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Results for "

acyl-CoA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (33) Apoptosis (1) ATGL (1) Bacterial (1) Biochemical Assay Reagents (6) Drug Metabolite (2) Endogenous Metabolite (34) ERK (2) Fatty Acid Synthase (FASN) (1) Influenza Virus (1) Isotope-Labeled Compounds (4) NF-κB (1) Parasite (2) Potassium Channel (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (12) Infection (9) Inflammation/Immunology (4) Metabolic Disease (56) Neurological Disease (6)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Stearoyl-CoA Desaturase (SCD) HMG-CoA Reductase (HMGCR) Acetyl-CoA Carboxylase Acyltransferase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70009

Acyl-CoA oxidase ACO	Others	Others
Acyl-CoA oxidase (ACO) catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids and a major producer of hydrogen peroxide (H₂O₂) .

HY-113165A

Isobutyryl-L-carnitine chloride	Endogenous Metabolite	Metabolic Disease
Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases .

HY-141540

Lactyl-CoA	Others	Others
Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .

HY-134427

Palmitoyl coenzyme A lithium Palmitoyl CoA lithium	Endogenous Metabolite	Metabolic Disease
Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis .

HY-136615

5-Hydroxydecanoate sodium	Potassium Channel	Neurological Disease
5-Hydroxydecanoate sodium is a selective ATP-sensitive K ⁺ (K_ATP) channel blocker (IC₅₀ of ~30 μM). 5-Hydroxydecanoate sodium is a substrate for mitochondrial outer membrane acyl-CoA synthetase and has antioxidant activity .

HY-P2832A

Acyl-CoA Synthetase, pseudomonas fragi ACS, pseudomonas fragi	Endogenous Metabolite Fatty Acid Synthase (FASN)	Inflammation/Immunology Cancer
Acyl-CoA Synthetase, pseudomonas fragi is an acyl-CoA synthetase expressed in Pseudomonas. I Acyl-CoA Synthetase, pseudomonas fragi can catalyze the activation of fatty acids, thus maintaining cellular homeostasis. Acyl-CoA Synthetase, pseudomonas fragi can be used in research on inflammatory diseases and tumors .

HY-E70274

17:1(n7) Coenzyme A triammonium	Others	Metabolic Disease
17:1(n7) Coenzyme A triammonium is a derivative of fatty acyl-CoA .

HY-E70278

(9Z-Octadecenyl)-CoA triammonium	Biochemical Assay Reagents	Metabolic Disease
(9Z-Octadecenyl)-CoA triammonium is a coenzyme. (9Z-Octadecenyl)-CoA triammonium is a long-chain acyl-CoA esters. Long-chain acyl-CoA esters are involved in regulation of fatty acid synthesis, enzyme systems, vesicle trafficking, ion channels and ion pumps .

HY-E70246

Nonanoyl-CoA Pelargonoyl-CoA; S-Nonanoate coenzyme A	Biochemical Assay Reagents	Metabolic Disease
Nonanoyl-CoA (Pelargonoyl-CoA) is a medium-chain fatty acyl-CoA that can be used as substrate for the medium-chain hydrolase .

HY-154922

Palmitoyl coenzyme A Palmitoyl CoA	Endogenous Metabolite	Metabolic Disease
Palmitoyl coenzyme A is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A can also be used as a substrate for sphingosine biosynthesis .

HY-W783829

(2E)-Hexenoyl-CoA Hex-2-trans-enoyl-CoA	Others	Metabolic Disease
(2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA is the substrate of the enzymes enoyl-coenzyme A reductase, acyl-CoA oxidase,? acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase and Oxidoreductases .

HY-113165

Isobutyryl-L-carnitine	Endogenous Metabolite	Metabolic Disease
Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases .

HY-E70258

24:1 Coenzyme A triammonium	Biochemical Assay Reagents	Others
24:1 Coenzyme A triammonium is an acyl-CoA .

HY-115734

Phenylpyropene C S14-95	Acyltransferase	Inflammation/Immunology
Phenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC₅₀=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of *acyl-CoA, with an IC₅₀* of 16.0 μM .

HY-E70273

Tetradecyl-CoA triammonium	Endogenous Metabolite	Others
Tetradecyl-CoA triammonium is a long-chain acyl-CoA .

HY-141699

FATP1-IN-1	Others	Metabolic Disease
FATP1-IN-1 (compound 5k) is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC₅₀ values of 0.046 μM or 0.60 μM, respectively .

HY-117651

2-Fluoropalmitic acid	Acyltransferase	Cancer
2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines .

HY-W015444

2-Hydroxyoctanoic acid	Endogenous Metabolite	Metabolic Disease
2-Hydroxyoctanoic acid is a *medium chain acyl-CoA* synthetase inhibitor with a K_i** of 500 μM .

HY-E70277

Hexadecyl-CoA	ATGL	Metabolic Disease
Hexadecyl-CoA is a thioether analog of acyl-CoA that can inhibit adipose triglyceride lipase (ATGL) .

HY-N6707

Triacsin C 3 Publications Verification WS 1228A; FR 900190	Parasite	Infection
Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C is found to be highly effective against rotavirus replication .

HY-W014787

Decanedioic acid Sebacic acid	Endogenous Metabolite	Metabolic Disease
Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.

HY-N10234

Phenylpyropene A	Acyltransferase	Infection
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

HY-N8331

Terpendole I	Acyltransferase Endogenous Metabolite	Cancer
Terpendole I, a fungal indoloditerpene, is a *ACAT (acyl-CoA: cholesterol acyltransferase)* inhibitor (IC₅₀=145 µM) .

HY-N10224

Terpendole C	Acyltransferase	Metabolic Disease
Terpendole C, produced by Albophoma yamanashiensis, shows potent inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT) .

HY-113165AS

Isobutyryl-L-carnitine-d3 chloride	Endogenous Metabolite	Metabolic Disease
Isobutyryl-L-carnitine-d₃ (chloride) is the deuterium labeled Isobutyryl-L-carnitine chloride. Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases[1].

HY-E70247

(S)-3-Hydroxyhexanoyl-CoA L-3-Hydroxyhexanoyl-CoA	Endogenous Metabolite	Others
(S)-3-Hydroxyhexanoyl-CoA (L-3-Hydroxyhexanoyl-CoA) is a hydroxy fatty acyl-CoA .

HY-E70276

Heneicosanoyl-CoA	Endogenous Metabolite	Metabolic Disease
Heneicosanoyl-CoA is a substrate of Very long-chain acyl-CoA dehydrogenase (VLCAD) in the anaerobic electron transfer flavoprotein (ETF) assay .

HY-E70268

Pentacosanoyl-CoA	Biochemical Assay Reagents	Metabolic Disease
Pentacosanoyl-CoA, also known as 25:0-CoA, is a fatty acyl-CoA that can act as a substrate for AGPAT11 .

HY-107571

VULM 1457	Acyltransferase	Cardiovascular Disease Metabolic Disease
VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia .

HY-N6702

Enniatin A	Acyltransferase	Infection Cardiovascular Disease
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 22 μM in an enzyme assay using rat liver microsomes .

HY-131303

Heptadecanoyl Coenzyme A Heptadecanoyl-CoA	Biochemical Assay Reagents	Metabolic Disease
Heptadecanoyl Coenzyme A (Heptadecanoyl-CoA), long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA), is an intermediate in lipid metabolism. Heptadecanoyl Coenzyme A can be used for the research of glucose metabolism .

HY-153203

Eicosapentaenoyl-CoA triammonium 20:5 Coenzyme A triammonium	Others	Others
Eicosapentaenoyl-CoA triammonium (C20:5-CoA) is an unsaturated fatty acyl-CoA that can assist in the measurement of enzymatic activity of the TrWSD4 enzyme .

HY-113406

Hexanoylcarnitine	Others	Inflammation/Immunology
Hexanoylcarnitine exists in human urine and plasma. Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .

HY-126833B

Myristoyl coenzyme A triammonium 14:0 Coenzyme A	Others	Metabolic Disease
Myristoyl coenzyme A triammonium (14:0 Coenzyme A) is a type of long-chain acyl-CoA, which is the activated form of long-chain fatty acids and serves as a crucial lipid metabolite .

HY-119265

LDL-IN-4	Acyltransferase	Metabolic Disease
LDL-IN-4 (Compound 2) inhibits human acyl-CoA:cholesterol acyltransferase-1 and -2 activities. LDL-IN-4 inhibits copper-mediated low density lipoprotein (LDL) oxidation, with an IC₅₀ of 3 μM. LDL-IN-4 has anti-atherosclerotic biological activity .

HY-W017522

Adipic acid	Drug Metabolite Endogenous Metabolite	Metabolic Disease
Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-W014787R

Decanedioic acid (Standard)	Endogenous Metabolite	Metabolic Disease
Decanedioic acid (Standard) is the analytical standard of Decanedioic acid. This product is intended for research and analytical applications. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.

HY-32219

T863 5+ Cited Publications	Acyltransferase	Metabolic Disease
T863 is an orally active, selective and potent *DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1)* inhibitor with an IC₅₀ of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells .

HY-W014787S

Decanedioic acid-d4	Endogenous Metabolite	Metabolic Disease
Decanedioic acid-d₄ is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

HY-W014787S1

Decanedioic acid-d16	Endogenous Metabolite	Metabolic Disease
Decanedioic acid-d₁₆ is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

HY-148104

ACSS2-IN-2 1 Publications Verification	Others	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC₅₀ value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer .

HY-E70271

γ-Linolenoyl-CoA	Endogenous Metabolite	Metabolic Disease
γ-Linolenoyl-CoA (C18:3(n6)-CoA) is a fatty acyl-CoA that can be used for lipidomics analysis of fatty acid-coenzyme A (FA-CoA) through LCMS/MS .

HY-N6706

Enniatin complex	Bacterial Acyltransferase Apoptosis	Infection Cancer
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-W017522S6

Adipic acid-13C2	Isotope-Labeled Compounds	Metabolic Disease
Adipic acid- ¹³C₂ is ¹³C labeled Adipic acid. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-108341

PF-06424439 10+ Cited Publications	Acyltransferase	Metabolic Disease
PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC₅₀ of 14 nM . PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .

HY-W040790S

2,6-Dimethylpyrazine-d6	Isotope-Labeled Compounds	Others
2,6-Dimethylpyrazine-d₆ is deuterated labeled Beauvericin (HY-N6739). Beauvericin is a Fusarium mycotoxin. Beauvericin inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 3 μM in an enzyme assay using rat liver microsomes .

HY-W017522R

Adipic acid (Standard)	Drug Metabolite Endogenous Metabolite	Metabolic Disease
Adipic acid (Standard) is the analytical standard of Adipic acid. This product is intended for research and analytical applications. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-N3806

Enniatin B	Acyltransferase ERK	Infection Cardiovascular Disease Cancer
Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 113 μM in an enzyme assay using rat liver microsomes . Enniatins B decreases the activation of ERK (p44/p42) .

HY-108341A

PF-06424439 methanesulfonate 10+ Cited Publications	Acyltransferase	Metabolic Disease
PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC₅₀ of 14 nM . PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate .

HY-W017522S3

Adipic acid-13C	Endogenous Metabolite	Metabolic Disease
Adipic acid- ¹³C is the ¹³C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

Cat. No.	Product Name	Type

HY-134427

Palmitoyl coenzyme A lithium Palmitoyl CoA lithium	Drug Delivery
Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis .

HY-131303

Heptadecanoyl Coenzyme A Heptadecanoyl-CoA	Drug Delivery
Heptadecanoyl Coenzyme A (Heptadecanoyl-CoA), long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA), is an intermediate in lipid metabolism. Heptadecanoyl Coenzyme A can be used for the research of glucose metabolism .

HY-W004784

3-Butynoic acid	Biochemical Assay Reagents
3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase . 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154922

Palmitoyl coenzyme A Palmitoyl CoA	Enzyme Substrates
Palmitoyl coenzyme A is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A can also be used as a substrate for sphingosine biosynthesis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113165A

Isobutyryl-L-carnitine chloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases .

HY-W015444

2-Hydroxyoctanoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Hydroxyoctanoic acid is a *medium chain acyl-CoA* synthetase inhibitor with a K_i** of 500 μM .

HY-N6707

Triacsin C 3 Publications Verification WS 1228A; FR 900190	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite
Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C is found to be highly effective against rotavirus replication .

HY-W014787

Decanedioic acid Sebacic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.

HY-154922

Palmitoyl coenzyme A Palmitoyl CoA	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Palmitoyl coenzyme A is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A can also be used as a substrate for sphingosine biosynthesis .

HY-113165

Isobutyryl-L-carnitine	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases .

HY-N10234

Phenylpyropene A	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Acyltransferase
Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ of 0.8 μM .

HY-N8331

Terpendole I	Alkaloids Microorganisms Classification of Application Fields Terpenoids Source classification Diterpenoids Disease Research Fields Indole Alkaloids Cancer	Acyltransferase Endogenous Metabolite
Terpendole I, a fungal indoloditerpene, is a *ACAT (acyl-CoA: cholesterol acyltransferase)* inhibitor (IC₅₀=145 µM) .

HY-N10224

Terpendole C	Alkaloids Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields Indole Alkaloids	Acyltransferase
Terpendole C, produced by Albophoma yamanashiensis, shows potent inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT) .

HY-N6702

Enniatin A	Cardiovascular Disease Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Acyltransferase
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 22 μM in an enzyme assay using rat liver microsomes .

HY-113406

Hexanoylcarnitine	Structural Classification Natural Products Classification of Application Fields Animals Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Others
Hexanoylcarnitine exists in human urine and plasma. Hexanoylcarnitine can be used as a plasma detection indicator in patients with methylmalonic aciduria, propionic acidemia, and medium-chain acyl-CoA dehydrogenase deficiency .

HY-W017522

Adipic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Cancer	Drug Metabolite Endogenous Metabolite
Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-W014787R

Decanedioic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
Decanedioic acid (Standard) is the analytical standard of Decanedioic acid. This product is intended for research and analytical applications. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency.

HY-N6706

Enniatin complex	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Other Antibiotics	Bacterial Acyltransferase Apoptosis
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-W017522R

Adipic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Cardiovascular System Disorder Cancer	Drug Metabolite Endogenous Metabolite
Adipic acid (Standard) is the analytical standard of Adipic acid. This product is intended for research and analytical applications. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-N3806

Enniatin B	Infection Cardiovascular Disease Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Acyltransferase ERK
Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 113 μM in an enzyme assay using rat liver microsomes . Enniatins B decreases the activation of ERK (p44/p42) .

HY-B0399

L-Carnitine Maximum Cited Publications 13 Publications Verification (R)-Carnitine; Levocarnitine	Structural Classification Natural Products Neurological Disease Source classification Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Nervous System Disorder Disease Research Fields Cancer	Endogenous Metabolite
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B2246

L-Carnitine hydrochloride Maximum Cited Publications 13 Publications Verification (R)-Carnitine hydrochloride; Levocarnitine hydrochloride	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-N3807

Enniatin B1 1 Publications Verification	Infection Cardiovascular Disease Alkaloids Structural Classification Microorganisms Classification of Application Fields Other Alkaloids Source classification Disease Research Fields	Acyltransferase ERK NF-κB
Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 73 μM in an enzyme assay using rat liver microsomes . Enniatin B1 crosss the blood-brain barrier . Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation .

HY-B0399R

L-Carnitine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cancer	Endogenous Metabolite
L-Carnitine (Standard) is the analytical standard of L-Carnitine. This product is intended for research and analytical applications. L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B2246R

L-Carnitine hydrochloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
L-Carnitine (hydrochloride) (Standard) is the analytical standard of L-Carnitine (hydrochloride). This product is intended for research and analytical applications. L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-126455

Penicillide Vermixocin A	Monophenols Microorganisms Classification of Application Fields Source classification Phenols Metabolic Disease Disease Research Fields	Acyltransferase
Penicillide (Vermixocin A), isolated from Talaromyces derxii cultivated on rice, shows inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT) .

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Structural Classification Immune System Disorder Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

HY-N9524

Ilexoside XLVIII	Aquifoliaceae Triterpenes Structural Classification Ilex latifolia Thunb. Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Acyltransferase
Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha .

HY-W004784

3-Butynoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase . 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-113166R

Dodecanoylcarnitine (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite	Endogenous Metabolite
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine. This product is intended for research and analytical applications. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

Species:	Human (5) Mouse (1)
Tag:	His (5) Tag Free (1)
Source:	Sf9 insect cells (1) P. pastoris (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P701922

	ACSS2 Protein, Human ACSS2; Acetyl-coenzyme A synthetase; cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; acyl-CoA synthetase short-chain family member 2; acyl-activating enzyme; Propionate--CoA ligase	Human	E. coli
	The ACSS2 protein plays a key role in catalyzing the synthesis of acetyl-CoA from short-chain fatty acids, with acetate being the preferred substrate. Although acetate is efficiently utilized, ACSS2 can also process propionate, albeit with significantly lower affinity. ACSS2 Protein, Human is the recombinant human-derived ACSS2 protein, expressed by E. coli , with tag free. The total length of ACSS2 Protein, Human is 700 a.a., .

HY-P701923

	ACSS2 Protein, Human (His) ACSS2; Acetyl-coenzyme A synthetase; cytoplasmic; Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acetyl-CoA synthetase 1; AceCS1; acyl-CoA synthetase short-chain family member 2; acyl-activating enzyme; Propionate--CoA ligase	Human	E. coli
	The ACSS2 protein plays a key role in catalyzing the synthesis of acetyl-CoA from short-chain fatty acids, with acetate being the preferred substrate. Although acetate is efficiently utilized, ACSS2 can also process propionate, albeit with significantly lower affinity. ACSS2 Protein, Human (His) is the recombinant human-derived ACSS2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ACSS2 Protein, Human (His) is 700 a.a., .

HY-P76709

	ACBD7 Protein, Human (His) acyl-CoA-binding domain-containing protein 7; ACBD7	Human	E. coli
	ACBD7 Protein, pivotal in cellular metabolism, exhibits specific binding to medium- and long-chain acyl-CoA esters, hinting at a role as a molecular carrier for intracellular transport. This unique capability suggests ACBD7's involvement in regulating lipid metabolism, emphasizing its potential impact on cellular processes related to lipid homeostasis and energy metabolism. ACBD7 Protein, Human (His) is the recombinant human-derived ACBD7 protein, expressed by E. coli , with N-His labeled tag. The total length of ACBD7 Protein, Human (His) is 88 a.a., with molecular weight of ~10 kDa.

HY-P72166

	DBI Protein, Human (103a.a, His) ACBD1; ACBP; ACBP_HUMAN; acyl CoA binding domain containing 1; acyl CoA binding protein; acyl Coenzyme A binding domain containing 1; acyl coenzyme A binding protein; acyl-CoA-binding protein; CCK RP; CCKRP; Cholecystokinin releasing peptide trypsin sensitive; DBI; Diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; MGC70414	Human	E. coli
	DBI, a versatile protein, binds medium- and long-chain acyl-CoA esters, indicating a potential intracellular carrier role. It also displaces diazepam from the benzodiazepine recognition site on the GABA type A receptor. This dual functionality suggests DBI may act as a neuropeptide, modulating GABA receptor activity. Remarkably, DBI functions as a monomer in these interactions. DBI Protein, Human (103a.a, His) is the recombinant human-derived DBI protein, expressed by E. coli , with N-6*His labeled tag. The total length of DBI Protein, Human (103a.a, His) is 103 a.a., with molecular weight of ~14 kDa.

HY-P76708

	ACBD6 Protein, Human (sf9, His) acyl-CoA-binding domain-containing protein 6; ACBD6	Human	Sf9 insect cells
	ACBD6 protein selectively binds long-chain acyl-CoA, showing a significant preference for unsaturated C18:1-CoA. Unlike other variants such as unsaturated C20:4-CoA and saturated C16:0-CoA, ACBD6 does not bind to free fatty acids. ACBD6 Protein, Human (sf9, His) is the recombinant human-derived ACBD6 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ACBD6 Protein, Human (sf9, His) is 282 a.a., with molecular weight of ~36 kDa.

HY-P700627

	DBI Protein, Mouse (P. pastoris, His) Dbi; diazepam binding inhibitor; EP; Acbp; ACBD1; endozepine; acyl-CoA-binding protein; diazepam binding inhibitor, splice form 1b	Mouse	P. pastoris
	DBI Protein, with high affinity, binds medium- and long-chain acyl-CoA esters, potentially acting as an intracellular carrier. Moreover, DBI displaces diazepam from the benzodiazepine (BZD) recognition site on the GABA type A receptor, suggesting a neuropeptide role in modulating GABA receptor action. Structurally, as a monomer, DBI underscores the importance of its individual unit in diverse molecular interactions within cellular pathways. DBI Protein, Mouse (P. pastoris, His) is the recombinant mouse-derived DBI protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of DBI Protein, Mouse (P. pastoris, His) is 86 a.a., with molecular weight of 11.9 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-W017522S3

Adipic acid-13C
Adipic acid- ¹³C is the ¹³C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-W017522S

Adipic acid-d10
Adipic acid-d₁₀ is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-W017522S2

Adipic acid-d4
Adipic acid-d₄ is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-113165AS

Isobutyryl-L-carnitine-d3 chloride
Isobutyryl-L-carnitine-d₃ (chloride) is the deuterium labeled Isobutyryl-L-carnitine chloride. Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases[1].

HY-W014787S

Decanedioic acid-d4
Decanedioic acid-d₄ is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

HY-W014787S1

Decanedioic acid-d16
Decanedioic acid-d₁₆ is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

HY-W017522S6

Adipic acid-13C2
Adipic acid- ¹³C₂ is ¹³C labeled Adipic acid. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.

HY-W040790S

2,6-Dimethylpyrazine-d6
2,6-Dimethylpyrazine-d₆ is deuterated labeled Beauvericin (HY-N6739). Beauvericin is a Fusarium mycotoxin. Beauvericin inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC₅₀ of 3 μM in an enzyme assay using rat liver microsomes .

HY-W017522S1

Adipic acid-13C6
Adipic acid- ¹³C₆ is the ¹³C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-W017522S4

Adipic acid-d8
Adipic acid-d₈ is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-W017522S5

Adipic acid-d4-1
Adipic acid-d₄-1 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

HY-B0399S

L-Carnitine-d9

1 Publications Verification

L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2].

HY-B2246S

L-Carnitine-d9 chloride

L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82222

	ACADM Antibody (YA1967) ACADM; Medium-chain specific acyl-CoA dehydrogenase; mitochondrial; MCAD	WB, ICC/IF	Human, Mouse, Rat
	ACADM Antibody (YA1967) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1967), targeting ACADM, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). ACADM Antibody (YA1967) can be used for WB, ICC/IF experiment in human, mouse, rat background.

HY-P81246

	DGAT1 Antibody ACAT related gene product 1; ACAT-related gene product 1; acyl coenzyme A:cholesterol acyltransferase related gene 1; acyl-CoA retinol O-fatty-acyltransferase; acyl-CoA:diacylglycerol acyltransferase; ARAT; ARGP1; C75990; D15Ertd23e; Dgat; DGAT1; DGAT1_HUMAN; Diacylglycerol O acyltransferase 1; Diacylglycerol O-acyltransferase 1; Diglyceride acyltransferase; EC 2.3.1.20; hCG_24006; MGC139064; Retinol O fatty acyltransferase.	WB, IHC-P, IP	Human
	DGAT1 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting DGAT1, with a predicted molecular weight of 55 kDa (observed band size: 55 kDa). DGAT1 Antibody can be used for WB,IHC-P,IP experiments in human backgrounds.

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Cat. No.	Product Name		Classification

HY-W004784

3-Butynoic acid		Alkynes
3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase . 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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