1. Gene
  2. TG - thyroglobulin Gene

TG - thyroglobulin Gene

Homo sapiens

Also known as TGN; AITD3

Gene ID: 7038 | Gene type: protein coding

About TG

Cytogenetic location: 8q24.22 Genomic coordinates (GRCh38): 8:132,866,958-133,134,899 (from NCBI)

This gene has 20 transcripts (splice variants), 217 orthologues, 13 paralogues and is associated with 3 phenotypes. Restricted expression toward thyroid (RPKM 4323.9).

Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]

TG Products(1)

mRNA Protein Name
NM_003235.5 NP_003226.4 thyroglobulin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IDA
IDA: Inferred from direct assay
8626858 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
18687776 GOA
Biological Process GO Annotation Evidence Reference Source
involved in thyroid gland development IEP
IEP: Inferred from expression pattern
15494458 GOA
involved in thyroid hormone generation IDA
IDA: Inferred from direct assay
32025030 GOA
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
8626858 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TG Protein Structure

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (39 - 92)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (96 - 160)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (308 - 358)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (605 - 658)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (662 - 726)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (1023 - 1067)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (1091 - 1137)

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (1159 - 1210)

Ephrin_rec_like

Ephrin_rec_like: Putative ephrin-receptor like (1465 - 1510)

COesterase

COesterase: Carboxylesterase family (2203 - 2718)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2768 a.a.
Protein Preferred Names Protein Names

thyroglobulin

Related Diseases

Diseases Alias
Thyroid Dyshormonogenesis 3

TDH3

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 3

Thyroid Hormonogenesis, Genetic Defect In, 3

Genetic Defect In Thyroid Hormonogenesis 3

Chdh3

Congenital Hypothyroidism Due To Dyshormonogenesis Type 3

Genetic Defect In Thyroid Hormonogenesis Type 3

Autoimmune Thyroid Disease 3

Autoimmune Thyroid Disease, Susceptibility To, 3

AITD3

Autoimmune Thyroid Disease, Susceptibility To 3

Thyroid Disease, Autoimmune, Susceptibility To, Type 3

Congenital Hypothyroidism

Cretinism

Neonatal Hypothyroidism

Ch

Cht

Congenital Myxedema

Myxedema, Congenital

Endemic Cretinism

Congenital Iodine-Deficiency Syndrome

Fetal Iodine Deficiency Syndrome

Congenital Iodine-Deficiency Hypothyroidism Nos

Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter

Goiter

Goitre

Hypothyroidism

Thyroid Diseases

Thyroid Disease

Thyroid Deficiency

Thyroid Insufficiency

Dysfunction Thyroid

Thyroid Dysfunction

Thyroiditis

Inflammation Of Thyroid

Thyroiditis Nos

Papillary Carcinoma

Carcinoma, Papillary

Carcinoma Papillary

Struma Ovarii
Hyperthyroidism

Overactive Thyroid

Nodular Goiter

Goiter, Nodular

Nodular Goitre

Goiter Nodular

Non-Toxic Nodular Goiter

Subacute Thyroiditis

Giant-Cell Thyroiditis

Granulomatous Thyroiditis

Subacute Granulomatous Thyroiditis

De Quervain'S Thyroiditis

Thyroiditis Subacute

Thyroiditis, Subacute

Pseudogranulomatous Thyroiditis

De Quervain Thyroiditis

Nonsuppurative Subacute Thyroiditis

Pseudotuberculous Thyroiditis

Nonsuppurative Thyroiditis Nos

Nontoxic Goiter

Goiter, Non-Toxic

Goitre, Non-Toxic

Nodule-Thyroid, Non Tox

Non-Toxic Goitre

Non-Toxic Simple Goitre

Goitre Nos

Goitre Struma

Enlarged Thyroid Gland

Thyromegaly

Thyroid Hypertrophy

Thyroid Gland Hypertrophy

Thyroid Hyperplasia

Thyroid Gland Hyperplasia

Swelling Of Thyroid Gland

Substernal Thyroid Mass

Substernal Goitre

Substernal Thyroid

Retrosternal Thyroid Struma

Sporadic Nodular Struma

Struma Of Thyroid

Retrosternal Goitre

Plunging Goitre

Nontoxic Nodular Goitre

Nodular Struma

Form Of Goitre

Hyperplastic Goitre

Hypertrophic Thyroid

Intrathoracic Goitre

Nodular Goitre

Graves' Disease

Graves Disease

Exophthalmic Goiter

Basedow'S Disease

Grave'S Disease

Basedow Disease

Toxic Diffuse Goiter

Graves' Hyperthyroidism

Parry Disease

Autoimmune Hyperthyroidism

Toxic Multinodular Goiter

Hashimoto Thyroiditis

Autoimmune Thyroiditis

Hashimoto Struma

Hashimoto'S Thyroiditis

Chronic Lymphocytic Thyroiditis

Lymphocytic Thyroiditis

Hashimoto Disease

Ht

Hashimoto'S Disease

Hashimoto'S Syndrome

Hypothyroidism, Autoimmune

Autoimmune Chronic Lymphocytic Thyroiditis

Chronic Lymphocytic Thyroiditides

Hashimoto Syndrome

Hashimotos Thyroiditis

Hashimoto Thyroiditis, Susceptibility To

Thyroiditis, Autoimmune

Lymphomatous Thyroiditis

Lymphoid Thyroiditis

Chronic Lymphadenoid Thyroiditis

Autoimmune Lymphocytic Chronic Thyroiditis

Goitre Lymphomatosa

Hashitoxicosis

Hashimoto Hypothyroidism

Lymphadenoid Goitre

Struma Lymphomatosa

Hyperthyroidism With Hashimoto Disease

Hashimoto Thyrotoxicosis

Thyrotoxicosis Due To Hashimoto Thyroiditis

Struma Lymphomatosis

Lymphadenoid Struma

Follicular Adenoma

Follicular Adenoma Of The Thyroid Gland

Thyroid Follicular Adenoma

Adenoma Follicular

Follicular Thyroid Adenoma

Thyroid Gland Follicular Adenoma

Toxic Diffuse Goiter
Plummer'S Disease

Toxic Nodular Goiter

Plummer Disease

Goiter Toxic Nodular

Multinodular Goiter
Endemic Goiter

Iodine-Deficiency-Related Endemic Goitre

Simple Goitre

Goiter, Endemic

Euthyroid Goiter

Thyroid Crisis

Thyrotoxic Crisis

Thyroid Storm

Thyrotoxic Storm

Myxedema
Papillary Thyroid Microcarcinoma
Graves Ophthalmopathy

Graves Orbitopathy

Thyroid Associated Ophthalmopathy

Thyroid Eye Disease

Thyroid-Associated Ophthalmopathy

Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre

Pendred Syndrome

Goiter-Deafness Syndrome

Deafness With Goiter

PDS

Thyroid Dyshormonogenesis 2b

Tdh2b

Autosomal Recessive Sensorineural Hearing Impairment And Goiter

Pendred'S Syndrome

Thyroid Hormonogenesis, Genetic Defect In, 2b

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b

Congenital Hypothyroidism Due To Dyshormonogenesis 2b

Genetic Defect In Thyroid Hormonogenesis 2b

Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter

Goiter-Hearing Loss Syndrome

Goitre-Deafness Syndrome

Goitre Deafness

Ovarian Germ Cell Teratoma

Germ Cell Teratoma Of Ovary

Ovarian Teratoma

Malignant Struma Ovarii

Struma Ovarii, Malignant

Papillary Follicular Thyroid Adenocarcinoma

Carcinoma, Papillary, Follicular

Thyroid Carcinoma

Thyroid Cancer

Malignant Neoplasm Of Thyroid

Thyroid Neoplasm

Mucoepidermoid Carcinoma

Mec

Salivary Gland Mucoepidermoid Carcinoma

C3772

Carcinoma Mucoepidermoid

Carcinoma, Mucoepidermoid

Thyroid Cancer, Nonmedullary, 2

Thyroid Carcinoma, Follicular

Follicular Thyroid Carcinoma

NMTC2

Thyroid Cancer, Follicular

Thyroid Carcinoma, Follicular, Somatic

Ftc

Thyroid Cancer, Non-Medullary, 2

Thyroid Follicular Carcinoma

Follicular Thyroid Cancer

Cancer, Thyroid, Nonmedullary, Type 2

Thyroid Gland Adenocarcinoma

Follicular Carcinoma Of Unspecified Site

Moderately Differentiated Follicular Carcinoma Of Thyroid Gland

Pure Follicle Carcinoma Of Thyroid Gland

Pure Follicle Follicular Carcinoma Of Unspecified Site

Pure Follicular Carcinoma Of Thyroid Gland

Trabecular Follicular Carcinoma Of Thyroid Gland

Trabecular Follicular Carcinoma Of Unspecified Site

Well Differentiated Follicular Carcinoma Of Unspecified Site

Well Differentiated Follicular Carcinoma Of Thyroid Gland

Thyroid Lymphoma
Postsurgical Hypothyroidism

Postoperative Hypothyroidism

Post-Surgical Hypothyroidism

Benign Struma Ovarii
Suppurative Thyroiditis

Thyroiditis, Suppurative

Acute Suppurative Thyroiditis

Infectious Thyroiditis

Benign Teratoma

Dermoid Cyst

Cystic Dermoid Choristoma

Dermoid Choristoma

Mature Cystic Teratoma

Dermoid Tumour

Teratoma, Benign

Dermoid Cyst Of Ovary

Graves Disease 1

Thyrotoxicosis

Graves Disease, Susceptibility To, 1

GRD1

Grd

Hyperthyroidism, Autoimmune

Hyperthyroidism

Hyperactive Thyroid Gland

Overactive Thyroid

Toxic Diffuse Goitre

Toxic Primary Thyroid Hyperplasia

Stokes Disease

Thyrotoxicosis With Goitre

Thyrotoxicosis Struma

Graves Disease

Goitre With Hyperthyroidism

Basedow Disease

Exophthalmic Goitre

Exophthalmic Struma

Flajani Disease

Graves Disease With Exophthalmos

Hyperthyroid Goitre

Hyperthyroidism Struma

Thyroid Exophthalmos

Malignant Exophthalmos

Parry Disease

Toxic Diffuse Goitre With Exophthalmos

Toxic Goitre

Toxic Goitre Nos

Thyrotoxicosis Due To Uninodular Goitre

Toxic Thyroid Nodule

Toxic Uninodular Goitre

Uninodular Toxic Struma

Uninodular Toxic Struma With Hyperthyroidism

Thyrotoxicosis Due To Single Thyroid Nodule

Toxic Uninodular Goitre With Hyperthyroidism

Hyperthyroidism With Thyroid Nodule

Thyrotoxicosis With Toxic Uninodular Goitre

Uninodular Goitre In Hyperthyroidism

Uninodular Goitre In Thyrotoxicosis

Toxic Multinodular Goitre

Multinodular Goitre With Thyrotoxicosis

Thyrotoxicosis Nodular Goitre

Nodular Goitre With Thyrotoxicosis

Adenomatous Goitre With Hyperthyroidism

Multinodular Goitre With Hyperthyroidism

Nodular Goitre With Hyperthyroidism

Nodular Struma With Hyperthyroidism

Plummer Disease

Thyrotoxicosis Adenomatous Goitre

Thyrotoxicosis Adenomatous Struma

Toxic Adenomatous Goitre

Toxic Adenomatous Struma

Toxic Nodular Goitre Nos

Toxic Struma Nodosa

Toxic Nodular Struma

Fetal Adenoma

Microfollicular Adenoma

Thyroid Gland Anaplastic Carcinoma

Anaplastic Thyroid Carcinoma

Anaplastic Thyroid Cancer

Thyroid Cancer, Anaplastic

Thyroid Carcinoma, Anaplastic

Thyroid Carcinoma Anaplastic

Multicentric Papillary Thyroid Carcinoma

Multicentric Thyroid Gland Papillary Carcinoma

Thyroid Sarcoma

Sarcoma Of The Thyroid Gland

Thyroid Gland Sarcoma

Acute Thyroiditis

Infectious Thyroiditis

Subacute Lymphocytic Thyroiditis
Thyroid Gland Disease

Abnormality Of The Thyroid Gland

Thyroid Diseases

Exophthalmos

Proptosis

Endocrine Exophthalmos

Endocrine Exopthalmos

Thyroid Associated Opthalmopathies

Thyroid Hyalinizing Trabecular Adenoma

Plat

Atypical Follicular Adenoma
Thyroid Hormone Resistance, Generalized, Autosomal Dominant

Thyroid Hormone Resistance Syndrome

Thyroid Hormone Resistance

GRTHD

Gthr

Thyroid Hormone Unresponsiveness

Generalized Thyroid Hormone Resistance

Hyperthyroxinemia, Familial Euthyroid, Secondary To Pituitary And Peripheral Thyroid Hormones

Hyperthyroxinemia, Familial Euthyroid, Secondary To Pituitary And Peripheral Resistance To Thyroid Hormones

Refetoff Syndrome

Thyroid Hormone Responsiveness Defect

Familial Euthyroid Hyperthyroxinemia, Secondary To Pituitary And Peripheral Resistance To Thyroid Hormones

Thyroid Hormone Resistance, Generalized, Autosomal Recessive

Tall Cell Variant Papillary Carcinoma

Tall Cell Variant Thyroid Gland Papillary Carcinoma

Spindle Epithelial Tumor With Thymus-Like Differentiation Tumor

Settle Tumor

Settle Tumour

Spindle Epithelial Tumour With Thymus-Like Differentiation Tumour

Papillary Thymic Adenocarcinoma

Papillary Carcinoma Of The Thymus

Thyroid Carcinoma, Hurthle Cell

Hurthle Cell Carcinoma Of Thyroid

Hurthle Cell Thyroid Neoplasia

Hurthle Cell Thyroid Cancer

Follicular Thyroid Cancer, Hurthle Cell Type

Hurthle Cell Carcinoma Of The Thyroid

Thyroid Cancer, Hurthle Cell

Thyroid Cancer, Follicular, Hurthle Cell Type

Hurthle Cell Thyroid Carcinoma

HCTC

Hurthle Cell Carcinoma

Thyroid Hurthle Cell Carcinoma

Adenocarcinoma, Oxyphilic

Pernicious Anemia

Anemia, Pernicious

Anemia Pernicious

Pernicious Anaemia

Addison'S Anaemia

Biermer'S Anaemia

Biermer'S Anemia

Acquired Pernicious Anemia

Addison-Biermer Anemia

Addisonian Anemia

Biermer Anemia

Biermer'S Disease

Juvenile Onset Pernicious Anemia

Biermer Disease

Biermer-Addison Disease

Autoimmune Disease Of Endocrine System
Turner Syndrome

Monosomy X

Gonadal Dysgenesis Turner Type

Ullrich-Turner Syndrome

Bonnevie-Ullrich Syndrome

Karyotype 45, X

Genital Dwarfism, Turner Type

Gonadal Dysgenesis

45,X

Turner'S Syndrome

Gonadal Dysgenesis - Turner

Monosomy X Syndrome

Xo Syndrome

Genital Dwarfism

45, X Syndrome

Bonnevie-Ulrich Syndrome

Chromosome X Monosomy X

Schereshevkii Turner Syndrome

Turner Varny Syndrome

Ts

45,X Syndrome

45,X/46,Xx Syndrome

Turners Syndrome

Gonadal Dysgenesis, 45,X

X0 Syndrome

Multiple Endocrine Neoplasia

Men

Multiple Endocrine Adenomatosis

Multiple Endocrine Neoplasia Syndrome

Adenomatosis, Familial Endocrine

Endocrine Neoplasia, Multiple

Familial Endocrine Adenomatosis

Mea

Multiple Endocrine Neoplasms

Multiple Endocrine Neoplasia Type 1

Ovarian Germ Cell Cancer

Ovarian Germ Cell Tumor

Malignant Germ Cell Tumor Of Ovary

Germ Cell Neoplasm Of Ovary

Germ Cell Tumor Of Ovary

Mogct

Malignant Ovarian Germ Cell Tumor

Malignant Ovarian Germ Cell Neoplasm

Paraganglioma

Chemodectoma

Glomus Body Tumor

Paragangliomas

Carotid Body Paraganglioma

Extra-Adrenal Paraganglioma

Thyroid Angiosarcoma

Hemangiosarcoma Of The Thyroid

Trabecular Follicular Adenocarcinoma

Follicular Adenocarcinoma, Trabecular

Trabecular Follicular Carcinoma

Hypothyroidism, Congenital, Nongoitrous, 2

Thyroid Dysgenesis

CHNG2

Thyroid Hypoplasia

Thyroid Hemiagenesis

Thyroid Agenesis

Athyreotic Hypothyroidism

Rtsh

Thyrotropin Resistance

Hypothyroidism, Congenital, Due To Thyroid Dysgenesis Or Hypoplasia

Congenital Nongoitrous Hypothyroidism 2

Thyroid, Ectopic

Hypothyroidism, Congenital, Due To Thyroid Dysgenesis

Hypothyroidism, Athyreotic

Thyrotropin

Resistance To Thyrotropin

Congenital Hypothyroidism Due To Thyroid Dysgenesis Or Hypoplasia

Hypothyroidism, Congenital, Non-Goitrous, 2

Congenital Hypothyroidism Due To Thyroid Dysgenesis

Thyroid-Stimulating Hormone Resistance

Thyroid Ectopic

Ectopic Thyroid

Hypothyroidism, Congenital, Nongoitrous, 3

Thyroid Hormone Resistance Syndrome

Hypothyroidism, Congenital, Nongoitrous, 1

Substernal Goiter

Retrosternal Thyroid Goiter

Retrosternal Thyroid Goitre

Substernal Goitre

Goiter, Substernal

Thyroid Carcinoma, Familial Medullary

Medullary Thyroid Carcinoma

Familial Medullary Thyroid Carcinoma

MTC

Medullary Thyroid Cancer

Fmtc

Mtc1

Thyroid Cancer, Medullary

Thyroid Carcinoma, Medullary

Familial Mtc

Thyroid Carcinoma Medullary

Carcinoma, Thyroid, Medullary, Familial

Medullary Carcinoma Of Thyroid

Medullary Carcinoma With Amyloid Stroma, Unspecified Site

Medullary Carcinoma With Amyloid Stroma Of Thyroid

Thyroid Dyshormonogenesis 2a

TDH2A

Iodide Peroxidase Deficiency

Deficiency Of Iodide Peroxidase

Thyroid Peroxidase Deficiency

Genetic Defect In Thyroid Hormonogenesis 2a

Thyroid Hormonogenesis, Genetic Defect In, 2a

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2a

Chdh2a

Congenital Hypothyroidism Due To Dyshormonogenesis Type 2a

Thyroid Hormone Organification Defect 2

Tiod

Goiter, Multinodular 1, With Or Without Sertoli-Leydig Cell Tumors

Euthyroid Goiter

MNG1

Simple Goiter

Goiter Euthyroid

Goiter, Nontoxic, With Intrathyroidal Calcification

Multinodular Goiter, Adolescent

Familial Multinodular Goiter

Fmng

Familial Mng

Familial Multinodular Goiter Syndrome

Goiter Multinodular 1, With Or Without Sertoli-Leydig Cell Tumors

Goiter Nontoxic With Intrathyroidal Calcification

Goiter Non-Toxic With Intrathyroidal Calcification

Multinodular Goiter Adolescent

Goiter, Multinodular, Type 1, With/Without Sertoli-Leydig Cell Tumors

Endemic Goiter

Type 1 Diabetes Mellitus

Diabetes Mellitus, Insulin-Dependent

Diabetes Mellitus Type 1

IDDM

Type 1 Diabetes

Insulin-Dependent Diabetes Mellitus

T1D

Juvenile-Onset Diabetes

Jod

Diabetes Mellitus, Type 1

Diabetes Mellitus, Insulin-Dependent-1

Type I Diabetes Mellitus

Autoimmune Diabetes

Juvenile Diabetes

Juvenile-Onset Diabetes Mellitus

Diabetes, Insulin Dependent

Insulin-Dependent Diabetes Mellitus-1

Diabetes Mellitus Insulin-Dependent

Diabetes Autoimmune

Diabetes Mellitus, Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 1, Susceptibility To

Diabetes Type 1

Type I Diabetes

Diabetes, Autoimmune

T1dm - [Type 1 Diabetes Mellitus]

Iddm - [Insulin Dependent Diabetes Mellitus]

Type 1 Iddm

Juvenile Diabetes Mellitus Without Compications

Idiopathic Insulin-Dependent Diabetes Mellitus Without Complications

Juvenile-Onset Diabetes Mellitus Without Compications

Ketosis-Prone Diabetes Mellitus Without Compications

Juvenile-Onset-Type Diabetes Mellitus Without Compications

Breast Cystic Hypersecretory Carcinoma

Cystic Hypersecretory Carcinoma Of The Breast

Cystic Hypersecretory Duct Carcinoma Of The Breast

Middle Ear Carcinoma

Carcinoma Of Middle Ear

Carcinoma Of The Middle Ear

Thyroid Gland Follicular Carcinoma

Follicular Thyroid Carcinoma

Follicular Adenocarcinoma

Follicular Adenocarcinoma, Well Differentiated

Follicular Carcinoma

Thyroid Adenocarcinoma

Adenocarcinoma, Follicular

Cystic Teratoma

Dermoid Cyst

Benign Teratoma

Hypoadrenocorticism, Familial

Addison Disease

Primary Adrenocortical Insufficiency

Addison'S Disease

Adrenal Gland Hypofunction

Adrenal Hypoplasia

Adrenal Aplasia

Addison Disease, Chronic Adrenal Insufficiency

Primary Hypoadrenalism

Hypoadrenocorticism Familial

Autoimmune Addison Disease

Autoimmune Adrenalitis

Classic Addison Disease

Primary Addison Disease

Addisons Disease

Addison Disease, Susceptibility To

Autoimmune Primary Adrenal Insufficiency

Addison'S Disease Due To Autoimmunity

Chronic Urticaria

Urticaria Chronic

Chronic Spontaneous Urticaria

Chronic Ordinary Urticaria

Adenoma

Acinar Cell Adenoma

Adenomas

Acinic Cell Adenoma

Iodine Hypothyroidism

Iodine Deficiency Hypothyroidism

Thyroid Gland Hurthle Cell Carcinoma

Oncocytic Carcinoma Of The Thyroid

Thyroid Cancer, Hurthle Cell

Colloid Adenoma

Macrofollicular Adenoma

Mechanical Strabismus

Strabismus

Acquired Deformity Of Ocular Muscle

Nonencapsulated Sclerosing Carcinoma

Nonencapsulated Sclerosing Neoplasm

Papillary Carcinoma, Diffuse Sclerosing

Epithelial Malignant Thymoma

Squamoid Thymoma

Thymoma, Epithelial

Well Differentiated Thymic Carcinoma

Thymoma, Type B3

Thyroid Gland Medullary Carcinoma

Medullary Thyroid Carcinoma

Medullary Carcinoma Of The Thyroid Gland

Ultimobranchial Thyroid Tumor

Ultimobranchial Thyroid Tumour

Thyroid Cancer, Medullary

Celiac Disease 1

Celiac Disease

Coeliac Disease

Celiac Sprue

Celiac Disease, Susceptibility To

Gluten-Sensitive Enteropathy

Nontropical Sprue

Sprue

CELIAC1

Celiac Disease, Susceptibility To, 1

Celiac Sprue 1

Celiac Sprue, Susceptibility To, 1

Gluten-Sensitive Enteropathy 1

Gluten-Sensitive Enteropathy, Susceptibility To, 1

Idiopathic Steatorrhea

Cœliac Disease

Gluten Intolerance

Gluten-Induced Enteropathy

Gluten Enteropathy

Celiac Disease, Susceptibility To, Type 1

Childhood Celiac Disease

Coeliac Rickets

Gee Disease

Gee-Herter Disease

Heubner-Herter Disease

Idiopathic Steatorrhoea

Thaysen'S Disease

Herter Gee Syndrome

Diabetes Insipidus
Clear Cell Adenoma
Atrophic Glossitis

Atrophy Of Tongue Papillae

Glossitis, Hunter'S

Hunter'S Glossitis

Smooth Atrophic Tongue

Hunter Glossitis

Central Papillary Atrophy Of The Tongue

Cyclotropia
Thyrotoxic Exophthalmos
Neonatal Thyrotoxicosis
Hypothyroidism, Congenital, Nongoitrous, 4

Tsh Deficiency

CHNG4

Thyrotropin Deficiency, Isolated

Pituitary Cretinism

Congenital Nongoitrous Hypothyroidism 4

Isolated Thyrotropin Deficiency

Thyroid-Stimulating Hormone Deficiency

Hypothyroidism, Congenital, Nongoitrous 4

Thyroid-Stimulating Hormone, Deficiency Of

Isolated Thyroid-Stimulating Hormone Deficiency

Isolated Tsh Deficiency

Hypothyroidism, Congenital, Nongoitrous, Type 4

Secondary Hypothyroidism

Tsh - [Thyroid Stimulating Hormone] Deficiency

Euthyroid Sick Syndrome

Euthyroid Sick Syndromes

Sick-Euthyroid Syndrome

Ess - [Euthyroid Sick Syndrome]

Low-T3 Syndrome

Ntis - [Non-Thyroidal Illness Syndrome]

Tscitus - [Thyroid Allostasis In Critical Illness, Tumours, Uraemia And Starvation]

Dyshormonogenic Goiter

Dyshormonogenic Goitre

Vulvar Keratinizing Squamous Cell Carcinoma
Immature Teratoma Of Ovary

Malignant Teratoma Of Ovary

Ovarian Immature Teratoma

Ovarian Malignant Teratoma

Teratoma With Malignant Transformation Of Ovary

Ectopic Thymus
Type 1 Diabetes Mellitus 5

Diabetes Mellitus, Insulin-Dependent, 5

Latent Autoimmune Diabetes In Adults

IDDM5

Insulin-Dependent Diabetes Mellitus 5

T1D5

Lada

Type 1.5 Diabetes

Diabetes Mellitus, Insulin-Dependent, Type 5

Middle Ear Adenocarcinoma

Adenocarcinoma Of Middle Ear

Adenocarcinoma Of The Middle Ear

Adrenal Cortical Hypofunction

Adrenal Cortical Insufficiency

Corticoadrenal Insufficiency

Thyroid Hormone Resistance, Selective Pituitary

PRTH

Selective Pituitary Thyroid Hormone Resistance

Selective Pituitary Resistance To Thyroid Hormone

Familial Hyperthyroidism Due To Inappropriate Thyrotropin Secretion

Hyperthyroidism, Familial, Due To Inappropriate Thyrotropin Secretion

Pituitary Resistance To Thyroid Hormone

Hypothyroidism, Congenital, Nongoitrous, 1

Tsh Resistance

CHNG1

Hypothyroidism Due To Tsh Receptor Mutations

Thyrotropin Resistance

Thyroid-Stimulating Hormone

Rtsh

Hypothyroidism Due To Unresponsiveness To Thyrotropin

Congenital Nongoitrous Hypothyroidism 1

Thyroid-Stimulating Hormone, Resistance To

Hypothyroidism, Nonautoimmune

Hypothyroidism, Congenital, Due To Tsh Resistance

Hypothyroidism, Congenital, Non-Goitrous, 1

Congenital Hypothyroidism Due To Tsh Resistance

Non-Autoimmune Hypothyroidism

Thyroid-Stimulating Hormone Resistance

Hypothyroidism, Congenital, Nongoitrous, Type 1

Hypothyroidism, Congenital, Nongoitrous, 3

Thyroid Hormone Resistance Syndrome

Viral Hepatitis

Animal Viral Hepatitis

Hepatitis, Viral, Animal

Human Viral Hepatitis

Viral Hepatitis With Hepatic Coma

Horner'S Syndrome

Horner Syndrome

Bernard-Horner Syndrome

Oculosympathetic Palsy

Bernard Horner Syndrome

Cervical Sympathetic Paralysis

Von Passow Syndrome

Cervical Sympathetic Dystrophy

Thyroid Gland Mucoepidermoid Carcinoma

Mucoepidermoid Thyroid Carcinoma

Orbital Disease

Orbit

Orbital Diseases

Dendritic Cell Thymoma

Epithelioid Thymoma

Type B Thymoma

Ovarian Benign Neoplasm

Benign Ovarian Neoplasm

Autoimmune Disease

Autoimmune Diseases

Autoimmune Hypersensitivity Disease

Hypersensitivity Reaction Type Ii Disease

Type Ii Hypersensitivity Reaction Disease

Parathyroid Gland Disease

Parathyroid Diseases

Disease Of Parathyroid Glands

Parathyroid Disease

Chronic Spontaneous Urticaria

Chronic Idiopathic Urticaria

Mature Teratoma

Dermoid Cyst

Benign Teratoma

Heart Leiomyosarcoma

Leiomyosarcoma Of Heart

Cardiac Leiomyosarcoma

Pulmonary Aspergilloma
Chronic Orbital Inflammation

Chronic Inflammation Of Orbit

Mature Teratoma Of The Ovary
Isthmus Cancer
Orbital Plasma Cell Granuloma

Orbital Myositis

Orbital Pseudotumor

Pseudotumor Of Orbit

Plasma Cell Granuloma, Orbital

Autoimmune Gastritis
Autoimmune Polyendocrine Syndrome

Autoimmune Polyendocrinopathy

Autoimmune Polyglandular Failure

Autoimmune Polyglandular Syndrome

Polyendocrinopathies, Autoimmune

Lloyd'S Syndrome

Aps

Polyendocrinopathies Autoimmune

Polyendocrine Autoimmunity Syndrome

Lloyd Syndrome

Polyglandular Autoimmune Deficiency

Progressive Pluriglandular Insufficiency

Pluriglandular Autoimmune Atrophy

Pluriglandular Autoimmune Syndrome

Thyroid-Adrenocortical Insufficiency Syndrome

Parathyroid Adenoma

Adenoma Of Parathyroid

Adenoma Of The Parathyroid Gland

Parathyroid Gland Adenoma

Nasal Cavity Olfactory Neuroblastoma

Olfactory Neuroblastoma Of The Nasal Cavity

Papillary Adenocarcinoma

Infiltrating And Papillary Adenocarcinoma

Infiltrating Papillary Adenocarcinoma

Adenocarcinoma Papillary

Adenocarcinoma, Papillary

Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1

Vitiligo

VAMAS1

Slev1

Vtlg

Systemic Lupus Erythematosus, Vitiligo-Related

Vitiligo-Associated Multiple Autoimmune Disease 1

Systemic Lupus Erythematosus Vitiligo-Related

Lagophthalmos

Defective Lid Closure

Poor Closure Eyelids

Carotid Body Cancer

Cancer Of Carotid Body

Malignant Carotid Body Paraganglioma

Malignant Carotid Body Tumor

Malignant Neoplasm Of Carotid Body

Ovary Leiomyosarcoma

Leiomyosarcoma Of Ovary

Salivary Gland Disease

Salivary Gland Disorders

Salivary Gland Diseases

Non-Neoplastic Salivary Gland Disease

Non-Neoplastic Salivary Gland Disorder

Disorder Of Salivary Gland

Lesion Of Salivary Gland Nos

Adrenal Cortex Disease

Adrenal Cortex Diseases

Endocrine Organ Benign Neoplasm
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos

Ovarian Serous Cystadenofibroma
Immunodeficiency 58

IMD58

Severe Combined Immunodeficiency Due To Carmil2 Deficiency

Combined Immunodeficiency Due To Carmil2 Deficiency

Combined Immunodeficiency Due To Rltpr Deficiency

Ovarian Serous Adenofibroma
Diabetes Mellitus

Diabetes

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TG RGD RGD:3848
Canis familiaris TG VGNC VGNC:47306
Macaca mulatta TG VGNC VGNC:99476
Bos taurus TG VGNC VGNC:35798
Mus musculus TG MGD MGI:98733
Felis catus TG VGNC VGNC:66128
Macaca fascicularis TG NCBI NCBI:102121703
Susscrofa domestica TG NCBI
Others TG NCBI