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Results for "

sea

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Arp2/3 Complex (2) Bacterial (7) Bcl-2 Family (1) Cholinesterase (ChE) (2) Endogenous Metabolite (3) Fluorescent Dye (1) Fungal (4) GnRH Receptor (2) HDAC (1) HIV (1) HSV (1) Isotope-Labeled Compounds (1) Lipoxygenase (1) Mitochondrial Metabolism (1) Na+/Ca2+ Exchanger (1) Parasite (7) Phosphatase (1) Potassium Channel (1) Small Interfering RNA (siRNA) (1) Sodium Channel (6)
By Research Areas:	Cancer (13) Cardiovascular Disease (4) Endocrinology (3) Infection (17) Inflammation/Immunology (7) Metabolic Disease (2) Neurological Disease (13)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) mRNA (1) siRNAs (1)

Inhibitors & Agonists

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Isotope-Labeled Compounds

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15515

SEA0400 Maximum Cited Publications 17 Publications Verification	Na+/Ca2+ Exchanger	Cardiovascular Disease
SEA0400 is a novel and selective inhibitor of the Na ⁺-Ca ²⁺ exchanger (NCX), inhibiting Na ⁺-dependent Ca ²⁺ uptake in cultured neurons, astrocytes, and microglia with IC₅₀s of from 5 to 33 nM.

HY-N12705A

Thermohexamine hydrochloride	Others	Others
Thermohexamine hydrochloride is a polyamine that can be isolated from sea urchin .

HY-P4898A

Anthopleurin-A TFA	Sodium Channel	Cardiovascular Disease
Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone .

HY-127170

3-Hydroxycoumarin	Lipoxygenase	Others
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-RS12601

SEA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SEA Human Pre-designed siRNA Set A contains three designed siRNAs for SEA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SEA Human Pre-designed siRNA Set A SEA Human Pre-designed siRNA Set A

HY-P10431

Hc-CATH sea snake cathelicidin	Bacterial	Infection Inflammation/Immunology
Hc-CATH (Sea snake cathelicidin) is an antibacterial peptide with broad-spectrum. Hc-CATH inhibits Shigella dysenteriae and Klebsiella pneumoniae with MIC of 0.16 mM-20.67 mM. Hc-CATH exhibits anti-inflammatory efficacy .

HY-N8195

Quercetin 3-O-sophoroside-7-O-rhamnoside	Others	Others
Quercetin 3-O-sophoroside-7-O-rhamnoside is a flavonoid found in sea buckthorn berries .

HY-126594

Echinoside B	Fungal	Infection
Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites .

HY-P4898

Anthopleurin-A	Sodium Channel	Cardiovascular Disease
Anthopleurin-A is a soidum channel toxin. Anthopleurin-A is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A can be isolated from the sea anemone .

HY-124550

Sarcophine (+)-Sarcophine	Endogenous Metabolite	Neurological Disease
Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC₅₀ value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum .

HY-N2225

Isorhamnetin-3-O-sophoroside-7-O-rhamnoside	Others	Infection
Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippophaë rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-119332

3-Keto petromyzonol	Others	Endocrinology
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-N7747

Sceptrin dihydrochloride	Others	Infection
Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .

HY-129562

Cucumechinoside D	Others	Others
Cucumechinoside D is a potent bioactive compound, which is found in the sea cucumber Cucumaria echinata .

HY-P0245

Speract	Mitochondrial Metabolism	Metabolic Disease
Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.

HY-N7237

Stichloroside B1	Fungal	Infection
Stichloroside B1 is a class of antifungal triterpenoid oligosaccharide isolated from the sea cucumber Stichopus chloronotus (BRANDT) .

HY-P1808

LGnRH-III, lamprey	GnRH Receptor	Cancer
LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities .

HY-N3162

Obtucarbamate B	Others	Others
Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .

HY-130047

Bivittoside A	Others	Cancer
Bivittoside A is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal properties and potential for antitumor applications.

HY-130072

Bivittoside B	Others	Cancer
Bivittoside B is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal and potential antitumor activities.

HY-N12389

Quellenin	Fungal	Infection
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

HY-N10262

Piliformic acid	Endogenous Metabolite	Others
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

HY-N7059

Lactobionic acid	Bacterial	Infection
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-127042

6,7-Epoxy-latrunculin A 6,7-Epoxy-LAT-A	Arp2/3 Complex	Others
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects .

HY-W014566

4-Nitro-3-(trifluoromethyl)phenol 3-(Trifluoromethyl)-4-Nitrophenol; TFM	Others	Infection
4-Nitro-3-(trifluoromethyl)phenol (TFM) is a piscicide. It is toxic to sea lamprey (P. marinus) with LC₅₀ values ranging from 1.97 to 2.11 and 2.05 to 2.21 mg/L for sac and swim-up fry, respectively, 1.6 to 2.45 mg/L for juveniles, and 1.6 to 1.63 mg/L for adults. It is also toxic to juvenile lake sturgeon (A. fulvescens) less than 100 mm in size but not to a variety of other fish species. 4-Nitro-3-(trifluoromethyl)phenol (TFM) (50 μM) uncouples oxidative phosphorylation by 22 and 28% in isolated sea lamprey and rainbow trout (O. mykiss) liver, respectively. 4-Nitro-3-(trifluoromethyl)phenol (TFM) has been used as lampricides in the control of larval sea lamprey populations.

HY-123063

Petromyzonol 5α-Petromyzonol; 5α-PZ	Others	Others
Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant .

HY-B1207

Urethane 2 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-N4225

Aaptamine	Adrenergic Receptor	Endocrinology Cancer
Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner .

HY-118925

Holothurin A	Bcl-2 Family HDAC Phosphatase	Cancer
Holothurin A is a potent inhibitor against BCL2, HDAC1 and PTPN2 with an anticancer activity, which is derived from sea cucumber Holothuria scabra. Holothurin A plays an essential role in the process of apoptosis, cell cycle and suppressing tumor .

HY-N7234

Sarasinoside C1	Others	Others
Sarasinoside C1 is a 30-norlanostane saponin isolated from the sea sponge Melophlus sarasinorum collected from Kimbe Bay, Papua New Guinea. Sarasinoside C1 has potential roles in marine ecology and pharmacological applications .

HY-117044

12(R)-HEPE	Endogenous Metabolite	Metabolic Disease
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.1 The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE.

HY-W065835

2-Bromoaldisine	HIV	Infection
2-Bromoaldisine is a pyrrole alkaloid that can be isolated from the Red Sea: marine sponge Stylissa carter. 2-Bromoaldisine inhibits HIV-1 vector infection. 2-Bromoaldisine inhibits Raf/MEK/MAPK pathway .

HY-B1207S

Urethane-d5 Ethyl carbamate-d₅; Carbamic acid ethyl ester-d₅; Ethylurethane-d₅	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-B1207R

Urethane (Standard)	Bacterial Parasite	Infection Neurological Disease Cancer
Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-P1346

APETx2	Sodium Channel	Neurological Disease Inflammation/Immunology
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-P10564

Pardaxin P 4	Bacterial	Infection
Pardaxin P 4 is an antimicrobial peptide found in the secretions of Red Sea Moses sole. Pardaxin P 4 acts as a biomembrane perforator that can interact with phospholipid bilayers of different compositions and induce cytotoxicity and pore formation. Pardaxin P 4 can be used in the research of antimicrobial drugs .

HY-P1346A

APETx2 TFA	Sodium Channel	Neurological Disease Inflammation/Immunology
APETx2 TFA, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-165100

1,3-Dipalmitoleoyl glycerol DG(16:1/0:0/16:1); 1,3-Dipalmitolein	Others	Others
1,3-Dipalmitoleoyl glycerol (DG(16:1/0:0/16:1)) is a compound isolated from sea cucumber viscera, which has α-glucosidase inhibitory activity and has different degrees of inhibitory effects on α-glucosidase from different sources.

HY-137566

Cucumarioside H	Others	Cancer
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

HY-114899

Azamethiphos	Cholinesterase (ChE) Parasite	Neurological Disease
Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

HY-114899S

Azamethiphos-d6	Isotope-Labeled Compounds	Neurological Disease
Azamethiphos-d₆ is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

HY-114899R

Azamethiphos (Standard)	Cholinesterase (ChE) Parasite	Neurological Disease
Azamethiphos (Standard) is the analytical standard of Azamethiphos. This product is intended for research and analytical applications. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

HY-D0914

Fast Green FCF FD&C Green No. 3; Food green 3; C.I. 42053	Fluorescent Dye	Others
Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF is carcinogenic and acts as a presynaptic locus by inhibiting the release of neurotransmitters in the nervous system .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-P1604

ATX-II	Sodium Channel	Inflammation/Immunology
ATX-II is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na ⁺

HY-W717530

Retene 7-Isopropyl-1-methylphenanthrene	Others	Others
Retene is widely present in modern and ancient sediments, and can be extracted from fir forest soils, humus coal, continental petroleum source rocks, and deep-sea sediments. Retene can be toxic when exposed to light, and this light-induced toxicity can have lethal and sublethal effects on aquatic organisms. Retene can be used as a model compound to study the interaction between environmental pollutants and ultraviolet rays .

HY-P1604A

ATX-II TFA	Sodium Channel	Inflammation/Immunology
ATX-II TFA is a specific Na ⁺ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II TFA causes delayed inactivation of the Na ⁺

HY-16929

Latrunculin A 5+ Cited Publications LAT-A	Arp2/3 Complex	Cancer
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N12705A

Thermohexamine hydrochloride	Structural Classification Natural Products Animals Source classification	Others
Thermohexamine hydrochloride is a polyamine that can be isolated from sea urchin .

HY-127170

3-Hydroxycoumarin	Structural Classification other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Lipoxygenase
3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage .

HY-N8195

Quercetin 3-O-sophoroside-7-O-rhamnoside	Flavonols Flavonoids Classification of Application Fields Elaeagnaceae Source classification Hippophaë rhamnoides Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Quercetin 3-O-sophoroside-7-O-rhamnoside is a flavonoid found in sea buckthorn berries .

HY-126594

Echinoside B	Infection Structural Classification Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Disease Research Fields Saccharides Monosaccharides	Fungal
Echinoside B is a antifungal oligoglycosides isolated from Sea Cucumber Actinopyga echinites .

HY-124550

Sarcophine (+)-Sarcophine	Structural Classification Natural Products Neurological Disease Classification of Application Fields Animals Source classification Marine natural products Other marine organisms Disease Research Fields	Endogenous Metabolite
Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC₅₀ value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum .

HY-N2225

Isorhamnetin-3-O-sophoroside-7-O-rhamnoside	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Elaeagnaceae Source classification Hippophaë rhamnoides Phenols Polyphenols Plants Disease Research Fields	Others
Isorhamnetin-3-O-sophoroside-7-O-rhamnoside, the major flavonol glycoside, is isolated from sea buckthorn (Hippophaë rhamnoides). Isorhamnetin-3-O-sophoroside-7-O-rhamnoside has the algicidal activity against the growth of the harmful microalgae .

HY-119332

3-Keto petromyzonol	Classification of Application Fields Animals Source classification Disease Research Fields Endocrinology Steroids	Others
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

HY-N7747

Sceptrin dihydrochloride	Structural Classification Natural Products Marine natural products Source classification Sponge	Others
Sceptrin dihydrochloride is a compound isolated from the sea sponge Agelas sceptrum that is an antimicrobial agent .

HY-129562

Cucumechinoside D	Other Terpenoids Structural Classification Animals Terpenoids Source classification	Others
Cucumechinoside D is a potent bioactive compound, which is found in the sea cucumber Cucumaria echinata .

HY-N7237

Stichloroside B1	Structural Classification Polysaccharides Animals Source classification Saccharides	Fungal
Stichloroside B1 is a class of antifungal triterpenoid oligosaccharide isolated from the sea cucumber Stichopus chloronotus (BRANDT) .

HY-N3162

Obtucarbamate B	Structural Classification Natural Products Animals Source classification	Others
Obtucarbamate B is a carbamate derivative, that can be isolated from the South China Sea gorgonian coral Melitodes squamata Nutting .

HY-130047

Bivittoside A	Structural Classification Polysaccharides Animals Source classification Saccharides	Others
Bivittoside A is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal properties and potential for antitumor applications.

HY-130072

Bivittoside B	Structural Classification Polysaccharides Animals Source classification Saccharides	Others
Bivittoside B is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal and potential antitumor activities.

HY-N12389

Quellenin	Structural Classification Monophenols Microorganisms Source classification Phenols	Fungal
Quellenin is an anti-saprolegnia compound. Quellenin can be isolated from deep-sea fungus Aspergillus sp. YK-76

HY-N10262

Piliformic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea .

HY-N7059

Lactobionic acid	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields Saccharides	Bacterial
Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .

HY-127042

6,7-Epoxy-latrunculin A 6,7-Epoxy-LAT-A	Structural Classification Natural Products Microorganisms Source classification	Arp2/3 Complex
6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects .

HY-123063

Petromyzonol 5α-Petromyzonol; 5α-PZ	Triterpenes Structural Classification Terpenoids Marine natural products Source classification Marine microorganism	Others
Petromyzonol (5α-Petromyzonol) is a tetrahydroxy stearol produced by the bile of sea lamprey larvae from the bile acid precursor acetylcholic acid. Petromyzonol sulfate acts as a pheromone and oviposition chemical attractant .

HY-B1207

Urethane 2 Publications Verification Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane	Infection Structural Classification Natural Products Microorganisms Neurological Disease Classification of Application Fields Source classification Disease Research Fields	Bacterial Parasite
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-N4225

Aaptamine	Alkaloids Classification of Application Fields Animals Source classification Marine natural products Quinoline Alkaloids Sponge Disease Research Fields Endocrinology	Adrenergic Receptor
Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner .

HY-118925

Holothurin A	Structural Classification Terpenoids Pentacyclic Triterpenoids	Bcl-2 Family HDAC Phosphatase
Holothurin A is a potent inhibitor against BCL2, HDAC1 and PTPN2 with an anticancer activity, which is derived from sea cucumber Holothuria scabra. Holothurin A plays an essential role in the process of apoptosis, cell cycle and suppressing tumor .

HY-W065835

2-Bromoaldisine	Structural Classification Alkaloids Pyrrole Alkaloids Marine natural products Source classification	HIV
2-Bromoaldisine is a pyrrole alkaloid that can be isolated from the Red Sea: marine sponge Stylissa carter. 2-Bromoaldisine inhibits HIV-1 vector infection. 2-Bromoaldisine inhibits Raf/MEK/MAPK pathway .

HY-B1207R

Urethane (Standard)	Structural Classification Natural Products Microorganisms Source classification	Bacterial Parasite
Urethane (Standard) is the analytical standard of Urethane. This product is intended for research and analytical applications. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .

HY-P1346

APETx2	Structural Classification Natural Products Animals Source classification	Sodium Channel
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible ASIC3 inhibitor, with an IC₅₀ of 63 nM. APETx2 directly inhibits the ASIC3 channel by acting at its external side. APETx2 could reverses acid‐induced and inflammatory pain .

HY-137566

Cucumarioside H	Triterpenes Structural Classification Animals Terpenoids Source classification	Others
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

HY-P99436

Anatumomab mafenatox ABR-214936	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Others
Anatumomab mafenatox (ABR-214936) is a 73 KDa recombinant protein to recognize the tumor-associated antigen 5T4, which is widely expressing in malignancy. Anatumomab mafenatox is between a modified form of SEA and a murine Fab. The main side effects of Anatumomab mafenatox are reported to include fever, low blood pressure, pain, nausea and drowsiness .

HY-N10177

Peniterphenyl A	Infection Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HSV
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-16929

Latrunculin A 5+ Cited Publications LAT-A	Structural Classification Macrolide Antibiotics Animals Classification of Application Fields Antibiotics Marine natural products Source classification Other Diseases Sponge Disease Research Anticancer Disease Research Fields	Arp2/3 Complex
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

HY-N7236

Pervicoside B	Triterpenes Structural Classification Animals Terpenoids Source classification	Parasite Fungal
Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases .

HY-115407

Cochliodone A	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cochliodone A is an active compound extracted from cultures of the deep-sea derived fungus Chaetomium sp. and has antibacterial and anticancer activity. Cochliodone A is toxic to a variety of bacteria, with MICs of 15.3 μg/mL (V. vulnificus), 32.7 μg/mL (V. rotiferianus), 15.9 μg/mL (S. aureus ATCC 43300), and 16.3 μg/mL (S . aureus CGMCC 1.12409). Cochliodone A also inhibits a variety of cancer cell lines, with IC₅₀s of 28.1 μM (A549), 20.7 μM (HeLa), and 23.2 μM (Hep G2) .

Cat. No.	Product Name	Chemical Structure

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-114899S

Azamethiphos-d6
Azamethiphos-d₆ is deuterated labeled Azamethiphos. Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Species:	Human (1) Staphylococcus aureus (2)
Tag:	His (3) Strep (1) Myc (1)
Source:	Sf9 insect cells (1) E. coli (2)


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