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Results for "

glutathione-S-transferase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glutathione S-transferase (30) Apoptosis (7) Autophagy (1) Bacterial (2) Calcium Channel (4) Cytochrome P450 (3) DNA Alkylator/Crosslinker (1) DNA-PK (1) Endogenous Metabolite (1) Keap1-Nrf2 (1) NF-κB (4) NO Synthase (2) NOD-like Receptor (NLR) (1) P-glycoprotein (1) Parasite (1) Pyroptosis (1)
By Research Areas:	Cancer (26) Infection (3) Inflammation/Immunology (8) Metabolic Disease (6) Neurological Disease (1)
Click Chemistry:	Alkynes (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Targets Recommended: Glutathione S-transferase Glutathione Peroxidase Glutathione Reductase Farnesyl Transferase OGT NAMPT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2961

*Glutathione S-transferase*	Others	Others
Glutathione S-transferase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N1282

Seneciphylline	Glutathione S-transferase Cytochrome P450	Cancer
Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and *glutathione-S-transferase* but causes reduction of cytochrome P-450 and related monooxygenase activities .

HY-W013754

S-Hexylglutathione	Others	Others
S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against *glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase* and glutathione peroxidase .

HY-115673

LAS17 1 Publications Verification	Glutathione S-transferase	Cancer
LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione?S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC₅₀ of 0.5 μM . LAS17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N7227

Anonaine	Glutathione S-transferase Parasite	Infection Cancer
Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor .

HY-160874

GST-FH.4	Glutathione S-transferase	Metabolic Disease
GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC₅₀ of 24.38 μM .

HY-N1282R

Seneciphylline (Standard)	Glutathione S-transferase Cytochrome P450	Cancer
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities .

HY-137330

S-(2,4-Dinitrophenyl)glutathione	Endogenous Metabolite	Metabolic Disease
S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an K_i value of 30 µM .

HY-W013744

S-Octylglutathione	Others	Others
S-Octylglutathione is a competitive *glutathione S-transferase* (GST) inhibitor .

HY-118045

Cysfluoretin	Glutathione S-transferase	Cancer
Cysfluoretin is an inhibitor of *glutathione S-transferase* with an IC₅₀ value of 9.4 μg/mL .

HY-160875

GST-FH.1	Glutathione S-transferase	Metabolic Disease
GST-FH.1 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC₅₀ of 0.32 μM .

HY-160926

16-Oxocafestol	Glutathione S-transferase	Cancer
16-Oxocafestol enhances levels of glutathione S-transferase (GST) and tissue sulfhydryl in liver and in small bowel mucosa .

HY-111530

GSTO1-IN-1 3 Publications Verification	Glutathione S-transferase	Cancer
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC₅₀ of 31 nM.

HY-133199

Benastatin A	Glutathione S-transferase	Others
Benastatin A is an inhibitor of glutathione S-transferase, which can be isolated from Streptomyces MI384-DF12 .

HY-167920

Glutathione sulfonate S-Sulfoglutathione	Others	Cancer
Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme .

HY-16123

Canfosfamide hydrochloride	DNA Alkylator/Crosslinker	Cancer
Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.

HY-149419

GST-IN-1	Glutathione S-transferase	Others
GST-IN-1 (compound 16) is a glutathione S-transferase (GST) inhibitor with IC50s of 1.55 μM (sjGST) and 2.02 μM (hGSTM2), respectively.

HY-N11778

Bequinostatin C	Bacterial	Infection
Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC₅₀=40 μg/mL for human GSTP1).

HY-116726

Crambene	Glutathione S-transferase	Cancer
Crambene is an orally active cyanide compound isolated from cruciferous vegetables. Crambene has a cancer-preventive effect and induces significant upregulation of quinone reductase and *glutathione S-transferase* in vitro and in vivo .

HY-112534

GSTO-IN-2 2 Publications Verification	Glutathione S-transferase	Cancer
GSTO-IN-2 is a *glutathione S-transferase* inhibitor with IC₅₀s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1.

HY-N1916

Coniferyl ferulate	Glutathione S-transferase P-glycoprotein	Cancer
Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST), reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM.

HY-W020788

Benoxacor CGA 154281	Glutathione S-transferase	Others
Benoxacor (CGA 154281) is a herbicide safener that can protect crops from the toxicity of herbicides. Benoxacor can enhance the activity of glutathione S-transferase (GST) in corn, effectively inducing detoxification of herbicides in corn .

HY-N1963

Curzerene	Glutathione S-transferase Apoptosis	Cancer
Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis .

HY-N2560

Senecionine Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin	Others	Metabolic Disease
Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) .

HY-13634B

TLK117 1 Publications Verification TER117	Glutathione S-transferase	Inflammation/Immunology Cancer
TLK117, the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1–1 (GSTP1-1) with a K_i of 0.4 μM for GSTP. TLK117 also competitively inhibits glyoxalase I with a K_i of 0.56 μM.

HY-126329

AZD9898	Glutathione S-transferase	Inflammation/Immunology
AZD9898 is an orally active *leukotriene-C4 synthetase (LTC4S, glutathione S-transferase* II) inhibitor, with an IC₅₀** of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma .

HY-W020788R

Benoxacor (Standard)	Glutathione S-transferase	Others
Benoxacor (Standard) is the analytical standard of Benoxacor. This product is intended for research and analytical applications. Benoxacor (CGA 154281) is a herbicide safener that can protect crops from the toxicity of herbicides. Benoxacor can enhance the activity of glutathione S-transferase (GST) in corn, effectively inducing detoxification of herbicides in corn .

HY-N1963R

Curzerene (Standard)	Glutathione S-transferase Apoptosis	Cancer
Curzerene (Standard) is the analytical standard of Curzerene. This product is intended for research and analytical applications. Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis .

HY-W154265

2,2′-Dihydroxychalcone	Glutathione S-transferase Apoptosis	Cancer
2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC₅₀ of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties .

HY-N2560R

Senecionine (Standard)	Others	Metabolic Disease
Senecionine (Standard) is the analytical standard of Senecionine. This product is intended for research and analytical applications. Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) .

HY-160455

GSTP1-1 inhibitor 1	Glutathione S-transferase	Cancer
GSTP1-1 inhibitor 1 (compound 6b) is an irreversible, long-acting, glutathione S-transferase inhibitor with an IC₅₀ of 21 μM targeting GSTP_1-1 . GSTP_1-1 is a key tumor suppressor target, and GSTP1-1 inhibitor 1 has potential anticancer activity .

HY-13634

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

HY-13634A

Ezatiostat Maximum Cited Publications 7 Publications Verification TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

HY-B1640

Ethacrynic acid 4 Publications Verification Etacrynic acid	Glutathione S-transferase NF-κB Calcium Channel NO Synthase	Inflammation/Immunology Cancer
Ethacrynic acid has anti-inflammatory and anticancer activity. Ethacrynic acid is an orally active diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways. Ethacrynic acid is a radiosensitizer. Ethacrynic acid can inhibit airway smooth muscle (ASM) contraction in mice. Ethacrynic acid can increase the outflow of aqueous humor from the eye for the study of glaucoma .

HY-16124

Canfosfamide TLK-286; TER286	DNA-PK Apoptosis	Cancer
Canfosfamide (TLK-286, TER286) is a glutathione analogue prodrug that is activated by glutathione S-transferase P1-1 and induces apoptosis. Canfosfamide also inhibits the catalytic kinase activity of DNA-dependent protein kinase (DNA-PK). Canfosfamide produces an anticancer alkylating agent and a glutathione derivative after activation. Canfosfamide can be used to research malignancies .

HY-115822

α-Fluoromethylhistidine dihydrochloride	Others	Metabolic Disease
α-Fluoromethylhistidine dihydrochloride is a potent irreversible inhibitor of histidine decarboxylase (HDC) and glutathione S-transferase, demonstrating significant potential in studying histidine metabolism and drug metabolism processes. α-Fluoromethylhistidine dihydrochloride offers an effective approach to inhibit enzymes involved in these metabolic pathways. α-Fluoromethylhistidine dihydrochloride has implications for drug development by revealing off-target effects that may influence physiological drug metabolism and elimination mechanisms.

HY-B1640A

Ethacrynic acid sodium Etacrynic acid sodium; Sodium etacrynate	NF-κB Glutathione S-transferase Calcium Channel NO Synthase	Inflammation/Immunology Cancer
Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice .

HY-135318

NBDHEX 1 Publications Verification	Apoptosis Autophagy Glutathione S-transferase	Cancer
NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor .

HY-108538

Ethacrynic acid D5	Glutathione S-transferase NF-κB Calcium Channel	Inflammation/Immunology
Ethacrynic acid D5 is a deuterium labeled Ethacrynic acid. Ethacrynic acid is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice .

HY-133217

Benastatin C	Bacterial	Infection
Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC₅₀=24 μg/mL for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC₅₀=10 μg/mL). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.

HY-B1640R

Ethacrynic acid (Standard) 4 Publications Verification Etacrynic acid (Standard)	Glutathione S-transferase NF-κB Calcium Channel	Inflammation/Immunology Cancer
Ethacrynic acid (Standard) is the analytical standard of Ethacrynic acid. This product is intended for research and analytical applications. Ethacrynic acid (Etacrynic acid) is a diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice .

HY-169058

GSTP1-1 inhibitor 2	Glutathione S-transferase	Cancer
GSTP1-1 inhibitor 2 (Compound 5g) is an hGSTP1-1 (glutathione S-transferase P1-1) inhibitor with an IC₅₀ value of 12.2 μM. GSTP1-1 inhibitor 2 exhibits significant cytotoxicity against DU-145, PC3, and MCF-7 cell lines, with CC₅₀ values of 36.6 μM, 11.9 μM, and 17.4 μM, respectively. It can be used in cancer research .

HY-147517

Keap1-Nrf2-IN-9	Keap1-Nrf2	Neurological Disease Inflammation/Immunology
Keap1-Nrf2-IN-9 (compound 11) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with an IC₅₀ of 0.575 µM. Keap1-Nrf2-IN-9 increases the expression of Nrf2 target genes including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Keap1-Nrf2-IN-9 shows not cytotoxic activity in ARPE19 cells .

HY-128369

Acid Yellow 36 Metanil Yellow	Cytochrome P450	Others
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

HY-163179

NLRP3-IN-28	NOD-like Receptor (NLR) Pyroptosis	Inflammation/Immunology
NLRP3-IN-28 (compound N77) is a potent inhibitor of NLRP3. NLRP3-IN-28 inhibits Nigericin (HY-127019)-induced pyroptosis with an EC₅₀ of 0.07μM. NLRP3-IN-28 alleviates the inflammatory reaction in vivo .

Cat. No.	Product Name	Type

HY-128369

Acid Yellow 36 Metanil Yellow	Dyes
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes .

Cat. No.	Product Name	Target	Research Area

HY-13634B

TLK117 1 Publications Verification TER117	Glutathione S-transferase	Inflammation/Immunology Cancer
TLK117, the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1–1 (GSTP1-1) with a K_i of 0.4 μM for GSTP. TLK117 also competitively inhibits glyoxalase I with a K_i of 0.56 μM.

HY-13634A

Ezatiostat Maximum Cited Publications 7 Publications Verification TER199(free base); TLK199	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat (TER199 free base; TLK199) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat has the potential for myelodysplastic syndrome (MDS) treatment .

HY-137330

S-(2,4-Dinitrophenyl)glutathione	Endogenous Metabolite	Metabolic Disease
S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an K_i value of 30 µM .

HY-13634

Ezatiostat hydrochloride TER199; TLK199 hydrochloride	Glutathione S-transferase Apoptosis	Cancer
Ezatiostat hydrochloride (TER199; TLK199 hydrochloride) is a tripeptide analog of glutathione and is a selective and orally active glutathione S-transferase P1-1 (GSTP1) inhibitor. Ezatiostat hydrochloride leads to JNK activation by inhibiting GSTP1. Ezatiostat hydrochloride stimulates both lymphocyte production and bone marrow progenitor proliferation. Ezatiostat hydrochloride has the potential for myelodysplastic syndrome (MDS) treatment .

Species:	Human (12) Rat (1)
Tag:	His (12) Tag Free (3) Myc (2) GST (2)
Source:	HEK293 (3) E. coli Cell-free (1) Sf9 insect cells (1) E. coli (11)

Cat. No.	Compare	Product Name	Species	Source

HY-P75800

	GSTK1 Protein, Human glutathione S-transferase kappa 1; GST 13-13; GSTK1-1; glutathione S-transferase subunit 13	Human	E. coli
	The GSTK1 protein acts as a glutathione S-transferase, promoting the binding of glutathione to exogenous and endogenous compounds, mainly through the model substrate 1-chloro-2,4-dinitrobenzene (CDNB). active activity. This enzymatic activity plays a vital role in the detoxification process, assisting in the binding of glutathione to various substrates. GSTK1 Protein, Human is the recombinant human-derived GSTK1 protein, expressed by E. coli , with tag free.

HY-P72215

	GSTP1 Protein, Human (His) Deafness; Deafness X-linked 7; DFN7; FAEES3; Fatty Acid Ethyl Ester Synthase III ; glutathione S transferase 3; glutathione S transferase Pi; glutathione S-transferase P; glutathione S-transferase pi 1; GST class-pi; GST3; GSTP; Gstp1; GSTP1-1; GSTP1_HUMAN; PI; X linked 7	Human	E. coli
	The GSTP1 protein is critical for binding reduced glutathione to a variety of hydrophobic electrophiles, actively forming glutathione conjugates of PGA2 and PGJ2. Documented studies highlight its involvement in hepoxilin regioisomer synthesis, emphasizing the versatility of GSTP1 in processing substrates. GSTP1 Protein, Human (His) is the recombinant human-derived GSTP1 protein, expressed by E. coli , with N-10*His labeled tag. The total length of GSTP1 Protein, Human (His) is 209 a.a., with molecular weight of ~25 kDa.

HY-P75153

	GSTA1 Protein, Human (HEK293, His, solution) glutathione S-transferase A1; GST-epsilon; GSTA1-1; GTH1; GSTA1	Human	HEK293
	The GSTA1 protein catalyzes the attack of glutathione on various compounds, forming conjugates of PGA2 and PGJ2. It also converts AD into D4-androstene-3,17-dione, contributing to hormone biosynthesis. Additionally, it participates in the metabolism of oxidized linoleic acid through its peroxidase activity against 13-HPODE. GSTA1 Protein, Human (HEK293, His, solution) is the recombinant human-derived GSTA1 protein, expressed by HEK293 , with C-His labeled tag. The total length of GSTA1 Protein, Human (HEK293, His, solution) is 222 a.a., with molecular weight of ~26 kDa.

HY-P75153A

	GSTA1 Protein, Human (HEK293, C-His) 1 Publications Verification glutathione S-transferase A1; GST-epsilon; GSTA1-1; GTH1; GSTA1	Human	HEK293
	The GSTA1 protein catalyzes the attack of glutathione on various compounds, forming conjugates of PGA2 and PGJ2. It also converts AD into D4-androstene-3,17-dione, contributing to hormone biosynthesis. Additionally, it participates in the metabolism of oxidized linoleic acid through its peroxidase activity against 13-HPODE. GSTA1 Protein, Human (HEK293, C-His) is the recombinant human-derived GSTA1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GSTA1 Protein, Human (HEK293, C-His) is 222 a.a., with molecular weight of ~26 kDa.

HY-P75802

	GSTT2B Protein, Human (HEK293, His) glutathione S-transferase theta-2B; GST class-theta-2; GSTT2B; GSTT2	Human	HEK293
	GSTT2B protein, crucial in conjugating reduced glutathione to hydrophobic electrophiles, is essential for cellular detoxification. Its sulfatase activity adds to its multifunctional role in cellular processes. The combined glutathione conjugation and sulfatase function underscore GSTT2B's versatility in handling diverse substrates, emphasizing its significance in cellular detoxification mechanisms. GSTT2B Protein, Human (HEK293, His) is the recombinant human-derived GSTT2B protein, expressed by HEK293 , with C-His labeled tag. The total length of GSTT2B Protein, Human (HEK293, His) is 244 a.a..

HY-P75152

	GSTM2 Protein, Human (His) glutathione S-transferase Mu 2; GST class-mu 2; GSTM2-2; GST4	Human	E. coli
	GSTM2 protein is pivotal in conjugating reduced glutathione to diverse hydrophobic electrophiles and actively participates in synthesizing hepoxilin regioisomers, as documented. This underscores GSTM2's multifunctional nature, emphasizing its role in detoxification and forming unique molecular species, contributing to the broader cellular response to various electrophilic compounds. GSTM2 Protein, Human (His) is the recombinant human-derived GSTM2 protein, expressed by E. coli , with N-His labeled tag.

HY-P700381

	Glutathione S-transferase kappa 1/GSTK1 Protein, Human (GST) glutathione S-transferase kappa 1; GST 13-13; GSTK1-1; glutathione S-transferase subunit 13	Human	E. coli
	The GSTK1 protein acts as a glutathione S-transferase, promoting the binding of glutathione to exogenous and endogenous compounds, mainly through the model substrate 1-chloro-2,4-dinitrobenzene (CDNB). active activity. This enzymatic activity plays a vital role in the detoxification process, assisting in the binding of glutathione to various substrates. Glutathione S-transferase kappa 1/GSTK1 Protein, Human (GST) is the recombinant human-derived Glutathione S-transferase kappa 1/GSTK1 protein, expressed by E. coli , with N-GST labeled tag.

HY-P702379

	MGST2 Protein, Human (Cell-Free, His) Microsomal glutathione S-transferase 2; glutathione peroxidase MGST2; 1.11.1.-; Leukotriene C4 synthase MGST2; 4.4.1.20; Microsomal glutathione S-transferase II; Microsomal GST-II	Human	E. coli Cell-free
	As a multifunctional enzyme, MGST2 protein catalyzes the synthesis of cyclic ADP-β-D-ribose (cADPR) from NAD(+) and subsequently hydrolyzes cADPR into ADP-D-ribose (ADPR). This dual function makes MGST2 a key player in regulating intracellular calcium mobilization, as cADPR acts as an endogenous second messenger that triggers the release of intracellular stored calcium. MGST2 Protein, Human (Cell-Free, His) is the recombinant human-derived MGST2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of MGST2 Protein, Human (Cell-Free, His) is 147 a.a., with molecular weight of 19.4 kDa.

HY-P72214

	GSTP1 Protein, Cricetulus longicaudatus (His-Myc) GSTP1glutathione S-transferase P; EC 2.5.1.18; GST class-pi	Others	E. coli
	GSTP1, a key protein, aids in cellular detoxification by conjugating reduced glutathione to hydrophobic electrophiles. It also forms glutathione conjugates for PGA2 and PGJ2 and contributes to hepoxilin synthesis. Additionally, GSTP1 regulates CDK5 activity, preventing neurodegeneration. This versatile enzyme safeguards cellular homeostasis and plays a crucial role in various biochemical pathways. GSTP1 Protein, Cricetulus longicaudatus (His-Myc) is the recombinant GSTP1 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of GSTP1 Protein, Cricetulus longicaudatus (His-Myc) is 210 a.a., with molecular weight of ~28.7 kDa.

HY-P72050

	GSTP1 Protein, Cricetulus longicaudatus (sf9, His-Myc) GSTP1glutathione S-transferase P; EC 2.5.1.18; GST class-pi	Others	Sf9 insect cells
	GSTP1, a key protein, aids in cellular detoxification by conjugating reduced glutathione to hydrophobic electrophiles. It also forms glutathione conjugates for PGA2 and PGJ2 and contributes to hepoxilin synthesis. Additionally, GSTP1 regulates CDK5 activity, preventing neurodegeneration. This versatile enzyme safeguards cellular homeostasis and plays a crucial role in various biochemical pathways. GSTP1 Protein, Cricetulus longicaudatus (sf9, His-Myc) is the recombinant GSTP1 protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag.

HY-P70150

	GSTP1 Protein, Human rHuglutathione S-transferase P/GSTP1; glutathione S-transferase P; GSTP1; GST class-pi; GSTP1-1; FAEES3; GST3;	Human	E. coli
	Glutathione S-transferase P (GSTP1) is a member of GSTs family and plays an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 enables JUN kinase binding activity; glutathione transferase activity; and kinase regulator activity and is involved in negative regulation of cell population proliferation, intracellular signal transduction and macromolecule metabolic process as well. GSTP1 Protein, Human is the recombinant human-derived GSTP1 protein, expressed by E. coli , with tag free. The total length of GSTP1 Protein, Human is 210 a.a., with molecular weight of ~23.66 kDa.

HY-P72217

	GSTP1 Protein, Rat (His) Gstp1; glutathione S-transferase P; EC 2.5.1.18; Chain 7; GST 7-7; GST class-pi	Rat	E. coli
	GSTP1 protein conjugates reduced glutathione to hydrophobic electrophiles, forms glutathione conjugates of PGA2 and PGJ2, and contributes to hepoxilin production.It also regulates CDK5 activity by facilitating p25/p35 translocation, preventing neurodegeneration.GSTP1 Protein, Rat (His) is the recombinant rat-derived GSTP1 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P75801

	GSTM5 Protein, Human (N-His) glutathione S-transferase Mu 5; GST class-mu 5; GSTM5-5; GSTM5	Human	E. coli
	GSTM5 protein is pivotal in conjugating reduced glutathione to diverse hydrophobic electrophiles, crucial for cellular detoxification. Its enzymatic activity, addressing both exogenous and endogenous compounds, is essential for eliminating harmful substances and maintaining cellular homeostasis, highlighting GSTM5's protective role against toxic insults. GSTM5 Protein, Human (N-His) is the recombinant human-derived GSTM5 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P75152A

	GSTM2 Protein, Human (N-His) glutathione S-transferase Mu 2; GST class-mu 2; GSTM2-2; GST4	Human	E. coli
	GSTM2 protein is pivotal in conjugating reduced glutathione to diverse hydrophobic electrophiles and actively participates in synthesizing hepoxilin regioisomers, as documented. This underscores GSTM2's multifunctional nature, emphasizing its role in detoxification and forming unique molecular species, contributing to the broader cellular response to various electrophilic compounds. GSTM2 Protein, Human (N-His) is the recombinant human-derived GSTM2, expressed by E. coli , with N-6*His labeled tag. The total length of GSTM2 Protein, Human (N-His) is 218 a.a.,

HY-P70206A

	Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) rHuMaleylacetoacetate isomerase/GSTZ1, His; Maleylacetoacetate Isomerase; MAAI; GSTZ1-1; glutathione S-transferase Zeta 1; GSTZ1	Human	E. coli
	The maleylacetoacetate isomerase/GSTZ1 protein is a member of the GST superfamily and detoxifies electrophilic molecules. It converts maleylacetoacetate to fumarylacetoacetate, a key step in phenylalanine/tyrosine degradation. Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is the recombinant human-derived Maleylacetoacetate isomerase/GSTZ1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Maleylacetoacetate isomerase/GSTZ1 Protein, Human (N-His) is 215 a.a., with molecular weight of ~25 kDa.

HY-P70270

	GST Protein, Schistosoma Japonicum 1 Publications Verification rSchglutathione S-transferase class-mu 26 kDa isozyme; glutathione S-transferase class-mu 26 kDa isozyme; GST 26; Sj26 antigen; SjGST	Others	E. coli
	The GST (Glutathione S-transferase) protein is vital for conjugating reduced glutathione to hydrophobic electrophiles, essential for cellular detoxification and defense. GST isoenzymes play a central role in parasites' detoxification systems, indicating a crucial defense role. Additionally, GST may enhance haematin solubility in parasite guts, highlighting its multifaceted contributions to cellular and organismal processes. GST Protein, Schistosoma Japonicum is the recombinant GST protein, expressed by E. coli , with tag free. The total length of GST Protein, Schistosoma Japonicum is 218 a.a., with molecular weight of ~28.0 kDa.

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HY-P80148A

	GST-Tag Antibody (YA863) glutathione S transferase antibody; glutathione S-transferase class-mu 26 kDa isozyme antibody; GST antibody; Sj26 antigen antibody; SjGST antibody	WB, ICC/IF, IP	Species independent
	The glutathione S-transferase (GST) family of enzymes comprises a long list of cytosolic, mitochondrial, and microsomal proteins that are capable of multiple reactions with a multitude of substrates, both endogenous and xenobiotic. Mammalian cytosolic GSTs are dimeric both subunits being from the same class of GSTs. The monomers are in the range of 22–29 kDa. Glutathione S-transferase is used to create the “GST gene fusion system” in genetic engineering. Here, GST is used to purify and detect proteins of interest.

HY-P83183

	Glutathione S Transferase mu 1 Antibody (YA2928) MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; MGC26563; GSTM1a-1a; GSTM1b-1b	WB	Human, Hamster
	Glutathione S Transferase mu 1 Antibody (YA2928) is a biotin-conjugated non-conjugated IgG antibody, targeting Glutathione S Transferase mu 1, with a predicted molecular weight of 26 kDa (observed band size: 26 kDa). Glutathione S Transferase mu 1 Antibody (YA2928) can be used for WB experiment in human, hamster background.

HY-P81277

	GST3 Antibody (YA975) GSTP1; FAEES3; GST3; glutathione S-transferase P; GST class-pi; GSTP1-1	WB, IHC-F, IHC-P, ICC/IF, FC	Human
	GST3 Antibody (YA975) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA975), targeting GST3, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). GST3 Antibody (YA975) can be used for WB, IHC-F, IHC-P, ICC/IF, FC experiment in human background.

HY-P81277A

	GST3 Antibody (YA976) GSTP1; FAEES3; GST3; glutathione S-transferase P; GST class-pi; GSTP1-1	IHC-P	Human
	GST3 Antibody (YA976) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA976), targeting GST3. GST3 Antibody (YA976) can be used for IHC-P experiment in human background.

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HY-115673

LAS17 1 Publications Verification		Alkynes
LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione?S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC₅₀ of 0.5 μM . LAS17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132913

Cyclopropenone probe 1		Alkynes
Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1), by covalently binding at the catalytic active site. Cyclopropenone probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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