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Results for "

muscle-relaxant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Adrenergic Receptor (1) Apoptosis (5) Autophagy (4) Biochemical Assay Reagents (1) Calcium Channel (11) Caspase (2) Cholinesterase (ChE) (5) Cytochrome P450 (4) Drug Metabolite (3) Endogenous Metabolite (6) GABA Receptor (9) Glutathione Reductase (1) iGluR (5) Isotope-Labeled Compounds (7) mAChR (4) nAChR (5) NF-κB (4) PGC-1α (4) Potassium Channel (1) Prostaglandin Receptor (1) Serotonin Transporter (2) Sodium Channel (6)
By Research Areas:	Cancer (8) Cardiovascular Disease (2) Inflammation/Immunology (17) Metabolic Disease (6) Neurological Disease (72)

By Targets:

5-HT Receptor (3)

Adrenergic Receptor (1)

Apoptosis (5)

Autophagy (4)

Biochemical Assay Reagents (1)

Calcium Channel (11)

Caspase (2)

Cholinesterase (ChE) (5)

Cytochrome P450 (4)

Drug Metabolite (3)

Endogenous Metabolite (6)

GABA Receptor (9)

Glutathione Reductase (1)

iGluR (5)

Isotope-Labeled Compounds (7)

mAChR (4)

nAChR (5)

NF-κB (4)

PGC-1α (4)

Potassium Channel (1)

Prostaglandin Receptor (1)

Serotonin Transporter (2)

Sodium Channel (6)

By Research Areas:

Cancer (8)

Cardiovascular Disease (2)

Inflammation/Immunology (17)

Metabolic Disease (6)

Neurological Disease (72)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W052144

(±) Anabasine 2 Publications Verification	Endogenous Metabolite	Others
(±) Anabasine is a biphasic muscle relaxant.

HY-101237

DHBP dibromide Diheptylviologen dibromide	Calcium Channel	Cardiovascular Disease Neurological Disease
DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

HY-101808

Doxefazepam SAS-643	GABA Receptor	Neurological Disease
Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsan and skeletal muscle relaxant properties.

HY-B1343

Pridinol mesylate	Cholinesterase (ChE)	Neurological Disease
Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-B1230

Camylofine	mAChR	Neurological Disease
Camylofin is an antimuscarinic, is a smooth muscle relaxant

HY-100159

Ipenoxazone MLV-6976; NC-1200	Others	Neurological Disease
Ipenoxazone is a potent and centrally acting muscle relaxant.

HY-121130

Dacuronium 17-hydroxypancuronium	Others	Neurological Disease
Dacuronium (17-hydroxypancuronium) is a steroid muscle relaxant .

HY-100159A

Ipenoxazone hydrochloride MLV-6976 hydrochloride; NC-1200 hydrochloride	Others	Neurological Disease
Ipenoxazone (MLV-6976) hydrochloride is a potent and centrally acting muscle relaxant.

HY-121340

Emylcamate	Others	Neurological Disease
Emylcamate is a potent muscle relaxant. Emylcamate has the potential for the research of neurological diseases .

HY-W052144S

(±) Anabasine-d4 dihydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Others
(±) Anabasine-d₄ (dihydrochloride) is deuterium labeled (±) Anabasine. (±) Anabasine is a biphasic muscle relaxant.

HY-B1343A

Pridinol	Cholinesterase (ChE)	Neurological Disease
Pridinol is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-B1139A

Tolperisone	Others	Neurological Disease
Tolperisone, a centrally acting muscle relaxant, is utilized for alleviating symptoms of spasticity and muscle spasms.

HY-106888A

CS-722	Endogenous Metabolite	Neurological Disease
CS-722 is a centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-B1462

Chlorzoxazone 2 Publications Verification	Cytochrome P450	Inflammation/Immunology
Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort.

HY-167659

Isomylamine hydrochloride	Biochemical Assay Reagents	Neurological Disease
Isomylamine hydrochloride is a spasmolytic and smooth muscle relaxant that can be utilized in relevant research or chemical synthesis .

HY-165544

Decamethonium chloride	Others	Neurological Disease
Decamethonium chloride is a depolarizing neuromuscular blocking agent that can be used to study the mechanism of action of muscle relaxants .

HY-14895B

Fabomotizole di(hydrochloride) CM346 dihydrochloride	Others	Neurological Disease
Fabomotizole dihydrochloride is an anxiolytic agent. Fabomotizole dihydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

HY-106888

CS-722 Free base	Endogenous Metabolite	Neurological Disease
CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex . CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-17033

Rocuronium Org-9426	Others	Neurological Disease Cancer
Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

HY-B0353

Chlormezanone	GABA Receptor	Neurological Disease
Chlormezanone resembles benzodiazepine. The action of Chlormezanone is similar to benzodiazepine-type agents. Chlormezanone is used as an anxiolytic and a muscle relaxant.

HY-A0258A

Metubine Metocurine iodide; Dimethylchondrocurarine iodide	Others	Neurological Disease
Metubine (Metocurine iodide) is a non-depolarizing muscle relaxant. Metubine has neuromuscular blocking activities .

HY-167650

Fletazepam	GABA Receptor	Neurological Disease
Fletazepam is a benzodiazepine derivative with sedative, anxiolytic and muscle relaxant effects. Fletazepam can be utilized in neurological research .

HY-14895

Fabomotizole CM346	Others	Neurological Disease
Fabomotizole (CM346) is an anxiolytic agent. Fabomotizole produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

HY-14895A

Fabomotizole hydrochloride CM346 hydrochloride	Others	Neurological Disease
Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic agent. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

HY-14657

Dantrolene sodium Maximum Cited Publications 8 Publications Verification F 440	Calcium Channel	Metabolic Disease
Dantrolene sodium salt is a calcium channel protein inhibitor that inhibits the release of calcium ions from the sarcoplasm. Dantrolene sodium salt hydrate is a skeletal muscle relaxant.

HY-128469

Inaperisone	GABA Receptor	Neurological Disease
Inaperisone is a centrally acting muscle relaxant. Inaperisone can inhibit the micturition reflex by acting indirectly on GABAB receptors in the brainstem .

HY-B1283R

Mephenesin (Standard)	iGluR	Neurological Disease
Mephenesin (Standard) is the analytical standard of Mephenesin. This product is intended for research and analytical applications. Mephenesin is an NMDA receptor antagonist and Mephenesin is a central muscle relaxant.

HY-B0740S

Cyclobenzaprine-d3 hydrochloride MK130-d₃ (hydrochloride)	5-HT Receptor	Neurological Disease
Cyclobenzaprine-d₃ (hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride. Cyclobenzaprine hydrochloride (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant.

HY-B1343R

Pridinol mesylate (Standard)	Cholinesterase (ChE)	Neurological Disease
Pridinol (mesylate) (Standard) is the analytical standard of Pridinol (mesylate). This product is intended for research and analytical applications. Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-127147

Fazadinium bromide AH 8165 bromide	Others	Others
Fazadinium bromide (AH 8165 bromide) is a neuromuscular blocking agent, that can prevent the muscle contraction. Fazadinium bromide can be used as a muscle relaxant during anesthesia .

HY-B0262S

Methocarbamol D5	Sodium Channel	Metabolic Disease
Methocarbamol-d₅ is deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel[1].

HY-121966

Riparin Riparin III	Others	Cancer
Riparin is a nonspecific smooth muscle relaxant. Riparin inhibits CaCl2-induced contractions in a reversible and non-competitive manner and can be used in spasmolytic studies .

HY-W016221

6-Hydroxy Chlorzoxazone	Drug Metabolite	Inflammation/Immunology
6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort .

HY-B1462S1

Chlorzoxazone-13C	Cytochrome P450	Inflammation/Immunology
Chlorzoxazone- ¹³C is the ¹³C labeled Chlorzoxazone[1]. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[2].

HY-B0353R

Chlormezanone (Standard)	GABA Receptor	Neurological Disease
Chlormezanone (Standard) is the analytical standard of Chlormezanone. This product is intended for research and analytical applications. Chlormezanone resembles benzodiazepine. The action of Chlormezanone is similar to benzodiazepine-type agents. Chlormezanone is used as an anxiolytic and a muscle relaxant.

HY-14895R

Fabomotizole (Standard)	Others	Neurological Disease
Fabomotizole (Standard) is the analytical standard of Fabomotizole. This product is intended for research and analytical applications. Fabomotizole (CM346) is an anxiolytic agent. Fabomotizole produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

HY-17440

Rocuronium Bromide 2 Publications Verification ORG 9426 Bromide	nAChR	Neurological Disease Cancer
Rocuronium Bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation.

HY-117162

S 1432	Others	Neurological Disease
S 1432 is a central nervous system depressant with anticonvulsant and muscle relaxant effects. S 1432 significantly reduces acetylcholine levels in the striatum, making it potentially valuable for research in the development of psychotropic drugs .

HY-127004

Silperisone hydrochloride RGH-5002	Sodium Channel	Others
Silperisone hydrochloride is an organosilicone compound similar to tolperisone that has centrally acting muscle relaxant properties. Silperisone (hydrochloride) is a sodium channel protein type 2 alpha channel blocker that blocks sodium and calcium channels in cells, reduces muscle cell excitability and contraction, reduces peripheral tone, and acts as a muscle relaxant and peripheral vascular dilator. Silperisone (hydrochloride) is used to study recurrent painful myoclonus due to spinal cord injury, abnormal hypertonia due to cerebrovascular disease, myotonia symptoms, pyramidal tonia syndrome, multiple sclerosis myospasm, and myelitis .

HY-106415

Terflavoxate	Calcium Channel	Neurological Disease
Terflavoxate is a flavone derivative with spasmolytic properties. Terflavoxate has Ca ²⁺-antagonistic effect is mainly responsible for Terflavoxate smooth muscle relaxant properties. Terflavoxate has the potential for overactive detrusor research .

HY-B0118A

Vecuronium bromide ORG NC 45	nAChR	Neurological Disease Cancer
Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .

HY-N2005

Cycleanine	Calcium Channel Apoptosis	Cardiovascular Disease Inflammation/Immunology Cancer
Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway .

HY-B0499A

Otilonium bromide 2 Publications Verification Octylonium bromide; SP63	mAChR	Neurological Disease
Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant which can interfere with the mobilization of calcium in intestinal smooth muscle, OB can be used for research of irritable bowel syndrome .

HY-113920A

Azumolene EU4093 free base	Calcium Channel	Metabolic Disease
Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research .

HY-N0301

Thiocolchicoside	GABA Receptor	Neurological Disease Inflammation/Immunology
Thiocolchicoside is a competitive γ-aminobutyric acid type A (GAB_AA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .

HY-B1700A

Mivacurium dichloride	nAChR	Neurological Disease
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-B1139

Tolperisone hydrochloride 1 Publications Verification	Apoptosis	Neurological Disease
Tolperisone hydrochloride is a centrally acting muscle relaxant studied in neurological disorders causing pathological rhabdomyosclerosis (pyramidal tract injury, multiple sclerosis, myelopathy, encephalomyelitis), spastic paralysis, and other muscle dystonia-related Encephalopathy. Tolperisone hydrochloride also has antiviral activity .

HY-124047

RX 67668	Cholinesterase (ChE)	Neurological Disease
RX 67668 is a potent cholinesterase inhibitor with an IC₅₀ of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue .

HY-126175

Neostigmine iodide	Endogenous Metabolite	Neurological Disease
Neostigmine iodide is a reversible acetylcholinesterase inhibitor with muscle tone-enhancing activity. Neostigmine iodide is primarily used to improve muscle function in patients with myasthenia gravis. Neostigmine iodide is also used in routine anesthesia to reverse the effects of nondepolarizing muscle relaxants such as rocuronium .

HY-107944

Chlorphenesin carbamate Maolate; U 19646	Others	Neurological Disease
Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W052144

(±) Anabasine 2 Publications Verification	Alkaloids Piperidine Alkaloids Structural Classification Other disease Classification of Application Fields Source classification Disease markers Other Diseases Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±) Anabasine is a biphasic muscle relaxant.

HY-N2005

Cycleanine	Alkaloids Structural Classification Classification of Application Fields Source classification Plants Cissampelos pareira Menispermaceae Inflammation/Immunology Disease Research Fields Alkaloid Dimers	Calcium Channel Apoptosis
Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway .

HY-N4323

14-Deoxyandrographolide	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-106888

CS-722 Free base	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex . CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-N4323R

14-Deoxyandrographolide (Standard)	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide (Standard) is the analytical standard of 14-Deoxyandrographolide. 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

Cat. No.	Product Name	Chemical Structure

HY-B0262S1

Methocarbamol-d3
Methocarbamol-d₃ is the deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3].

HY-B1462S

Chlorzoxazone-d3
Chlorzoxazone-d₃ is the deuterium labeled Chlorzoxazone. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans.

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-W052144S

(±) Anabasine-d4 dihydrochloride
(±) Anabasine-d₄ (dihydrochloride) is deuterium labeled (±) Anabasine. (±) Anabasine is a biphasic muscle relaxant.

HY-B0740S

Cyclobenzaprine-d3 hydrochloride
Cyclobenzaprine-d₃ (hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride. Cyclobenzaprine hydrochloride (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant.

HY-B0262S

Methocarbamol D5
Methocarbamol-d₅ is deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel[1].

HY-B1462S1

Chlorzoxazone-13C
Chlorzoxazone- ¹³C is the ¹³C labeled Chlorzoxazone[1]. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[2].

HY-B1139S

Tolperisone-d10 hydrochloride

Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

HY-B0262S2

Methocarbamol-13C,d3
Methocarbamol- ¹³C,d₃ is the ¹³C- and deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3].

HY-B1901S

Eperisone-d10 hydrochloride

Eperisone-d₁₀ (hydrochloride) is the deuterium labeled Eperisone hydrochloride. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3].

HY-B0678S

Metaxalone-d3

Metaxalone-d₃ is the deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

HY-B0678S1

Metaxalone-d6

Metaxalone-d₆ is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

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