CEP44 - centrosomal protein 44 Gene

Homo sapiens

Also known as PS1TP3; KIAA1712

Gene ID: 80817 | Gene type: protein coding

About CEP44

This gene has 10 transcripts (splice variants) and 195 orthologues. Ubiquitous expression in testis (RPKM 3.4), endometrium (RPKM 3.1) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in centriole replication and centriole-centriole cohesion. Located in centriole; centrosome; and spindle pole. [provided by Alliance of Genome Resources, Apr 2022]

CEP44 Products(2)

mRNA	Protein	Name
NM_001040157.3	NP_001035247.1	centrosomal protein of 44 kDa isoform a
NM_001145314.2	NP_001138786.1	centrosomal protein of 44 kDa isoform b

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IDA IDA: Inferred from direct assay	32060285	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in centriole replication	IDA IDA: Inferred from direct assay	32060285	GOA
involved in centriole-centriole cohesion	IMP IMP: Inferred from mutant phenotype	31974111	GOA
involved in centrosome cycle	IMP IMP: Inferred from mutant phenotype	31974111	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in centriole	IDA IDA: Inferred from direct assay	32060285	GOA
located in centrosome	IDA IDA: Inferred from direct assay	21399614	GOA
located in spindle pole	IDA IDA: Inferred from direct assay	21399614	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEP44 Protein Structure

CEP44

0
100
200
300
390 a.a.

Protein Preferred Names

Protein Names

centrosomal protein of 44 kDa

HBV PreS1-transactivated protein 3

CEP44 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CEP44	Q9C0F1	BEND7	Homo sapiens	Q8N7W2-2	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	CEP57L1	Homo sapiens	Q8IYX8-2	Y2H Array	25416956
Intra	CEP44	Q9C0F1	CEP57L1	Homo sapiens	Q8IYX8-2	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	CEP57L1	Homo sapiens	Q8IYX8-2	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	LRRFIP1	Homo sapiens	Q32MZ4-4	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	LRRFIP1	Homo sapiens	Q32MZ4-4	Y2H Array	25416956
Intra	CEP44	Q9C0F1	GNG11	Homo sapiens	Q53Y01	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	GNG11	Homo sapiens	Q53Y01	Y2H Array	25416956
Intra	CEP44	Q9C0F1	GNG11	Homo sapiens	Q53Y01	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	FAM74A4	Homo sapiens	Q5TZK3	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	FAM74A4	Homo sapiens	Q5TZK3	Y2H Array	25416956
Intra	CEP44	Q9C0F1	CCDC146	Homo sapiens	Q8IYE0-2	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	CCDC146	Homo sapiens	Q8IYE0-2	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	MGC24125	Homo sapiens	Q8NEQ2	Y2H Array	25416956
Intra	CEP44	Q9C0F1	MGC24125	Homo sapiens	Q8NEQ2	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	DHX57	Homo sapiens	Q6P158	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	DHX57	Homo sapiens	Q6P158	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	DHX57	Homo sapiens	Q6P158	Y2H Array	25416956
Intra	CEP44	Q9C0F1	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	32296183
Intra	CEP44	Q9C0F1	HAUS1	Homo sapiens	Q96CS2	BioID	26638075
Intra	CEP44	Q9C0F1	HAUS1	Homo sapiens	Q96CS2	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	DIP2A	Homo sapiens	Q14689	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	DIP2A	Homo sapiens	Q14689	Y2H Array	25416956
Intra	CEP44	Q9C0F1	CAB39	Homo sapiens	Q9Y376	Validated Y2H	32296183
Intra	CEP44	Q9C0F1	BYSL	Homo sapiens	Q13895	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	BYSL	Homo sapiens	Q13895	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	TXLNA	Homo sapiens	P40222	Y2H Array	25416956
Intra	CEP44	Q9C0F1	CDC23	Homo sapiens	Q9UJX2	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	CDC23	Homo sapiens	Q9UJX2	Y2H Array	25416956
Intra	CEP44	Q9C0F1	BLOC1S6	Homo sapiens	Q9UL45	Validated Y2H	32296183
Intra	CEP44	Q9C0F1	ING5	Homo sapiens	Q8WYH8	Y2H Array	25416956
Intra	CEP44	Q9C0F1	ING5	Homo sapiens	Q8WYH8	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	MLLT6	Homo sapiens	Q6P2C6	Y2H Array	25416956
Intra	CEP44	Q9C0F1	MLLT6	Homo sapiens	Q6P2C6	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	ERAL1	Homo sapiens	O75616	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	ERAL1	Homo sapiens	O75616	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	ERAL1	Homo sapiens	O75616	Y2H Array	25416956
Intra	CEP44	Q9C0F1	ZNF587	Homo sapiens	Q96SQ5	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	ZNF587	Homo sapiens	Q96SQ5	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	H2AP	Homo sapiens	O75409	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	H2AP	Homo sapiens	O75409	Y2H Array	25416956
Intra	CEP44	Q9C0F1	TCEA2	Homo sapiens	Q15560	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	TCEA2	Homo sapiens	Q15560	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	MAPK9	Homo sapiens	P45984	Y2H Array	25416956
Intra	CEP44	Q9C0F1	DCTN2	Homo sapiens	Q13561	BioID	26638075
Intra	CEP44	Q9C0F1	TRIM41	Homo sapiens	Q8WV44	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	TRIM41	Homo sapiens	Q8WV44	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	FXR2	Homo sapiens	P51116	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	FXR2	Homo sapiens	P51116	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	FXR2	Homo sapiens	P51116	Y2H Array	25416956
Intra	CEP44	Q9C0F1	ZNF417	Homo sapiens	Q8TAU3	Y2H	21516116
Intra	CEP44	Q9C0F1	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	CHIC2	Homo sapiens	Q9UKJ5	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	CHIC2	Homo sapiens	Q9UKJ5	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	CHIC2	Homo sapiens	Q9UKJ5	Y2H Array	25416956
Intra	CEP44	Q9C0F1	CBY2	Homo sapiens	Q8NA61	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	CBY2	Homo sapiens	Q8NA61	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	CBY2	Homo sapiens	Q8NA61	Y2H Pooling	16189514
Intra	CEP44	Q9C0F1	ABI3	Homo sapiens	Q9P2A4	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	ABI3	Homo sapiens	Q9P2A4	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	ABI3	Homo sapiens	Q9P2A4	Validated Y2H	32296183
Intra	CEP44	Q9C0F1	ABI3	Homo sapiens	Q9P2A4	Y2H Array	25416956
Intra	CEP44	Q9C0F1	PLEKHF2	Homo sapiens	Q9H8W4	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	25416956
Intra	CEP44	Q9C0F1	AQP1	Homo sapiens	P29972	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	AQP1	Homo sapiens	P29972	Y2H Array	25416956
Intra	CEP44	Q9C0F1	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	SCNM1	Homo sapiens	Q9BWG6	Y2H Array	25416956
Intra	CEP44	Q9C0F1	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	MRFAP1L1	Homo sapiens	Q96HT8	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	MRFAP1L1	Homo sapiens	Q96HT8	Y2H Array	25416956
Intra	CEP44	Q9C0F1	LMO1	Homo sapiens	P25800	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	LMO1	Homo sapiens	P25800	Validated Y2H	25416956
Intra	CEP44	Q9C0F1	LMO1	Homo sapiens	P25800	Y2H Array	25416956
Intra	CEP44	Q9C0F1	ZFYVE26	Homo sapiens	Q68DK2-5	Y2H Prey Pooling	25416956
Intra	CEP44	Q9C0F1	ZFYVE26	Homo sapiens	Q68DK2-5	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 29

RP29

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02516	CEP44 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CEP44	VGNC	VGNC:39129
Bos taurus	CEP44	VGNC	VGNC:27205
Macaca mulatta	CEP44	VGNC	VGNC:71134
Rattus norvegicus	CEP44	RGD	RGD:1308517
Mus musculus	CEP44	MGD	MGI:3525111
Felis catus	CEP44	VGNC	VGNC:60775

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