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Results for "

Tripeptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) ADC Cytotoxin (3) Amino Acid Derivatives (8) Amyloid-β (1) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (1) Apoptosis (6) Bacterial (3) Beta-secretase (1) Biochemical Assay Reagents (2) Cathepsin (3) Dipeptidyl Peptidase (1) Elastase (1) Endogenous Metabolite (2) FAP (1) Fungal (2) Glutathione Peroxidase (1) Glutathione S-transferase (2) GnRH Receptor (1) HIV (1) HSV (2) Integrin (3) Microtubule/Tubulin (3) Neurokinin Receptor (2) NF-κB (1) Proteasome (1) Reactive Oxygen Species (1) SARS-CoV (2) Toll-like Receptor (TLR) (1) Tyrosinase (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (6) Endocrinology (2) Infection (10) Inflammation/Immunology (7) Metabolic Disease (6) Neurological Disease (10)

By Targets:

ADC Antibody (1)

ADC Cytotoxin (3)

Amino Acid Derivatives (8)

Amyloid-β (1)

Angiotensin-converting Enzyme (ACE) (3)

Antibiotic (1)

Apoptosis (6)

Bacterial (3)

Beta-secretase (1)

Biochemical Assay Reagents (2)

Cathepsin (3)

Dipeptidyl Peptidase (1)

Elastase (1)

Endogenous Metabolite (2)

FAP (1)

Fungal (2)

Glutathione Peroxidase (1)

Glutathione S-transferase (2)

GnRH Receptor (1)

HIV (1)

HSV (2)

Integrin (3)

Microtubule/Tubulin (3)

Neurokinin Receptor (2)

NF-κB (1)

Proteasome (1)

Reactive Oxygen Species (1)

SARS-CoV (2)

Toll-like Receptor (TLR) (1)

Tyrosinase (1)

By Research Areas:

Cancer (18)

Cardiovascular Disease (6)

Endocrinology (2)

Infection (10)

Inflammation/Immunology (7)

Metabolic Disease (6)

Neurological Disease (10)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB	Metabolic Disease
Tripeptide-41(CG-Lipoxyn)isa bioactive peptide withreduce fat accumulationeffect and has been reported used as a cosmetic ingredient .

HY-P0063

Copper tripeptide 1 Publications Verification GHK-Cu	Endogenous Metabolite	Inflammation/Immunology
Copper tripeptide (GHK-Cu) is a *tripeptide. During wound healing, copper tripeptide* may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .

HY-114424A

H-Ile-Pro-Pro-OH hydrochloride 1 Publications Verification	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide , inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM . Antihypertensive tripeptides .

HY-103323

Fas C-Terminal Tripeptide	FAP	Others
Fas C-Terminal Tripeptide is a C-terminal tripeptide of Fas. Fas C-Terminal Tripeptide shows the inhibitory effect on Fas/FAP-1 binding .

HY-P0104

*Palmitoyl tripeptide-38*	Reactive Oxygen Species	Metabolic Disease
Palmitoyl tripeptide-38 is a bioactive peptide with anti-aging effect .

HY-P5252

*Diaminopropionoyl tripeptide-33*	Tyrosinase	Metabolic Disease
Diaminopropionoyl tripeptide-33isa bioactive peptide with protects skin cells from UVA-induced DNA damages and has been reported used as a cosmetic ingredient .

HY-66018

*Palmitoyl tripeptide-5 biTFA*	Others	Others
Palmitoyl tripeptide-5 biTFA is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-114424

H-Ile-Pro-Pro-OH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
H-Ile-Pro-Pro-OH, a milk-derived peptide , inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM . Antihypertensive tripeptides .

HY-P10208

RKH	Toll-like Receptor (TLR)	Infection
PKH is a TLR4 antagonist. PKH is a novel tripeptide and can be isolated from Akkermansia muciniphila. RKH reduces sepsis-induced inflammatory cell activation and proinflammatory factor overproduction .

HY-P3424

NH2-AKK-COOH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC₅₀s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively .

HY-W016012

Glu-Glu	Amino Acid Derivatives	Others
Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption .

HY-136736

β-Secretase Inhibitor II	Beta-secretase	Neurological Disease
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC₅₀=700 nM for inhibition of total Aβ and IC₅₀=2.5 μM for Aβ_1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease .

HY-13634

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

HY-13634A

Ezatiostat Maximum Cited Publications 7 Publications Verification TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

HY-122487

Troriluzole BHV-4157	Others	Neurological Disease
Troriluzole, a third-generation, tripeptide proagent of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD) .

HY-123587

PR-924	Proteasome Apoptosis	Cancer
PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC₅₀ of 22 nM. PR-924 covalently modifies proteasomal N-terminal threonine active sites. PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities .

HY-123587A

(R)-PR-924	Others	Cancer
(R)-PR-924 is the isomer of PR-924 (HY-123587), and can be used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC₅₀ of 22 nM. PR-924 covalently modifies proteasomal N-terminal threonine active sites. PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities .

HY-W010873

Z-Pro-Leu-Gly-OEt	Amino Acid Derivatives	Others
Z-Pro-Leu-Gly-OEt is a tripeptide .

HY-P10118

Cathepsin L-IN-3	Cathepsin	Others
Cathepsin L-IN-3 is a tripeptide-sized cathepsin L inhibitor.

HY-P4362

Suc-Ala-Pro-Ala-AMC	Elastase	Others
Suc-Ala-Pro-Ala-AMC is a tripeptide substrate of elastase .

HY-105436

FR 113680	Neurokinin Receptor	Neurological Disease
FR 113680 is a tripeptide substance P antagonist that interacts selectively with the NK₁ neurokinin receptor .

HY-P0278

RGD 5+ Cited Publications	Integrin	Cancer
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

HY-P0278A

RGD Trifluoroacetate 5+ Cited Publications	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

HY-P4648

H-Trp-Trp-Trp-OH	Bacterial	Infection
H-Trp-Trp-Trp-OH is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity .

HY-P2267

LDV 1 Publications Verification	Integrin	Others
LDV is a non-fluorescent analog of LDV-FITC. LDV is a α4β1 integrin (VLA-4) ligand, and binds α4β1 integrin in leukemia cells .

HY-P3888

Gly-Leu-Met-NH2	Neurokinin Receptor	Neurological Disease
Gly-Leu-Met-NH2 is a C-terminal tripeptide of Substance P (Substance P (HY-P0201)). Substance P is a neuropeptide .

HY-P4287

H-Gly-Lys-Gly-OH	Amino Acid Derivatives	Others
H-Gly-Lys-Gly-OH is a tripeptide containing glycine and lysine. H-Gly-Lys-Gly-OH can be used for the synthesis of casein and soybean protein .

HY-162397

Neopetromin	Others	Others
Neopetromin is a tripeptide with a rare heteroaromatic C-N cross-link between side chains of tryptophan and tyrosine. Neopetromin causes vacuole fragmentation in an actin-independent manner .

HY-148666

H-Gly-Oet	Others	Others
H-Gly-Oet can be coupled with Z-Pro-Leu-OEt for the synthesis of tripeptide Z-Pro-Leu-Gly-OEt by thermolysin and α-chymotrypsin catalysis .

HY-108729

Tripeptidyl aminopeptidase Cerliponase alfa	Endogenous Metabolite	Neurological Disease
Tripeptidyl aminopeptidase (Cerliponase alfa) removes tripeptides from the free NH, terminus of longer peptides. Tripeptidyl aminopeptidase has the potential for the research of CLN2 disease .

HY-122414

Phosalacine	Antibiotic Bacterial Fungal	Infection
Phosalacine is a phosphorouscontaining tripeptide herbicidal antibiotic that can be isolated from soil isolate Kitasatosporia phosalacinea KA-338. Phosalacine also shows antibacterial and antifungal activity .

HY-143686

ImmTher	Biochemical Assay Reagents	Cancer
ImmTher is a liposome-encapsulated lipophilic disaccharide tripeptide derivative of muramyl dipeptide. ImmTher can up-regulate specific monocyte cytokine genes and activate monocyte-mediated tumoricidal activity .

HY-P4294

H-Gly-Pro-Gly-OH	Amino Acid Derivatives	Others
H-Gly-Pro-Gly-OH is a tripeptide containing glycine and proline. H-Gly-Pro-Gly-OH can be used for the synthesis of other polypeptides, such as (Pro Gly Gly)_n .

HY-114707

Threonyl-seryl-lysine	GnRH Receptor	Endocrinology
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .

HY-156560

Z-LVG	Others	Infection
Z-LVG is an irreversible cysteine proteinase inhibitor. Z-LVG is a tripeptide derivative from cystatin C which can inhibit viral replication. Z-LVG can be used for virus diseases research .

HY-122494

Bilanafos SF-1293	Bacterial	Infection
Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases .

HY-111173

Diprotin B	Dipeptidyl Peptidase	Others
Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue .

HY-126946

Nikkomycin pseudo-J	Fungal	Infection
Nikkomycin pseudo-J is a tripeptide derivative of the nikkomycin class found in Streptomyces tendae, which has antifungal and antiinsect activities. Nikkomycin pseudo-J exerts its biological activity by competitively inhibiting chitin synthetase of fungi and insects .

HY-W089233

Boc-D-Glu-OtBu N-Boc-D-glutaMic acid 1-tert-butyl ester	Amino Acid Derivatives	Others
Boc-D-Glu-OtBu (N-Boc-D-glutaMic acid 1-tert-butyl ester) is an amino acid derivative with a Boc protecting group, which can be used to synthesize Adamant-1-yl tripeptide with immunostimulatory activity .

HY-15584

Taltobulin 3 Publications Verification HTI-286; SPA-110	Microtubule/Tubulin ADC Cytotoxin Apoptosis	Cancer
Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .

HY-15584A

Taltobulin trifluoroacetate 3 Publications Verification HTI-286 trifluoroacetate; SPA-110 trifluoroacetate	Microtubule/Tubulin ADC Cytotoxin Apoptosis	Cancer
Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .

HY-15584B

Taltobulin hydrochloride 3 Publications Verification HTI-286 hydrochloride; SPA-110 hydrochloride	Microtubule/Tubulin ADC Cytotoxin Apoptosis	Cancer
Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin hydrochloride inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis .

HY-P4296

H-Gly-Sar-Sar-OH	Amino Acid Derivatives	Others
H-Gly-Sar-Sar-OH is an orally active tripeptide. H-Gly-Sar-Sar-OH is transported through PepT1 within Caco-2 cells. H-Gly Sar Sar OH has potential applications in material transportation .

HY-139907

DG013A	Others	Inflammation/Immunology Cancer
DG013A is a phosphinic acid tripeptide mimetic inhibitor. DG013A displays significantly weak affinity for both ERAP1 (IC₅₀=33 nM) and ERAP2 (IC₅₀=11 nM). DG013A can be used for the research of autoimmune disease and cancer .

HY-136479

F0911-7667	Others	Cancer
F0911-7667 is a SIRT1 activator that induces autophagic cell death in U87MG and T98G cells by activating the AMPK-mTOR-ULK complex. CWR tripeptide was also identified as a SIRT1 activator that reduced p53 acetylation in IMR32 neuroblastoma cells and protected cells from cell death induced by Aβ fragments .

HY-W015236

H-Gly-Gly-Gly-OH Triglycine	Biochemical Assay Reagents	Others
H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-125039

N-Acetyl lysyltyrosylcysteine amide 2 Publications Verification	Glutathione Peroxidase	Cardiovascular Disease Neurological Disease
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation .

HY-129407

AAF-CMK TFA Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II	Others	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

HY-108137

Z-LVG-CHN2 2 Publications Verification	Cathepsin HSV SARS-CoV	Infection Inflammation/Immunology
Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC₅₀=190 nM) via inhibition of SARS-COV-2 3CL pro protease .

HY-P4292

H-Gly-Pro-Gly-NH2	HIV Amino Acid Derivatives	Infection
H-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 III_B and HIV-2 ROD with EC₅₀ values of 35 µM and 30 µM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research .

Cat. No.	Product Name	Type

HY-W015236

H-Gly-Gly-Gly-OH

Triglycine

Chelators

H-Gly-Gly-Gly-OH, also known as Triglycine, is a tripeptide composed of glycine, glycine and glycine, which are linked by peptide bonds. Often used as a model compound in the study of protein structure and function. Glycylglycylglycine also acts as a neurotransmitter in the central nervous system and has been shown to have antioxidant properties. Furthermore, it may have potential research roles in various diseases such as cancer, diabetes and neurodegenerative diseases.

HY-143686

ImmTher	Drug Delivery
ImmTher is a liposome-encapsulated lipophilic disaccharide tripeptide derivative of muramyl dipeptide. ImmTher can up-regulate specific monocyte cytokine genes and activate monocyte-mediated tumoricidal activity .

Cat. No.	Product Name	Target	Research Area

HY-P5244

Tripeptide-32	Peptides	Metabolic Disease
Tripeptide-32 is a bioactive peptide that targets the PER1 gene. Tripeptide-32 can regulate circadian rhythms and stimulate the synthesis of cellular repair proteins, with anti-aging activity .

HY-P5275

Tripeptide-41 CG-Lipoxyn	NF-κB	Metabolic Disease
Tripeptide-41(CG-Lipoxyn)isa bioactive peptide withreduce fat accumulationeffect and has been reported used as a cosmetic ingredient .

HY-P0046

Glycyl-L-histidyl-L-lysine 2 Publications Verification GHK; Tripeptide-1	Peptides	Neurological Disease Inflammation/Immunology
Glycyl-L-histidyl-L-lysine is a *tripeptide* consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance .

HY-P5262

Tripeptide-10	Peptides	Metabolic Disease
Tripeptide-10 is a bioactive peptide withanti-wrinkleeffect and has been reported used as a cosmetic ingredient .

HY-P5264

Tripeptide-8	Peptides	Inflammation/Immunology
Tripeptide-8 is a bioactive peptide withanti-inflammatoryeffect and has been reported used as a cosmetic ingredient .

HY-P5242

Tripeptide-10 citrulline T10-C	Peptides	Others
Tripeptide-10 citrulline (T10-C) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-A0299

H-Gly-Pro-Hyp-OH Tripeptide 29	Peptides	Others
HGly-Pro-Hyp-OH (Tripeptide 29) is an orally active bioactive peptide against UVB-induced skin aging and has been reported used as a cosmetic ingredient ^[1]

HY-P3519

ACV Tripeptide	Peptides	Others
ACV Tripeptide is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide is synthesized by a large non-ribosomal peptide synthase called ACV synthase, which is encoded by the 11 kb The pchAB gene encodes this enzyme .

HY-P4260

LPP Tripeptide	Peptides	Cardiovascular Disease
LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension .

HY-P10266

*Myristoyl tripeptide-1*	Peptides	Others
Myristoyl tripeptide-1 is the reaction product of Myristic acid (HY-N2041) and Tripeptide-1. Myristoyl tripeptide-1 is utilized in cosmetics as the conditioning agent of skin .

HY-P0047A

*Palmitoyl Tripeptide-1 hydrochloride*	Peptides	Others
Palmitoyl tripeptide-1 hydrochloride is a fatty acid modified polypeptide. Palmitoyl Tripeptide-1 has good wrinkle-removing effect .

HY-P0047

*Palmitoyl Tripeptide-1*	Peptides	Others
Palmitoyl tripeptide-1 is a fatty acid modified polypeptide. Palmitoyl Tripeptide-1 has good wrinkle-removing effect .

HY-P0104

*Palmitoyl tripeptide-38*	Reactive Oxygen Species	Metabolic Disease
Palmitoyl tripeptide-38 is a bioactive peptide with anti-aging effect .

HY-P3519A

*ACV Tripeptide* TFA**	Peptides	Others
ACV Tripeptide TFA is the TFA form of ACV Tripeptide (HY-P3519). ACV Tripeptide TFA is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide TFA is synthesized by a large non-ribosomal peptide synthase called ACV synthase .

HY-P5238

*Trifluoroacetyl tripeptide-2*	Peptides	Others
Trifluoroacetyl tripeptide-2 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-P5250

*Palmitoyl tripeptide-5*	Peptides	Others
Palmitoyl tripeptide-5 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-P0063

Copper tripeptide 1 Publications Verification GHK-Cu	Endogenous Metabolite	Inflammation/Immunology
Copper tripeptide (GHK-Cu) is a *tripeptide. During wound healing, copper tripeptide* may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .

HY-P5226

*Palmitoyl tripeptide-8*	Peptides	Inflammation/Immunology
Palmitoyl tripeptide-8 s a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient .

HY-P5230

*Manganese tripeptide-1*	Peptides	Others
Manganese tripeptide-1 is a bioactive peptide with anti-wrinkle and reducing skin hyperpigmentation effect, and has been reported used as a cosmetic ingredient .

HY-P5252

*Diaminopropionoyl tripeptide-33*	Tyrosinase	Metabolic Disease
Diaminopropionoyl tripeptide-33isa bioactive peptide with protects skin cells from UVA-induced DNA damages and has been reported used as a cosmetic ingredient .

HY-P5240

*Acetyl tripeptide-30 citrulline*	Peptides	Others
Acetyl tripeptide-30 citrulline is a bioactive peptide with anti-wrinkle effect and has been reported used as a cosmetic ingredient .

HY-P5243

*Copper tripeptide-3* AHK-Cu	Peptides	Others
Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient .

HY-125616

*Biotinoyl tripeptide-1* Biotinyl-GHK; Bio-GHK	Peptides	Others
Biotinoyl tripeptide-1 (Biotinyl-GHK; Bio-GHK)is a bioactive peptide with hair growth effect and has been reported used as a cosmetic ingredient .

HY-148337

Thr-Val-Leu	Peptides	Others
Thr-Val-Leu is a central nervous system tripeptide .

HY-P5962

Fmoc-Gly-Pro-Hyp(OtBu)-OH TFA	Peptides	Others
Fmoc-Gly-Pro-Hyp(OtBu)-OH (TFA) is a tripeptide that can be used in peptide synthesis .

HY-W009215

H-Met-Ala-Ser-OH L-Met-L-Ala-L-Ser	Peptides	Others
H-Met-Ala-Ser-OH (L-Met-L-Ala-L-Ser) is a tripeptide. H-Met-Ala-Ser-OH can act as a formyl receptor .

HY-114424

H-Ile-Pro-Pro-OH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
H-Ile-Pro-Pro-OH, a milk-derived peptide , inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM . Antihypertensive tripeptides .

HY-114424A

H-Ile-Pro-Pro-OH hydrochloride 1 Publications Verification	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide , inhibits angiotensin-converting enzyme (ACE) with an IC₅₀ of 5 μM . Antihypertensive tripeptides .

HY-106263B

Tyroserleutide hydrochloride	Peptides	Cancer
Tyroserleutide hydrochloride, isolated from the degradation products of porcine spleen , is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo .

HY-106263

Tyroserleutide	Peptides	Cancer
Tyroserleutide (YSL), isolated from the degradation products of porcine spleen , is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo .

HY-106263A

Tyroserleutide TFA	Peptides	Cancer
Tyroserleutide TFA, isolated from the degradation products of porcine spleen , is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo .

HY-P2788

Hyp-Phe-Phe	Peptides	Others
Hyp-Phe-Phe is a tripeptide that forms helical-like sheets via aromatic interactions of the Phe rings to comprise a cross helical architecture. Hyp-Phe-Phe possesses a high shear piezoelectricity and acts as piezoelectric material .

HY-P10208

RKH	Toll-like Receptor (TLR)	Infection
PKH is a TLR4 antagonist. PKH is a novel tripeptide and can be isolated from Akkermansia muciniphila. RKH reduces sepsis-induced inflammatory cell activation and proinflammatory factor overproduction .

HY-P3752

Gly-Ala-Tyr	Peptides	Others
Gly-Ala-Tyr is a *tripeptide* composed of L-glycine, alanine and L-tyrosine joined in sequence by peptide linkages. Ala-Gly-Tyr is functionally related to L-alanine, glycine and L-tyrosine.

HY-P3424

NH2-AKK-COOH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC₅₀s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively .

HY-W016012

Glu-Glu	Amino Acid Derivatives	Others
Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption .

HY-117483

Gly-Pro-Glu	Peptides	Neurological Disease
Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC₅₀ value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .

HY-13634

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

HY-13634A

Ezatiostat Maximum Cited Publications 7 Publications Verification TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

HY-P3534

EILDV (human, bovine, rat)	Peptides	Cancer
EILDV (human, bovine, rat) is an analogue of the active pentapeptide. EILDV (human, bovine, rat) has active tripeptide amino acid sequence LDV that is conserved in human, bovine, rat. EILDV (human, bovine, rat) can be used for the research of cell adhesion .

HY-P4299

Tri-aspartic acid	Peptides	Others
Tri-aspartic acid is a tripeptide .

HY-W010873

Z-Pro-Leu-Gly-OEt	Amino Acid Derivatives	Others
Z-Pro-Leu-Gly-OEt is a tripeptide .

HY-P4365

D-Pro-Pro-Glu	Peptides	Others
D-Pro-Pro-Glu is a tripeptide catalyst .

HY-P10118

Cathepsin L-IN-3	Cathepsin	Others
Cathepsin L-IN-3 is a tripeptide-sized cathepsin L inhibitor.

HY-P4231

H-Gly-Ala-Hyp-OH	Peptides	Others
H-Gly-Ala-Hyp-OH is a collagen tripeptide fragment .

HY-P4362

Suc-Ala-Pro-Ala-AMC	Elastase	Others
Suc-Ala-Pro-Ala-AMC is a tripeptide substrate of elastase .

HY-P4671

Nle-Arg-Phe-NH2 acetate	Peptides	Others
Nle-Arg-Phe-NH2 (acetate) is a tripeptide compound, usually in the form of acetate .

HY-P0296

Gly-Phe-Arg	Peptides	Others
Gly-Phe-Arg is a superpotent synthetic tripeptide mimics of the mud-crab pumping pheromone.

HY-P5037

Fmoc-Gly-Pro-Hyp-OH	Peptides	Others
Fmoc-Gly-Pro-Hyp-OH is a tripeptide that can be used in peptide synthesis .

HY-P4242

Ala-Gly-Ala	Peptides	Others
Ala-Gly-Ala is a prototype of a general tripeptide Xxx-Gly-Zzz. Except glycine and proline, there can be 18 possible amino acids for Xxx and another 18 amino acids for Zzz. Ala-Gly-Ala can be used as a model for up to 324 possible motifs of this kind of tripeptide .

Cat. No.	Product Name	Target	Research Area

HY-P990027

Izeltabart	ADC Antibody	Cancer
Izeltabart is a high-affinity humanized antibody targeting ADAM9. Izeltabart can be used as ADC Antibody for site-specific conjugation with Maytansinoid-based DM21-C (a Drug-Linker Conjugates for ADC), to synthesize IMGC936 (Antibody-Drug Conjugates (ADCs)) with strong anti-cancer activity. DM21-C is composed of Maytansinoid (microtubule inhibitor) and a stable tripeptide linker. IMGC936 exhibits cytotoxicity against ADAM9-positive human tumor cell lines and potent antitumor activity in xenograft tumor models .

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