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FABP4/5-IN-5 (compound D9) is a potent inhibitor of FABP4 and FABP5,? with the IC50s of 4.68 μM and 10.72 μM, respectively.FABP4/5-IN-5 plays an important role in metabolism disorder like diabetes mellitus .
FABP4-IN-2 (Compd 10g) is a selective and orally active FABP4 inhibitor with the Ki values of 0.51 μM for FABP4, 33.01 μM for FABP3. FABP4-IN-2 can be used in the research of inflammation-related diseases .
FABP4-IN-3 (compound C3) is a highly selective FABP4 inhibitor (FABP4 Ki = 25 ± 3 a nM, FABP3 Ki = 15.03 μM) which exhibits a 601-fold selectivity over FABP3. FABP4-IN-3 also shows metabolic stability and potent cellular anti-inflammatory activity, making it promising to get involved in the research of metabolic disease, cardiac dysfunction and inflammation-related disease .
FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models .
FABP4/5-IN-4 (compound E1) is a potent inhibitor of FABP4 and FABP5, with the IC50s of 3.78 μM and 5.72 μM, respectively. FABP4/5-IN-4 plays an important role in metabolism disorder like diabetes mellitus .
FABP3 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP6 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP9 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP5 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP12 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP7 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP4 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP2 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP1 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABPs ligand 6 (MF6) is an FABP5 and FABP7 inhibitor with KD values of 874 nM and 20 nM, respectively. FABPs ligand 6 can be used for multiple sclerosis research .
a-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production .
Arachidonic acid-Biotin is a biotin-labeled Arachidonic acid (HY-109590) that can be used to detect complexes of arachidonic acid with protein binding partners such as fatty acid binding proteins (FABPs) .
ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties. ART26.12 effectively prevents and alleviates Oxaliplatin (HY-17371)-induced pain through lipid modulation and cannabinoid receptor activation .
SBFI-26 is a selective and competitive inhibitor of fatty acid binding proteins FABP5 and FABP7, with Kis of 0.9 µM and 0.4 µM for FABP5 and FABP7, respectively. SBFI-26 produces anti-nociceptive and anti-inflammatory effects .
BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
RO6806051 (compound12) is a potent dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with good selectivity and absorption, distribution, metabolism and excretion (eADME) properties .
ZLY28 is the first-in-class intestinal restricted and orally active FXR and FABP1 dual modulator. ZLY28 also is a novel anti-NASH agent. ZLY28 can be used for the research of nonalcoholic steatohepatitis (NASH) .
CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
ST-CY14 is an inhibitor for Nur77-PPARγ interaction with an EC50 of 3.15 μM, that binds to Nur77 (Kd=32 nM), blocks Nur77 from being ubiquitinated and degraded by PPARγ, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models .
CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
ST-CY14 is an inhibitor for Nur77-PPARγ interaction with an EC50 of 3.15 μM, that binds to Nur77 (Kd=32 nM), blocks Nur77 from being ubiquitinated and degraded by PPARγ, reduces fatty acid uptake and mitochondrial respiration, and inhibits the transcription of CD36 and FABP4. ST-CY14 inhibits the proliferation and migration of cancer cell MCF7 and MDA-MB-231. ST-CY14 inhibits tumor growth and bone metastasis in mouse models .
FABP5 acts as an intracellular carrier of long-chain fatty acids and related lipids and regulates ligand metabolism. It selectively delivers specific fatty acids from the cytoplasm to the nucleus, activating nuclear receptors including peroxisome proliferator-activated receptor delta, promoting proliferation and survival. FABP5 Protein, Human (His) is the recombinant human-derived FABP5 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP5 Protein, Human (His) is 134 a.a., with molecular weight of ~17 kDa.
FABP3 is a member of the fatty acid-binding protein (FABP) family and is thought to facilitate the intracellular transport of long-chain fatty acids and their acyl-CoA esters. As part of this family of proteins, FABP3 may play a crucial role in promoting cellular uptake and transport of fatty acids, supporting various metabolic processes within cells. FABP3 Protein, Mouse is the recombinant mouse-derived FABP3 protein, expressed by E. coli , with tag free. The total length of FABP3 Protein, Mouse is 133 a.a., with molecular weight of ~14.8 kDa.
FABP2, also known as I-FABP, is involved in the intracellular transport of long-chain fatty acids and their acyl-CoA esters, reflecting its potential role in various metabolic processes. In particular, FABP2 is thought to be involved in triglyceride-rich lipoprotein synthesis, suggesting its importance in lipid metabolism. FABP2/I-FABP Protein, Human (His) is the recombinant human-derived FABP2/I-FABP protein, expressed by E. coli , with N-6*His, C-6*His labeled tag. The total length of FABP2/I-FABP Protein, Human (His) is 132 a.a., with molecular weight of ~18 kDa.
FABP1 Protein, Human (His) is a Recombinant FABP1 Protein with a His-flag. FABP1 Protein is a cytoplasm protein and belongs to the calycin superfamily and FABP family.
FABP1/L-FABP Protein is crucial for lipoprotein-mediated cholesterol uptake in hepatocytes, specifically binding cholesterol, free fatty acids, coenzyme A derivatives, and bilirubin within the cytoplasm. It may also participate in intracellular lipid transport, sharing similarities with other proteins. FABP1/L-FABP Protein, Human (His, solution) is the recombinant human-derived FABP1/L-FABP protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP1/L-FABP Protein, Human (His, solution) is 127 a.a., with molecular weight of ~15.0 kDa.
FABP3 Protein, Human (His) is a recombinant FABP3 protein with a His-flag. FABP3 Protein is expressed in the skeletal muscle, heart, brain and brown adipose tissue.
The FABP4 protein binds hormone receptors, fatty acids, and transports them. It regulates thermogenesis, brown fat cell differentiation, and response to lithium ion. It is located in the cytoplasm and nucleus, and is expressed in adipose tissue, CNS, genitourinary system, gut, and heart. It shares orthology with human FABP4. Biased expression is seen in subcutaneous and genital fat pads. FABP4 Protein, Mouse (His) is the recombinant mouse-derived FABP4 protein, expressed by E. coli , with N-His labeled tag. The total length of FABP4 Protein, Mouse (His) is 131 a.a., with molecular weight of ~15.63 kDa.
FABP1/L-FABP Protein facilitates cholesterol uptake in hepatocytes via lipoproteins, binding cholesterol, free fatty acids, coenzyme A derivatives, bilirubin, and small molecules within the cytoplasm. It may also participate in intracellular lipid transport processes. FABP1/L-FABP Protein, Mouse (His) is the recombinant mouse-derived FABP1/L-FABP protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP1/L-FABP Protein, Mouse (His) is 127 a.a., with molecular weight of ~15 kDa.
FABP4 Protein, a member of the calycin superfamily, is classified within the fatty-acid binding protein (FABP) family. FABP4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FABP4 protein, expressed by HEK293, with C-His labeled tag. The total length of FABP4 Protein, Mouse (HEK293, His) is 132 a.a., with molecular weight of ~15 kDa.
FABP5 acts as an intracellular carrier of long-chain fatty acids and related lipids and regulates ligand metabolism. It selectively delivers specific fatty acids from the cytoplasm to the nucleus, activating nuclear receptors including peroxisome proliferator-activated receptor delta, promoting proliferation and survival. FABP5 Protein, Human is the recombinant human-derived FABP5 protein, expressed by E. coli , with tag free. The total length of FABP5 Protein, Human is 135 a.a., with molecular weight of ~15.2 kDa.
FABP12 Protein, Human is the recombinant human-derived FABP12, expressed by E. coli , with tag Free labeled tag. The total length of FABP12 Protein, Human is 140 a.a.,
FABP9 Protein, Human is the recombinant human-derived FABP9, expressed by E. coli , with tag Free labeled tag. The total length of FABP9 Protein, Human is 132 a.a.,
FABP7 Protein, Human expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms.
FABP5, also known as E-FABP, acts as an intracellular carrier of long-chain fatty acids and related lipids and regulates ligand metabolism.In addition to cytoplasmic transport, it selectively transports fatty acids to the nucleus, activates nuclear receptors, and delivers retinoic acid to promote proliferation.FABP5 Protein, Mouse (His) is the recombinant mouse-derived FABP5 protein, expressed by E.coli , with N-6*His labeled tag.
FABP7 Protein, Human (His) expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms.
FABP4 Protein, expressed mainly in adipocytes, crucially mediates lipid and retinoic acid transport. It binds long-chain fatty acids and retinoic acid, facilitating delivery to nuclear receptors. Functioning as a monomer and forming homodimers, FABP4 interacts with PPARG, contributing to its involvement in fatty acid metabolism and signaling pathways. FABP4 Protein, Human (His) is the recombinant human-derived FABP4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP4 Protein, Human (His) is 131 a.a., with molecular weight of ~15.0 kDa.
Gastrotropin/FABP6 is a fatty acid binding protein, or ileal bile acid binding protein (IBABP). FABP6 is a therapeutic target related to immune infiltration, and FABP6 inhibition inhibits cancer cell proliferation and migration. Gastrotropin/FABP6 Protein, Human (His) is the recombinant human-derived Gastrotropin/FABP6 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Gastrotropin/FABP6 Protein, Human (His) is 128 a.a., with molecular weight of ~15.0 kDa.
FABP4 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to FABP4. It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
FABP 1; FABP1; FABP1; FABPL; FABPL_HUMAN; Fatty Acid Binding Protein 1; Fatty acid binding protein 1 liver; Fatty Acid Binding Protein; Fatty acid-binding protein 1; Fatty acid-binding protein; Fatty acid-binding protein liver; L FABP; L-FABP; liver; Liver-type fatty acid-binding protein.
ELISA
Human
FABP1 Antibody (YA965) is a non-conjugated IgG1 antibody, targeting FABP1, with a predicted molecular weight of 14 kDa. FABP1 Antibody (YA965) can be used for ELISA experiment in human background.
FABP 1; FABP1; FABP1; FABPL; FABPL_HUMAN; Fatty Acid Binding Protein 1; Fatty acid binding protein 1 liver; Fatty Acid Binding Protein; Fatty acid-binding protein 1; Fatty acid-binding protein; Fatty acid-binding protein liver; L FABP; L-FABP; liver; Liver-type fatty acid-binding protein.
WB, IHC-F, IHC-P, ICC/IF
Mouse
FABP1 Antibody (YA967) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA967), targeting FABP1, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). FABP1 Antibody (YA967) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in mouse background.
FABP2 Antibody (YA2788) is a non-conjugated IgG antibody, targeting FABP2, with a predicted molecular weight of 15 kDa (observed band size: 15 kDa). FABP2 Antibody (YA2788) can be used for WB experiment in human, mouse, rat background.
422 protein; Cardiac Fatty Acid Binding Protein; FABP 11; FABP 3; FABP11; FABP3; FABPH_HUMAN; fatty acid binding protein 11; Fatty acid binding protein 3; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3
ELISA
Human
FABP3 Antibody (YA968) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA968), targeting FABP3. FABP3 Antibody (YA968) can be used for ELISA experiment in human background.
422 protein; Cardiac Fatty Acid Binding Protein; FABP 11; FABP 3; FABP11; FABP3; FABPH_HUMAN; fatty acid binding protein 11; Fatty acid binding protein 3; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3
ELISA
Human
FABP3 Antibody (YA969) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA969), targeting FABP3. FABP3 Antibody (YA969) can be used for ELISA experiment in human background.
422 protein; Cardiac Fatty Acid Binding Protein; FABP 11; FABP 3; FABP11; FABP3; FABPH_HUMAN; fatty acid binding protein 11; Fatty acid binding protein 3; Fatty acid binding protein 3 muscle and heart; Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor; Fatty acid binding protein 3 muscle; Fatty acid binding protein 3
WB, IHC-P
Human, Mouse, Rat
FABP3 Antibody (YA970) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA970), targeting FABP3, with a predicted molecular weight of 15 kDa (observed band size: 15 kDa). FABP3 Antibody (YA970) can be used for WB, IHC-P experiment in human, mouse, rat background.
FABP1; FABPL; Fatty acid-binding protein, liver; Fatty acid-binding protein 1; Liver-type fatty acid-binding protein (L-FABP)
IHC-P
Human
liver FABP Antibody (YA1268) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1268), targeting liver FABP. liver FABP Antibody (YA1268) can be used for IHC-P experiment in human background.
FABP3 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP6 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP9 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP5 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP12 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP7 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP4 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP2 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
FABP1 Human Pre-designed siRNA Set A contains three designed siRNAs for FABP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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