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Results for "

sedative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (15) Adenosine Receptor (1) Adrenergic Receptor (17) AMPK (1) Antibiotic (2) Apoptosis (6) Autophagy (5) Bacterial (4) Biochemical Assay Reagents (3) c-Fms (1) Calcium Channel (7) Cholinesterase (ChE) (4) Cytochrome P450 (5) Dopamine Receptor (9) Drug Derivative (6) Drug Metabolite (4) Endogenous Metabolite (5) Enterovirus (3) ERK (1) Fungal (4) GABA Receptor (28) Histamine Receptor (30) iGluR (1) Influenza Virus (1) Isotope-Labeled Compounds (6) Ligands for E3 Ligase (1) LOX-1 (1) mAChR (8) Melatonin Receptor (1) Molecular Glues (1) nAChR (1) NF-κB (2) OAT (1) Opioid Receptor (1) Oxytocin Receptor (1) PAK (1) Parasite (3) PKC (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (4) ROCK (1) Sigma Receptor (1) SOD (1) Sodium Channel (4) Vasopressin Receptor (1) VEGFR (2) Wnt (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (7) Endocrinology (19) Infection (8) Inflammation/Immunology (22) Metabolic Disease (5) Neurological Disease (106)
Oligonucleotides:	Preservatives (1)

134

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1673

Potassium bromide, 99%	Biochemical Assay Reagents	Neurological Disease
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology .

HY-B1316

Trimetozine	Bacterial Antibiotic	Neurological Disease
Trimetozine is an orally active *sedative*. Trimetozine has mild tranquilizing effects. Trimetozine can be used for the research of anxiety .

HY-121890

Etoxybamide	Others	Neurological Disease
Etoxybamide is a sedative. Etoxybamide has sedative and hypnotic effects .

HY-119404

Diproqualone (±)-Diproqualone	GABA Receptor	Neurological Disease Inflammation/Immunology
diproqualone is methaqualone analogous with sedative, anxiolytic, anti-inflammatory and analgesic properties .

HY-N8422

1(10)-Aristolen-2-one	Others	Neurological Disease
1(10)-Aristolen-2-one is an agent with sedative effect .

HY-A0220

Rescinnamine Reserpinine	Drug Derivative	Cardiovascular Disease Metabolic Disease
Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research .

HY-137951

Metizolam	Drug Derivative	Neurological Disease
Metizolam, a thienotriazolodiazepine, is the demethylated analogue of Etizolam. Metizolam exhibits psychomotor stabilizing, anxiolytic, sedative, myo-relaxant and amnestic effects .

HY-167650

Fletazepam	GABA Receptor	Neurological Disease
Fletazepam is a benzodiazepine derivative with sedative, anxiolytic and muscle relaxant effects. Fletazepam can be utilized in neurological research .

HY-U00051

Propiomazine	Histamine Receptor	Neurological Disease
Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia .

HY-U00051A

Propiomazine hydrochloride	Histamine Receptor
Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia .

HY-125508

CCD-3693	GABA Receptor	Neurological Disease
CCD-3693 is an orally active GABA receptor agonist. CCD-3693 has anxiolytic, anticonvulsant and sedative hypnotic activities and can be used in research related to neurological diseases .

HY-120474

Ro 23-0364	Drug Derivative	Neurological Disease
Ro 23-0364 is an oral active imidazobenzodiazepine agent with mixed benzodiazepine. Ro 23-0364 shows sedative and can be used for study of neurological disease .

HY-107323

Bentazepam QM 6008; Thiadipone; Tiadipone	GABA Receptor	Neurological Disease
Bentazepam (Thiadipone) is a compound with short-action anxiolytic effect. Bentazepam shows anticonvulsant and sedative properties. Bentazepam can be used for the research of depressive disorder and anxiety .

HY-138014

Cinazepam	GABA Receptor	Neurological Disease
Cinazepam is a partial GABA_A receptor agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders .

HY-B1733

Phenyltoloxamine Bistrimin; Histionex	Histamine Receptor Sigma Receptor Cytochrome P450	Neurological Disease Inflammation/Immunology
Phenyltoloxamine (Bistrimin) is an antihistamine agent with sedative and analgesic effects. Phenyltoloxamine also has potent Sigma-1 receptor binding affinity (K_i: 160 nM) .

HY-W707158

Norfenfluramine hydrochloride (±)-Norfenfluramine hydrochloride	Drug Metabolite	Neurological Disease
Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration .

HY-107323A

Bentazepam hydrochloride QM 6008 hydrochloride; Thiadipone hydrochloride; Tiadipone hydrochloride	GABA Receptor	Neurological Disease
Bentazepam (QM 6008, Thiadipone) hydrocholide is a compound with short-action anxiolytic effect. Bentazepam hydrocholide shows anticonvulsant and sedative properties. Bentazepam hydrocholide can be used for the research of depressive disorder and anxiety .

HY-171253

Clotizolam	Platelet-activating Factor Receptor (PAFR)	Neurological Disease
Clotizolam is a thienobenzodiazepine derivative that has antagonistic activity against platelet-activating factor (PAF). Clotizolam possesses sedative, anxiolytic, anticonvulsant,and muscle relaxant effects .

HY-16505

Triclofos sodium	Endogenous Metabolite	Neurological Disease
Triclofos sodium is a drug used to suppress insomnia and for sedation and has sedative activity. Triclofos sodium is used in children for sedation during painless medical procedures, particularly in children with neurocognitive disorders. Triclofos sodium has similar physiological and pharmacological properties to chloral and therefore can be used as a substitute when necessary. The safety and efficacy of Triclofos sodium have been demonstrated in pediatric populations with high rates of neurocognitive disorders .

HY-17034B

Medetomidine hydrochloride MPV785	Adrenergic Receptor	Neurological Disease Endocrinology
Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (K_i: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels .

HY-17034

Medetomidine	Adrenergic Receptor	Neurological Disease Endocrinology
Medetomidine is an orally active α2-adrenoceptor agonist (K_i: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels .

HY-N8290

Lactupicrin Lactucopicrin	LOX-1 NF-κB Cholinesterase (ChE) Parasite	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC₅₀ of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone .

HY-153584

MRK-898	GABA Receptor	Neurological Disease
MRK-898 is an orally active GABA(A) receptor modulator. MRK-898 binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with K_i values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively. However, α1-containing GABA(A) receptors are identified as the "sedative" and α2- and/or α3-containing receptors as the "anxiolytic" subtype(s) .

HY-B1229

Isovaleramide 3-Methylbutanamide	GABA Receptor	Neurological Disease
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant that modulates central nervous system activity. Isovaleramide has anticonvulsant, anxiolytic, sedative, and sleep aid activities. Isovaleramide is promising for research of ethylene glycol (EG) poisoning-induced acute kidney injury and epilepsy .

HY-B0781

Promethazine hydrochloride 1 Publications Verification	Histamine Receptor mAChR Adrenergic Receptor	Neurological Disease Endocrinology
Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. Promethazine hydrochloride is a potent H1 receptor antagonist and a mAChR antagonist. It also has a certain affinity for 5-HT2A and 5-HT2C receptors .

HY-N11706

β-Cedrene (+)-β-Cedrene	Fungal	Infection Inflammation/Immunology
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-B0781R

Promethazine (hydrochloride) (Standard)	Histamine Receptor mAChR Adrenergic Receptor	Neurological Disease Endocrinology
Promethazine (hydrochloride) (Standard) is the analytical standard of Promethazine (hydrochloride). This product is intended for research and analytical applications. Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. Promethazine hydrochloride is a potent H1 receptor antagonist and a mAChR antagonist. It also has a certain affinity for 5-HT2A and 5-HT2C receptors .

HY-12706

Spiroxatrine R 5188	Adrenergic Receptor 5-HT Receptor	Neurological Disease Inflammation/Immunology
Spiroxatrine (R 5188) is a selective, dual antagonist of 5-HT1α and α2-adrenergic, with the K_i values of 3.94, 224000, 118.5 nM for 5-HT1α, 5-HT1β and 5-HT2, respectively. Spiroxatrine (R 5188) has a sedative effect .

HY-W050162

(E)-3,4,5-Trimethoxycinnamic acid TMCA	GABA Receptor 5-HT Receptor	Neurological Disease
(E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABA_A/BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT_2C and 5-HT_1A receptor, with IC₅₀ values of 2.5 and 7.6 μM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy .

HY-B1375

Pyrithyldione	c-Fms	Neurological Disease
Pyrithyldione is a sedative-hypnotic agent that induces agranulocytosis .

HY-B1594

Carbromal Adalin; Adisomnol; Bromacetocarbamide	Others	Neurological Disease
Carbromal (Adalin; Adisomnol) is a sedative with centrally depressant effects .

HY-118538

Noreximide	Endogenous Metabolite	Neurological Disease
Noreximide is a sedative, and can be used for psychiatric disease research .

HY-171028

3-Hydroxy desalkylflurazepam	GABA Receptor	Neurological Disease
3-Hydroxy desalkylflurazepam is a benzodiazepine with potential sedative and anxiolytic effects .

HY-119461

Capuride	Drug Derivative	Neurological Disease
Capuride is an orally active sedative agent. Capuride has anticonvulsant activity .

HY-14939

Vapitadine	Histamine Receptor	Inflammation/Immunology
Vapitadine is a non-sedative antihistamine compound that alleviates itching associated with atopic dermatitis.

HY-129105A

Chlormethiazole (edisylate)	GABA Receptor	Neurological Disease
Chlormethiazole (edisylate) is a sedative-hypnotic with active allosteric modulatory activity at GABAA receptors .

HY-138104

SL-164	Drug Derivative	Neurological Disease
SL-164 is a quinazolinone. SL-164 has sedative properties .

HY-167658

Tuclazepam KC 1956	GABA Receptor	Neurological Disease
Tuclazepam (KC 1956) is a derivative of benzodiazepines that has anti-anxiety and sedative effects .

HY-B0971

Pheniramine maleate Prophenpyridamine maleate; Tripoton maleate; Pheniramine maleate	Histamine Receptor Apoptosis	Inflammation/Immunology Endocrinology
Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0971A

Pheniramine Prophenpyridamine; Tripoton; Pheniramine solution	Histamine Receptor Apoptosis	Inflammation/Immunology Cancer
Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0950A

Mefexamide hydrochloride	Others	Neurological Disease
Mefexamide hydrochloride is a particular psychostimulant that is capable of reversing the psychodepressant effects induced by diazepam and benzodiazepine sedatives .

HY-117699

Fluanisone	Biochemical Assay Reagents	Neurological Disease
Fluanisone has potent sedative effect in vivo. Fluanisone can be used to study schizophrenia .

HY-B0950

Mefexamide	Dopamine Receptor	Neurological Disease
Mefexamide hydrochloride is a particular psychostimulant that is capable of reversing the psychodepressant effects induced by diazepam and benzodiazepine sedatives .

HY-135735A

Levomedetomidine hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Levomedetomidine hydrochloride is an isomer of Medetomidine (HY-17034), and a cardioprotective agent with sedative and analgesic effects .

HY-N13227

Valerian Extract	Others	Neurological Disease
Valerian Extract is a valerian extract. Valerian Extract has potential sedative and anxiolytic effects. .

HY-116195

L-Linalool (-)-Linalool	SOD	Neurological Disease
L-Linalool, a monoterpene with sedative and anxiolytic potential, has been used in Parkinson's disease research .

HY-W107263

4-Hydroxypentanoate sodium	Drug Metabolite	Neurological Disease
4-Hydroxypentanoate sodium, a sedative, is an active metabolite of gamma-Valerolactone (HY-W015938).

HY-121918

RU 41656	Others	Others
RU 41656 partially alleviated triazolam-induced memory impairment but did not counteract the sedative effects of this agent .

HY-163978

YGZ-331	Adenosine Receptor	Neurological Disease
YGZ-331 is a sedative with a calming effect. YGZ-331 is a derivative of the adenosine nucleoside NGBA, which can increase GABA levels. YGZ-331 exerts a sedative-hypnotic effect by activating A1R and A2aR, and inhibiting CaMKII phosphorylation (pCaMKII) levels. YGZ-331 can reduce the spontaneous motor activity of mice .

HY-W181871

Piperidione	Drug Derivative	Others
Piperidione is a cough agent .

Cat. No.	Product Name	Type

HY-Y1673

Potassium bromide, 99%	Buffer Reagents
Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8290

Lactupicrin Lactucopicrin	Structural Classification Monophenols Terpenoids Genista quadriflora Munby Sesquiterpenes Source classification Phenols Plants Compositae	LOX-1 NF-κB Cholinesterase (ChE) Parasite
Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC₅₀ of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone .

HY-B1229

Isovaleramide 3-Methylbutanamide	Structural Classification Natural Products other families Source classification Plants	GABA Receptor
Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant that modulates central nervous system activity. Isovaleramide has anticonvulsant, anxiolytic, sedative, and sleep aid activities. Isovaleramide is promising for research of ethylene glycol (EG) poisoning-induced acute kidney injury and epilepsy .

HY-116195

L-Linalool (-)-Linalool	Structural Classification Natural Products Cupressaceae Source classification Plants Chamaecyparis formosensis Matsum.	SOD
L-Linalool, a monoterpene with sedative and anxiolytic potential, has been used in Parkinson's disease research .

HY-Y0121

Ethyl cinnamate	Structural Classification Kaempferia galanga L. Microorganisms Classification of Application Fields Source classification Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields Zingiberaceae	Parasite VEGFR Apoptosis
Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC₅₀ values of 0.30 mM and 0.38 mM in rat aorta .

HY-N8422

1(10)-Aristolen-2-one	Labiatae Sesquiterpenes Source classification Prostanthera rotundifolia R.Br. Plants	Others
1(10)-Aristolen-2-one is an agent with sedative effect .

HY-A0220

Rescinnamine Reserpinine	Apocynaceae Alkaloids Piperidine Alkaloids Rauvolfia serpentina other families Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Plants Disease Research Fields Indole Alkaloids	Drug Derivative
Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research .

HY-N11706

β-Cedrene (+)-β-Cedrene	Centaurea kotschyi (Boiss.) Hayek Structural Classification Natural Products Source classification Plants Compositae	Fungal
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-N13227

Valerian Extract	Neurological Disease Classification of Application Fields Source classification Rubiaceae Plants Disease Research Fields	Others
Valerian Extract is a valerian extract. Valerian Extract has potential sedative and anxiolytic effects. .

HY-N8763

Ciwujianoside E Guaianin A	Structural Classification Polysaccharides Ketones, Aldehydes, Acids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside E is a triterpene saponin that can be isolated from Acanthopanax senticosus. Ciwujianoside E can be used in study sedative-hypnotic drug .

HY-Y0121R

Ethyl cinnamate (Standard)	Structural Classification Kaempferia galanga L. Microorganisms Source classification Other Phenylpropanoids Phenylpropanoids Plants Zingiberaceae	Parasite VEGFR Apoptosis
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC₅₀ values of 0.30 mM and 0.38 mM in rat aorta .

HY-B0163

Detomidine	Classification of Application Fields Disease Research Fields Endocrinology	Adrenergic Receptor
Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects .

HY-121118

Coronaridine 1 Publications Verification	Apocynaceae Alkaloids Source classification Tabernaemontana divaricata (Linnaeus) R. Brown ex Roemer & Schultes Plants Indole Alkaloids	Wnt
Coronaridine, an iboga type alkaloid, inhibits the wnt signaling pathway by decreasing β-catenin expression .

HY-116195R

L-Linalool (Standard)	Structural Classification Natural Products Cupressaceae Source classification Plants Chamaecyparis formosensis Matsum.	Others
L-Linalool (Standard) is the analytical standard of L-Linalool. This product is intended for research and analytical applications. L-Linalool, a monoterpene with sedative and anxiolytic potential, has been used in Parkinson's disease research .

HY-N2059

Santalol	Structural Classification other families Classification of Application Fields Santalum album Linn. Terpenoids Sesquiterpenes Source classification Plants Disease Research Fields Santalaceae Cancer	Apoptosis
Santalol is a mixture of α and β-isomer santalol. α-Santalol is found in sandalwood oil. α-Santalol is a promising anti-cancer agent against cancers such as oral, breast, prostate and skin cancer. Santalol has sedative activity .

HY-N8303

Gardenin A	Structural Classification Flavonoids Flavones Source classification Rutaceae Plants Citrus reticulata Blanco	ERK PAK
Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. Gardenin A also has sedative, anxiolytic, antidepressant, and anticonvulsant effects .

HY-N1919

Ajmalicine 1 Publications Verification Raubasine	Structural Classification Iridoids Classification of Application Fields Terpenoids Source classification Rosaceae Plants Disease Research Fields Endocrinology Rosa multifoloraThunb	Adrenergic Receptor Cholinesterase (ChE)
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α₁-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC₅₀ of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity .

HY-N1919A

Ajmalicine hydrochloride Raubasine hydrochloride	Alkaloids Source classification Rosaceae Plants Rosa multifoloraThunb	Adrenergic Receptor Cholinesterase (ChE)
Ajmalicine (Raubasine) hydrochloride is a potent adrenolytic agent which preferentially blocks α₁-adrenoceptor. Ajmalicine hydrochloride is an reversible but non-competitive nicotine receptor full inhibitor, with an IC₅₀ of 72.3 μM. Ajmalicine hydrochloride also can be used as anti-hypertensive, and serpentine, with sedative activity .

HY-N8290R

Lactupicrin (Standard)	Structural Classification Monophenols Terpenoids Genista quadriflora Munby Sesquiterpenes Source classification Phenols Plants Compositae	Autophagy NF-κB AMPK
Lactupicrin (Standard) is the analytical standard of Lactupicrin. This product is intended for research and analytical applications. Lactupicrin (Lactucopicrin) exhibits analgesic, sedative, antimalarial activities and atheroprotective effect. Lactupicrin inhibits acetylcholinesterase (AChE) with an IC₅₀ of 150.3 μM. Lactupicrin is an orally active characteristic bitter sesquiterpene lactone .

HY-N2081

Skimmianine 2 Publications Verification	Alkaloids Structural Classification Classification of Application Fields Source classification Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Inflammation/Immunology Disease Research Fields	Others
Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity .

HY-N2081R

Skimmianine (Standard)	Alkaloids Structural Classification Source classification Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort.	Others
Skimmianine (Standard) is the analytical standard of Skimmianine. This product is intended for research and analytical applications. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity .

HY-N12786

1,3-Dihydroxy-2-methoxyxanthone	Structural Classification Xanthones Source classification Polygalaceae Phenols Plants Polygala caudata Rehder & E. H. Wilson	Others
1,3-Dihydroxy-2-methoxyxanthone is a xanthone and can be isolated from Polygala caudata .

HY-N1919R

Ajmalicine (Standard)	Structural Classification Iridoids Terpenoids Source classification Rosaceae Plants Rosa multifoloraThunb	Adrenergic Receptor Cholinesterase (ChE)
Ajmalicine (Standard) is the analytical standard of Ajmalicine. This product is intended for research and analytical applications. Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity .

HY-N7814R

2-Hydroxypalmitic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
Pheniramine (maleate) (Standard) is the analytical standard of Pheniramine (maleate). This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-W011683R

2'-Deoxyadenosine monohydrate (Standard)	Natural Products Microorganisms Source classification	Endogenous Metabolite
Pheniramine (Standard) is the analytical standard of Pheniramine. This product is intended for research and analytical applications. Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

Cat. No.	Product Name	Chemical Structure

HY-B0725S

Doxepin D3 Hydrochloride
Doxepin-d₃ (hydrochloride) is a deuterium labeled Doxepin Hydrochloride. Doxepin hydrochloride is an orally active tricyclic antidepressant. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2].

HY-U00051AS

Propiomazine-d6 hydrochloride
Propiomazine-d₆ (hydrochloride) is deuterium labeled Propiomazine (hydrochloride). Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia .

HY-U00051AS1

(R)-Propiomazine-d6 hydrochloride
(R)-Propiomazine-d₆ (hydrochloride) is deuterium labeled Propiomazine (hydrochloride). Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia .

HY-U00051AS2

(S)-Propiomazine-d6 hydrochloride
(S)-Propiomazine-d₆ (hydrochloride) is deuterium labeled Propiomazine (hydrochloride). Propiomazine hydrochloride is an orally active antihistamine agent with sedative effects. Propiomazine hydrochloride can be used in the research of insomnia .

HY-B1296S1

Promethazine-d4
Promethazine-d4 is a deuterated-labeled promethazine (HY-B0781). Promethazine is an orally active H1 receptor and mAChR antagonist with antihistamine (H1), sedative, antiemetic, anticholinergic, and anti-motion sickness properties .

HY-17034BS1

Medetomidine-13C,d3 hydrochloride
Medetomidine-13C,d3 (hydrochloride) is a deuterated labeled Medetomidine (hydrochloride) . Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist (K_i: 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels .

HY-B0781S1

Promethazine-d3 hydrochloride

Promethazine-d₃ (hydrochloride) is deuterium labeled Promethazine (hydrochloride). Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. Promethazine hydrochloride is a potent H1 receptor antagonist and a mAChR antagonist. It also has a certain affinity for 5-HT2A and 5-HT2C receptors .

Cat. No.	Product Name		Classification

HY-W089856

Chlorobutanol hemihydrate		Preservatives
Chlorobutanol hemihydrate is an antimicrobial agent with oral activity, also possessing preservative effects. Chlorobutanol hemihydrate exhibits resistance to a variety of Gram-positive and Gram-negative bacteria, as well as several fungal spores and fungi, and is widely used in the food and cosmetics industries .

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