2. Gene
  3. Fap - fibroblast activation protein, alpha Gene

Fap - fibroblast activation protein, alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 192203 | Gene type: protein coding

About Fap

Summary

Predicted to enable several functions, including Integrin binding activity; peptidase activity; and protein homodimerization activity. Predicted to be involved in several processes, including melanocyte apoptotic process; melanocyte proliferation; and negative regulation of cell proliferation involved in contact inhibition. Predicted to be located in several cellular components, including basal part of cell; cell surface; and lamellipodium. Predicted to be part of peptidase complex. Predicted to be active in plasma membrane. Orthologous to human FAP (fibroblast activation protein alpha). [provided by Alliance of Genome Resources, Apr 2022]

Fap Products(1)

mRNA Protein Name
NM_138850.1 NP_620205.1 prolyl endopeptidase FAP
Protein Preferred Names Protein Names

prolyl endopeptidase FAP

seprase

Recombinant Fap Proteins

Cat. No. Product Name Accession Purity
HY-P78622 FAP Protein, Rat (HEK293, His) Q8R492-1 (L26-D761) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P3392 Zilganersen / Phase 3
HY-137331 FAPI-46 98.57% Phase 2
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99269 Sibrotuzumab ≥95.0% Phase 2
Pre-clinical Phase
Bioactive Molecules (42)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101801 Ac-Gly-BoroPro ≥98.0% Unkown
HY-147057 Rofapitide tetraxetan 99.54% Unkown
HY-128643 FAPI-4 98.42% Unkown
HY-145983 Suc-Gly-Pro-AMC 99.16% Unkown
HY-153552A NH2-UAMC1110 TFA Inhibitor 99.89% Unkown
HY-100684 UAMC-1110 Inhibitor 99.58% Unkown
HY-147173 FAPI-74 99.84% Unkown
HY-145938 OncoFAP 99.77% Unkown
HY-P10131 3BP-3940 99.96% Unkown
HY-47979A FAP-IN-2 TFA Inhibitor 99.92% Unkown
HY-47979 FAP-IN-2 Inhibitor 99.82% Unkown
HY-136641 NOTA-FAPI Inhibitor 99.26% Unkown
HY-164725 FAPI-mFS Inhibitor 99.78% Unkown
HY-164316 FT-FAPI-12_9 99.07% Unkown
HY-164364A DOTAGA.(SA.FAPi)2 TFA Inhibitor 96.81% Unkown
HY-139401 FAPI-34 99.67% Unkown
HY-128642 FAPI-2 98.94% Unkown
HY-125366 ARI-3099 / Unkown
HY-P3441A 3BP-4089 TFA 99.64% Unkown
HY-161074 PNT6555 96.55% Unkown
HY-147057A Rofapitide tetraxetan acetate / Unkown
HY-D2363 DOTA.SA.FAPi TFA Inhibitor 99.26% Unkown
HY-P3392A Zilganersen sodium Inhibitor 91.43% Unkown
HY-164316A FT-FAPI-12_9 TFA 99.48% Unkown
HY-172317 AZD2389 Inhibitor / Unkown
HY-172137 FAPI-FUSCC-07 Ligand / Unkown
HY-D2281 FAP Ligand 2 / Unkown
HY-146180 FSDD0I / Unkown
HY-146182 FSDD3I / Unkown
HY-128642A FAPI-2 TFA 98.05% Unkown
HY-148361 Fluorogen binding modulator-1 / Unkown
HY-146181 FSDD1I / Unkown
HY-158326 FAP-IN-4 Inhibitor / Unkown
HY-149860 FAP-IN-1 Inhibitor / Unkown
HY-P3441 3BP-4089 / Unkown
HY-161262 SB03178 Inhibitor / Unkown
HY-103323 Fas C-Terminal Tripeptide Inhibitor / Unkown
HY-170779 DOTA-NI-FAPI-04 Inhibitor / Unkown
HY-153552 NH2-UAMC1110 Inhibitor / Unkown
HY-164364B DOTAGA.(SA.FAPi)2 analogue TFA Inhibitor / Unkown
HY-W668749 3BP-3580 Inhibitor / Unkown
HY-163079 AlF-PD-FAPI / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991087 RO7122290 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fap NCBI NCBI:2191
Macaca fascicularis Fap NCBI NCBI:102134935
Mus musculus Fap NCBI NCBI:14089