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Results for "

Plant metabolite

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Metabolite (4) Endogenous Metabolite (24) Antibiotic (2) Bacterial (4) COX (1) Cytochrome P450 (2) EGFR (1) Fungal (5) HSP (1) Interleukin Related (1) Isotope-Labeled Compounds (5) Lipoxygenase (1) NO Synthase (2) Parasite (1) Reactive Oxygen Species (2) Wnt (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (3) Endocrinology (1) Infection (12) Inflammation/Immunology (8) Metabolic Disease (10) Neurological Disease (10)

Inhibitors & Agonists

Screening Libraries

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Metabolite Endogenous Metabolite

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8879

Wilforol A (-)-Wilforol A	Others	Metabolic Disease
Wilforol A ((-)-Wilforol A), plant metabolite, is a pentacyclic triterpenoid. Wilforol A can be used for the research of various biochemical studies .

HY-N13295

Indole-3-lactate-O-β-D-glucopyranoside Ethyl α-(β-D-glucopyranosyloxy)-1H-indole-3-propanoate	Endogenous Metabolite	Others
Indole-3-lactate-O-β-D-glucopyranoside is an endogenous metabolite that acts as a plant growth regulator .

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-Hydroxyindole-3-carboxaldehyde	Others	Others
4-Hydroxy-1H-indole-3-carbaldehyde is a plant metabolite found in Capparis spinosa L.. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe .

HY-Y0694

2',4'-Dihydroxyacetophenone Resacetophenone; 1-(2,4-Dihydroxyphenyl)ethanone	Endogenous Metabolite	Others
2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'. 2',4'-Dihydroxyacetophenone involves in a practical CsHCO₃-mediated alkylation that efficiently provide 4-alkylated products with excellent regioselectivity, good isolated yields and a broad substrate scope. 2',4'-Dihydroxyacetophenone is a plant metabolite .

HY-111741

M700F048	Fungal	Infection
M700F048 is a major plant metabolite of fungicide Fluxapyroxad .

HY-125572

Gibberellin A7 GA7	Others	Others
Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells .

HY-N1099

Vellosimine (+)-Vellosimine; Alkaloid RB 19	Others	Others
Vellosimine ((+)-Vellosimine) is an indole alkaloid. Vellosimine acts as a plant metabolite .

HY-N10292

Chaetosemin J	Fungal Endogenous Metabolite	Infection
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .

HY-N3694

Deacetylnimbin Desacetyl nimbin	Others	Others
Deacetylnimbin is a limonoid isolated from Azadirachta indica. Deacetylnimbin can be used as a plant metabolite, a food repellent and as a growth regulator for insects such as S. litura, P. ricini and O. fscovittata .

HY-110406

13(S)-HPODE	EGFR Endogenous Metabolite	Metabolic Disease
13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.

HY-N0771

L-Isoleucine 3 Publications Verification	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .

HY-N3454

Isotaxiresinol	Others	Others
Isotaxiresinol is a lignan, which can be isolated from Taxus yunnanensis and has the function of plant metabolites .

HY-N10293

Monaschromone	Fungal Endogenous Metabolite	Infection
Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM .

HY-B1804S1

Tricaprilin-d50 Trioctanoin-d₅₀; Glyceryl trioctanoate-d₅₀	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-d₅₀ is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].

HY-B1804S2

Tricaprilin-d15 Trioctanoin-d₁₅; Glyceryl trioctanoate-d₁₅	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-d₁₅ is the deuterium labeled Tricaprilin. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite[1][2].

HY-121822

Agrocinopine	Others	Infection
Agrocinopine is a metabolite obtained from Agrobacterium-induced crown gall tumors in plants. It is composed of phosphorylated opines (such as agrocinopine A and B) and nitrogenous opines (such as nopaline). Agrocinopine can be transferred into plant cells via Ti plasmids and isolated from root nodules. Agrocinopine has potential roles in plant-microbe interactions and tumor development .

HY-N0771R

L-Isoleucine (Standard)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .

HY-W012999

Tiglic acid	Endogenous Metabolite	Others
Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite .

HY-N9502

Linalool oxide	Others	Neurological Disease
Linalool oxide is a secondary metabolite in elongating wheat plants with antinociceptive and anticonvulsant effects. Linalool oxide shows anxiolytic activity .

HY-N7061

Tropine	Others	Neurological Disease
Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-N2754

Sternbin Eriodictyol 7-methyl ether; 7-O-Methyleriodictyol	Others	Others
Sternbin is the detoxified metabolites from the rice flavanone phytoalexin Sakuranetin by Pyricularia oryzae. Sakuranetin is a flavanone phytoalexin associated with disease resistance in rice plants .

HY-Y1031

3-Ethoxy-3-oxopropanoic acid	Endogenous Metabolite	Metabolic Disease
3-Ethoxy-3-oxopropanoic acid is an endogenous metabolite. 3-Ethoxy-3-oxopropanoic acid promotes plant growth .

HY-Y1031A

3-Ethoxy-3-oxopropanoic acid potassium	Endogenous Metabolite	Metabolic Disease
3-Ethoxy-3-oxopropanoic acid potassium is an endogenous metabolite. 3-Ethoxy-3-oxopropanoic acid potassium promotes plant growth .

HY-125572R

Gibberellin A7 (Standard)	Others	Others
Gibberellin A7 (Standard) is the analytical standard of Gibberellin A7. This product is intended for research and analytical applications. Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells .

HY-75342

Methyl vanillate 2 Publications Verification	Wnt Reactive Oxygen Species Endogenous Metabolite	Inflammation/Immunology Cancer
Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-142063

Petasitenine Fukinotoxin	Endogenous Metabolite	Others
Petasitenine (Fukinotoxin) is a pyrrolizidine alkaloid that can be found in the plant Petasites japonicus, which is a carcinogenic metabolite of neopetasitenine. Petasitenine causes lactate dehydrogenase leakage, and exhibits hepatotoxicity .

HY-118614

β-Nicotyrine	Drug Metabolite	Neurological Disease
β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .

HY-N13014

Indole-3-acetyl β-D-glucopyranose	Others	Others
Indole-3-acetyl β-D-glucopyranose is a glucose esterified derivative of the plant hormone indole-3-acetic acid (IAA). Indole-3-acetyl β-D-glucopyranose is involved in regulating plant growth and can be used to study the metabolism and regulatory mechanisms of plant hormones .

HY-136560

6-Azathymine acid	Drug Metabolite	Others
6-Azathymine acid is a metabolite of Pymetrozine. Pymetrozine is active against plant-sucking insects, such as aphids and whiteflies in vegetables, cotton, field crops and fruits and affects the nervous regulation of feeding behavior .

HY-N7719

Oosporein	Endogenous Metabolite	Others
Oosporein is a red crystalline metabolite produced by a toxin-producing strain of Chaetomium trilaterale. Chaetomium trilaterale is isolated from moldy Peanuts. Oosporein inhibits plant growth and produces phytotoxic effects .

HY-N7378

N-Hydroxypipecolic acid 2 Publications Verification 1-Hydroxy-2-piperidinecarboxylic acid; NHP	Bacterial	Inflammation/Immunology
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection .

HY-N7378A

N-Hydroxypipecolic acid potassium 1-Hydroxy-2-piperidinecarboxylic acid potassium; NHP potassium	Bacterial	Inflammation/Immunology
N-Hydroxypipecolic acid potassium (1-Hydroxy-2-piperidinecarboxylic acid potassium), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid potassium accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid potassium induces SAR to bacterial and oomycete infection .

HY-B1804R

Tricaprilin (Standard)	Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Tricaprilin (Standard) is the analytical standard of Tricaprilin. This product is intended for research and analytical applications. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite .

HY-W342604

N-Acetylputrescine NAP	Endogenous Metabolite	Neurological Disease Cancer
N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis .

HY-N11528

Eugenitol 7-Noreugenitin	Others	Infection
Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .

HY-B1804S

Tricaprilin-13C3 Trioctanoin-¹³C₃; Glyceryl trioctanoate-¹³C₃	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite .

HY-N13021

2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid	Endogenous Metabolite	Others
2-(2-Hydroxy-5-methoxyphenoxy)-acrylic acid is a metabolite, which can be isolated from endophytic fungus Phoma macrostoma inhabiting the inner tissue of medicinal plant Glycyrrhiza glabra Linn .

HY-129548

Prumycin	Antibiotic	Infection
Prumycin is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .

HY-129548A

Prumycin di(hydrochloride)	Others	Infection
Prumycin dihydrochloride is an antifungal antibiotic with activity against cucumber powdery mildew. Prumycin dihydrochloride significantly inhibited the disease, whereas other metabolites such as bacillomycin D and surfactin did not. Prumycin dihydrochloride did not induce the expression of plant defense genes, indicating that its effects were not through plant defense responses. Observation of cucumber cotyledons treated with prumycin showed that it could inhibit spore germination of P. fusca .

HY-N11287

UDP-xylose	Endogenous Metabolite	Others
UDP-xylose is a natural product that could be isolated from Cryptococcus laurentii (NRRL Y-1401). UDP-xylose is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides in plants, vertebrates, and fungi .

HY-N8511

Acremine I	Fungal	Infection
Acremine I is a fungi inhibitor and also a metabolite of the endophytic fungus Acremonium byssoides. Acremine I can effectively inhibit Plasmopara viticola. Acremine I can be used for research on plant diseases, such as grape downy mildew .

HY-N7061R

Tropine (Standard)	Others	Neurological Disease
Tropine (Standard) is the analytical standard of Tropine. This product is intended for research and analytical applications. Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-N11287A

UDP-xylose disodium	Endogenous Metabolite	Others
UDP-xylose disodium is a natural product that could be isolated from Cryptococcus laurentii (N RRL Y-1401). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides in plants, vertebrates, and fungi ..

HY-N8015S2

Octanal-d4	Bacterial Endogenous Metabolite Isotope-Labeled Compounds	Cancer
Octanal-d₄ is deuterated labeled Methyl vanillate (HY-75342). Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

HY-N2625A

Harmalol hydrochloride	Cytochrome P450	Cancer
Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties .

HY-N3246

Morachalcone A	NO Synthase	Inflammation/Immunology
Morachalcone A is a naturally-occurring aromatase inhibitor (IC₅₀=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production .

HY-118614R

β-Nicotyrine (Standard)	Drug Metabolite	Neurological Disease
β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .

HY-118828A

(9S,13R)-12-Oxo phytodienoic acid (9S,13R)-12-OPDA	Lipoxygenase	Others
9S,13R)-12-Oxo phytodienoic acid is the isomerization of 12-oxo PDA (HY-118828). (9S,13R)-12-Oxo phytodienoic acid is a lipoxygenase metabolite in the leaves of green plants .

HY-N8439

Questiomycin A Phx-3	HSP Bacterial Antibiotic	Infection Cancer
Questiomycin A (Phx-3) is a GRP78 (cytoprotective endoplasmic reticulum chaperone) degrader and enhances the anticancer activity of Sorafenib. Questiomycin A is also an antimicrobial/antibiotic that can be obtained from the metabolite of Pseudomonas chlororaphis HT66. Questiomycin A can be used in research on biological control of cancer and plant diseases .

HY-N11678

Deoxynivalenol-3-β-D-glucoside DON-3-β-D-glucoside; Deoxynivalenol 3-glucoside	Drug Metabolite	Metabolic Disease
Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol (HY-N6684). Deoxynivalenol-3-β-D-glucoside exhibits lower toxicity than Deoxynivalenol in vitro and in vivo .

Cat. No.	Product Name

HY-L084

Microbial Metabolite Library

1,121 compounds

Nature has been a source of medicinal products for millennia, with many useful active substances developed from plant sources. In the 20th century, the discovery of the penicillin was the starting point for drug discovery from microbial sources. Microorganisms， which have been considered to be a rich source of unique bioactive compounds, play an important role in the development of the chemistry of natural products and medical therapy. Microbial metabolites have proved to be affective antimicrobial agents, anti-tumor agents, enzyme inhibitors, anti-inflammatory agents, etc. Today, many microbial-originated antibiotics are available in the mark, and a large number of bioactive metabolites are used in medicine.

MCE provides a unique collection of 1,121 microbial metabolites, which is an important source of lead compounds and can be used for drug discovery.

HY-L157

Animal-Sourced Natural Product Library

1,096 compounds

Natural product have great diversity and structural complexity of scaffolds. And the number of their drugs represents a large number of sources of new pharmacological entities, so natural products are of great significance in drug discovery. The Dictionary of Natural Products (DNP) shows that natural products mainly come from plants, animals and microorganisms, and animal sources are the second important source of natural products. Animal derived natural products exist to varying degrees in almost all forms of animals, generally secondary metabolite extracted from organisms.

MCE provides a unique collection of 1,096 animal-sourced natural products. MCE Animal-Sourced Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L068

Flavonoids Library

516 compounds

Flavonoids are an important class of natural products; particularly, they belong to a class of plant secondary metabolites having a polyphenolic structure, widely found in fruits, vegetables and certain beverages. Flavonoids can be subdivided into different subgroups depending on the carbon of the C ring on which the B ring is attached and the degree of unsaturation and oxidation of the C ring. These subgroups are: flavones, flavonols, flavanones, flavanonols, flavanols or catechins, anthocyanins and chalcones. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Naturally occurring flavonoids are known to have biological activities for use as drugs, for example, in diseases like cancer, Alzheimer’s disease (AD), atherosclerosis, etc.

MCE offers a unique collection of 516 natural flavonoid compounds which is a useful tool for drug discovery as an important source of lead compounds.

HY-L163

FDA-Approved Traditional Chinese Medicine Active Compound Library

332 compounds

Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability.

MCE designs a unique collection of 332 FDA-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

Cat. No.	Product Name	Category	Target	Chemical Structure