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UV

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141

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15

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13

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9

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24

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3

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15

Isotope-Labeled Compounds

4

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2

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0966

    Benzophenone-8; UV-24

    Biochemical Assay Reagents Inflammation/Immunology Cancer
    Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study .
    Dioxybenzone
  • HY-140920

    PROTAC Linkers Cancer
    UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    UV Cleavable Biotin-PEG2-Azide
  • HY-B0966S

    Benzophenone-8-d3; UV-24-d3

    Isotope-Labeled Compounds Biochemical Assay Reagents Inflammation/Immunology Cancer
    Dioxybenzone-d3 is deuterium labeled Dioxybenzone. Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study .
    Dioxybenzone-d3
  • HY-U00160
    SP187
    3 Publications Verification

    MON-​DNJ; UV4

    Flavivirus Dengue Virus Infection
    SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
    SP187
  • HY-140927

    UV Cleavable Biotin-PEG2-alkyne

    PROTAC Linkers Cancer
    Azido-C3-UV-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-C3-UV-biotin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Azido-C3-UV-biotin
  • HY-137030S

    UV-234-d4

    Isotope-Labeled Compounds Others
    2-Benzotriazol-2-yl-4,6-bis(1-methyl-1-phenylethyl)phenol-d4 (UV-234-d4) (UV-234-d4) is deuterium labeled UV-234 .
    2-Benzotriazol-2-yl-4,6-bis(1-methyl-1-phenylethyl)phenol-d4 (UV-234-d4)
  • HY-W009160S

    UV-329-d4

    Isotope-Labeled Compounds Others
    2-Benzotriazol-4-tert-octylphenol-d4 (UV-329-d4) (UV-329-d4) is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol .
    2-Benzotriazol-4-tert-octylphenol-d4 (UV-329-d4)
  • HY-B1565S

    Bumetrizole-d3-1

    Isotope-Labeled Compounds Others
    UV Absorber 326-d3 (Bumetrizole-d3-1) is deuterium labeled UV Absorber 326 .
    UV Absorber 326-d3
  • HY-B0966R

    Benzophenone-8 (Standard); UV-24 (Standard)

    Biochemical Assay Reagents Inflammation/Immunology Cancer
    Dioxybenzone (Standard) is the analytical standard of Dioxybenzone. This product is intended for research and analytical applications. Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study.
    Dioxybenzone (Standard)
  • HY-W018151S

    UV-320-d4; TinUVin-320-d4

    Isotope-Labeled Compounds Others
    2-Benzotriazol-2-yl-4,6-di-tert-butylphenol-d4 (UV-320-d4) is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4,6-di-tert-butylphenol .
    2-Benzotriazol-2-yl-4,6-di-tert-butylphenol-d4
  • HY-W014223

    Ultraviolet absorber UV-0

    Toll-like Receptor (TLR) Reactive Oxygen Species MyD88 IRAK NF-κB Inflammation/Immunology
    2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. 2,4′-Dihydroxybenzophenone is also a UV absorber .
    2,4′-Dihydroxybenzophenone
  • HY-W014937

    Drug Intermediate Cancer
    4-Hydroxybenzophenone is an intermediate for synthesizing Tamoxifen (HY-13757A) and can be used as a source for chemical synthesis, UV protection products, and UV-absorbing ingredients in cosmetics .
    4-Hydroxybenzophenone
  • HY-B1556

    NSC 6647

    Drug Derivative JNK ERK p38 MAPK Apoptosis Others
    Benzyl salicylate is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
    Benzyl salicylate
  • HY-W014223S

    Ultraviolet absorber UV-0-13C6

    Isotope-Labeled Compounds Others
    2,4-Dihydroxybenzophenone- 13C6 (Ultraviolet absorber UV-0- 13C6) is the 13C- and deuterium labeled (2,4-Dihydroxyphenyl)(phenyl)methanone[1].
    2,4-Dihydroxybenzophenone-13C6
  • HY-N3265

    MSA

    Others Others
    Methyl sinapate (MSA), a hydroxycinnamic acid, is a natural UV screening agent .
    Methyl sinapate
  • HY-W099116S

    Ultraviolet absorbent UV-1-d3

    Isotope-Labeled Compounds Others
    Ethyl 4-(((methyl(phenyl)amino)methylene)amino)benzoate-d3 (Ultraviolet absorbent UV-1-d3) is deuterium labeled Ethyl 4-(((methyl(phenyl)amino)methylene)amino)benzoate .
    Ethyl 4-(((methyl(phenyl)amino)methylene)amino)benzoate-d3
  • HY-B1556R

    Others Others
    Benzyl salicylate (Standard) is the analytical standard of Benzyl salicylate. This product is intended for research and analytical applications. Benzyl salicylate?is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
    Benzyl salicylate (Standard)
  • HY-109654

    Reactive Oxygen Species Metabolic Disease
    Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole
  • HY-D0272

    Estrogen Receptor/ERR Metabolic Disease
    2,3,4-Trihydroxybenzophenone is a hydroxylated benzophenone UV filter with estrogenic activity. 2,3,4-Trihydroxybenzophenone is also a redox mediator, which has a role as a quorum sensing inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor, a human urinary metabolite, a rat metabolite and a drug metabolite .
    2,3,4-Trihydroxybenzophenone
  • HY-D0853A
    DiAzKs hydrochloride
    1 Publications Verification

    H-L-Photo-lysine hydrochloride

    Fluorescent Dye Others
    DiAzKs (H-L-Photo-lysine) hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs hydrochloride acts as a UV light-activated photo-crosslinking probe .
    DiAzKs hydrochloride
  • HY-D0853
    DiAzKs
    1 Publications Verification

    H-L-Photo-lysine

    Fluorescent Dye Others
    DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe .
    DiAzKs
  • HY-161650

    PROTACs Epigenetic Reader Domain Cancer
    PROTAC BRD4 Degrader-26 (PROTAC-2) is a photo-regulated PROTAC, which degrades 80% BRD4 at 1 μM by using photocleavable linker. PROTAC BRD4 Degrader-26 will be deactivated by UV light. (Pink: ligand for target protein BRD4 ligand 6 (HY-161651); Black: linker (HY-161653); Blue: E3 ligase ligand Thalidomide 4-fluoride (HY-41547))
    PROTAC BRD4 Degrader-26
  • HY-155996

    PI3K Apoptosis Cancer
    FD2157 is a photosensitive PI3K inhibitor, with IC50s of 43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ respectively. FD2157 potently inhibits cancer cell proliferation and induces cell apoptosis when exposed to 365 nm UV light .
    FD2157
  • HY-A0067
    Oxybenzone
    3 Publications Verification

    Benzophenone 3

    RAR/RXR Autophagy Apoptosis Neurological Disease
    Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells .
    Oxybenzone
  • HY-W102278S

    2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d3(UV-327-d3)

    Isotope-Labeled Compounds Others
    Tinuvin-327-d3 (2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d3 (UV-327-d3)) is deuterium labeled 2,4-Di-tert-butyl-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)phenol .
    Tinuvin-327-d3
  • HY-120512

    Fluorescent Dye Others
    5-Phenyl-4E-pentenol is a product of the peroxidase-catalyzed reduction of PPHP. 5-Phenyl-4E-pentenol can be rapidly isolated by solid phase extraction and quantified by isocratic reversed-phase high performance liquid chromatography (HPLC) with UV detection. 5-Phenyl-4E-pentenol is a fluorescent dye that can be used to determine the kinetic properties of heme-containing and non-heme peroxidases and to evaluate the ability of oxidative compounds to serve as substrates for peroxidase reduction. .
    5-Phenyl-4E-pentenol
  • HY-N0428
    Obacunone
    1 Publications Verification

    Apoptosis Cancer
    Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage .
    Obacunone
  • HY-143498

    DNA/RNA Synthesis Cancer
    ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells .
    ERCC1-XPF-IN-1
  • HY-N0428R

    Apoptosis Cancer
    Obacunone (Standard) is the analytical standard of Obacunone. This product is intended for research and analytical applications. Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage .
    Obacunone (Standard)
  • HY-B0897R

    Biochemical Assay Reagents Others
    Bisoctrizole (Standard) is the analytical standard of Bisoctrizole. This product is intended for research and analytical applications. Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays.
    Bisoctrizole (Standard)
  • HY-109656

    DHHB

    Biochemical Assay Reagents Others
    Diethylamino hydroxybenzoyl hexyl benzoate is a photostable UV-A absorber.
    Diethylamino hydroxybenzoyl hexyl benzoate
  • HY-W011954

    Biochemical Assay Reagents Inflammation/Immunology
    Amiloxate is a UV-filter with anti-inflammatory activity .
    Isopentyl 3-(4-methoxyphenyl)acrylate
  • HY-17587
    4-Methylbenzylidene camphor
    1 Publications Verification

    4-MBC; Enzacamene

    Apoptosis PI3K Akt ERK Metabolic Disease
    4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
    4-Methylbenzylidene camphor
  • HY-W585837

    Endogenous Metabolite
    3-Benzylidenecamphor is a UV absorber with excellent photostability and antioxidant activity. 3-Benzylidenecamphor is widely used in sunscreen products to protect the skin from UV damage. 3-Benzylidenecamphor can also be used in cosmetics to improve the shelf life and safety of the product.
    3-Benzylidenecamphor
  • HY-109654R

    Reactive Oxygen Species Metabolic Disease
    Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole (Standard)
  • HY-B1023
    Mexenone
    1 Publications Verification

    Biochemical Assay Reagents Others
    Mexenone is a potent benzophenone-type UV filter. Mexenone is used for sunscreening agent .
    Mexenone
  • HY-109655

    Octyl triazone

    Biochemical Assay Reagents Others
    Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
    Ethylhexyl triazone
  • HY-W251181

    Tyrosinase Endocrinology
    Isobutylamido thiazolyl resorcinol is a Tyrosinase inhibitor that can prevent UV-induced pigmentation .
    Isobutylamido thiazolyl resorcinol
  • HY-D0114

    Fluorescent Dye Others
    3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye .
    3-Carboxy-7-Hydroxycoumarin
  • HY-17587R

    Apoptosis PI3K Akt ERK Metabolic Disease
    4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
    4-Methylbenzylidene camphor (Standard)
  • HY-B1234

    Octyl methoxycinnamate

    Androgen Receptor Estrogen Receptor/ERR Thyroid Hormone Receptor Cytochrome P450 Metabolic Disease Endocrinology
    Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
    Octinoxate
  • HY-W014223R

    Toll-like Receptor (TLR) Reactive Oxygen Species MyD88 IRAK NF-κB Inflammation/Immunology
    2,4′-Dihydroxybenzophenone (Standard) is the analytical standard of 2,4′-Dihydroxybenzophenone. This product is intended for research and analytical applications. 2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. 2,4′-Dihydroxybenzophenone is also a UV absorber .
    2,4′-Dihydroxybenzophenone (Standard)
  • HY-D0391

    Fluorescent Dye
    C.I Acid orange 8 is an acidic orange dye that photochemically decolorizes during a UV/hydrogen peroxide process.
    C.I Acid orange 8
  • HY-B0897
    Bisoctrizole
    1 Publications Verification

    Biochemical Assay Reagents Others
    Bisoctrizole is a broad-spectrum ultraviolet radiation absorber, absorbing UVB as well as UVA rays; also reflects and scatters UV.
    Bisoctrizole
  • HY-A0087R

    Biochemical Assay Reagents PPAR Estrogen Receptor/ERR Cytochrome P450 Others
    Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
    Octocrylene (Standard)
  • HY-B1234S

    Cytochrome P450 Thyroid Hormone Receptor Androgen Receptor Estrogen Receptor/ERR Isotope-Labeled Compounds Metabolic Disease Endocrinology
    Octinoxate-13C,d3 is the deuterium labeled Octinoxate (HY-W245806). Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
    Octinoxate-13C,d3
  • HY-117134

    Octyl palmitate

    Biochemical Assay Reagents Others
    2-Ethylhexyl palmitate is a cosmetic peptide. 2-Ethylhexyl palmitate can be used in the preparation of UV sunscreening composition .
    2-Ethylhexyl palmitate
  • HY-N3491

    Bacterial Others
    Isodictamnine is a phototoxic furoquinoline compound of the Turnipaceae family. Isodictamnine is phototoxic to certain bacteria and yeasts under long-wave UV light .
    Isodictamnine
  • HY-101897
    Fura-2 AM
    Maximum Cited Publications
    6 Publications Verification

    Fura-2 Acetoxymethyl ester

    Fluorescent Dye Others
    Fura-2 AM is a high affinity, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator.
    Fura-2 AM
  • HY-N10474

    Bacterial Others
    Obtusalin is a triterpenoid found in R. dauricum for the first time and shows UV absorption at 210 nm. Obtusalin has some antibacterial activity .
    Obtusalin

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