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  4. (R)-GSK 2830371

(R)-GSK 2830371 is the R-enantiomer of GSK 2830371 (HY-15832). GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM.

For research use only. We do not sell to patients.

(R)-GSK 2830371 Chemical Structure

(R)-GSK 2830371 Chemical Structure

CAS No. : 2743427-27-0

Size Price Stock Quantity
5 mg USD 216 In-stock
10 mg USD 306 In-stock
25 mg USD 585 In-stock
50 mg USD 972 In-stock
100 mg USD 1620 In-stock
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(R)-GSK 2830371 Related Antibodies

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Description

(R)-GSK 2830371 is the R-enantiomer of GSK 2830371 (HY-15832). GSK 2830371 is a highly selective Wip1 phosphatase inhibitor with IC50 of 6 nM[1].

Molecular Weight

461.02

Formula

C23H29ClN4O2S
CAS No.
SMILES

ClC1=CN=C(C)C(NCC2=CC=C(C(N[C@H](CC3CCCC3)C(NC4CC4)=O)=O)S2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (433.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1691 mL 10.8455 mL 21.6910 mL
5 mM 0.4338 mL 2.1691 mL 4.3382 mL
View the Complete Stock Solution Preparation Table

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1691 mL 10.8455 mL 21.6910 mL 54.2276 mL
5 mM 0.4338 mL 2.1691 mL 4.3382 mL 10.8455 mL
10 mM 0.2169 mL 1.0846 mL 2.1691 mL 5.4228 mL
15 mM 0.1446 mL 0.7230 mL 1.4461 mL 3.6152 mL
20 mM 0.1085 mL 0.5423 mL 1.0846 mL 2.7114 mL
25 mM 0.0868 mL 0.4338 mL 0.8676 mL 2.1691 mL
30 mM 0.0723 mL 0.3615 mL 0.7230 mL 1.8076 mL
40 mM 0.0542 mL 0.2711 mL 0.5423 mL 1.3557 mL
50 mM 0.0434 mL 0.2169 mL 0.4338 mL 1.0846 mL
60 mM 0.0362 mL 0.1808 mL 0.3615 mL 0.9038 mL
80 mM 0.0271 mL 0.1356 mL 0.2711 mL 0.6778 mL
100 mM 0.0217 mL 0.1085 mL 0.2169 mL 0.5423 mL
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(R)-GSK 2830371 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-GSK 28303712743427-27-0OthersInhibitorinhibitorinhibit

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