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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

cell biology

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (1) Bcl-2 Family (1) Biochemical Assay Reagents (23) Caspase (1) Endogenous Metabolite (2) ERK (1) Fluorescent Dye (6) Gap Junction Protein (1) HDAC (1) Histone Acetyltransferase (1) Influenza Virus (2) Isotope-Labeled Compounds (3) Keap1-Nrf2 (1) Liposome (1) MALT1 (1) NF-κB (1) Parasite (2) Photosensitizer (2) PI3K (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (5) Infection (3) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	pH Modifiers (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor VISTA BCL6 Tim3 BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1683

NBD-PE	Fluorescent Dye	Others
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .

HY-D0895

3,4,5,6-Tetrabromophenolsulfonephthalein	Fluorescent Dye	Others
3,4,5,6-Tetrabromophenolsulfonephthalein is a stain for cell biology .

HY-Y0344D

Sodium chloride, for cell culture Halite, for cell culture	Biochemical Assay Reagents	Others
Sodium chloride, for cell culture, for molecular biology, an inorganic salt, is a biochemical reagent that can be used for molecular biology.

HY-D0830

Calcein (tetraethyl ester) Fluorexon tetraethyl ester	Fluorescent Dye	Others
Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.

HY-D0859A

MOPS sodium salt	Biochemical Assay Reagents	Others
MOPS sodium salt is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media .

HY-D0166A

Neutral Red (IND)	Biochemical Assay Reagents	Others
Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.

HY-P0239

HA Peptide Maximum Cited Publications 9 Publications Verification	Influenza Virus	Inflammation/Immunology
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-P0239A

HA Peptide TFA Maximum Cited Publications 9 Publications Verification	Influenza Virus	Inflammation/Immunology
HA Peptide (TFA) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide (TFA) is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry .

HY-W414447

Disperse blue 1 DB1	Biochemical Assay Reagents	Others
Disperse blue 1 is an organic dye. Disperse blue 1 can be used in staining experiments in biology to stain cells and tissues .

HY-D0859S

MOPS-d15	Isotope-Labeled Compounds	Others
MOPS-d₁₅ is the deuterium labeled MOPS[1]. MOPS is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media[2][3].

HY-P10421

PKCδ substrate	ERK	Cancer
PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involved in the regulation of cell growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. PKCδ substrate can be used to study the development of diseases, especially cancer biology .

HY-169838

WYneC	Biochemical Assay Reagents	Others
WYneC can specifically bind to sulfinylated proteins in living cells and then react with fluorescent probes containing azide groups for detection. In the field of redox biology, WYneC can also be used to determine the occupancy of S-sulfinylation sites or as a carrier to deliver substances to mitochondria .

HY-D0859

MOPS	Biochemical Assay Reagents	Others
MOPS are commonly used as buffers in biology. MOPS buffer maintains the pH of mammalian cell culture media. MOPS and Tris buffer also have inhibitory effects on TfCut2 and LCC hydrolases, inhibiting the rate of hydrolyzing PET films. MOPS may also interfere with calcium binding, translocation, and utilization in vascular smooth muscle cells .

HY-D0858B

MES sodium salt 1 Publications Verification 2-Morpholinoethanesulphonic acid sodium salt	Biochemical Assay Reagents	Others
MES sodium salt (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES sodium salt is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858C

MES hydrate 1 Publications Verification 2-Morpholinoethanesulphonic acid hydrate	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) hydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES hydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858E

MES potassium 1 Publications Verification 2-Morpholinoethanesulphonic acid potassium	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) potassium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES potassium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858

MES 1 Publications Verification 2-Morpholinoethanesulphonic acid	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858A

MES monohydrate 1 Publications Verification 2-Morpholinoethanesulphonic acid monohydrate	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) monohydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES monohydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-W587552

1,3-Diolein	Liposome Endogenous Metabolite
1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds.

HY-D0858D

MES hemisodium 1 Publications Verification 2-Morpholinoethanesulphonic acid hemisodium	Biochemical Assay Reagents	Others
MES (2-Morpholinoethanesulphonic acid) hemisodium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES hemisodium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-E70371

Cre recombinase	Biochemical Assay Reagents	Others
Cre recombinase is a resolvase derived from the P1 bacteriophage. Cre recombinase catalyzes site-specific recombination between two loxP DNA sequences, converts dimers of P1 chromosome into monomers before cell division. Cre recombinase is utilized in genetic engineering and molecular biology applications .

HY-D1886

Vari Fluor 647 SE	Fluorescent Dye	Others
Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

HY-W127628

Decyl β-D-glucopyranoside	Biochemical Assay Reagents	Others
Decyl β-D-glucopyranoside is a nonionic surfactant commonly used in biochemical and molecular biology research. It can be used for the extraction, purification and structural analysis of cell membranes, and is widely used in the fields of proteomics and genetic engineering. In addition, this compound is also used as an auxiliary reagent and dehydrating agent in some biochemical experiments.

HY-169789

PKN3-IN-1	PI3K	Metabolic Disease Cancer
PKN3-IN-1 (compound 16) inhibits PKN3 (serine/threonine protein kinase 3) and GAK (cyclin G-associated kinase) with IC₅₀ of 0.014 μM and K_i of 0.0044 μM respectively. PKN3-IN-1 is a potential tool compound to study the cell biology of PKN3 and its role in pancreatic and prostate cancer and T-cell acute lymphoblastic leukemia .

HY-W011577

Benzo[f]tetraphene Dibenz[a,c]anthracene	Photosensitizer
Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.

HY-W088069

Dipotassium hydrogen phosphate trihydrate	Biochemical Assay Reagents	Others
Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.

HY-D0858S

MES-d13	Isotope-Labeled Compounds Biochemical Assay Reagents	Others
MES-d₁₃ is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858AR

MES (monohydrate) (Standard) 2-Morpholinoethanesulphonic acid (monohydrate) (Standard)	Biochemical Assay Reagents	Others
MES (monohydrate) (Standard) is the analytical standard of MES (monohydrate). This product is intended for research and analytical applications. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-P5295

Cy3-Ova (323-339)	Fluorescent Dye	Others
Cy3-Ova (323-339) is an Cy3 labled OVA Peptide (323-339) (HY-P0286). Cy3 is a fluorescent dye belonging to the Cyanine family and is a fluorescent light product of Cy5. Cyanine is commonly used in fluorescence microscopy, cell imaging, and molecular biology experiments. OVA Peptide (323-339) represents the T and B cell epitopes of ovalbumin (OVA). OVA Peptide (323-339) has limited immunogenic efficacy in activating OVA-sensitized and attacked mouse spleen cells .

HY-P1138

Scrambled 10Panx FSVYWAQADR	Gap Junction Protein	Others
Scrambled 10Panx (FSVYWAQADR) is a random sequence variant of a specific inhibitory peptide 10Panx targeted at the half-channel of Pannexin-1 (Panx1). Scrambled 10Panx is used as a control peptide to determine whether other experimental conditions or peptides act through specific molecular mechanisms. Scrambled 10Panx can be used for research in neurobiology and cell biology .

HY-109521A

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) Manganese(Ⅱ) chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)	Biochemical Assay Reagents Histone Acetyltransferase HDAC	Neurological Disease
Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.

HY-112697

Rhodamine B isothiocyanate	Biochemical Assay Reagents	Others
Rhodamine B isothiocyanate (RBITC) is a fluorescent dye commonly used in biological imaging and labeling applications. It has an isothiocyanate functional group that can be covalently attached to amino groups on proteins and other biomolecules, making it useful for fluorescent labeling of cells and tissues. RBITC fluoresces bright orange-red under green light excitation, which makes it easy to detect and track labeled molecules in complex samples. Due to its stability and sensitivity, RBITC has been widely used in various research fields, including cell biology, immunology, and neurobiology.

HY-W181026

KLF10-IN-1	Fluorescent Dye	Inflammation/Immunology
KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC₅₀ value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25 T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology .

HY-116535B

DL-threo-PPMP	Parasite	Infection
DL-threo-PPMP is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP inhibits the activity of sphingosine synthetase by mimicking the substrate sphingosine. This inhibition leads to a rapid decrease in the activity of sensitive sphingosine synthetase, selectively destroying the interconnected tubular network of TVMs in the host cell cytoplasm, and this inhibition also blocks the proliferation of Plasmodium falciparum. DL-threo-PPMP can be used for the study of Plasmodium biology and the search for new antimalarial strategies .

HY-116535A

DL-threo-PPMP hydrochloride	Parasite	Infection
DL-threo-PPMP hydrochloride is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP hydrochloride inhibits the activity of sphingosine synthetase (sphingosine synthetase) by binding to a substrate that mimics sphingosine. This inhibition leads to a rapid decline in sensitive sphingomyelin synthase (SSS) activity, selectively disrupting the interconnected tubular network of TVM in the cytoplasm of the host cell, and this inhibition also blocks the proliferation of the parasite. DL-threo-PPMP hydrochloride can be used in the study of malaria parasite biology and the search for new antimalarial strategies .

HY-N10264

Avrainvillamide (+)-Avrainvillamide; CJ-17,665	Antibiotic	Infection Cancer
Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .

HY-W011577S1

Dibenzo[a,c]anthracene-13C6 2,3-Benzotriphenylene-¹³C₆	Isotope-Labeled Compounds Photosensitizer	Cancer
Dibenzo[a,c]anthracene- ¹³C₆ (2,3-Benzotriphenylene- ¹³C₆) is ¹³C labeled Benzo[f]tetraphene. Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.

HY-W010572

1-Thioglycerol alpha-Thioglycerol	Biochemical Assay Reagents	Others
1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.

HY-W127409

1,2-Dimyristoyl-rac-glycerol	Biochemical Assay Reagents	Others
1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

HY-121282B

Mepazine acetate Pecazine acetate	Apoptosis MALT1	Others
Mepazine acetate (Pecazine acetate) is a drug that has the activity to inhibit the protease activity of MALT1. Mepazine acetate is often used to study the role of MALT1 in biology. Treatment of mouse bone marrow precursor cells with mepazine acetate strongly inhibited RANK ligand (RANKL)-induced osteoclast formation. Mepazine acetate also inhibited the expression of multiple osteoclast markers such as TRAP, feline hepsin K, and calcitonin. The protective effect of mepazine acetate was not affected by MALT1 deficiency. The mechanism of action of mepazine acetate may involve MALT1-independent mechanisms, and this aspect needs to be considered in future studies .

HY-W342092

1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril	Biochemical Assay Reagents Endogenous Metabolite
1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is a chemical agent that has the property of inhibiting enzyme activity in organisms. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is used as a potential anti-tumor agent in compound development. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril has the effect of regulating cell signaling pathways and can be used to study cell biology. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is considered to be a potent compound that can exert biological activity under specific conditions.

HY-13755A

(R)-Sulforaphane L-Sulforaphane	Keap1-Nrf2 Bcl-2 Family Caspase Reactive Oxygen Species NF-κB	Inflammation/Immunology Cancer
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .

HY-W010572R

1-Thioglycerol (Standard)	Biochemical Assay Reagents	Others
1-Thioglycerol (Standard) is the analytical standard of 1-Thioglycerol. This product is intended for research and analytical applications. 1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.

Cat. No.	Product Name

HY-L179

Radiosensitizer Library	41 compounds
Radiotherapy is a common treatment for various cancers, and more than 50% of cancer patients require radiotherapy during the disease treatment. With advances in radiation technology and a better understanding of tumor biology, the efficacy of radiation therapy has gradually improved, and more and more patients have benefited from it. However, even with the use of advanced radiotherapy techniques, there are still many malignant tumor cells with low sensitivity to radiation, leading to the radiation effect is not ideal. To solve this problem, radiosensitizers have received more and more attention. Radiosensitizer is a kind of drug that can enhance the radiosensitivity of tumor cells and improve the effect of radiotherapy. Radiation sensitizers act in a variety of ways, such as killing hypoxic cells, enhancing DNA damage, inhibiting DNA damage repair, and blocking cell cycle progression, making tumor cells more susceptible to radiation damage and death than surrounding normal cells. MCE designs a unique collection of 41 compounds with definite reported radiosensitization. It can be used for drug combination research in anti-cancer treatment.

Radiosensitizer Library

41 compounds

Radiotherapy is a common treatment for various cancers, and more than 50% of cancer patients require radiotherapy during the disease treatment. With advances in radiation technology and a better understanding of tumor biology, the efficacy of radiation therapy has gradually improved, and more and more patients have benefited from it. However, even with the use of advanced radiotherapy techniques, there are still many malignant tumor cells with low sensitivity to radiation, leading to the radiation effect is not ideal. To solve this problem, radiosensitizers have received more and more attention. Radiosensitizer is a kind of drug that can enhance the radiosensitivity of tumor cells and improve the effect of radiotherapy. Radiation sensitizers act in a variety of ways, such as killing hypoxic cells, enhancing DNA damage, inhibiting DNA damage repair, and blocking cell cycle progression, making tumor cells more susceptible to radiation damage and death than surrounding normal cells.

MCE designs a unique collection of 41 compounds with definite reported radiosensitization. It can be used for drug combination research in anti-cancer treatment.

HY-L072

Exosomes Compound Library	50 compounds
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining. The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 50 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Exosomes Compound Library

50 compounds

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 50 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Cat. No.	Product Name	Type

HY-D1683

NBD-PE	Fluorescent Dyes/Probes
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .

HY-D0830

Calcein (tetraethyl ester) Fluorexon tetraethyl ester	Fluorescent Dyes/Probes
Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.

HY-D0166A

Neutral Red (IND)

Dyes

Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant. Although the compound has no direct medical application, it has important application value in the fields of biology, chemistry and industry.

HY-D1886

Vari Fluor 647 SE

Fluorescent Dyes/Probes

Vari Fluor 647 SE is a fluorescent dye, SE stands for "succinimidyl ester". Vari Fluor 647 SE belongs to the Vari Fluor family of labeling reagents used in cell and molecular biology research. Vari Fluor 647 SE can react with an amino group to form a covalent bond, thereby introducing Vari Fluor 647 dye into the target molecule or cell. Vari Fluor 647 SE is a reactive dye that produces a fluorescent signal after binding to a target molecule or cell.

HY-112697

Rhodamine B isothiocyanate

Dyes

Rhodamine B isothiocyanate (RBITC) is a fluorescent dye commonly used in biological imaging and labeling applications. It has an isothiocyanate functional group that can be covalently attached to amino groups on proteins and other biomolecules, making it useful for fluorescent labeling of cells and tissues. RBITC fluoresces bright orange-red under green light excitation, which makes it easy to detect and track labeled molecules in complex samples. Due to its stability and sensitivity, RBITC has been widely used in various research fields, including cell biology, immunology, and neurobiology.

Cat. No.	Product Name	Type

HY-Y0344D

Sodium chloride, for cell culture Halite, for cell culture	Buffer Reagents
Sodium chloride, for cell culture, for molecular biology, an inorganic salt, is a biochemical reagent that can be used for molecular biology.

HY-D0859A

MOPS sodium salt	Buffer Reagents
MOPS sodium salt is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media .

HY-D0858B

MES sodium salt 1 Publications Verification 2-Morpholinoethanesulphonic acid sodium salt	Buffer Reagents
MES sodium salt (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES sodium salt is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858C

MES hydrate 1 Publications Verification 2-Morpholinoethanesulphonic acid hydrate	Buffer Reagents
MES (2-Morpholinoethanesulphonic acid) hydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES hydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858E

MES potassium 1 Publications Verification 2-Morpholinoethanesulphonic acid potassium	Buffer Reagents
MES (2-Morpholinoethanesulphonic acid) potassium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES potassium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858

MES 1 Publications Verification 2-Morpholinoethanesulphonic acid	Buffer Reagents
MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858A

MES monohydrate 1 Publications Verification 2-Morpholinoethanesulphonic acid monohydrate	Buffer Reagents
MES (2-Morpholinoethanesulphonic acid) monohydrate is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES monohydrate is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858D

MES hemisodium 1 Publications Verification 2-Morpholinoethanesulphonic acid hemisodium	Biochemical Assay Reagents
MES (2-Morpholinoethanesulphonic acid) hemisodium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES hemisodium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0858AR

MES (monohydrate) (Standard)

2-Morpholinoethanesulphonic acid (monohydrate) (Standard)

Buffer Reagents

MES (monohydrate) (Standard) is the analytical standard of MES (monohydrate). This product is intended for research and analytical applications. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-W127628

Decyl β-D-glucopyranoside	Surfactants
Decyl β-D-glucopyranoside is a nonionic surfactant commonly used in biochemical and molecular biology research. It can be used for the extraction, purification and structural analysis of cell membranes, and is widely used in the fields of proteomics and genetic engineering. In addition, this compound is also used as an auxiliary reagent and dehydrating agent in some biochemical experiments.

HY-109521A

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)

Manganese(Ⅱ) chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)

Buffer Reagents

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.

HY-W739644

1-Linoleoyl-2-oleoyl-3-stearoyl-rac-glycerol

Drug Delivery

1-Linoleoyl-2-oleoyl-3-stearoyl-rac-glycerol is a triacylglycerol molecule with biological activity that promotes lipid droplet formation. The fatty acid combination of 1-Linoleoyl-2-oleoyl-3-stearoyl-rac-glycerol makes it an important tool for studying the effects of fatty acids. 1-Linoleoyl-2-oleoyl-3-stearoyl-rac-glycerol has a wide range of applications in cell biology and metabolic research.

HY-W010572

1-Thioglycerol

alpha-Thioglycerol

Biochemical Assay Reagents

1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.

HY-W127409

1,2-Dimyristoyl-rac-glycerol

Drug Delivery

1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

HY-W010572R

1-Thioglycerol (Standard)

Biochemical Assay Reagents

1-Thioglycerol (Standard) is the analytical standard of 1-Thioglycerol. This product is intended for research and analytical applications. 1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.

Cat. No.	Product Name	Target	Research Area

HY-P0239

HA Peptide 5+ Cited Publications	Influenza Virus	Inflammation/Immunology
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-P0239A

HA Peptide TFA 5+ Cited Publications	Influenza Virus	Inflammation/Immunology
HA Peptide (TFA) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide (TFA) is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry .

HY-P10421

PKCδ substrate	ERK	Cancer
PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involved in the regulation of cell growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. PKCδ substrate can be used to study the development of diseases, especially cancer biology .

HY-P5295

Cy3-Ova (323-339)	Fluorescent Dye	Others
Cy3-Ova (323-339) is an Cy3 labled OVA Peptide (323-339) (HY-P0286). Cy3 is a fluorescent dye belonging to the Cyanine family and is a fluorescent light product of Cy5. Cyanine is commonly used in fluorescence microscopy, cell imaging, and molecular biology experiments. OVA Peptide (323-339) represents the T and B cell epitopes of ovalbumin (OVA). OVA Peptide (323-339) has limited immunogenic efficacy in activating OVA-sensitized and attacked mouse spleen cells .

HY-P1138

Scrambled 10Panx FSVYWAQADR	Gap Junction Protein	Others
Scrambled 10Panx (FSVYWAQADR) is a random sequence variant of a specific inhibitory peptide 10Panx targeted at the half-channel of Pannexin-1 (Panx1). Scrambled 10Panx is used as a control peptide to determine whether other experimental conditions or peptides act through specific molecular mechanisms. Scrambled 10Panx can be used for research in neurobiology and cell biology .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P0239

HA Peptide 5+ Cited Publications	Natural Products Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Influenza Virus
HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry.

HY-P0239A

HA Peptide TFA 5+ Cited Publications	Natural Products Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Influenza Virus
HA Peptide (TFA) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide (TFA) is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry .

HY-N10264

Avrainvillamide (+)-Avrainvillamide; CJ-17,665	Infection Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Antibiotic
Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .

HY-13755A

(R)-Sulforaphane L-Sulforaphane	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Keap1-Nrf2 Bcl-2 Family Caspase Reactive Oxygen Species NF-κB
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .

Cat. No.	Product Name	Chemical Structure

HY-D0858S

MES-d13
MES-d₁₃ is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies .

HY-D0859S

MOPS-d15
MOPS-d₁₅ is the deuterium labeled MOPS[1]. MOPS is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media[2][3].

HY-W011577S1

Dibenzo[a,c]anthracene-13C6

Dibenzo[a,c]anthracene- ¹³C₆ (2,3-Benzotriphenylene- ¹³C₆) is ¹³C labeled Benzo[f]tetraphene. Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.

Cat. No.	Product Name		Classification

HY-W088069

Dipotassium hydrogen phosphate trihydrate		pH Modifiers
Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.

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