2. Immunology/Inflammation
  3. Interleukin Related
  4. Elsilimomab

Elsilimomab  (Synonyms: B-E8; Anti-IL-6 MAB B-E8; Anti-Human IL6 Recombinant Antibody)

Cat. No.: HY-P99287 Purity: 95.00%
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Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a KD of 22 pM and an IC50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA).

For research use only. We do not sell to patients.

CAS No. : 468715-71-1

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Based on 1 publication(s) in Google Scholar

Elsilimomab Related Antibodies

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Description

Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a KD of 22 pM and an IC50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA)[1][2][3].

Isotype

IgG1-nd
Species

Mouse

IC50 & Target

IL-6

1.4 nM (IC50)

In Vitro

Elsilimomab specifically inhibits IL-6 but not LIF (leukemia inhibitory factor)-induced cell growth[2].
Elsilimomab (20 μg/mL) neutralizes human IL-6[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Elsilimomab Related Antibodies

Cell Viability Assay[2]

Cell Line: Murine B9 cells
Concentration: 20 μg/mL
Incubation Time: 3 days
Result: B9 cells were stimulated with human IL-6, which was effectively neutralized by antibody Elsilimomab.
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Elsilimomab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG1-nd
Purity & Documentation
References
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Elsilimomab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elsilimomab468715-71-1B-E8 Anti-IL-6 MAB B-E8 Anti-Human IL6 Recombinant AntibodyInterleukin RelatedILMurine B9 cellsmonoclonal antibodymultiple myelomarenal cell carcinomarheumatoid arthritisInhibitorinhibitorinhibit

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