573), an organosilane fungicide, has broad-spectrum antifungal effect. Flusilazole exhibits curative and preventative activities and is recommended for use in agriculture and horticulture .
|
-
-
- HY-B2058R
-
|
Fungal
|
Infection
|
Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities .
|
-
-
- HY-163297
-
|
Fungal
|
Infection
|
Antifungal agent 90 (Compound 7n) is an antifungal agent that inhibits ergosterol biosynthesis. Antifungal agent 90 showed excellent antifungal activity against Valsa mali and Botrytis cinerea with EC50 values respectively. 4.26 and 1.41 μg/mL .
|
-
-
- HY-156270
-
|
Bacterial
|
Infection
|
SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC50 of 0.93 μg/mL .
|
-
-
- HY-N3056R
-
|
Bacterial
Fungal
|
Infection
|
Pinosylvin monomethyl ether (Standard) is the analytical standard of Pinosylvin monomethyl ether. This product is intended for research and analytical applications. Pinosylvin monomethyl ether has antibacterial effect and fungicidal activity .
|
-
-
- HY-W040156
-
|
Others
|
Infection
|
Oxadixyl is a fungicide with activity that inhibits the growth of fungi. Oxadixyl was tested during the malic fermentation of red wine, where its concentration may be affected. The biological activity of Oxadixyl helps to evaluate its effect on microorganisms during the winemaking process .
|
-
-
- HY-W017401
-
BIT
|
Others
|
Infection
Cancer
|
Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .
|
-
-
- HY-Y0055S
-
|
Antibiotic
Fungal
Bacterial
|
Infection
Neurological Disease
|
Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
|
-
-
- HY-135761
-
|
Fungal
Cholinesterase (ChE)
|
Infection
Neurological Disease
|
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats .
|
-
-
- HY-133216R
-
|
Fungal
|
Infection
|
Bupirimate (Standard) is the analytical standard of Bupirimate. This product is intended for research and analytical applications. Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops .
|
-
-
- HY-156281
-
|
Fungal
|
Infection
|
Antifungal agent 76 (compound 23h) exhibits potent activities and a broad antifungal spectrum with low MICs of 0.25-16 μg/mL. Antifungal agent 76 might achieve its rapid fungicidal activity by disrupting the fungal cell membrane .
|
-
- HY-17520
-
MTF-753
|
Fungal
|
Infection
|
Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
|
-
- HY-A0278
-
(-)-Hexaconazol
|
Fungal
Reactive Oxygen Species
SOD
|
Infection
Endocrinology
|
Hexaconazole is a demethylation enzyme inhibitor and a synthetic fungicide that targets many fungi, especially ascomycetes and basidiomycetes, and it can enhance the activity of SOD and peroxidase. Hexaconazole causes endocrine disorders in zebrafish larvae .
|
-
- HY-123230
-
CGA 279202
|
Fungal
Caspase
PARP
Apoptosis
|
Infection
Neurological Disease
|
Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .
|
-
- HY-135307
-
Huanjunzuo
|
Fungal
|
Infection
|
SSF-109 is a broad-spectrum fungicide which has protective activity against plant disease. SSF-109 inhibits the biosynthesis of ergosterol at the 14α-demethylation step in Botrytis cinerea .
|
-
- HY-162784
-
|
Fungal
Cytochrome P450
|
Infection
|
CYP51-IN-19 (compound C07) is a potent CYP51 inhibitor. CYP51-IN-19 stimulates reactive oxygen species (ROS) and exhibits potent fungicidal activity .
|
-
- HY-Y0055R
-
|
Antibiotic
Fungal
Bacterial
Parasite
|
Infection
Neurological Disease
|
Phenothiazine (Standard) is the analytical standard of Phenothiazine. This product is intended for research and analytical applications. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases .
|
-
- HY-136384R
-
|
Fungal
|
Infection
|
Diethofencarb (Standard) is the analytical standard of Diethofencarb. This product is intended for research and analytical applications. Diethofencarb is a fungicide with strong activity against Botrytis cinerea and Benzimidazole-resistant strains of Botryis spp. Diethofencarb has a role as an antifungal agrochemical .
|
-
- HY-B0348
-
Piritetrate; M-732
|
Fungal
|
Infection
|
Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
|
-
- HY-N7144AR
-
|
Apoptosis
|
Infection
Cancer
|
Citronellyl acetate (Standard) is the analytical standard of Citronellyl acetate. This product is intended for research and analytical applications. Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .
|
-
- HY-B2056R
-
|
Fungal
|
Infection
Inflammation/Immunology
|
Triforine (Standard) is the analytical standard of Triforine. This product is intended for research and analytical applications. Triforine (CELA W 524), a systemic fungicide, was shown to display a moderate to distinct fungitoxic activity in vitro towards several pathogenic and non-pathogenic fungi .
|
-
- HY-163462
-
|
Fungal
|
Infection
|
Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants .
|
-
- HY-W127739
-
Zinc ethylene-1, 2-bisdithiocarbamate
|
Biochemical Assay Reagents
|
Others
|
Zineb is an agricultural fungicide of the dithiocarbamate class. Its toxicity is relatively low, and there is little evidence of human harm from exposure. Oxidative stress is one of the main factors contributing to diseases caused by Zineb. Zineb does not alter the activity of any superoxide dismutase enzymes. Catalase (CAT) activity was reduced only by Zineb.
|
-
- HY-163571
-
|
Fungal
Cytochrome P450
Bacterial
|
Infection
|
CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. CYP51-IN-17 shows significant fungicidal activity against B. cinerea with an EC50 of 0.326 μg/mL .
|
-
- HY-163633
-
|
Cytochrome P450
Fungal
Bacterial
|
Infection
|
CYP51-IN-18 (compound 2l) is a potent CYP51 inhibitor with an IC50 of 0.219 μg/mL. CYP51-IN-18 shows significant fungicidal activity against B. cinerea with an EC50 of 0.369 μg/mL .
|
-
- HY-B2012R
-
|
Fungal
|
Infection
|
Flusilazole (Standard) is the analytical standard of Flusilazole. This product is intended for research and analytical applications. Flusilazole (DPX-H6573), an organosilane fungicide, has broad-spectrum antifungal effect. Flusilazole exhibits curative and preventative activities and is recommended for use in agriculture and horticulture .
|
-
- HY-P0027
-
|
Arp2/3 Complex
Fungal
|
Infection
Cancer
|
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
|
-
- HY-116992
-
Demosan; TERSAN SP(R)
|
Others
|
Infection
|
Chloroneb (Demosan) is a pesticide with fungicidal and plant-protective activities. Chloroneb can be used to detect organochlorine pesticide residues, showing good selectivity, stability and reproducibility. Chloroneb has been applied to the detection of licorice, cucumber, river water and soil samples with satisfactory results .
|
-
- HY-117451
-
|
Others
|
Infection
|
Dodine is a fungicide with plant disease suppressive activity. Dodine is used to control black spot on apples, pears and pecans, brown rot on peaches, and a variety of foliar diseases of peaches, strawberries, cherries, jacaranda and black walnuts. Dodine is also used as an industrial biocide and preservative .
|
-
- HY-W017401R
-
|
Others
|
Infection
Cancer
|
Benzisothiazolone (Standard) is the analytical standard of Benzisothiazolone. This product is intended for research and analytical applications. Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .
|
-
- HY-B0567
-
|
Potassium Channel
nAChR
Apoptosis
Bacterial
Parasite
|
Infection
Cancer
|
Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR, and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity .
|
-
- HY-B1134
-
Enilconazole
|
Fungal
|
Infection
|
Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .
|
-
- HY-135761S
-
|
Fungal
Cholinesterase (ChE)
|
Infection
|
Penconazole-d7 is the deuterium labeled Penconazole[1]. Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[2][3].
|
-
- HY-W021040
-
CGA-173506
|
Fungal
Apoptosis
|
Infection
Cancer
|
Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells .
|
-
- HY-135761R
-
|
Fungal
Cholinesterase (ChE)
|
Infection
Neurological Disease
|
Penconazole (Standard) is the analytical standard of Penconazole. This product is intended for research and analytical applications. Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats .
|
-
- HY-13582
-
|
Fungal
Parasite
|
Infection
Cancer
|
Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina . Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .
|
-
- HY-123230R
-
CGA 279202 (Standard)
|
Fungal
Caspase
PARP
Apoptosis
|
Infection
Neurological Disease
|
Trifloxystrobin (Standard) is the analytical standard of Trifloxystrobin. This product is intended for research and analytical applications. Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .
|
-
- HY-17520R
-
|
Fungal
|
Infection
|
Penthiopyrad (Standard) is the analytical standard of Penthiopyrad. This product is intended for research and analytical applications. Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
|
-
- HY-13582A
-
|
Fungal
Parasite
|
Infection
Cancer
|
Carbendazim hydrochloride is a potent and orally active broad-spectrum?benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria,?Fusarium?and?Sclerotina . Carbendazim hydrochloride is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .
|
-
- HY-122950
-
|
Fungal
|
Infection
|
Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide .
|
-
- HY-N6625
-
|
Fungal
Estrogen Receptor/ERR
|
Infection
|
Chlorothalonil is a broad-spectrum foliar fungicide with oral activity. Chlorothalonil can be used to combat fungal diseases in vegetable and crop leaves. Chlorothalonil can alter the microbial community in the soil. Chlorothalonil inhibits spermatogenesis. Chlorothalonil can cause intestinal epithelial barrier dysfunction and fetal toxicity .
|
-
- HY-B0348R
-
|
Fungal
|
Infection
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Liranaftate (Standard) is the analytical standard of Liranaftate. This product is intended for research and analytical applications. Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
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- HY-B0856
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Fungal
Tyrosinase
Antibiotic
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Infection
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Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
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- HY-B1134A
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Enilconazolel sulfate
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Fungal
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Infection
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Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .
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- HY-124894
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Fungal
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Infection
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(+)-Benalaxyl is a broad-spectrum benzamide fungicide. (+)-Benalaxyl inhibits the growth of the freshwater algae S. obliquus, with an EC50 value of 8.441 mg/L. (+)-Benalaxyl can induce the production of chlorophyll a and b, as well as increase the activity of superoxide dismutase (SOD) and the generation of malondialdehyde (MDA). (+)-Benalaxyl has inhibitory effects on catalase (CAT). (+)-Benalaxyl is effective against diseases caused by oomycetes .
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- HY-130406
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Others
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Infection
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Benthiavalicarb isopropyl is a fungicide with specific activity against downy mildew and blight. Benthiavalicarb isopropyl is evaluated for use where necessary to control a serious threat to plant health that cannot be treated by other methods, including non-chemical methods. The use of Benthiavalicarb isopropyl can be considered representative of field applications in potatoes. Environmental and human exposures of Benthiavalicarb isopropyl are considered to be negligible .
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- HY-13582S
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Isotope-Labeled Compounds
Fungal
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Infection
Cancer
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Carbendazim-d4 is the deuterium labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma[3].
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- HY-B0567R
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Potassium Channel
nAChR
Apoptosis
Bacterial
Parasite
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Infection
Cancer
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Dequalinium (Chloride) (Standard) is the analytical standard of Dequalinium (Chloride). This product is intended for research and analytical applications. Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR, and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity .
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- HY-13582R
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Parasite
Fungal
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Infection
Cancer
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Carbendazim (Standard) is the analytical standard of Carbendazim. This product is intended for research and analytical applications. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina . Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .
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- HY-B1134R
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Fungal
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Infection
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Imazalil (Standard) is the analytical standard of Imazalil. This product is intended for research and analytical applications. Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .
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- HY-N6625R
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Fungal
Estrogen Receptor/ERR
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Infection
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Chlorothalonil (Standard) is the analytical standard of Chlorothalonil. This product is intended for research and analytical applications. Chlorothalonil is a broad-spectrum foliar fungicide with oral activity. Chlorothalonil can be used to combat fungal diseases in vegetable and crop leaves. Chlorothalonil can alter the microbial community in the soil. Chlorothalonil inhibits spermatogenesis. Chlorothalonil can cause intestinal epithelial barrier dysfunction and fetal toxicity .
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- HY-161010
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Dihydrofolate reductase (DHFR)
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Infection
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DHFR-IN-13 (Compd Hit8) is an active R. solani DHFR inhibitor with an IC50 value of 10.2 μM. DHFR-IN-13 has selectivity of inhibition against human DHFR with an IC50 value of 227.7 μM. DHFR-IN-13 also is a fungicide. DHFR-IN-13 has high antifungal activity against R. solani with EC50 value of 38.2 mg/L .
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- HY-161856
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mTOR
Fungal
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Others
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Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits .
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- HY-B0856R
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Fungal
Tyrosinase
Antibiotic
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Infection
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Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .
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- HY-150686
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Fungal
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Infection
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Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential chitin synthase-based fungicide in agriculture .
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Cat. No. |
Product Name |
Type |
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- HY-W127739
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Zinc ethylene-1, 2-bisdithiocarbamate
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Biochemical Assay Reagents
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Zineb is an agricultural fungicide of the dithiocarbamate class. Its toxicity is relatively low, and there is little evidence of human harm from exposure. Oxidative stress is one of the main factors contributing to diseases caused by Zineb. Zineb does not alter the activity of any superoxide dismutase enzymes. Catalase (CAT) activity was reduced only by Zineb.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P0027
-
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Arp2/3 Complex
Fungal
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Infection
Cancer
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Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
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- HY-P10160
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chCATH-2
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Bacterial
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Infection
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Cathelicidin-2 chicken is antimicrobial peptide. Cathelicidin-2 chicken shows potent bactericidal and fungicidal activity against chicken-specific salmonella isolates .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-Y0055S
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Phenothiazine-d8 is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].
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- HY-135761S
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Penconazole-d7 is the deuterium labeled Penconazole[1]. Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[2][3].
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- HY-B0364AS
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Dyclonine-d9 (hydrochloride) is deuterium labeled Dyclonine (hydrochloride). Dyclonine hydrochloride (Dyclocaine hydrochloride) is an effective component of Runhou tablets. Dyclonine hydrochloride has significant bactericidal and fungicidal activity[1][2].
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- HY-B0846S
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Dimethomorph-d8 is the deuterium labeled Dimethomorph[1]. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 μM[2][3][4].
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-
- HY-13582S
-
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Carbendazim-d4 is the deuterium labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma[3].
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