Search Result
Results for "
PEG6
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-122702
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PROTAC Linkers
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Others
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PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation .
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- HY-130408
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130410
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ADC Linker
PROTAC Linkers
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Cancer
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Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-156691A
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Drug-Linker Conjugates for ADC
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Cancer
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TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride is a Drug-Linker Conjugates for ADC. TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride is the hydrochloride form of TLR7/8 agonist 4 hydroxy-PEG6-acid. TLR7/8 agonist 4 hydroxy-PEG6-acid consists of TLR7/8 agonist 4 (HY-139017) and a linker Hydroxy-PEG6-acid (HY-133050), and can be used for synthesis of ADCs .
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- HY-130486
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PROTAC Linkers
ADC Linker
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Cancer
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NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-163209
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(S,R,S)-AHPC-PEG6-NH2 hydrochloride
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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VH 032 amide-PEG6-amine hydrochloride (Step 4) is a functionalized von-Hippel-Lindau protein-ligand (VHL) for PROTAC development, consisting of an E3 ligand and a PEG6 ligand. Terminal amines can be coupled to target protein ligands .
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- HY-140121
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ADC Linker
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Cancer
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m-PEG6-SS-PEG6-methyl is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130386
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-117186
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PROTAC Linkers
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Metabolic Disease
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Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130385
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141034
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PROTAC Linkers
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Cancer
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Cy5-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-139292
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Amino Acid Derivatives
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Cancer
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Fmoc-NH-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-alcohol is extracted from patent WO2016030791, example comp 91 .
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- HY-155256
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Ligands for E3 Ligase
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Cancer
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Thalidomide-5-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
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- HY-126942
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133066
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PROTAC Linkers
ADC Linker
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Inflammation/Immunology
Cancer
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m-PEG6-NHS ester is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-126918
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PROTAC Linkers
ADC Linker
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Cancer
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THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W042654
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- HY-126963
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PROTAC Linkers
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Cancer
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Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-133176
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PROTAC Linkers
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Cancer
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Biotin-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
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- HY-W071584
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ADC Linker
PROTAC Linkers
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Cancer
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N-Boc-PEG6-alcohol is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG6-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130580
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HS-PEG6-OH
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PROTAC Linkers
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Cancer
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Thiol-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-120587
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PROTAC Linkers
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Cancer
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Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141160
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PROTAC Linkers
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Cancer
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TCO-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-140495
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PROTAC Linkers
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Cancer
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DNP-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133291
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PROTAC Linkers
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Cancer
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Thiol-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133050
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PROTAC Linkers
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Cancer
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Hydroxy-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138393
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138411
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PROTAC Linkers
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Cancer
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Cl-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138505
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PROTAC Linkers
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Cancer
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Iodoacetamido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141044
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PROTAC Linkers
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Cancer
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Cy5-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130382
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PROTAC Linkers
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Cancer
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Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130384
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PROTAC Linkers
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Cancer
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Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140284
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PROTAC Linkers
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Cancer
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DBCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-135917
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PROTAC Linkers
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Cancer
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Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-138321
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PROTAC Linkers
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Cancer
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Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140616
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DNP-PEG6-t-butyl ester
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PROTAC Linkers
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Cancer
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DNP-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133468
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-140994
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PROTAC Linkers
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Cancer
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Bis-Mal-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140367
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PROTAC Linkers
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Cancer
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Bis-Tos-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096147
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PROTAC Linkers
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Cancer
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S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096166
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PROTAC Linkers
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Cancer
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Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138709
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-156691
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Drug-Linker Conjugates for ADC
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Cancer
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TLR7/8 agonist 4 hydroxy-PEG6-acid is a Drug-Linker Conjugates for ADC. TLR7/8 agonist 4 hydroxy-PEG6-acid consists of TLR7/8 agonist 4 (HY-139017) and a linker Hydroxy-PEG6-acid (HY-133050), and can be used for synthesis of ADCs .
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- HY-140881
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PROTAC Linkers
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Cancer
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Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140075
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PROTAC Linkers
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Cancer
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endo-BCN-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG6-Boc is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-135958
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG6-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-133367
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-133373
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PROTAC Linkers
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Cancer
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DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140284A
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PROTAC Linkers
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Others
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DBCO-PEG6-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG6-amine (TFA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-156172
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Ligands for E3 Ligase
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Cancer
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Thalidomide-NH-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
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- HY-135049
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PROTAC Linkers
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Cancer
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Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-130336
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PROTAC Linkers
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Cancer
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m-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130399
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PROTAC Linkers
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Cancer
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Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141168
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PROTAC Linkers
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Cancer
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TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141180
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PROTAC Linkers
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Cancer
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TCO-PEG6-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141376
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PROTAC Linkers
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Cancer
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m-PEG6-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-133061
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PROTAC Linkers
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Cancer
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Fluorescein-thiourea-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126882
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PROTAC Linkers
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Cancer
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Fmoc-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140942
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- HY-141083
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PROTAC Linkers
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Cancer
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Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130496
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PROTAC Linkers
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Cancer
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Ald-Ph-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130454
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PROTAC Linkers
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Cancer
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Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133211
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PROTAC Linkers
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Cancer
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Mal-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-126717
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PROTAC Linkers
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Cancer
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SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140364
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PROTAC Linkers
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Cancer
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m-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141215
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PROTAC Linkers
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Cancer
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Bromo-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141367
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PROTAC Linkers
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Cancer
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Bromo-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141329
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PROTAC Linkers
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Cancer
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m-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140897
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PROTAC Linkers
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Cancer
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Biotin-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140240
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- HY-140936
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PROTAC Linkers
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Cancer
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Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140890
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PROTAC Linkers
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Cancer
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Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140356
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PROTAC Linkers
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Cancer
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Tos-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-135922
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PROTAC Linkers
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Cancer
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m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130891
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PROTAC Linkers
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Cancer
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(+)-Biotin-PEG6-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133353
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PROTAC Linkers
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Cancer
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Mal-PEG6-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132026
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132028
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132029
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132030
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-134711
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PROTAC Linkers
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Cancer
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Amine-PEG6-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138315
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PROTAC Linkers
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Cancer
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Ms-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138324
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PROTAC Linkers
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Cancer
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Ms-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138395
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PROTAC Linkers
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Cancer
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DSPE-PEG6-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138419
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PROTAC Linkers
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Cancer
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Biotin-PEG6-Silane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138449
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PROTAC Linkers
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Cancer
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m-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W096156
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PROTAC Linkers
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Cancer
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I-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132105
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PROTAC Linkers
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Cancer
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Benzyl-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W190960
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PROTAC Linkers
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Cancer
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Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-134711A
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PROTAC Linkers
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Cancer
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Amine-PEG6-thiol hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-136086
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ADC Linker
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Cancer
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Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG6-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-130180
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PROTAC Linkers
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Cancer
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Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-23105
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PROTAC Linkers
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Cancer
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Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.
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- HY-130474
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ADC Linker
PROTAC Linkers
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Cancer
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130537
-
|
PROTAC Linkers
ADC Linker
|
Cancer
|
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140215
-
|
PROTAC Linkers
ADC Linker
|
Cancer
|
Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130085
-
|
ADC Linker
|
Cancer
|
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
|
-
- HY-140893
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140908
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130885
-
|
PROTAC Linkers
|
Cancer
|
N3-PEG6-Propanehydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG6-Propanehydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140054
-
|
PROTAC Linkers
|
Cancer
|
t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-aminooxy-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130364
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG6-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130548
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-2-methylacrylate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-W008879
-
|
PROTAC Linkers
|
Cancer
|
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141348
-
|
PROTAC Linkers
|
Cancer
|
S-acetyl-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130141
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140486
-
|
PROTAC Linkers
|
Cancer
|
Acid-PEG6-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140231
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141084
-
|
PROTAC Linkers
|
Cancer
|
Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140627
-
|
PROTAC Linkers
|
Cancer
|
Ald-Ph-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133473
-
|
PROTAC Linkers
|
Cancer
|
S-acetyl-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132034
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096076
-
|
PROTAC Linkers
|
Cancer
|
Bis-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190945
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140453
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-135918
-
|
PROTAC Linkers
|
Cancer
|
NH2-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-129311
-
-
- HY-140115
-
|
ADC Linker
|
Cancer
|
Bis-(PEG6-acid)-SS is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-132086
-
|
ADC Linker
|
Cancer
|
2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-156171
-
|
Ligands for E3 Ligase
|
Cancer
|
Thalidomide-5-NH-PEG6-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-5-NH-PEG6-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs .
|
-
- HY-138362
-
|
PROTAC Linkers
|
Cancer
|
Br-PEG6-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138331
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-N-amido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040257
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140353
-
|
PROTAC Linkers
|
Cancer
|
Azide-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140772
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140823
-
|
PROTAC Linkers
|
Cancer
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133393
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138325
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138363
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W096070
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133461
-
|
PROTAC Linkers
|
Cancer
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140188
-
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic acid
|
PROTAC Linkers
|
Cancer
|
Amino-PEG6-amido-C16-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-115374
-
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140911
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-160773
-
|
Biochemical Assay Reagents
|
Others
|
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W035376
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-CH2CH2CHO is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
|
-
- HY-130526
-
|
PROTAC Linkers
|
Cancer
|
Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133071
-
|
PROTAC Linkers
|
Cancer
|
Tos-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140482
-
|
PROTAC Linkers
|
Cancer
|
Acid-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130443
-
|
PROTAC Linkers
|
Cancer
|
Cbz-NH-PEG6-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141211
-
|
PROTAC Linkers
|
Cancer
|
Hydroxy-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133341
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133302
-
|
PROTAC Linkers
|
Cancer
|
HO-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134691
-
|
PROTAC Linkers
|
Cancer
|
Propanol-PEG6-CH2OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138349
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138381
-
|
PROTAC Linkers
|
Cancer
|
Br-PEG6-C2-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190969
-
|
PROTAC Linkers
|
Cancer
|
Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096165
-
|
PROTAC Linkers
|
Cancer
|
t-Boc-N-amido-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140201
-
17-(Amino-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140838
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130183
-
|
PROTAC Linkers
|
Cancer
|
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W040244
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140779
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140477
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141310
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141315
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-C6-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140506
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-O-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-139332
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .
|
-
- HY-140796
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134696
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141009
-
|
PROTAC Linkers
|
Cancer
|
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Mal-PEG6)-N-bis(PEG7-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140787
-
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
PROTAC Linkers
|
Cancer
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-103606
-
VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
(S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays .
|
-
- HY-164706
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
m-PEG6-Lys-Mal-Toxophore-quinoline is a drug-linker conjugate for ADC and can be used for ADC synthesis. The payload is a NAMPT inhibitor (HY-164760) .
|
-
- HY-W040239
-
|
PROTAC Linkers
|
Cancer
|
m-PEG6-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130881
-
|
PROTAC Linkers
|
Cancer
|
HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096106
-
|
PROTAC Linkers
|
Cancer
|
CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140248
-
|
PROTAC Linkers
|
Cancer
|
N-(Mal-PEG6)-N-bis(PEG3-amine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136156
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology .
|
-
- HY-136161
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.
|
-
- HY-130862
-
|
PROTAC Linkers
|
Cancer
|
Mal-NH-PEG6-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040246
-
-
- HY-130957
-
|
ADC Linker
|
Cancer
|
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-161250
-
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PROTACs
|
Cancer
|
Pomalidomide-NH-PEG6-amide-C2-CPI-1612 (compound 22 (dCE-1)) is a CBP/EP300 degrader, which contains a CRBN ligands Pomalidomide, a 24-atom linker with 6 PEG units and a HAT inhibitor CPI-1612. Pomalidomide-NH-PEG6-amide-C2-CPI-1612 exhibits antiproliferative effects in cells multiple myeloma cells LP1 (with a DC50 of 1.2 μM), MM1S and various cancer cell lines, especially the leukemia cells .
|
-
- HY-141202
-
|
PROTAC Linkers
|
Cancer
|
Hydroxy-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126892
-
|
PROTAC Linkers
ADC Linker
|
Cancer
|
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140822
-
|
PROTAC Linkers
|
Cancer
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-P10563
-
BHV-1100
|
CD38
|
Cancer
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
-
- HY-141203
-
|
PROTAC Linkers
|
Cancer
|
Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10563
-
BHV-1100
|
CD38
|
Cancer
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
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Cat. No. |
Product Name |
|
Classification |
-
- HY-130382
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130386
-
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
Propargyl-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-117186
-
|
|
Alkynes
PROTAC Synthesis
|
Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates . Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130385
-
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141160
-
|
|
TCO
|
TCO-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-130384
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140284
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135917
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-138321
-
|
|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133468
-
|
|
Tetrazine
PROTAC Synthesis
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140881
-
|
|
PROTAC Synthesis
Alkynes
|
Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140075
-
|
|
PROTAC Synthesis
BCN
|
endo-BCN-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG6-Boc is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-135958
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-NHCO-PEG6-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133367
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-NHCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133373
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140284A
-
|
|
DBCO
PROTAC Synthesis
|
DBCO-PEG6-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG6-amine (TFA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141168
-
|
|
TCO
|
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141180
-
|
|
TCO
|
TCO-PEG6-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-136086
-
|
|
ADC Synthesis
Tetrazine
|
Tetrazine-PEG6-amine (hydrochloride) is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG6-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130180
-
|
|
Alkynes
PROTAC Synthesis
|
Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130474
-
|
|
Azide
ADC Synthesis
PROTAC Synthesis
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130537
-
|
|
Azide
ADC Synthesis
PROTAC Synthesis
|
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140215
-
|
|
PROTAC Synthesis
ADC Synthesis
Azide
|
Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130885
-
|
|
Azide
PROTAC Synthesis
|
N3-PEG6-Propanehydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N3-PEG6-Propanehydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140054
-
|
|
PROTAC Synthesis
Alkynes
|
t-Boc-aminooxy-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . t-Boc-aminooxy-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140453
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140353
-
|
|
PROTAC Synthesis
Azide
|
Azide-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140772
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140823
-
|
|
Azide
PROTAC Synthesis
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133393
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138325
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138363
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W096070
-
|
|
PROTAC Synthesis
Azide
|
Benzyl-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133461
-
|
|
Tetrazine
PROTAC Synthesis
|
Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-PEG6-NH-Boc is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-115374
-
|
|
Azide
ADC Synthesis
|
m-PEG6-azide is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140911
-
|
|
PROTAC Synthesis
Azide
|
Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-160773
-
|
|
DBCO
|
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-140838
-
|
|
Azide
PROTAC Synthesis
|
Boc-NH-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130183
-
|
|
Alkynes
PROTAC Synthesis
Azide
|
Propargyl-PEG6-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140779
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-139332
-
|
|
Azide
|
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .
|
-
- HY-140796
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-134696
-
|
|
PROTAC Synthesis
Azide
|
Azido-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141009
-
|
|
PROTAC Synthesis
TCO
|
N-(Mal-PEG6)-N-bis(PEG7-TCO) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Mal-PEG6)-N-bis(PEG7-TCO) is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-140787
-
17-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester
|
|
Azide
PROTAC Synthesis
|
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG6-amido-C16-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130957
-
|
|
ADC Synthesis
Azide
|
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140822
-
|
|
PROTAC Synthesis
Azide
|
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
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